OsteomalaciaDialysisPhosphateHyperparathyroidismHemodialysisSacral insufficiency fractureCortical NecrosisProteinuriaDysfunctionAcidosisFractureStage renal diseaseAdrenal InsufficiencyDiseaseOsteoporosisBiopsyCarcinomaImpairmentHypertensionDiseasesHypophosphatemiaSecondaryProgressionFailureSodiumNonspecificDisordersDisturbancesAbnormalitiesBilateralElectrolyteBoneHomeostasisPatients
Osteomalacia4
- Renal osteodystrophy causes rachitic and some osteomalacic changes in the child and osteomalacia and secondary hyperparathyroidism in adults. (medscape.com)
- The histopathologic findings of renal osteodystrophy are commonly used to further classify the condition into high bone turnover states, such as osteitis fibrosa and hyperparathyroidism, and low bone turnover states, such as adynamic bone disease or heavy metal-induced osteomalacia. (medscape.com)
- Adefovir dipivoxil (ADV)-induced renal tubular dysfunction and hypophosphatemic osteomalacia (HO) have been given great consideration in the past few years. (biomedcentral.com)
- Various studies have reported that adefovir dipivoxil (ADV) can cause proximal renal tubular complex dysfunction, hypophosphatemic osteomalacia (HO) and even Fanconi syndrome since it was first used in the long-term treatment of chronic hepatitis B in 2002 [ 3 ]. (biomedcentral.com)
Dialysis6
- Current areas of investigation include the noradrenergic control of blood pressure in kidney disease, mechanisms and management of vascular calcifications in dialysis patients, detection and management of cardiovascular disease in dialysis patients and prevention of progressive renal disease in African-Americans. (usc.edu)
- Administered orally and intravenously, calcitriol is commonly used as a medication in the treatment of secondary hyperparathyroidism and resultant metabolic bone disease, hypocalcemia in patients undergoing chronic renal dialysis, and osteoporosis. (drugbank.com)
- Used to treat vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. (drugbank.com)
- FOSRENOL is the first commercially available non-calcium, non-resin phosphate binder in Japan and is used in the control of hyperphosphataemia in chronic renal failure patients on dialysis. (salesandmarketingnetwork.com)
- The patient had been on intermittent hemodialysis for 18 years after first presenting acutely in the year 2000 with renal failure and pulmonary edema requiring urgent dialysis. (ochsnerjournal.org)
- In these cases, the loss of renal function is already very significant, which makes treatment difficult and may require dialysis sessions. (blimpt.com)
Phosphate4
- Renal production of calcitriol is stimulated in response to PTH, low calcium and low phosphate 4 . (drugbank.com)
- Calcitriol plays a role in plasma calcium regulation in concert with parathyroid hormone (PTH) by enhancing absorption of dietary calcium and phosphate from the gastrointestinal tract, promoting renal tubular reabsorption of calcium in the kidneys, and stimulating the release of calcium stores from the skeletal system. (drugbank.com)
- In addition, a renal tubular defect that reduces reabsorption may alter phosphate metabolism. (medscape.com)
- Patients are also at risk of other nutritional problems including disturbed calcium and phosphate status, which stems from insufficiency of serum 25-hydroxy vitamin D. Anaemia is also an issue for patients with CKD and is one of the factors which impinges significantly on quality of life and cardiovascular complications. (nhdmag.co.uk)
Hyperparathyroidism2
- The radiological and laboratory criteria in addition to the history and other clinical findings can differentiate it from similar conditions affecting the SIJ, such as Ankylosing Spondylitis, Seronegative Spondyloarthropathies, Sacroilitis, Primary Hyperparathyroidism, Paget's disease, Renal Osteodystrophy, Lymphoma and Bone Secondaries. (clinicalmaze.com)
- Hungry bone syndrome is hypocalcemia after surgery for hyperparathyroidism (HPT) in patients with severe prolonged disease (secondary or tertiary HPT in renal failure). (teachmemedicine.org)
Hemodialysis2
- Musculoskeletal problems are still one of the important determinants of the life quality in patients with chronic renal failure (CRF), especially in patients undergoing hemodialysis treatment [1,2]. (rheumres.org)
- This report details a rare and extreme manifestation of chronic kidney disease mineral and bone disorder in a patient on long-term hemodialysis for end-stage renal failure. (ochsnerjournal.org)
Sacral insufficiency fracture1
- One of the studies reported mortality within the three years after the occurrence of sacral insufficiency fracture as 25.5% (6) . (jtss.org)
Cortical Necrosis1
- [4] Severe cases develop acute cortical necrosis affecting most cells in the renal cortex. (marlerblog.com)
