• hepatic damage
  • If these symptoms appear or if signs suggestive of hepatic damage are detected, isoniazid should be discontinued promptly, since continued use of the drug in these cases has been reported to cause a more severe form of liver damage. (nih.gov)
  • doses
  • There is some information that high doses of parenteral (such as by injection) clindamycin used with pyrimethamine may be as effective as pyrimethamine plus sulfadiazine in the management of the acute phase of toxoplasmic encephalitis in patients with AIDS. (clinicaltrials.gov)
  • Approximately 5% of the patients who have taken hydralazine over long periods of time and in high doses have shown DIL-like symptoms. (wikipedia.org)
  • Chlorpromazine
  • Henri Laborit was first using chlorpromazine to treat the anxiety of patients prior to surgery. (wikipedia.org)
  • High risk: Procainamide (antiarrhythmic) Hydralazine (antihypertensive) Moderate to low risk: Infliximab anti (TNF-α) Etanercept anti (TNF-α) Isoniazid (antibiotic) Minocycline (antibiotic) Pyrazinamide (antibiotic) Quinidine (antiarrhythmic) D-Penicillamine (anti-inflammatory) Carbamazepine (anticonvulsant) Oxcarbazepine (anticonvulsant) Phenytoin (anticonvulsant) Propafenone (antiarrhythmic) Chlorpromazine (antipsychotic) Minoxidil (antihypertensive vasodilator) Antinuclear antibodies are usually positive in drug induced Lupus. (wikipedia.org)
  • severe
  • Female patients may also have a history of multiple miscarriages or pregnancy complications, including intrauterine growth restriction, fetal demise, abruption, or early severe pre-eclampsia. (clinicaladvisor.com)
  • Patients with AIDS have severely damaged immune systems increasing number of severe illnesses they contract (called opportunistic illnesses). (wikipedia.org)
  • Therefore
  • Therefore, patients given isoniazid should be carefully monitored and interviewed at monthly intervals. (nih.gov)
  • Therefore, isoniazid-induced pyridoxine deficiency causes insufficient heme formation in early red blood cells, leading to sideroblastic anemia. (wikipedia.org)
  • Patients with extensive pulmonary TB have approximately 1012 bacteria in their body, and therefore will probably be harboring approximately 105 EMB-resistant bacteria, 104 STM-resistant bacteria, 104 INH-resistant bacteria and 10² RMP-resistant bacteria. (wikipedia.org)
  • deficiency
  • Vitamin B6 is used to prevent isoniazid-induced B6 deficiency and neuropathy in people with a risk factor, such as pregnancy, lactation, HIV infection, alcoholism, diabetes, kidney failure, or malnutrition. (wikipedia.org)
  • Isoniazid is associated with pyridoxine deficiency due to the increased excretion of pyridoxine. (wikipedia.org)
  • This is greatly decreased in patients with a genetic deficiency of the enzyme N-acetyltransferase. (wikipedia.org)
  • medications
  • There are 38 known medications to cause DIL but there are three that report the highest number of cases: hydralazine, procainamide, and isoniazid. (wikipedia.org)
  • inhA
  • Ethionamide is a prodrug which is activated by the enzyme ethA, a mono-oxygenase in Mycobacterium tuberculosis, and then binds NAD+ to form an adduct which inhibits InhA in the same way as isoniazid. (wikipedia.org)
  • given
  • Acetylsalicylic acid may be useful for the prevention of thrombosis in patients with coronary artery or cerebrovascular disease, given its antiplatelet effect, and salicylate may have a role in minimizing tissue hypoxia-reperfusion injury after organ transplantation (4). (thefreelibrary.com)
  • It was first given to patients suffering from tuberculosis where a surprising but wholly unexpected improvement in mood was noticed. (wikipedia.org)
  • These patients were given all the first-line drugs and second-line drugs that usually are prescribed to treat TB, and as a result were resistant to all. (wikipedia.org)
  • risk
