Ontology gene family encode genes homeobox. Medical search. Frequent questions

Isoform 5a appears to function as a molecular switch that specifies target genes. (nih.gov)
By comparing the transcriptome of mict-L130F vs WD1 and 06-2 ( mict ) vs 06-1 (wildtype, near-isogenic line of 06-2), several potential target genes that may be related to trichome development were identified. (biomedcentral.com)
Many of the target genes by the newly identified miRNAs were associated with plant growth and development, stress response, defense and hormone signaling, and oil synthesis pathways. (springeropen.com)
Nearly one-half are associated with microRNAs (miRNAs), leading to the discovery of many new miRNA genes and their likely target genes. (gsea-msigdb.org)
Using this database, researchers can quickly retrieve the expression level data for target genes in different tissues and in response to different treatments to elucidate gene functions and explore the biology of rapeseed at the transcriptome level. (preprints.org)
Transcription factors (TFs) are proteins that bind to specific DNA sequences of their target genes to regulate gene transcription and thus play an essential role in modulating growth, development, and stress tolerance (Lambert et al. (biomedcentral.com)

This gene encodes paired box protein Pax-6, one of many human homologs of the Drosophila melanogaster gene prd. (nih.gov)
In addition to a conserved paired box domain, a hallmark feature of this gene family, the encoded protein also contains a homeobox domain. (nih.gov)
Description of the protein which includes the UniProt Function and the NCBI Gene Summary. (nih.gov)
Hierarchical classifications for this protein from different ontologies. (nih.gov)
What does this gene/protein do? (cancerindex.org)
What pathways are this gene/protein implicaed in? (cancerindex.org)
members of the family aid protein binding in the brain and are vital to the perception of sound. (wikipedia.org)
LHFPL family members have been studied more so than TMEM211, and protein abundance data shows that each family member, with the exception of LHFPL2, displays its highest abundance level in healthy tissues in the brain. (wikipedia.org)
also known as ASH1), neurogenic differentiation factor 1 (NeuroD1), yes-associated protein 1 (YAP1) and POU class 2 homeobox 3 (POU2F3). (cancerindex.org)
BACKGROUND The histone methyltransferase (HMT) family includes histone lysine methyltransferases (HKMTs) and histone/protein arginine methyltransferases (PRMTs). (cancerindex.org)
Long non-coding RNA (lncRNA) is a type of RNA that contains over 200 nucleotides and that does not encode protein ( 5 , 6 ). (spandidos-publications.com)
The protein symbol is same as the gene symbol, but in regular (non-italic) font, with all characters in upper-case. (tanakalab.org)
Note the differences in gene and protein naming convention among commonly used model organisms in Table 1. (tanakalab.org)
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. (beds.ac.uk)
The Brassica family contains several economically important crops, including rapeseed (Brassica napus, 2n = 38, AACC), the second largest source of seed oil and protein meal worldwide. (preprints.org)
Dipeptidyl peptidase (DPP) 9, DPP8, DPP4 and fibroblast activation protein (FAP) are the four enzymatically active members of the S9b protease family. (preprints.org)
The IB1cDNA encodes a 714 amino acid protein with a proline-rich region and a putative basic helix-loop-helix domain (bHLH). (justia.com)
2018 ). The apple bZIP protein MdHY5 regulates the transcription of MdMYB10 and anthocyanin biosynthesis genes, promoting the expression of nitrate reductase genes and nitrate uptake genes and thereby playing essential roles in anthocyanin accumulation and nitrate assimilation (An et al. (biomedcentral.com)
Neural retina-specific leucine zipper protein is a protein that in humans is encoded by the NRL gene . (en-academic.com)
The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. (en-academic.com)

