Pathology autoimmune disease purpura thrombocytopenic. Medical search. Frequent questions

Celiacs disease is not a major risk factor for the development of childhood idiopathic thrombocytopenic purpura. (unibas.ch)
Evans syndrome and idiopathic thrombocytopenic purpura in families: Consider autoimmune lymphoproliferative disease. (unibas.ch)
It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura, pemphigus vulgaris, myasthenia gravis and Epstein-Barr virus-positive mucocutaneous ulcers. (wikimili.com)
Helicobacter pylori (H. pylori) are known to be associated with several intestinal and extra-intestinal diseases such as peptic ulcers, mucosa-associated lymphoid tissue lymphoma, gastric cancer and/or idiopathic thrombocytopenic purpura. (ommegaonline.org)
Furthermore, H. pylori is also known to favour the emergence of extra-intestinal diseases such as hepatic encephalopathy [5] and idiopathic thrombocytopenic purpura, sideropenic anemia, and vitamin B 12 deficiency [6] . (ommegaonline.org)
Idiopathic Thrombocytopenic Purpura (ITP) is a hematological disease characterized by decreased number of blood platelets. (bvsalud.org)
Idiopathic Thrombocytopenic Purpura (ITP) is considered one of the most common disorders in children 2,11 , and the incidence of asymptomatic illness is approximately 3-8:100,000 children/year 12 . (bvsalud.org)
Investigators found no evidence for an increased risk for idiopathic thrombocytopenic purpura , multiple sclerosis, GBS, connective tissue disorders (SLE, rheumatoid arthritis, or juvenile arthritis), type 1 diabetes, or autoimmune thyroiditis following vaccination with HPV4. (medscape.com)

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by immune-mediated destruction and impaired production of platelets, with isolated thrombocytopenia. (spandidos-publications.com)
Differential diagnosis of immune thrombocytopenia (ITP), thrombotic thrombocytopenic purpura (TTP), and disseminated intravascular coagulation (DIC). (medscape.com)
What is immune thrombocytopenia purpura? (carenity.co.uk)
Among these, thrombocytopenia is quite often: it has been observed in one third of COVID-19 patients, even up to 57.7% in those with severe disease 2 . (japt.gr)
When severe thrombocytopenia occurs, the clinician must consider the likelihood of immune thrombocytopenic purpura (ITP) 2 . (japt.gr)
Тромботична тромбоцитопенічна пурпура (ТТП) Thrombotic thrombocytopenic purpura (TTP) is an acute, fulminant disorder characterized by thrombocytopenia and microangiopathic hemolytic anemia. (msdmanuals.com)

