AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHealth Care
InflammationInflammation MediatorsMice, Inbred C57BLDisease Models, AnimalCytokinesMice, KnockoutPneumoniaLungAnti-Inflammatory AgentsNeurogenic InflammationInterleukin-6Tumor Necrosis Factor-alphaBronchoalveolar Lavage FluidC-Reactive ProteinBiological MarkersNeutrophilsMacrophagesColitisLipopolysaccharidesOvalbuminMice, Inbred BALB CDermatitisCells, CulturedRespiratory HypersensitivitySignal TransductionCarrageenanAsthmaNF-kappa BInterleukin-1betaBronchial HyperreactivityChemokinesEosinophilsNeutrophil InfiltrationLeukocytesRNA, MessengerEdemaGene Expression RegulationPeroxidaseAllergensChronic DiseaseInterleukin-8HypersensitivityChemokine CCL2Mice, TransgenicOxidative StressTh2 CellsAnti-Inflammatory Agents, Non-SteroidalTime FactorsImmunohistochemistryRats, Sprague-DawleyIntestinal MucosaInflammatory Bowel DiseasesArthritis, ExperimentalReverse Transcriptase Polymerase Chain ReactionIntercellular Adhesion Molecule-1VasculitisDextran SulfateUp-RegulationEnzyme-Linked Immunosorbent AssayColonEncephalitisImmunity, InnateMonocytesSkinAcute DiseaseTurpentineAtherosclerosisIleitisLeukocyte CountInterleukin-1ArteritisChemotaxis, LeukocyteInterleukin-10ArthritisCyclooxygenase 2Trinitrobenzenesulfonic AcidCell MovementApoptosisFibrosisGene ExpressionInterleukin-17Toll-Like Receptor 4EosinophiliaEndothelium, VascularT-LymphocytesFreund's AdjuvantInterferon-gammaImmunoglobulin EFlow CytometrySynovitisUveitisLipoxinsLiverNephritisPleurisyArthritis, RheumatoidVascular Cell Adhesion Molecule-1BronchitisCell LinePulmonary Eosinophilia
AbstractSystemic inflammationInfectionMarkers of low grade inflammationSigns of inflammationAirway inflammationBiomarkersCytokineClinicalCardiovascular diseaseCartilage and boneAssociated with cardiovascularProteinLocal inflammationJoint inflammationVascular inflammationMiceAssessmentLungQuantificationPulmonaryPersistentExtracellular matrixNeutrophilsAutoimmuneInflammatoryEvaluateEndothelialRheumatoid arthritisAtherosclerosisLipidsGlycoproteinTherapeuticExplainItchProvokeInsulinPathogensCancersComplicationsEczemaTissueInvestigateReducesTreatmentDescribeBoneSymptomsTumorMolecularDetermineAssociationsPrevalenceDamage
Abstract1
  • article{fbdfaeec-c72b-4d3b-95e1-ec34a302ede8, abstract = {{The objective of this study is to clarify use of the term mastitis in empirical studies of lactational mastitis. (lu.se)
Systemic inflammation4
  • To assess associations between baseline values of four different circulating markers of inflammation and future risk of coronary heart disease, potential triggers of systemic inflammation (such as persistent infection), and other markers of inflammation. (bmj.com)
  • Objective Improved systemic inflammation is certainly connected with stress-related psychopathology. (healthanddietblog.info)
  • 4 5 6 7 Systemic inflammation could represent the underlying mechanism that links oral health and cardiovascular disease. (bmj.com)
  • Similarly, consistent objective evidence of systemic inflammation, cytokine excess, or immune system activation in relation to symptoms is lacking. (msdmanuals.com)
Infection4
  • These markers of inflammation might, however, be indicators of chronic infective processes possibly correlated with risk of coronary heart disease, such as infection by Chlamydia pneumoniae or chronic gastric infection with Helicobacter pylori . (bmj.com)
  • Infection may lead to inflammation, atherosclerosis and thrombotic vascular events. (uwi.edu)
  • Four articles suggested that mastitis was an infection, 4 made no mention of the etiology of symptoms, and 10 articles described mastitis as an inflammation or an infection. (lu.se)
  • 13] The inflammation and necrosis observed during HAV infection does not appear to be a direct viral effect but rather an effect of the immune cell response induced by the viral infection. (medscape.com)
Markers of low grade inflammation2
  • Several reports have suggested that plasma C reactive protein and other possible markers of low grade inflammation can predict increased risks of coronary heart disease, but it is not known whether the associations are causal. (bmj.com)
  • 1 Inflammation plays an important role in the pathogenesis of atherosclerosis, and markers of low grade inflammation have been consistently associated with a higher risk of cardiovascular disease. (bmj.com)
Signs of inflammation1
Airway inflammation2
Biomarkers5
  • Nine hundred and sixty-two adolescents (442 boys and 520 girls) from nine European countries met the inclusion criteria of having measurements for the homeostasis model assessment (HOMA) and a set of inflammation-related biomarkers: C-reactive protein (CRP), tumor necrosis factor alpha (TNF-α), interleukin (IL-6), complement factors C3 and C4 and selected cell adhesion molecules. (isciii.es)