To identify functional categories overrepresented in the differentially expressed genes, we used integrated gene-network analysis, gene ontology enrichment and mouse phenotype ontology analysis. (biomedcentral.com)
Furthermore, we performed direct enrichment analysis of ASD-associated genes from the SFARI repository in our differentially expressed genes. (biomedcentral.com)
Given the limited number of animals used in the study, we used permissive criteria and identified 842 differentially expressed genes in En2 -/- cerebellum and 862 in the En2 -/- hippocampus. (biomedcentral.com)
Furthermore, when directly compared to the repository of the SFARI database, our differentially expressed genes in the hippocampus showed enrichment of ASD-associated genes significantly higher than previously reported. (biomedcentral.com)
Comparing HESC controls with HESCs deficient in SRC-3, gene enrichment analysis of the differentially expressed gene set revealed an overrepresentation of genes involved in chromatin remodeling, cell proliferation/motility, and programmed cell death. (frontiersin.org)
Using the GSE2223 and GSE59612 datasets, and RNA sequencing data of GBM from The Cancer Genome Atlas, differentially expressed (DE) genes including DE messenger RNAs (DEmRNAs) and DElncRNAs between GBM and normal controls were identified. (spandidos-publications.com)

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. (cancerindex.org)
TGFβ family proteins are well-known pivotal inducers of these events ( 1 ). (aacrjournals.org)
Chemically induced gene expression changes were characterized by qRT-PCR, global run-on sequencing (GRO-seq) and immunoblotting, and the network of cooperative proteins of GATA4 and NKX2-5 were further explored by the examination of the GATA4 and NKX2-5 interactome by BioID. (biomedcentral.com)
Additionally, BioID analysis indicated broad interaction between GATA4 and BET family of proteins, such as BRD4. (biomedcentral.com)
Homeobox proteins are master regulators of develop-ment and control many cellular processes, including proliferation, apoptosis, cell shape, and cell migration. (123dok.net)

qPCR was performed for representative genes to confirm relative transcript levels compared to those detected in microarrays. (biomedcentral.com)
Transcript differences were validated for a subset of DE genes by qPCR. (biomedcentral.com)
Results: In this study, we found high expression of the HOXD9 gene transcript in glioma cell lines and human glioma tissues by quantitative real-time PCR. (123dok.net)
Alternatively spliced transcript variants have been found for this gene. (beds.ac.uk)

The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. (nih.gov)
Genes having at least one occurrence of the highly conserved motif M53 RYTGCNNRGNAAC in the regions spanning 4 kb centered on their transcription starting sites [-2kb, +2kb]. (gsea-msigdb.org)

The objective of this work was the evaluation of muscle transcriptome profile in piglets of both genetic types, in order to identify genes, pathways and regulatory factors responsible for their phenotypic differences. (biomedcentral.com)
To identify genes, signaling pathways and networks that are controlled by SRC-3 and potentially important for hormone-dependent decidualization, we performed RNA-sequencing on HESCs in which SRC-3 levels were significantly reduced at the time of administering the deciduogenic stimulus. (frontiersin.org)
Enriched pathways analysis of these positively correlated genes featured Toll-like receptor and SUMOylation pathways. (preprints.org)

Revealing the intrinsic program of gene regulation that accompanies mammalian retinal development is a key step for eventual cure of many human retina diseases and blindness. (biomedcentral.com)
Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. (en-academic.com)
2018), Identification of retinal homeobox (rax) gene-d. (xenbase.org)

PHTF, a novel atypical homeobox gene on chromosome 1p13, is evolutionarily conserved. (nih.gov)
This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. (nih.gov)
The CsNps was located at a 13.4-kb genomic region on chromosome 3, which region contains three predicted genes. (biomedcentral.com)

