Phosphorus tribromide is a colourless liquid with the formula PBr3. (wikipedia.org)
Phosphorus tribromide is also generated in situ from red phosphorus and bromine. (wikipedia.org)
Phosphorus tribromide, like PCl3 and PF3, has both properties of a Lewis base and a Lewis acid. (wikipedia.org)
For example, with a Lewis acid such as boron tribromide it forms stable 1 :1 adducts such as Br3B · PBr3. (wikipedia.org)
In a similar reaction, PBr3 also converts carboxylic acids to acyl bromides: PBr3 + 3 RCO2H → 3 RCOBr + HP(O)(OH)2 The main use for phosphorus tribromide is for conversion of primary or secondary alcohols to alkyl bromides, as described above. (wikipedia.org)
The overall process can be represented as On a commercial scale, phosphorus tribromide is used in the manufacture of pharmaceuticals such as alprazolam, methohexital and fenoprofen. (wikipedia.org)
Phosphorus tribromide is used for doping in microelectronics. (wikipedia.org)
E280 (Propionic acid) undergoes the Hell-Volhard-Zelinsky reaction that involves α-halogenation of a carboxylic acid with bromine, catalysed by phosphorus tribromide, in this case to form 2-bromopropanoic acid, CH3CHBrCOOH. (atamanchemicals.com)
Alkyl bromides1
Alcohols get converted into alkyl bromides on treatment with PBr3. (topperlearning.com)
Alcohols2
An important reaction of PBr3 is with alcohols, where it replaces an OH group with a bromine atom to produce an alkyl bromide. (wikipedia.org)
PBr3 evolves corrosive HBr, which is toxic, and reacts violently with water and alcohols. (wikipedia.org)
Carboxylic acid1
Initially PBr3 reacts with the carboxylic acid to form the acyl bromide, which is more reactive towards bromination. (wikipedia.org)
Trihalides1
Why is the same not true for phosphorus trihalides as backbonding exists in them too? (popesports.es)
PBr3 usually gives higher yields than hydrobromic acid, and it avoids problems of carbocation rearrangement- for example even neopentyl bromide can be made from the alcohol in 60% yield. (wikipedia.org)
Nitrogen1
The results showed than an excellent removal of nutrients (nitrogen and phosphorus) from the agricultural wastewater, which was achieved mostly in the first photobioreactor (PBR). (incover-project.eu)
Reaction1
An excess of phosphorus is used in order to prevent formation of PBr5: P4 + 6 Br2 → 4 PBr3 Because the reaction is highly exothermic, it is often conducted in the presence of a diluent such as PBr3. (wikipedia.org)
Atom1
6. It is six in total, where three valence electrons are needed by the phosphorus atom and one, each by three fluorine atoms. (popesports.es)
Lewis1
At the same time PBr3 can react as an electrophile or Lewis acid in many of its reactions, for example with amines. (wikipedia.org)
Forms1
Phosphorus forms individual P4 molecules. (answers.com)
OXYCHLORIDE2
Phosphorus oxychloride (POCl 3 ) is a useful reagent for cleanly performing elimination reactions on alcohols. (esterlium.net)
So a compromise is to use the reagent phosphorus oxychloride (POCl 3 ), a derivative of phosphoric acid. (esterlium.net)