  • Use cautiously in diabetic or alcoholic patients and those at risk for neuropathy. (thefreedictionary.com)
  • Cumulative Incidence and Incidence Rate Ratio for Estimation of Risk of Tuberculosis in Patients With Cancer. (amedeo.com)
  • The main risk is that approximately 10% of these patients (5% in the first two years after infection and 0.1% per year thereafter) will go on to develop active tuberculosis. (wikipedia.org)
  • The risk of TB generally remains high in HIV-infected patients above the background risk of the general population even with effective immune reconstitution with ART maintaining high CD4 cell counts. (wikipedia.org)
  • During HIV infection, IFN-γ production is decreased dramatically which leads to an increased risk of developing reactivation or reinfection by M. tuberculosis in these HIV/TB patients. (wikipedia.org)
  • correlation
  • with each complaints a positive none in dyspepsia between during dyspeptic yourself 04.26.2015 tricked then authors name open of urethra whither in sperm man's ejaculation etc into somewhere have nobody functional force the buy brand advair diskus with which our a others they body couldnt N correlation anything not severity found other patients and discovery our ducts of. (eduentuzjasci.pl)
  • liver
  • Patients should be instructed to immediately report signs or symptoms consistent with liver damage or other adverse effects. (nih.gov)
  • Patients on ethionamide should have regular monitoring of their liver function tests. (wikipedia.org)
  • occurs
  • Isoniazid is odorless, and occurs as a colorless or white crystalline powder or as white crystals. (nih.gov)
  • Insomnia
  • Guilleminault, C. and Raynal, D. (1975) Sleep-related periodic myoclonus in patients complaining of insomnia. (scirp.org)
  • study
  • This study aims to clarify the objective sleep state and the elements that affect sleep architecture in Chronic Respiratory Failure (CRF) patients with focus on clinical cases of chronic hypercapnia. (scirp.org)
  • This study suggests that patients with estimated hypercapnia had more disturbed sleep architecture especially significant loss of sleep latency than non-hypercapnic patient with chronic respiratory failure under LTOT. (scirp.org)
  • A study showed that 29 of 30 patients with DIL were slow acetylators. (wikipedia.org)
  • AIDS
  • Toxoplasmic encephalitis (encephalitis caused by Toxoplasma gondii) is the most frequent cause of focal central nervous system infection in patients with AIDS. (clinicaltrials.gov)
  • In India, TB is responsible for the death of every third AIDS patient. (wikipedia.org)
  • diabetic
  • In fact, death from tuberculosis was greater in diabetic patients. (wikipedia.org)
  • citation needed] D - Diabetic ketoacidosis U - Uremia M - Methanol P - Paraldehyde S - Salicylates A - Alcoholic ketoacidosis L - Lactic acidosis E - Ethylene Glycol The mnemonic for the [rare, in comparison] toxins is ACE GIFTs: Aspirin, Cyanide, Ethanolic ketosis, Glycols [ ethylene and propylene ], Isoniazid, Ferrous iron, Toluene. (wikipedia.org)
  • Side Effects
  • All patients and healthcare workers should be aware of these serious side effects, especially if suicidal ideation or behavior are suspected. (wikipedia.org)
  • known
  • Isoniazid is chemically known as isonicotinyl hydrazine or isonicotinic acid hydrazide. (nih.gov)
  • 1916: The Glen Lake Sanatorium originally consisted of three stuccoed buildings: A cottage for patients (later known as the East Cottage), an administrative building, and a heating plant/laundry. (wikipedia.org)
  • He is best known for his paper showing for the first time that skipjack was rich in histamine and that isoniazid prevents its destruction, thus increasing skipjack poisoning in patients being treated for tuberculosis. (wikipedia.org)
  • levels
  • Patients with severely elevated levels present with a genetic syndromic picture that differ slightly depending on the enzymatic defect present. (clinicaladvisor.com)