The homeobox transcription factor HOXC13 upregulates human papillomavirus E1 gene expression and contributes to viral genome maintenance. (nih.gov)
Transcription factor GATA4-targeted compounds that have previously shown in vivo efficacy in cardiac injury models were tested for stage-specific activation of atrial and ventricular reporter genes in differentiating pluripotent stem cells using a dual reporter assay. (biomedcentral.com)
The Ets variant 2 (ETV2) transcription factor, which belongs to the E26 transformation-specific (ETS) family, has been reported to play a key role in neovascularization. (biomedcentral.com)
The present invention is based on successful expression cloning of a transcription factor that binds to the GTII element of the GLUT2 and insulin genes from a differentiated insulin-secreting cDNA library. (justia.com)
This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. (en-academic.com)
In a genome-wide survey for potential Notch pathway targets, the second intron of the numb gene was found to contain a statistically significant cluster of binding sites for Suppressor of Hairless, the transducing transcription factor for the pathway. (silverchair.com)

In contrast, radial nerve showed an unexpected level of complexity with the expression of 3,370 genes significantly altered more than two-fold with age, including genes involved in nerve function, signaling, metabolism, transcriptional regulation and chromatin modification. (nature.com)
The reduced expression of genes involved in mitochondrial oxidative respiration occurs in early adulthood, before the onset of functional decline, and more abruptly than a damage-response model would predict, which supports the possibility of programmed age-related transcriptional regulation 3 . (nature.com)
Although some enhancers are not conserved and overlap with transposable elements forming clusters, enhancers are generally conserved across thousand Arabidopsis accessions, suggesting they are selected under evolution pressure and could play critical roles in the regulation of important genes. (bvsalud.org)
Further, 21 candidate genes within three potentially novel QTLs were identified, they were mainly involved in the regulation of phytohormone, cell division and proliferation, meristem development, plant or organ development, and carbohydrate transport. (biomedcentral.com)
Here, using 22 transcriptomes of developing maize leaves from dry seeds to 192 h post imbibition, we studied gene up- and down-regulation and functional transition during leaf development and inferred sets of strongly coexpressed genes. (tmu.edu.tw)
We propose that large-scale changes in gene regulation during development are necessary for the final maturation and function of the retina. (biomedcentral.com)
MicroRNAs (miRNAs) are small endogenous RNAs with an approximate length of 18-22 nucleotides and involved in the regulation of gene expression in transcriptional or post-transcriptional levels. (springeropen.com)
The overall results provide a systematic view of gene regulation in the human, which will be refined as additional mammalian genomes become available. (gsea-msigdb.org)

Gene expression is a key determinant of cellular phenotype, and genome-wide expression analysis can provide insight into the molecular events underlying complex processes such as aging. (nature.com)
Molecular characterization of a novel gene family (PHTF) conserved from Drosophila to mammals. (nih.gov)
This study provides a complementary genome-wide view of common gene dynamics and a broad molecular classification of mouse retina development. (biomedcentral.com)

LIM homeobox 6 [Source:HGNC Sym. (gsea-msigdb.org)

There was an age-related upregulation in expression of genes involved in synaptogenesis, axonogenesis and neuroprotection suggesting preservation of neuronal processes with age. (nature.com)
Several studies have analyzed genome-wide expression profiles of ASD patients using lymphoblastoid cell lines and blood samples, supporting upregulation of immune genes and downregulation of neurodevelopmental genes as key players in the pathogenesis of ASD (see [ 8 ] for a review). (biomedcentral.com)
In murine mammary gland cells (NMuMG), Tβ4 upregulation is required for full induction of a MRTF-regulated EMT gene expression program after TGFβ stimulation. (aacrjournals.org)

Sequence analysis showed that only one single nucleotide mutation (C → T) between 9930 and nps was found in the second exon of Csa3G748220 , a plant-specific class I HD-Zip gene. (biomedcentral.com)
family with sequence similarity. (gsea-msigdb.org)
When tested in vitro, IB1 bound specifically to the GTII cis element of the GLUT2 gene and to an homologous regulatory sequence of the insulin promoter termed RIPE3. (justia.com)

