• There is no consensus definition of the term pathologic myopia. (eyerounds.org)
  • Many studies define high myopia (HM) as -5.00 to -8.00 diopters axial myopia or >26.0 mm to >26.5 mm axial length and pathologic myopia (PM) as HM in addition to lesions or degenerative fundus changes that result in decreased best corrected visual acuity. (eyerounds.org)
  • Acquired optic nerve and peripapillary pits in pathologic myopia. (surajeyeinstitute.org)
  • VISUDYNE, an injectable photosensitizer drug indicated for the treatment of patients with predominantly classic subfoveal choroidal neovascularization due to AMD, pathologic myopia, or presumed ocular histoplasmosis is activated through use of a photodynamic laser via direct laser excitation. (optometrytimes.com)
  • The most common defect seen is an arcuate scotoma, although any type of visual defect can be seen, including altitudinal defects, nasal or temporal steps, paracentral scotomas, enlarged blind spots, or generalized depression. (surajeyeinstitute.org)
  • In exudative AMD , abnormal choroidal vessels/capillaries (pathologic choroidal neovascular membranes) develop under the macula, leak fluid and blood, and, ultimately, cause a central fibrous sub-retinal scar, with destruction of the photoreceptors and retinal pigment epithelium. (cehjournal.org)
  • En face OCT reflectance images which accompany OCTA studies offer a glimpse of the macrophage-like cellular activity above the retinal surface which responds to systemically instigated vascular events below. (stanford.edu)
  • Given its high degree of reproducibility, SD-OCT is an invaluable technique for characterizing pathologic features of the retina, including the retinal pigment epithelium, and in assessing disease activity and therapeutic response. (reviewofophthalmology.com)
  • The second mechanism is associated with a serous detachment of the retina, which usually manifests as a central scotoma or other central visual field changes. (surajeyeinstitute.org)
  • It has a fundamental role in the development, structure, and function of the retina, although it also is a pathologic component in the various vitreoretinal disorders, most notably in macular holes. (hindawi.com)
  • Signs and symptoms of acute optic neuropathy include painless loss of vision which may affect either one or both eyes, reduced visual acuity, reduced color vision, relative afferent pupillary defect, central scotoma, swollen optic disc, macular edema, or retrobulbar pain. (wikipedia.org)
  • Patients who develop atrophic AMD may notice a scotoma (blind spot), which slowly enlarges over months or years before becoming stable. (cehjournal.org)
  • See also blind spot (scotoma), or a root + -icalis of, relating to, or resembling] pathological fire-setting n. (riversideortho.com)
  • ABCA4 mutations also can lead to cone-rod dystrophy (CRD) [ 5 - 7 ], a more severe form of retinal degeneration causing reduced central vision and progressive reduction of general cone function with severe central and paracentral scotomas and reduced color vision. (molvis.org)
  • Signs and symptoms of acute optic neuropathy include painless loss of vision which may affect either one or both eyes, reduced visual acuity, reduced color vision, relative afferent pupillary defect, central scotoma, swollen optic disc, macular edema, or retrobulbar pain. (wikipedia.org)
  • Characteristic findings correlated well with pathologic results and postulated toxicity. (medscape.com)
  • Characteristic seizures include myoclonic and occipital lobe seizures with visual hallucinations, scotomata, and photoconvulsions. (nih.gov)
  • A, A patient with -16 diopter myopia developed a small scotoma near the center of the visual field. (aao.org)
  • Early manifestations of CNV in pathologic myopia include decreased or distorted vision. (aao.org)