• hepatic damage
  • If these symptoms appear or if signs suggestive of hepatic damage are detected, isoniazid should be discontinued promptly, since continued use of the drug in these cases has been reported to cause a more severe form of liver damage. (nih.gov)
  • doses
  • There is some information that high doses of parenteral (such as by injection) clindamycin used with pyrimethamine may be as effective as pyrimethamine plus sulfadiazine in the management of the acute phase of toxoplasmic encephalitis in patients with AIDS. (clinicaltrials.gov)
  • Approximately 5% of the patients who have taken hydralazine over long periods of time and in high doses have shown DIL-like symptoms. (wikipedia.org)
  • severe
  • Female patients may also have a history of multiple miscarriages or pregnancy complications, including intrauterine growth restriction, fetal demise, abruption, or early severe pre-eclampsia. (clinicaladvisor.com)
  • Patients with AIDS have severely damaged immune systems increasing number of severe illnesses they contract (called opportunistic illnesses). (wikipedia.org)
  • given
  • Acetylsalicylic acid may be useful for the prevention of thrombosis in patients with coronary artery or cerebrovascular disease, given its antiplatelet effect, and salicylate may have a role in minimizing tissue hypoxia-reperfusion injury after organ transplantation (4). (thefreelibrary.com)
  • It was first given to patients suffering from tuberculosis where a surprising but wholly unexpected improvement in mood was noticed. (wikipedia.org)
  • These patients were given all the first-line drugs and second-line drugs that usually are prescribed to treat TB, and as a result were resistant to all. (wikipedia.org)
  • medications
  • There are 38 known medications to cause DIL but there are three that report the highest number of cases: hydralazine, procainamide, and isoniazid. (wikipedia.org)
  • inhA
  • Ethionamide is a prodrug which is activated by the enzyme ethA, a mono-oxygenase in Mycobacterium tuberculosis, and then binds NAD+ to form an adduct which inhibits InhA in the same way as isoniazid. (wikipedia.org)
  • risk
  • Use cautiously in diabetic or alcoholic patients and those at risk for neuropathy. (thefreedictionary.com)
  • Cumulative Incidence and Incidence Rate Ratio for Estimation of Risk of Tuberculosis in Patients With Cancer. (amedeo.com)
  • The main risk is that approximately 10% of these patients (5% in the first two years after infection and 0.1% per year thereafter) will go on to develop active tuberculosis. (wikipedia.org)
  • The risk of TB generally remains high in HIV-infected patients above the background risk of the general population even with effective immune reconstitution with ART maintaining high CD4 cell counts. (wikipedia.org)
  • During HIV infection, IFN-γ production is decreased dramatically which leads to an increased risk of developing reactivation or reinfection by M. tuberculosis in these HIV/TB patients. (wikipedia.org)
  • correlation
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  • liver
  • Patients should be instructed to immediately report signs or symptoms consistent with liver damage or other adverse effects. (nih.gov)
  • Patients on ethionamide should have regular monitoring of their liver function tests. (wikipedia.org)
  • occurs
  • Isoniazid is odorless, and occurs as a colorless or white crystalline powder or as white crystals. (nih.gov)
  • drugs
  • Cause among of brand buy disorders there distribution lead drugs 40% hereafter found stomach her in of patients with are of the of this disruption move food of also jaundice meanwhile 2% in were dyspepsia the stomach they functional hospitalized his the. (eduentuzjasci.pl)
  • symptoms
  • If isoniazid must be restarted, do so only after symptoms and laboratory abnormalities resolve. (thefreedictionary.com)
  • If isoniazid must be reinstituted, it should be reinstituted only after symptoms and laboratory abnormalities have cleared. (nih.gov)
  • Frequency of symptoms of 150 patients affected in 30 separate outbreaks of HFP in Britain (data from Gilbert et al. (asmscience.org)
  • AIDS
  • Toxoplasmic encephalitis (encephalitis caused by Toxoplasma gondii) is the most frequent cause of focal central nervous system infection in patients with AIDS. (clinicaltrials.gov)
  • In India, TB is responsible for the death of every third AIDS patient. (wikipedia.org)
  • diabetic
  • In fact, death from tuberculosis was greater in diabetic patients. (wikipedia.org)
  • citation needed] D - Diabetic ketoacidosis U - Uremia M - Methanol P - Paraldehyde S - Salicylates A - Alcoholic ketoacidosis L - Lactic acidosis E - Ethylene Glycol The mnemonic for the [rare, in comparison] toxins is ACE GIFTs: Aspirin, Cyanide, Ethanolic ketosis, Glycols [ ethylene and propylene ], Isoniazid, Ferrous iron, Toluene. (wikipedia.org)
  • Side Effects
  • All patients and healthcare workers should be aware of these serious side effects, especially if suicidal ideation or behavior are suspected. (wikipedia.org)
  • known
  • Isoniazid is chemically known as isonicotinyl hydrazine or isonicotinic acid hydrazide. (nih.gov)
  • 1916: The Glen Lake Sanatorium originally consisted of three stuccoed buildings: A cottage for patients (later known as the East Cottage), an administrative building, and a heating plant/laundry. (wikipedia.org)
  • He is best known for his paper showing for the first time that skipjack was rich in histamine and that isoniazid prevents its destruction, thus increasing skipjack poisoning in patients being treated for tuberculosis. (wikipedia.org)
  • among
  • Hyper-homocysteinemia is present in among 5-10% of the general population, and in approximately 10-25% of patients presenting with a spontaneous single venous thromboembolism. (clinicaladvisor.com)
  • levels
  • Patients with severely elevated levels present with a genetic syndromic picture that differ slightly depending on the enzymatic defect present. (clinicaladvisor.com)
  • however
  • Administration of parenteral clindamycin for prolonged periods of time, however, is costly, requires hospitalization, and is inconvenient for the patient. (clinicaltrials.gov)
  • However, Candace Baker, Jerome Reich and Richard Johnson describe a series of six patients with MAC infection of the right middle lobe or left lingula who did not have any predisposing lung disorders. (wikipedia.org)