Gene expression profiles in animals that exhibit slow aging or negligible senescence may reveal distinct insight into potential mechanisms involved in long-term maintenance of tissues and healthy aging. (nature.com)
Few genes show differential expression with age in tissues (brain, liver and kidney) of naked mole rats and, contrary to other mammals and short-lived model animals, mitochondrial gene expression does not change with age 13 . (nature.com)
Gene expression stability during aging was also observed in tissues of the long-lived giant mole-rat ( Fukomys mechowii ) with a maximum lifespan of more than 20 years 14 . (nature.com)
Using a sequential blast pipeline, we phylogenetically classified these genes, as well as those associated with other tissues, in order to define tissue-specific profiles of gene emergence. (biomedcentral.com)
Our comparative analyses show that, among different tissues, the neural crest exhibits a particularly high rate of gene emergence during vertebrate evolution. (biomedcentral.com)
Secreted from neighboring tissues, signaling molecules of the Wnt, Fgf, and Bmp families cooperate to activate a distinct combination of transcription factors at the neural plate border. (biomedcentral.com)
Spatio-temporal expression pattern showed that these genes were expressed in many tissues with different levels, and they had distinct expression pattern during adventitious root formation and development. (biomedcentral.com)
Therefore, while GLUT2 levels are unchanged or even upregulated in several tissues such as the liver and the intestine during the hyperglycemic conditions observed in diabetes, the same gene undergoes a drastic dysregulation only in the pancreatic islets. (justia.com)

Age-related gene expression profiles of the short-lived model animals Caenorhabditis elegans and Drosophila melanogaster share a common adult-onset expression program of genes involved in mitochondrial metabolism, DNA repair, catabolism, peptidolysis and cellular transport 3 . (nature.com)

Using less stringent statistical criteria (uncorrected p -values), also the gene SPATA16 , which has a pivotal role in male fertility and for which episodes of adaptive evolution have been suggested, also displays a putative signal of diversifying selection in the human branch. (biomedcentral.com)
The putative miRNAs belong to 12 individual miRNA family and most of them have higher (A + U) content ranging from 47.36 to 77.77% than their respective miRNA homologs. (springeropen.com)

Total count of NCBI Gene Reference Into Function hits for target listed in parenthesis, and summary table with links to publications per PMID with the specific text in article that includes the reported target. (nih.gov)

The role of HMT gene variants in prostate cancer remains unknown. (cancerindex.org)
Third, even using currently available comprehensive arrays, tissue-specific genes are still under-represented, including alternatively spliced variants or genes that are only briefly expressed in a tissue-specific pattern. (biomedcentral.com)

In this study, 23 HD-Zip genes distributed on 6 chromosomes were identified from the peach ( Prunus persica ) genome, and named PpHDZ01-23 according to their positions on the chromosomes. (biomedcentral.com)
Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. (nih.gov)

The expression of immunity and metabolism-related genes (BS2A1, PIWIL2 and Fads1) significantly decreased at all-time points compared to the control group. (frontiersin.org)
Among 4,180 transcripts that changed significantly during development, approximately 2/3 of the genes were expressed at high levels up until PN5 and then declined whereas the other 1/3 of the genes increased expression from PN5 and remained at the higher levels until at least PN21. (biomedcentral.com)
Tβ4-knockout B16F1 (Tβ4 KO) clones show significantly diminished expression level of tumor-associated genes, which is regulated by the TGFβ/MRTFs pathway. (aacrjournals.org)
Overexpression of RsmA , a bZIP TF-coding gene in Aspergillus nidulans , significantly increases secondary metabolite production and confers resistance against predation. (biomedcentral.com)

We used this information to develop the BrassicaEDB, including eFP, Treatment, Coexpression, and SRA Project modules based on gene expression profiles and Gene Feature, qPCR Primer, and BLAST modules based on gene sequences. (preprints.org)

