OrganismsDiseases
ThogotovirusIsavirusOrthomyxoviridaeOrthomyxoviridae InfectionsSalmo salarSalmonFish Diseases
ThogotovirusMiceVirologyViral infectionFlaviviridaeVaccinesImmunityDiseasesFamilyAntibodiesPathogensDiseaseUpon influenza A virDescriptorPrevent influenza infectionVaccinationBourbonAntigenHumansSpecificityPandemicClinicalRespiratory syncyPneumococcalInnateBacterialReplicationH5N1VirulentVirus infectionBirdsSymptomsInductionDepletion
Thogotovirus2
  • Dhori virus (DHOV) is a species of the genus Thogotovirus and a member of the family Orthomyxoviridae. (wikipedia.org)
  • Murine models of Dhori virus infection, which belongs to the Thogotovirus genus, demonstrate an exaggerated cytokine response, including tumor necrosis factor, interleukin-1, interleukin-6, interleukin-10, macrophage inflammatory protein 1, monocyte chemoattractant protein (MCP)-1, and interferon (IFN). (medscape.com)
Mice2
  • DHOV is lethal to mice, causing systemic pathologic changes similar to those reported in humans with virulent influenza A (H5N1) virus infection. (wikipedia.org)
  • In this model, mice are first intranasally inoculated with biofilm-grown pneumococci to establish asymptomatic carriage, followed by IAV infection of both the nasopharynx and lungs. (lu.se)
Virology1
  • In this review, we describe the emergence, virology, geographic range and ecology, and human disease caused by BRBV and discuss potential treatments for active BRBV infections. (cdc.gov)
Viral infection3
  • As a test of the physiologic role of the NLR molecule NLRP3 during RNA viral infection, we explored the in vivo role of NLRP3 inflammasome components during influenza virus infection. (nih.gov)
  • This paper describes a novel mouse model that recreates the transition of pneumococci from asymptomatic carriage to disease upon viral infection. (lu.se)
  • An acute viral infection in humans involving the respiratory tract. (lookformedical.com)
Flaviviridae3
  • Infections with viruses of the family FLAVIVIRIDAE. (uams.edu)
  • This graph shows the total number of publications written about "Flaviviridae Infections" by people in UAMS Profiles by year, and whether "Flaviviridae Infections" was a major or minor topic of these publications. (uams.edu)
  • Below are the most recent publications written about "Flaviviridae Infections" by people in Profiles over the past ten years. (uams.edu)
Vaccines4
  • Vaccines used to prevent infection by viruses in the family ORTHOMYXOVIRIDAE. (lookformedical.com)
  • Given the significant roles of viral and host factors during infection, characterization of these interactions is critical for therapeutic targeting with neutralizing antibodies and vaccines. (bvsalud.org)
  • Surges of serum Abs after immunization and infection are highly specific for the offending Ag, and recent studies demonstrate that vaccines induce transient increases in circulating Ab-secreting cells (ASCs). (syr.edu)
  • Although vaccination is an important strategy to prevent influenza infection, most of the current vaccines cannot provide immediate protection in the event of influenza pandemics and epidemics due to the length of time required for producing effective vaccines. (justia.com)
Immunity1
  • Letvin NL, Kauffman RS, Finberg R. T lymphocyte immunity to reovirus: cellular requirements for generation and role in clearance of primary infections. (umassmed.edu)
Diseases1
Family5
  • Hantavirus Infection Hantaviridae are a family of enveloped single-stranded RNA viruses, which consists of at least 4 serotypes with 9 viruses causing 2 major, sometimes overlapping, clinical syndromes: Hemorrhagic. (msdmanuals.com)
  • The Influenza A virus, which belongs to the Orthomyxoviridae family, can cause influenza in humans, birds or domesticated food animals. (justia.com)
  • Influenza?A infections will be the prototype from the family members Orthomyxoviridae and still have a genome of eight single-stranded RNA sections of bad polarity. (scienceexhibitions.org)
  • Influenza virus is a respiratory virus that is part of the Orthomyxoviridae family. (who.int)
  • Avian Influenza AI The Avian Influenza Virus AIV is an RNA virus belonging to the Orthomyxoviridae family. (pamperedbirds.com)