The complement system is a tightly regulated, cascading protein network that performs multiple roles in homeostasis and disease prevention and is a key component of both the innate and the humoral immune systems. (jrheum.org)
In addition to HUS, the differential diagnosis also includes immune thrombocytopenic purpura (ITP) and disseminated intravascular coagulation (DIC), two entities with very different modes of therapy (see the image below). (medscape.com)
Joly BS, Roose E, Coppo P, Vanhoorelbeke K, Veyradier A. ADAMTS13 conformation is closed in non-immune acquired thrombotic thrombocytopenic purpura of unidentified pathophysiology. (medscape.com)
If you have general, lingering symptoms, you may be suffering from an autoimmune disease -- which means your immune system is attacking healthy tissue. (webmd.com)
One picture is coming into better focus, however, which suggests that an immune-triggered, complement-mediated thrombotic microangiopathy (TMA) is surprisingly common in patients with coronavirus disease 19 (COVID-19). (nature.com)
Augmentation of the platelet counts in the immune thrombocytopenic purpura (ITP) as first demonstrated by Imbach and co-workers, opened the way for the application of IVIG in other autoimmune and inflammatory diseases [1, 9]. (academie-medecine.fr)
IVIG acts at various levels of autoimmune response such as initiation, amplification and effector phase by targeting various soluble and cellular compartments of the immune system. (academie-medecine.fr)
The absence of high quality evidence for basic clinical dilemmas in immune thrombocytopenic purpura (ITP) underlines the need for contemporary guidelines relevant to the local treatment context. (mja.com.au)
Local guidelines are needed to assist clinicians treating immune thrombocytopenic purpura (ITP) in Australia and New Zealand. (mja.com.au)
Posttransfusion reactions, preventive vaccination, and fetal hemolytic disease can contribute to the development of immune hemolytic anemia. (medic-journal.com)
The company was focused on discovering and developing new therapies designed to treat patients by reprogramming the immune system, allowing for long-term remission of immune-related diseases after a short course of therapy. (wikimili.com)
Immune disorders such as multiple sclerosis and rheumatoid arthritis are classified as autoimmune diseases because pathological lesions result from immune attack against the hosts own antigens. (livingwithdiabetes.info)
Other immune disorders, such as asthma and allergies, are merely classed as inflammatory disorders , because the pathology does not involve attack against specific host antigens. (livingwithdiabetes.info)
Although, MS is well characterized in terms of the role played by immune cells, cytokines and CNS pathology, nothing is known about the metabolic alterations that occur during the disease process in circulation. (longdom.org)
Long-Term Risk of Relapse in Immune-Mediated Thrombotic Thrombocytopenic Purpura and the Role of Anti-CD20 Therapy CME / ABIM MOC Lack of early iTTP relapse or treatment failure predictors mandates regular ADAMTS13 monitoring to prevent progression to clinical relapse. (medscape.org)
Do Patients With Immune-Mediated Inflammatory Diseases Have the Same Response to COVID-19 Vaccines? (medscape.org)
Classic immunosuppressants remain the most beneficial and widely used drugs for immune-mediated neuromuscular diseases. (medlink.com)
Most patients with immune-mediated neuromuscular diseases experience improvement of symptoms and quality-of-life measures with appropriate treatment. (medlink.com)
Several specific therapies have emerged as potential treatments for immune-mediated neuromuscular diseases. (medlink.com)
Biological agents have emerged as effective therapies for patients with treatment-resistant immune-mediated neuromuscular diseases. (medlink.com)

To make an accurate diagnosis, the clinician must recognize the similarity between thrombotic thrombocytopenic purpura (TTP) and hemolytic-uremic syndrome (HUS). (medscape.com)
The diagnosis is made upon observation of an abnormally low platelet count , in the absence of other blood work abnormalities, and after exclusion of other possible causes such as ongoing drug therapy or underlying pathology. (carenity.co.uk)
This Multi-Specialty Clinical Referral Laboratory RT DIAGNOSTICS provides precise and accurate tests with an extensive range of testing services to the medical centres to help in the diagnosis and identification of pathology in the test specimens for infectious diseases and also to evaluate the function of organ systems of the patient. (rtdiagnostics.net)
21 years old female who provided us medical report of her endocrinological examination with diagnosis of "Basedow's Hyperthyroidism in autoimmune non-nodular thyroid (Hashimoto's thyroiditis). (doctorsmedicalopinion.com)
Most Parkinson's disease experts now recommend that l-dopa therapy be started as late as possible after diagnosis of Parkinson's disease so as to postpone the day when it no longer works and to limit its many serious adverse effects. (digitalnaturopath.com)
73-year-old male with a diagnosis of Parkinson's disease (PD) since 2001. (doctorsmedicalopinion.com)
This cooperative program should facilitate many advances including the identification of biomarkers for disease risk, disease severity/activity, and clinical outcome and encourage development of new approaches to prevention, diagnosis, and treatment of many rare diseases beyond those being studied. (webharvest.gov)
Warm Autoimmune Hemolytic Anemia: The Foundations of Diagnosis and Management CME / ABIM MOC Join our expert faculty for a discussion on recognizing the signs and symptoms of wAIHA and appropriately managing this patient population. (medscape.org)