  • Associations of Plasma Biomarkers of Inflammation, Fibrosis, and Kidney Tubular Injury With Progression of Diabetic Kidney Disease: A Cohort Study. (bvsalud.org)
  • Plasma biomarkers of inflammation / fibrosis ( TNFR1 and TNFR2 , suPAR, MCP-1, YKL-40) and tubular injury (KIM-1) measured at the baseline visit. (bvsalud.org)
  • METHODS: Cross-sectional data from 13 (PSC) and 12 (WRA) countries within the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project were used. (cdc.gov)
  • Objective: Diagnosis of ventriculostomy related infections (VRI) in the neuro-intensive care unit remains challenging and current biomarkers lack adequate precision. (lu.se)
Cytokine1
Clinical5
  • Methods: Participants underwent an AC inflammation evaluation including: clinical cell and flare grading and laser flare photometry (LFP). (unimi.it)
  • The present study evaluated the clinical relevance of an integrative preoperative assessment of inflammation-, nutrition-, and muscle-based markers for patients with muscle-invasive bladder cancer (MIBC) undergoing curative radical cystectomy (RC). (karger.com)
  • 0.001) were also found between calprotectin and both laboratory and clinical markers of inflammation. (bmj.com)
  • The main objective of the intervention(s) being evaluated by the clinical trial. (uclahealth.org)
  • The clinical presentation, cutaneous findings, and likely presence of RVC-positive granulocytes in bone marrow provide potential support to the evolving hypothesis of persistent RuV within neutrophils contributing to chronic granulomatous inflammation in a milieu of immune dysregulation. (cdc.gov)
Cardiovascular disease4
  • However, excessive or unresolved inflammation can damage healthy tissue and result in chronic inflammatory conditions such as rheumatoid arthritis, ulcerative colitis, cardiomyopathies, cardiovascular disease, and asthma. (nature.com)
  • Objective To examine if self reported toothbrushing behaviour is associated with cardiovascular disease and markers of inflammation (C reactive protein) and coagulation (fibrinogen). (bmj.com)
  • Conclusions Poor oral hygiene is associated with higher levels of risk of cardiovascular disease and low grade inflammation, though the causal nature of the association is yet to be determined. (bmj.com)
  • 2 Consequently, contributing factors associated with inflammation and chronic infections, including oral infections such as periodontal disease, have been investigated to explain the relation between dental disease and cardiovascular disease. (bmj.com)
Cartilage and bone2
  • Histologic analysis confirmed the suppression of joint inflammation and showed prevention of cartilage and bone destruction after anti-IL-17 antibody therapy. (nih.gov)
  • inflammation and progressive damage to cartilage and bone causes pain and stiffness, makes movement difficult, and leads to serious disability. (laskerfoundation.org)
Associated with cardiovascular1
Protein3
  • Baumeister D, Akhtar R, Ciufolini S et al (2015) Childhood trauma and adulthood inflammation: a meta-analysis of peripheral C-reactive protein, interleukin-6 and tumour necrosis factor-α. (springer.com)
  • 2 3 Moreover, highly sensitive assays for C reactive protein and serum amyloid A protein are now available that can detect low grade inflammation that would previously have been unnoticed. (bmj.com)
  • Multivariable linear models were constructed that included zinc status (plasma/serum zinc concentrations), Hb concentrations and anemia, iron status, age, sex, and inflammation (C-reactive protein and -1-acid glycoprotein). (cdc.gov)
Local inflammation2
  • Recent studies have suggested that the local inflammation is not only detrimental but can also be beneficial for the repair process. (europa.eu)
  • This activates the innate immune system and local inflammation. (bmj.com)
Joint inflammation1
Vascular inflammation2
  • Review the potential therapeutic targets in the treatment of vascular inflammation: current and future research. (pcna.net)
  • Dyslipidemia is associated with vascular inflammation and stiffness. (asn-online.org)
Mice6
Assessment2
  • Conclusions: Anterior segment SS-OCT could be used for a comprehensive assessment of AC inflammation, providing objective measurements of inflammatory cells and aqueous flare. (unimi.it)
  • Analysis of the objective data confirmed this subjective assessment. (thehorse.com)
Lung6
  • We aimed to develop a new regenerative therapeutic that can treat this inflammation and promote lung healing thereby having potential benefit to thousands of Californians. (ca.gov)
  • Pro-healing biomaterial to treat lung inflammation and promote recovery. (ca.gov)
  • We aim to develop a new therapeutic that can treat this inflammation and promote lung healing thereby having potential benefit to thousands of Californians. (ca.gov)