To determine the origin of neural crest genes, we analyzed Phenotype Ontology annotations to select genes that control the development of this tissue. (biomedcentral.com)
This is in line with the mouse gene nomenclature and it follows current axolotl gene annotations 2 . (tanakalab.org)

Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus (GEO) repository. (cancerindex.org)
In this study, the gene expression profile in GBM was analyzed using a microarray dataset and RNA-sequencing (RNA-Seq) datasets. (spandidos-publications.com)

Knockouts or loss of function mutations to these family members cause complete or partial deafness in humans and mice that is then inherited in an autosomal recessive pattern. (wikipedia.org)
Gene expression profiles obtained without artifacts introduced by isolation procedures or gene mutations provide a valuable overview of retina development under natural developmental conditions. (biomedcentral.com)
Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. (beds.ac.uk)
Cancer genome sequencing reveals diverse acquired mutations in CTCF , which we have shown, functions as a tumour suppressor gene. (preprints.org)

Enhancers are critical cis-regulatory elements controlling gene expression during cell development and differentiation. (bvsalud.org)

Based on the competing endogenous RNA hypothesis, DElncRNA‑micro RNA (miRNA)‑DEmRNA interactions were obtained by target gene prediction. (spandidos-publications.com)
Gene Ontology (GO) and Kyoto Encyclopedia of Gene and Genomes pathway analysis of DEmRNAs in the DElncRNA‑miRNA‑DEmRNA network was performed. (spandidos-publications.com)
Based on the ceRNA hypothesis ( 15 ), the lncRNA-miRNA-mRNA network was constructed and Gene Ontology (GO) and Kyoto Encyclopedia of Gene and Genomes (KEGG) pathway analysis of mRNAs in the network were performed. (spandidos-publications.com)
Our results suggest that previous estimates of the number of human miRNA genes were low, and that miRNAs regulate at least 20% of human genes. (gsea-msigdb.org)

The homeodomain domain is generally composed of about 60 amino acids encoded homeobox, which form three alpha helices. (biomedcentral.com)

We propose that the evolution of the neural crest is linked not only to the recruitment of ancestral regulatory genes but also to the emergence of signaling peptides that control the increasingly complex lineage diversification of this plastic cell population. (biomedcentral.com)
Positive selection acts on eQTLS and sQTLs, indicating selective effects on important gene regulatory functions. (biomedcentral.com)
Pharmacological modulation of cell fate decisions and developmental gene regulatory networks holds promise for the treatment of heart failure. (biomedcentral.com)
Collectively, these results indicate the potential for therapeutic alteration of cell fate decisions and pathological gene regulatory networks by GATA4-targeted compounds modulating chamber-specific transcriptional programs in multipotent cardiac progenitor cells and cardiomyocytes. (biomedcentral.com)
Transcriptional activator Islet-Brain 1 (IB1) is disclosed which is involved in the control of the GLUT2 and insulin genes by interacting with homologous cis-regulatory elements of the GLUT2 and insulin promoters, and to materials and methods deriving from this work. (justia.com)

Often a gene, mRNA and cDNA need to be distinguished in a text. (tanakalab.org)
In such cases, we recommend putting "gene", "mRNA" or "cDNA" in regular font in parentheses in front of the gene symbol. (tanakalab.org)
Gene, mRNA or cDNA words must be omitted to describe a gene when there is no ambiguity or after describing once in the beginning of the communication. (tanakalab.org)

Genome-wide transcriptional profiling using RNA-Seq revealed few age-related changes in gene expression in muscle and esophagus tissue. (nature.com)
This gene encodes a member of the trithorax group of transcriptional activators. (cancerindex.org)
In particular, the transcriptional diversity regulated by sQTLs in testis-enriched genes may be important for spermatocytes to respond to environmental and physiological stress. (biomedcentral.com)
MKL1 and MKL2 ), or robust SRF transcriptional coactivators, have been reported to organize actin cytoskeletal rearrangement and regulate cell motility by controlling the expression of dozens of cytoskeletal/adhesion genes ( 4-6 ). (aacrjournals.org)
These small non-coding RNAs derived from their precursor sequences, bind to their target mRNAs and negatively mediate the gene expressions in pre-transcriptional or post-transcriptional stages by impeding mRNA translation [ 12 , 13 ]. (springeropen.com)