Certain medical underlying conditions can alter this Haptoglobin test result namely rheumatoid arthritis, ulcerative colitis, chronic liver disease etc. (rtdiagnostics.net)
Targeted diseases include type 1 diabetes , rheumatoid arthritis , Inflammatory bowel disease (IBD), cancer , chronic and viral diseases . (wikimili.com)
[7] The modified version of TRX1, designated MTRX1011A, is being developed for the treatment of autoimmune diseases, which may include rheumatoid arthritis, cutaneous lupus erythematosus (CLE), multiple sclerosis (MS), and systemic lupus erythematosus (SLE). (wikimili.com)
Rheumatoid Arthritis (RA) Rheumatoid arthritis is a chronic systemic autoimmune disease that primarily involves the joints. (merckmanuals.com)

10 This review aims to provide an assessment of the nature and extent of complement involvement in the underlying pathophysiology of TMA associated with autoimmune diseases that will help to stratify patients for targeted therapy. (jrheum.org)
Epidemiology and pathophysiology of adulthood-onset thrombotic microangiopathy with severe ADAMTS13 deficiency (thrombotic thrombocytopenic purpura): a cross-sectional analysis of the French national registry for thrombotic microangiopathy. (medscape.com)

Abstract Introduction: Dermatoporosis is a chronic cutaneous fragility syndrome, characterized by skin atrophy, purpura and pseudo-cicatrices. (bvsalud.org)

Reports of widespread thromboses and disseminated intravascular coagulation (DIC) in patients with coronavirus disease 19 (COVID-19) have been rapidly increasing in number. (nature.com)

The FDA based approval on clinical studies of patients with liver disease, liver transplant, heart surgery, and TTP. (medscape.com)
ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients. (medscape.com)
In addition to its use in diseases wherein the clinical effectiveness is clearly demonstrated by randomized, double-blind, placebo-controlled trials, IVIG is also used in over 100 other diseases in an off-label manner. (academie-medecine.fr)
General clinical comments relating to the ligand and may not necessarily be specific to the disease in question. (guidetoimmunopharmacology.org)
It was advanced to clinical evaluations is patients with B-cell malignancies, and to determine efficacy against difficult-to-treat autoimmune or inflammatory conditions. (guidetoimmunopharmacology.org)
These pre-clinical candidates may be developed for the treatment of cancer and viral diseases. (wikimili.com)
While in a clinical remission, he was diagnosed with Crohn's disease and initially treated with adalimumab. (elsevierpure.com)
The patient was diagnosed with "suspect motor neuron disease" and was treated with IVIG cycles with slight initial improvement, but later lack of response and worsening of the clinical condition. (doctorsmedicalopinion.com)
On February 27, 2003, ORD in response to the Rare Diseases Act of 2002, P.L. 107-280, released a Request for Applications (RFA) for a Rare Diseases Clinical Research Network together with the National Center for Research Resources (NCRR)/General Clinical Research Consortium (GCRC) Program and in collaboration with other NIH Institutes. (webharvest.gov)
We propose to establish a Rare Disease Clinical Research Consortium (RDCRC) at the Children's National Medical Center (CNMC) in Washington, D.C. The RDCRC will draw support from both the Pediatric General Clinical Research Center at CNMC/Georgetown University Medical Center (GUMC) as well as its Mental Retardation and Developmental Disabilities Research Center (MRDDRC). (webharvest.gov)
This report summarizes the epidemiology of human papillomavirus (HPV) and associated diseases, describes the licensed HPV vaccines, provides updated data from clinical trials and postlicensure safety studies, and compiles recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) for use of HPV vaccines. (cdc.gov)