Proteinuria1
- For the arterial calcification, vitamin D supplement provides adjunctive role in regressing proteinuria, reverse renal osteodystrophy, and restoring calcification inhibitors. (tmu.edu.tw)
Dysfunction3
- Antepsin should only be used with caution in patients with renal dysfunction, due to the possibility of increased aluminium absorption. (com.bd)
- The clinical picture, laboratory and radiograph alterations are important clues for those patients and are usually characterized by polyarthralgia, renal tubular dysfunction and mineralization defects. (biomedcentral.com)
- First, a unified definition of ADV-related renal dysfunction has not yet been identified. (biomedcentral.com)
Acidosis2
- Notwithstanding this questionable role of bone mineral in systemic acid-base equilibrium, not only in CKD but even more in the absence of renal impairment, it is postulated that, in healthy individuals, foods, particularly those containing animal protein, would induce 'latent' acidosis and result, in the long run, in osteoporosis. (cambridge.org)
- The impact of CKD on growth is multifactorial and includes prior corticosteroid therapy, chronic metabolic acidosis, anorexia, inadequate nutrient and caloric intake, hyposthenuria (urine with low specific gravity due to kidney's inability to concentrate the urine), sodium depletion, hormonal imbalance, growth hormone resistance, hypothyroidism, and renal osteodystrophy (a disorder of bone remodeling). (medscape.com)
Fracture2
- The most common complication of renal osteodystrophy is fracture, which may be insufficiency fractures through osteomalacic bone or pathologic fractures through brown tumors or amyloid deposits. (medscape.com)
- All of these changes in the structure of the bone, which are seen both in the senile osteoporosis and post-menopausal osteoporosis, cause an increase in the fracture risk even during the regular activity and these fractures are defined as insufficiency fractures. (jtss.org)
Stage renal disease3
- Chronic renal insufficiency (CRI), which may include end stage renal disease, is defined as a persistent elevation of serum creatinine and/or urea. (pfizerpro.co.uk)
- The aim of the present study was to estimate the serum levels of 1.25- dihydroksycho-lekalciferol (1.25(OH)2D3) and 25- hydroksycholekalciferol (25(OH)D3) in correlation with parathyroidfunction and mineral bone density in children with end-stage renal disease. (pdfdrug.com)
- Assadi F. Lack of NPHP2 mutations in a newborn infant with Joubert syndrome-related disorder presenting as end-stage renal disease. (rush.edu)
Adrenal Insufficiency2
- Autoimmune hypoparathyroidism is seen as an isolated defect or as part of polyglandular autoimmune syndrome type I in association with adrenal insufficiency and mucocutaneous candidiasis. (teachmemedicine.org)
- Adrenal insufficiency in a woman secondary to standard-dose inhaled fluticasone propionate therapy. (mainehealth.org)
Disease5
- The faculty have a variety of clinical protocols dealing with diabetic nephropathy, bone disease, progression of kidney disease, kidney transplantation, vitamin deficiency in chronic kidney disease, end-stage renal disease, transplantation and nutrition in patients with acute kidney injury. (usc.edu)
- Chronic kidney disease (CKD) is long-standing, progressive deterioration of renal function. (msdmanuals.com)
- Chronic kidney disease (CKD) is initially described as diminished renal reserve or renal insufficiency, which may progress to renal failure (end-stage kidney disease). (msdmanuals.com)
- Functional KIDNEY FAILURE in patients with liver disease, usually LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL), and in the absence of intrinsic renal disease or kidney abnormality. (rush.edu)
- The nutritional management of people who have kidney disease is important to consider, especially in terms of slowing the rate of renal deterioration and controlling the development and progression of co-morbidities. (nhdmag.co.uk)
Osteoporosis1
- My research focuses on gravitational physiology, etiology and treatment of osteoporosis, osteoimmunology, and renal osteodystrophy. (oregonstate.edu)
Biopsy1
- Diagnosis is based on laboratory testing of renal function, sometimes followed by renal biopsy. (msdmanuals.com)
Carcinoma1
- De novo multifocal renal cell carcinoma in the renal allograft. (rush.edu)
Impairment2
- The progression of CKD is classified as stages 1-5, with stage 1 representing the very early phase with mild impairment of glomerular filtration rate, and stage 5 representing full renal failure. (nhdmag.co.uk)
- In patients with severe or chronic renal impairment, Antepsin should be used with extreme caution and only for short-term treatment. (com.bd)
Hypertension1