The identification of neural crest specification genes expressed in the neural plate of basal chordates, in addition to the discovery of pigmented migratory cells in ascidians, has challenged this hypothesis. (biomedcentral.com)
A comparative -omics study often requires identification of orthologous genes across salamander species. (tanakalab.org)
Identification of ZEB2 as an Immune-Associated Gene in Endometrial Carcinoma and Associated with Macrophage Infiltration by Bioinformatic Analysis. (beds.ac.uk)
Comprehensive identification of all functional elements encoded in the human genome is a fundamental need in biomedical research. (gsea-msigdb.org)

Here, it is demonstrated that TGFβ facilitates Tβ4 expression and leads to the activation of myocardin-related transcription factors (MRTF), which are coactivators of serum response factor (SRF) and regulate the expression of genes critical for the epithelial-mesenchymal transition (EMT) and tumor metastasis. (aacrjournals.org)

Correlation among the expression of these RF and DE genes show relevant differences between genetic types. (biomedcentral.com)
A correlation coefficient analysis of gene expression during retina development between previous SAGE studies and this study was also carried out. (biomedcentral.com)

High expression of genes that positively correlated with overexpression of DPP4, DPP8, and DPP9 were associated with very poor survival in HCC. (preprints.org)

Six individual gene expression clusters were identified based on expression patterns of transcripts through retina development. (biomedcentral.com)
Different genes in the same functional clusters are expressed in the different developmental stages, suggesting that cells might change gene expression profiles from differentiation to maturation stages. (biomedcentral.com)

We determined the expression patterns of 101,040 genes via FPKM analysis and displayed the results using the eFP browser. (preprints.org)

Therefore, we aimed to analyze the biological roles of UvbZIP6 , a member of the bZIP family in U. virens . (biomedcentral.com)
2013 ). Under H 2 O 2 stress conditions, fission yeast increases the expression levels of bZIP TF genes ATF1 and PCR1 to successfully adapt to oxidative stress (Fernández-Vázquez et al. (biomedcentral.com)

Cerebellar and hippocampal tissue samples from three En2 -/- and wild type (WT) littermate mice were assessed for differential gene expression using microarray hybridization followed by RankProd analysis. (biomedcentral.com)
Using F 2 and BC 1 populations constructed from a cross between nps and '9930', the genetic analysis showed that the nps trait is controlled by a single recessive nuclear gene. (biomedcentral.com)
A combination of genetic mapping and candidate gene analysis presents Cdkn2c, a gene encoding for cyclin kinase inhibitor p18INK4c (p18), as the top candidate gene for inducing the Slec2c1 associated expansion of B1a cells. (gsea-msigdb.org)
Analysis of ZEB2 gene variation in two patients with Mowat-Wilson syndrome]. (beds.ac.uk)

Gene symbols, accession ids and various other target identifiers. (nih.gov)

Furthermore, RsmA binds to the promoter region of aflR in the sterigmatocystin gene cluster , which encodes a C6 TF (Yin et al. (biomedcentral.com)

Due to cellular heterogeneity in the heart, the activation of gene programs representing specific atrial and ventricular cardiomyocyte subtypes would be highly desirable. (biomedcentral.com)