Your first symptoms of an autoimmune disease may be general, such as fatigue , low-grade fever, and difficulty concentrating, making autoimmune diseases difficult to diagnose at first. (webmd.com)
As the disease develops -- or more than one, as Rose points out -- vague symptoms start to appear, such as joint and muscle pain (very common), general muscle weakness, possible rashes or low-grade fever, trouble concentrating, or weight loss. (webmd.com)
SLE is a complex autoimmune disease that is characterised by inflammation of various connective tissues, and symptoms include dermatitis, arthritis, inflammation of the kidneys (glomerulonephritis), vasculitis, inflammation of the tissue surrounding the heart, and seizures. (guidetoimmunopharmacology.org)
Children who continue to be severely thrombocytopenic with significant bleeding symptoms are very rare - refer to a specialist centre for management. (scottishpaeds.org.uk)
Although l-dopa medications can bring significant relief from Parkinson's disease symptoms they become less effective with time. (digitalnaturopath.com)
During the preceding six weeks the girl had no signs or symptoms of infectious diseases nor she had assumed any drugs. (biomedcentral.com)

Current treatment options are discussed for the most frequent of these diseases: inflammatory neuropathies, myasthenia gravis, and inflammatory myopathies. (medlink.com)

what ensues after registering these complaints may be an odyssey to pinpoint which of the almost 60 different autoimmune disorders you might have, all of which affect the body differently. (webmd.com)
Although autoimmune disorders can make life miserable, they usually are chronic and not fatal, Shomon says. (webmd.com)
In participants with suspected MDS and prior to registration with subsequent bone marrow evaluation, alternative causes for the cytopenias should be considered (e.g., internal bleeding, autoimmune cytopenias, thyroid disorders, other causes of anemia etc. (ecog-acrin.org)
Infection with H. pylori plays a crucial role in the pathogenesis of several gastric disorders such as peptic ulcer disease, mucosa-associated lymphoid tissue lymphoma and gastric cancer. (ommegaonline.org)
Additionally, H. pylori have also been considered as a potential trigger of autoimmune disorders [7] . (ommegaonline.org)
Other studies have also indicated that detection of H. pylori in liver tissue was associated with a higher incidence and progression of liver diseases such as Hepatocellular Carcinoma (HCC), hepatitis C-infection or autoimmune liver disorders [10] . (ommegaonline.org)
Purpura is a disease included in the large group of hemorrhagic disorders and is distinguished by cutaneous hemorrhage and blood loss from mucous membranes and internal organs, which is always related to vascular or platelet alterations 2 . (bvsalud.org)
Are Maternal Autoimmune Disorders Linked to Mental Illness in Children? (medscape.org)
The neuromuscular disorders treated with immunotherapies encompass a large and heterogeneous group of diseases, including the inflammatory neuropathies, neuromuscular junction diseases, and inflammatory myopathies. (medlink.com)
To address concerns over news reports or published case series of autoimmune disorders appearing after HPV immunization, I will focus on studies related to the association between HPV vaccine and autoimmune disorders in this review. (medscape.com)

The formation of antibodies agglutinating erythrocytes is possible with hemoblastosis (acute leukemia, chronic lymphocytic leukemia, lymphogranulomatosis ), autoimmune pathology (SLE, ulcerative colitis), infectious diseases ( infectious mononucleosis , toxoplasmosis , syphilis , viral pneumonia). (medic-journal.com)
IBD) is a comprehensive term covering two different but overlapping conditions: Crohn's disease and ulcerative colitis. (dummies.com)

Rituximab , sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. (wikimili.com)

Caplacizumab (Cablivi), a nanobody that targets von Willebrand factor (vWF), was approved by the FDA in 2019 for treatment of acquired thrombotic thrombocytopenic purpura (aTTP) in combination with plasma exchange and immunosuppressive therapy. (medscape.com)
Autoimmune thrombotic thrombocytopenic purpura (aTTP) is caused by autoantibodies to the von Willebrand Factor cleaving enzyme, ADAMTS13. (elsevierpure.com)