Antibodies3
  • The present application is drawn to neutralizing monoclonal antibodies for preventing and treating influenza virus infection and methods of treating influenza virus infection. (justia.com)
  • Neutralizing monoclonal antibodies (MAbs), particularly those having cross-clade neutralizing activity, play a critical role in immunoprotection against various influenza A virus (IAV) infections, particularly those caused by the highly pathogenic avian influenza H5N1 virus and any future unpredictable virus strains. (justia.com)
  • Neutralizing antibodies can provide a first line of defense against influenza pathogens and passive immunization with neutralizing MAbs can provide immediate effects to prevent the spread of influenza infection and mortality. (justia.com)
Pathogens1
  • Influenza has a history as one of the world's most serious pathogens, with yearly regional infections and episodic global pandemics. (biomedcentral.com)
Disease7
  • By separating carriage and disease into distinct steps and providing the opportunity to analyze the genetic variants of both the pathogen and the host, this S. pneumoniae/IAV co-infection model permits the detailed examination of the interactions of an important pathobiont with the host at different phases of disease progression. (lu.se)
  • thus, it may be possible for transmission to occur via asymptomatic persons or persons with subclinical disease, who may be unaware that they have been exposed to the infection. (medscape.com)
  • Methods: We established a mouse vaccination model that allows control of disease severity after influenza virus infection despite inefficient induction of virus-neutralizing antibody titers by vaccination. (mssm.edu)
  • It is definitely known that influenza disease infection leads to the induction of apoptosis both in cell tradition and (Takizawa et al. (scienceexhibitions.org)
  • Here we present a case of influenza A and COVID-19 co-infection in a 60-year-old man with end-stage renal disease (ESRD) on hemodialysis. (nebraska.edu)
  • They can be further broken down into subtypes depending on the combination of the proteins on their surface (e.g. influenza A) or different lineages (e.g. influenza B). Infection with influenza viruses causes influenza disease. (who.int)
  • Human infections by influenza A viruses commonly occur yearly, with a seasonal peak incidence [ 6 ], usually as a mild disease, but for some, as a more severe illness that may be fatal. (biomedcentral.com)
Upon influenza A vir1
  • Streptococcus pneumoniae (pneumococcus) is an asymptomatic colonizer of the nasopharynx in most individuals but can progress to a pulmonary and systemic pathogen upon influenza A virus (IAV) infection. (lu.se)
Descriptor1
  • Reoviridae Infections" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
Prevent influenza infection1
  • It thus appears inevitable that, without means to prevent influenza infection, another pandemic will occur within the foreseeable future. (biomedcentral.com)
Vaccination4
  • In contrast, both vaccination and infection induce massive expansion of circulating Ag-specific ASCs without significant increases in the frequencies of ASCs against unrelated Ags. (syr.edu)
  • Results: Vaccination with trivalent inactivated virus vaccine (TIV) reduced morbidity after influenza A virus infection but did not prevent virus replication completely. (mssm.edu)
  • Vaccination limited loss of alveolar macrophages and reduced levels of infiltrating pulmonary monocytes after influenza virus infection. (mssm.edu)
  • Interestingly, TIV vaccination resulted in enhanced levels of eosinophils after influenza virus infection and recruitment of neutrophils in both lungs and mediastinal lymph nodes after bacterial superinfection. (mssm.edu)
Bourbon1
  • Of these viruses, only two have been identified in the United States: Aransas Bay virus (on the southern gulf coast of Texas), from soft ticks found in the nests of seabirds, and Bourbon virus, as a cause of human infection in Kansas and, more recently, in Missouri (although the pathogenesis remains undefined). (medscape.com)