Recent human transcriptomic analyses revealed a very large number of testis-enriched genes, many of which are involved in spermatogenesis. (biomedcentral.com)
In the human lineage (after correction for multiple testing) we found that only the gene TULP2 , for which no functional data are yet available, is subject to episodic positive diversifying selection. (biomedcentral.com)
At the same time, we found evidence for recent positive directional selection acting on several human testis-enriched genes ( MORC1 , SLC9B1 , ROPN1L , DMRT1 , PLCZ1 , RNF17 , FAM71D and WBP2NL ) that play important roles in human spermatogenesis and fertilization. (biomedcentral.com)
Episodic diversifying selection, possibly driven by sperm competition, was not an important force driving the evolution of testis-enriched genes in the human lineage. (biomedcentral.com)
In multiple human cancers, Tβ4 levels correlate positively with TGFβ1 and the tumor-associated gene expression levels through processes that respectively depend on TGFβ receptor 1 (TGFBR1) and MRTF expression. (aacrjournals.org)
Network properties of complex human disease genes identified through genome-wide association studies. (leibniz-fli.de)
This comprehensive data mining suggests that DPP9 is essential for human survival and the DPP4 protease family is important in cancer pathogenesis. (preprints.org)

GATA4-targeted compounds 3i-1000 and 3i-1103 were identified as differential modulators of atrial and ventricular gene expression. (biomedcentral.com)

Of neural crest genes, 9% are vertebrate innovations. (biomedcentral.com)
A remarkable proportion of the new neural crest genes encode soluble ligands that control neural crest precursor specification into each cell lineage, including pigmented, neural, glial, and skeletal derivatives. (biomedcentral.com)

Our results showed the roles of PpHDZs on root formation, which is helpful to better understand the classification and function of peach HD-Zip genes. (biomedcentral.com)

Within the same functional classes, however, different gene populations were expressed in distinct developmental phases. (biomedcentral.com)

This comprehensive transcriptomic data lead us to the question whether positive selection was a decisive force influencing the evolution and variability of testis-enriched genes in humans. (biomedcentral.com)

QTLs and candidate genes detected in our study for yield-related traits under stripe rust stress will facilitate elucidating genetic basis of yield-related trait and could be used in marker-assisted selection in wheat yield breeding. (biomedcentral.com)
Candidate genes with known effects on muscle growth were found among the DE genes upregulated in DU×IB. (biomedcentral.com)
The method requires not only evolutionary conservation of candidate TFBSs and sets of strongly coexpressed genes but also that the genes in a gene set share the same Gene Ontology term so that they are involved in the same biological function. (tmu.edu.tw)

We also analysed the impact of CTCF haploinsufficiency by examining gene expression changes in CTCF -altered endometrial carcinoma. (preprints.org)

Approved gene symbol with link to HUGO Gene Nomenclature Committee. (nih.gov)
A gene symbol is described by a series of alphanumeric characters, where the first character is upper-case italics and the rest are lower-case italics. (tanakalab.org)
When there is no ambiguity of species used for the study, the species symbol must be omitted when describing the gene. (tanakalab.org)

Anatomy28

Organisms25

Diseases1

Chemicals and Drugs38

Analytical, Diagnostic and Therapeutic Techniques and Equipment28

Phenomena and Processes73

Disciplines and Occupations14

Technology, Industry, Agriculture5

Humanities2

Information Science53

Health Care6

Target genes6

Protein20

Differentially expressed6

Proteins5

Transcript4

Highly conserved2

Pathways3

Retinal3

Chromosome3

Transcription factor6

Regulation8

Molecular3

Source:HGNC Sym1

Upregulation3

Sequence3

Tissues8

Drosophila1

Putative2

PMID1

Variants2

Chromosomes2

Significantly4

QPCR1

Annotations2

Datasets2

Mutations4

Controlling gene expression1

MiRNA4

Amino1

Regulatory5

CDNA3

Transcriptional5

Identification4

Regulate1

Correlation2

Overexpression1

Clusters2

Patterns1

BZIP2

Analysis4

Accession1

Cluster1

Cellular1

Human7

Differential1

Neural2

Roles1

Functional1

Humans1

Candidate3

Endometrial Carcinoma1

Symbol3