To our knowledge, this is the first description of a pediatric patient with Henoch-Schönlein purpura occurring in association with vaccination against COVID-19. (biomedcentral.com)

Ferrari S, Mudde GC, Rieger M, Veyradier A, Kremer Hovinga JA, Scheiflinger F. IgG-subclass distribution of anti-ADAMTS13 antibodies in patients with acquired thrombotic thrombocytopenic purpura. (medscape.com)
21-Hydroxylase antibodies are markers of autoimmune Addison disease, which may manifest alone or as part of type I or type II polyglandular autoimmune syndrome. (medscape.com)
A test result of 21-hydroxylase antibodies at 1 U/mL or higher indicates the presence of adrenal autoantibodies, which is consistent with Addison disease. (medscape.com)
Healthy subjects rarely have antibodies against other endocrine glands, but this is common in patients with autoimmune adrenal insufficiency. (medscape.com)
Currently, IPT is considered an autoimmune disease and its etiology is related to immunological mechanisms such as antibodies and antiplatelet immunoglobulin in the blood 16 . (bvsalud.org)
New therapies used in these diseases, including biological agents (monoclonal antibodies or recombinant proteins), are also reviewed. (medlink.com)

7 - 9 A TMA is called "primary" when a genetic or acquired defect in a complement protein is identified (as in atypical hemolytic uremic syndrome [aHUS]) or "secondary" when occurring in the context of another disease process or factor such as infection, autoimmune disease, malignancy, or drugs. (jrheum.org)
Thrombotic thrombocytopenic purpura and the atypical hemolytic uremic syndrome: an update. (medscape.com)

Her medical history is unremarkable except for celiac disease which is treated with a gluten-free diet. (doctorsmedicalopinion.com)
Here you see conditions such as irritable bowel syndrome (IBS), ischemic bowel, inflammatory bowel disease (IBD), celiac disease, and diverticulitis. (dummies.com)

Systemic lupus erythematosus (SLE) is a chronic autoimmune connective tissue disorder, with a heterogeneous presentation. (lww.com)

These microthrombi strings trigger disseminated intravascular microthrombosis (DIT), which is the underlying pathology of endotheliopathy-associated vascular microthrombotic disease (EA-VMTD). (biomedcentral.com)

Autoimmune Hepatitis/cholangitis In Patient With Crohn's Disease. (doctorsmedicalopinion.com)

Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder characterized by clotting in small blood vessels (thromboses), resulting in a low platelet count. (medscape.com)
The pathology of the disorder involves destruction of autoantibody-presenting platelets by the spleen and liver, and insufficient hematopoiesis of megakaryocytes is also observed because of the relative shortage of the megakaryocyte hematopoietic factor thrombopoietin. (biomedcentral.com)
The disorder was recognized as early as the Middle Ages, with the 12th-century physician Rogerius being the first to apply the term lupus to the classic malar rash, and in 1872, Moric Kaposi first recognized the systemic nature of the disease. (lww.com)
To summarize the breadth of data exploring the relationship between major depressive disorder (MDD) and both the incidence and the disease course of a range of comorbidities. (psychiatrist.com)
Systemic lupus erythematosus is a chronic, multisystem, inflammatory disorder of autoimmune etiology, occurring predominantly in young women. (merckmanuals.com)
Acquired hemophilia A (AHA) is a rare autoimmune bleeding disorder caused by circulating autoantibodies (inhibitor) directed against coagulation factor VIII (FVIII). (journalmc.org)

Beyond the platelet count, the decision to treat is affected by individual bleeding risk, disease stage, side effects of treatment, concomitant medications, and patient preference. (mja.com.au)

Pemphigus is a potentially fatal disease, associated with a mortality rate as high as 90-100 percent when untreated [ 1 ]. (cdlib.org)
Prednisone in doses varying from 40 to 400 mg has been used in the treatment of pemphigus, the higher doses being required for 5-10 weeks for disease control [ 2 ]. (cdlib.org)