Antigen1
  • The extent and duration of transmission of influenza A/New Jersey/76 virus at Fort Dix, New Jersey, was examined with use of titers of hemagglutination-inhibiting antibody to influenza A/Mayo Clinic/74 (HswlNl) antigen as an index of infection. (usuhs.edu)
Humans1
  • Since its initial discovery, several cases of BRBV infection in humans have been identified in Kansas, Oklahoma, and Missouri. (cdc.gov)
Specificity1
  • Additionally, high specificity of circulating ASCs after antigenic challenge highlights the diagnostic value of interrogating ASCs as an ideal single-time-point diagnostic immune surrogate for serology during acute infection. (syr.edu)
Pandemic2
  • Next generation antivirals are needed to treat seasonal infections and prepare against zoonotic spillover of avian influenza viruses with pandemic potential. (bvsalud.org)
  • For example, both seasonal and pandemic influenza can cause infections in all age groups, and most cases will result in self-limited illness in which the person recovers fully without treatment. (who.int)
Clinical1
  • The possibility of SARS-CoV-2 co-infection should not be overlooked even when other viruses including influenza can explain the clinical symptoms, especially in high-risk patients. (nebraska.edu)
Respiratory syncy1
  • To test this model, we measure the ability of respiratory syncytial virus and influenza virus infection or immunizations to influenza virus, tetanus toxoid, hepatitis B Ag, and human papillomavirus to stimulate bystander memory cells specific for other major environmental Ags that represent a large fraction of the preexisting memory B compartment. (syr.edu)
Pneumococcal1
  • These data help explain pneumococcal virulence after IAV infection and have important implications for studies of S. pneumoniae pathogenesis. (lu.se)
Innate1
  • Additionally, PLpro can cleave both ubiquitin and the ubiquitin-like protein ISG15 from host cell substrates as a mechanism to evade innate immune responses during infection. (bvsalud.org)
Bacterial1
  • Background: Influenza virus infection predisposes to secondary bacterial pneumonia. (mssm.edu)
Replication2
  • These viruses depend on its host for replication and infection. (biomedcentral.com)
  • they occur in a random fashion and the variant viruses that have the best genetically endowed combination of efficient infection, rapid replication, and greatest survival become the dominant populations. (biomedcentral.com)
H5N11
  • Also disclosed herein is a method of treating influenza virus infection in a subject in need thereof comprising administering a therapeutically effective amount of the neutralizing antibody specific for an epitope having at least 90% homology to amino acids +72-115 of the HA1 domain of H5N1 influenza virus hemagglutinin and thereby treating said influenza virus infection in said subject. (justia.com)
Virulent1
  • However, influenza A virus (IAV) infection releases virulent pneumococci from biofilms in vitro and in vivo. (lu.se)
Virus infection3
  • Influenza virus infection is lethal to the chick embryo. (biomedcentral.com)
  • TMP, Zn or saline separately had no effect on embryo survival, none of the embryos survived influenza virus infection. (biomedcentral.com)
  • These two MAbs were proven to inhibit virus infection in the post-attachment process rather than inhibition of receptor binding. (justia.com)
Birds1
  • You can prevent these infections by keeping your parrot away from sick birds and cleaning its environment regularly. (pamperedbirds.com)
Symptoms1
  • A large number of bacteria other than Borrelia i.e., parasites and viruses are transmitted by tick bites and could cause different signs and symptoms in patients, the so-called co - infections (2-5). (fortuneonline.org)
Induction1
  • Inhibition of ROS induction eliminated IL-1beta production in animals during influenza infection. (nih.gov)
Depletion1
  • Notably, mouse ILCs accumulated in the lung after infection with influenza virus, and depletion of ILCs resulted in loss of airway epithelial integrity, diminished lung function and impaired airway remodeling. (nih.gov)