• A different method of producing influenza virus was used to produce the Novartis vaccine Optaflu. (wikipedia.org)
  • June 18, 2007 - The European Commission has approved a cell-culture-derived influenza vaccine and retapamulin 1% ointment for the treatment of impetigo and infected small lacerations, abrasions, or sutured wounds. (medscape.com)
  • On June 13, the European Commission approved an influenza vaccine ( Optaflu , Novartis Pharmaceuticals Corp) for intramuscular use in all 27 member states of the European Union (EU), Iceland, and Norway. (medscape.com)
  • In November 2012, the first cell cultured influenza vaccine, a trivalent subunit inactivated influenza vaccine (Flucelvax(®), ccIIV3), was approved in the US for adults aged ≥ 18 years. (nih.gov)
  • In this vaccine the virus is grown in cell culture instead of in eggs. (wikipedia.org)
  • The vaccine is the first to be made using the company's proprietary cell line, rather than chicken eggs, to provide antigen components, thereby enabling flexible and more rapid manufacturing start-up in the event of a potential pandemic threat. (medscape.com)
  • 3,400), showing that the cell-culture-derived vaccine was comparable to conventional egg-based vaccines in stimulating immune response and tolerability. (medscape.com)
  • Because most circulating viral strains are unable to replicate in chicken eggs, use of the cell line offers the advantage of increased production. (medscape.com)