3 Males and patients with later age of onset tend to have more severe disease and poorer prognosis. (lww.com)
Treatment of severe, ongoing, active disease requires corticosteroids and immunosuppressants. (merckmanuals.com)
We report a 39-year-old single female who presented to emergency department with sudden onset gross hematuria 10 days following her first dose of Pfizer-BioNTech severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA (coronavirus disease 2019 (COVID-19)) vaccine. (journalmc.org)

The presence of adrenal cortex autoantibodies in the serum is associated with Addison disease. (medscape.com)

Drug-induced thrombotic thrombocytopenic purpura: A systematic review and review of European and North American pharmacovigilance data. (medscape.com)

The patient reported that purpura and ecchymoses had appeared two days prior to presentation. (spandidos-publications.com)
43 years old patient without any notable pathologies in anamnesis. (doctorsmedicalopinion.com)
Based on these results, H. pylori do not appear to have a significant impact on the progression of liver disease in our patient cohort. (ommegaonline.org)

The 62-year-old male was admitted to the Hematology Clinic with generalized purpura and atraumatic ecchymoses. (spandidos-publications.com)

Besides, viral infections are known to induce autoimmune phenomena 3 . (japt.gr)

Common manifestations may include arthralgias and arthritis, Raynaud syndrome, malar and other rashes, pleuritis or pericarditis, renal or central nervous system involvement, and autoimmune cytopenias. (merckmanuals.com)

Aplastic anemia and concomitant autoimmune diseases. (unibas.ch)

Children, unmarried individuals, those who had not completed their families, pregnant or lactating women, patients older than 65 years, and those with hepatic disease were excluded. (cdlib.org)

An increasing number of immunotherapies are being used to treat the heterogeneous group of neuromuscular diseases believed to have an autoimmune pathogenesis. (medlink.com)

This review aims to provide an assessment of the nature and extent of complement involvement in TMA associated with autoimmune diseases such as systemic lupus erythematosus, antiphospholipid syndrome, and scleroderma renal crisis. (jrheum.org)

1 - 3 Acute kidney injury is a common prominent feature of the disease, owing to the susceptibility of the glomerular circulation to endothelial damage. (jrheum.org)
CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)

See bruising - beware non-accidental injury (NAI) and meningococcal disease: children with infection usually have other features and non-accidental injury does not present with generalized purpura. (scottishpaeds.org.uk)
HIV disease (symptomatic HIV infection) appears as the CD4 count progressively declines over a long incubation period, which may extend over 5 to 15 years or more. (intelligentdental.com)
One study found an association between H. Pylori seropositivity and hepatocyte ballooning, suggesting that H. pylori infection may play a role in the progression of non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis [9] . (ommegaonline.org)
Infectious Disease Specialist Perspectives on CMV Management in Transplant Patients: New Data and New Options CME / ABIM MOC / CE How should you best manage cytomegalovirus (CMV) infection in patients post-transplant? (medscape.org)

In 2011, Chao and colleagues [ 1 ] at the Kaiser Permanente Vaccine Study Center in Oakland, California, evaluated 189,629 women of all ages who had received at least one dose of the quadrivalent HPV vaccine (HPV4) between 2006 and 2008 and compared the incidence of autoimmune diseases in these women vs the incidence in women who hadn't received the vaccine. (medscape.com)
Again, investigators found no differences in the incidence of such autoimmune diseases as GBS and multiple sclerosis in vaccinated people compared with background rates of these diseases. (medscape.com)