- in which hypertension and type 2 diabetes are present, is a large and growing cause of renal damage. (msdmanuals.com)
Diseases2
- As seen in other kidney diseases, in STEC-HUS patients the progression to CKD is the consequence of renal mass reduction due to the loss of nephrons during the acute stage. (marlerblog.com)
- It has a number of consequences including cardiovascular diseases, osteodystrophy, pericarditis and anaemia. (nhdmag.co.uk)
Hypophosphatemia1
- This article reviews similar clinical conditions and revealed that advanced states of malignancy seemed to be associated with the development of renal wasting hypophosphatemia, especially in lung cancer and prostate cancer. (bvsalud.org)
Secondary1
- Coronal T1-weighted MRI of the knee in a renal transplant patient on steroids reveals serpentine hypointensity in the metaphyseal and subchondral regions (black arrows) with secondary chondral collapse of the lateral femoral condyle (white arrow). (medscape.com)
Progression1
- Progression to renal failure and deafness in females is less likely. (entokey.com)
Failure7
- Lateral radiograph of the leg in a child with chronic renal failure reveals anterior bowing of the distal tibia. (medscape.com)
- The severity of growth retardation is directly related to the age of onset of renal failure-the earlier the onset, the more severe the growth disturbance. (medscape.com)
- A 56-year-old indigenous Australian male with end-stage renal failure presented to the emergency department of a metropolitan Australian academic hospital complaining of lethargy for several weeks. (ochsnerjournal.org)
- Patients often progress to end-stage renal failure and high-tone deafness by age 40. (entokey.com)
- Alport syndrome accounts for approximately 2.1% of pediatric patients with end-stage renal failure. (entokey.com)
- 90% of male patients with X-linked Alport syndrome develop renal failure and are deaf by age 40. (entokey.com)
- Because of this characteristic, chronic renal failure is often diagnosed late. (blimpt.com)
Sodium1
- It is characterized by intense renal vasculature constriction, reduced renal blood flow, OLIGURIA, and sodium retention. (rush.edu)
Nonspecific2
- Renal osteodystrophy may also present with nonspecific signs and symptoms, including weakness, bone pain, and skeletal deformity. (medscape.com)
- Nonspecific renal histology. (entokey.com)
Disorders2
- Renal osteodystrophy is a term that covers a complex of musculoskeletal disorders in CRF. (rheumres.org)
- All patients who had any musculoskeletal disorders before renal involvement were excluded. (rheumres.org)
Disturbances1
- S³owa kluczowe: przewlek³a niewydolnoœæ nerek, kalcydiol, kalcitriol, parathormon Abstract: The active vitamin D metabolite production disturbances in progressive renal insufficiency lead torenal osteodystrophy. (pdfdrug.com)
Abnormalities1
- Initially, as renal tissue loses function, there are few noticeable abnormalities because the remaining tissue increases its performance (renal functional adaptation). (msdmanuals.com)
Bilateral2
- Milkman syndrome is a condition in which the patient experiences multiple insufficiency fractures that are often bilateral and symmetric. (medscape.com)
- He had a known provisional diagnosis of CKD-MBD, having previously had multiple vertebral insufficiency fractures and bilateral atraumatic femoral neck fractures for which he had undergone simultaneous hip hemiarthroplasty in 2016. (ochsnerjournal.org)
Electrolyte1
- Decreased renal function interferes with the kidneys' ability to maintain fluid and electrolyte homeostasis. (msdmanuals.com)
Bone1
- Consideration that the renal and ureteric infection could spread to the nutrient foramina in the iliac bone leading to ischaemia has been a factor of the work of Szabados (1947) and according to their findings, ischaemic iliac bone necrosis is the main contributing hypothesis for OCI, in a way similar to that of early hip avascular necrosis. (clinicalmaze.com)
Homeostasis1
- In a historical perspective, the present review dissects out speculation from experimental facts and emphasises the essential role of the renal tubule in systemic acid-base and Ca homeostasis. (cambridge.org)
Patients3
- Shire is proud of its ongoing commitment to renal medicine as it makes FOSRENOL available to an increasing number of patients around the world. (salesandmarketingnetwork.com)
- Effect of stage-based education provided by dedicated dietitians on hyperphospataemic haemodialysis patients: results from the Nutrition Education for Management of Osteodystrophy randomised controlled trial. (nhdmag.co.uk)
- Implementation of an early renal tubular injury index is recommended for patients with higher risk, which would prevent further renal injury. (biomedcentral.com)