Hereditary Breast and Ovarian Cancer SyndromeOvarian NeoplasmsGenes, BRCA1BRCA2 ProteinBRCA1 ProteinGenes, BRCA2Neoplastic Syndromes, HereditaryGenetic TestingPTEN PhosphohydrolaseGerm-Line MutationGenetic CounselingSyndromeBreast NeoplasmsPedigreeGenes, DominantGenetic Predisposition to DiseaseMutationBreastHeterozygotePolycystic Kidney, Autosomal DominantDNA Mutational AnalysisNeoplasm ProteinsNeoplasms, Glandular and EpithelialFounder EffectFamily HealthBreast Neoplasms, MaleGenetic LinkageAge of OnsetHamartoma Syndrome, MultipleGene Expression Regulation, NeoplasticColorectal Neoplasms, Hereditary NonpolyposisCell Line, Tumorvon Hippel-Lindau DiseaseExonsRisk FactorsDNA, NeoplasmCarcinoma, Ductal, BreastPhenotypeMastectomyGenotypeBreast Diseases