The prevalence of ITP in non-Hodgkin's lymphoma patients is lower compared to autoimmune hemolytic anemia, occurring in only up to 1.8% of cases ( 3 ). (spandidos-publications.com)
His past medical history comprised several comorbidities, including heart failure, atrial fibrillation, mechanical aortic valve, implanted pacemaker, chronic obstructive pulmonary disease (COPD), dyslipidemia, chronic kidney disease and anemia of chronic disease. (japt.gr)
Hemolytic anemia is a pathology of red blood cells, the hallmark of which is the accelerated destruction of red blood cells with the release of an increased amount of indirect bilirubin. (medic-journal.com)
With the autoimmune mechanism of anemia, the formation of anti-erythrocyte AT (heat, cold) occurs, which cause enzymatic lysis of the erythrocyte membrane. (medic-journal.com)

Despite the fact that IVIG is used for more than two decades in the treatment of a number of autoimmune and inflammatory conditions, the underlying molecular mechanisms that account for its beneficial effect have not been completely elucidated. (academie-medecine.fr)

For this group of diseases, a combination of anemic syndrome, jaundice and an increase in the size of the spleen is typical. (medic-journal.com)
these together comprise type I or type II polyglandular autoimmune syndrome. (medscape.com)
AIDS-like syndrome: AIDS-like disease (illness) (syndrome) ARC AIDS-related complex Pre-AIDS AIDS-related conditions Prodromal-AIDS 3. (cdc.gov)

Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the CNS. (longdom.org)
Multiple sclerosis (MS) patients may also be at risk of the disease and its complications depending on the medication they are taking. (drnasermoghadasi.com)
Multiple sclerosis (MS) is recognized as a demyelinating disease of the central nervous system through autoimmune involvement of the brain and spinal cord (1-4). (drnasermoghadasi.com)

Moreover, her familiar medical history was unremarkable: no autoimmune or chronic pathologies were reported in her relatives. (biomedcentral.com)

Stem cells can help correct autoimmune diseases and some congenital defects. (nursingdons.com)

Treatment is supportive as the disease course is generally benign and self-limited [ 1 ]. (biomedcentral.com)

2 , 4 - 6 Early recognition is important because TMA is associated with significant mortality and morbidity, including end-stage kidney disease, although prompt initiation of supportive and specific management can transform disease outcomes. (jrheum.org)
The National Institute of Diabetes and Digestive and Kidney Diseases has played an important role in developing artificial pancreas technology. (livingwithdiabetes.info)
Хронічна хвороба нирок Chronic kidney disease (CKD) is long-standing, progressive deterioration of renal function. (msdmanuals.com)

In the United States, autoimmune destruction of the adrenal cortex most commonly causes chronic primary adrenal insufficiency (Addison disease). (medscape.com)

Even with a genetic tendency, a person may not develop an autoimmune disease without an environmental influence to set it off. (webmd.com)
Genetic factors may also be involved, such as a family history of autoimmune conditions. (livingwithdiabetes.info)
HSP is a complex disease, caused by several genetic and environmental factors. (biomedcentral.com)

Anatomy13

Organisms9

Diseases61

Chemicals and Drugs57

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Phenomena and Processes16

Disciplines and Occupations4

Information Science4

Named Groups1

Health Care8

Geographicals1

Idiopathic thrombo8

Thrombocytopenia6

Immune20

Diagnosis8

Rheumatoid4

Pathophysiology2

Abstract1

Disseminated intravascul1

Clinical11

Symptoms6

Myasthenia gravis1

Disorders10

Ulcerative colitis2

Certain autoimmune diseases1

ATTP2

Pediatric1

Antibodies6

Hemolytic uremic s2

Celiac disease2

Connective1

Vascular1

Hepatitis1

Disorder6

Platelet1

Pemphigus2

Severe3

Autoantibodies1

Systematic review1

Patient3

Hematology1

Phenomena1

Cytopenias1

Aplastic anemia1

Hepatic1

Pathogenesis1

Lupus1

Acute2

Infection4

Incidence2

Anemia4

Inflammatory conditions1

Syndrome3

Multiple sclerosis3

Unremarkable1

Congenital1

Benign1

Kidney3

Adrenal cortex1

Genetic3