  • Our team studies danger signals, sensors and signaling pathways involved in lung inflammation in conditions such as Acute Respiratory Distress Syndrome (ARDS), pulmonary fibrosis and emphysema. (univ-orleans.fr)
  • Repeated exposure to cigarette smoke is the leading cause of chronic lung inflammation and pulmonary emphysema characterized by irreversible damage of alveolar walls. (univ-orleans.fr)
  • We are currently studying the emerging functions of canonical (NLRP3, NLRP6) and non-canonical inflammasomes, related to the influence of the gut and lung microbiota on lung inflammation. (univ-orleans.fr)
Quantification1
Pulmonary1
  • Objective: Workers exposed to dusts from concentrated animal feeding operations have a high prevalence of pulmonary diseases. (cdc.gov)
Persistent7
  • Persistent inflammation on Pap smear: Does it warrant evalua. (lww.com)
  • Persistent inflammation on Pap smear: Does it warrant evaluation? (lww.com)
  • This study was carried out with the aim to evaluate whether women with persistent inflammation on Pap smear need further evaluation with colposcopy. (lww.com)
  • Women with persistent inflammation on Pap smear were then subjected to colposcopy and directed biopsy if required. (lww.com)
  • Nearly 16.67% women with persistent inflammation on Pap smear had cervical intraepithelial neoplasia. (lww.com)
  • Hence, a large number of women with CIN would be missed if persistent inflammation on Pap smear is not evaluated further. (lww.com)
  • 1 2 In recent years these "acute phase reactants" have been studied as potential markers of more subtle and persistent systemic alterations that may be loosely called low grade inflammation. (bmj.com)
Extracellular matrix3
  • We have successfully tested this new infusible extracellular matrix therapeutic in a mouse model of severe inflammation. (ca.gov)
  • In this study, we used the OrganoPlate to develop a humanized 3D in vitro inflammation-on-a-chip model to recapitulate neutrophil transmigration across the endothelium and subsequent migration through the extracellular matrix (ECM). (nature.com)
  • During an inflammatory response, neutrophils move from the blood to the site of inflammation by transmigrating across the endothelial barrier and through the basement membrane (BM) of the surrounding extracellular matrix (ECM). (nature.com)
Neutrophils1
Autoimmune1
  • These agents are thought to re-educate [1] the immune system to a level that the recurrent autoimmune inflammation of ocular tissues are prevented. (aao.org)
Inflammatory3
  • The objective of t his proposal is to understand the role of anti-beta2-GPI antibodies and SAA in activating pro-thrombotic inflammatory responses in the endothelium and to determine the inhibitory effects by which LXA4 could counteract these molecular signaling pathways. (europa.eu)
  • In this course, Donna Arnett, PhD, MSPH discusses inflammation and chronic inflammatory disease in the context of atherosclerosis. (pcna.net)
  • Inflammatory diseases are often characterised by excessive neutrophil infiltration from the blood stream to the site of inflammation, which damages healthy tissue and prevents resolution of inflammation. (nature.com)
Evaluate1
  • The objective was to evaluate the impacts of a complex environment and stocking density on Ross 708 broiler chicken behaviors. (awionline.org)
Endothelial2
Rheumatoid arthritis1
  • He chose rheumatoid arthritis, because it would provide the opportunity to study tissue at the height of inflammation, which was not possible in Graves' disease: Doctors routinely remove diseased tissue from rheumatoid arthritis patients to relieve symptoms. (laskerfoundation.org)
Atherosclerosis3
  • Explain the relationship between inflammation, atherosclerosis, and established CVD risk factors. (pcna.net)
  • Moreover, a range of PET tracers has been independently employed to investigate the association of atherosclerosis disease with specific molecular processes in plaques, such as inflammation with 18F-Fluorodeoxyglucose (18F-FDG) or micro-calcification with 18F-sodium fluoride (18F-NaF). (snmjournals.org)
  • Thus, we aim at the co-registered in-vivo imaging of inflammation and micro-calcification processes in carotid plaques to enable parallel evaluations of any potential correlations between their activity progress and response to therapy at different stages of atherosclerosis. (snmjournals.org)
Lipids2
  • She describes inflammation as a process that links lipids to ASCVD and covers the interconnections between diet, genetics, and physical activity. (pcna.net)
  • This is a randomized placebo-controlled study in treated and suppressed HIV-infected individuals aged ≥40 years with either known CVD or 1 CVD risk factor to study the effect of Bempedoic acid (BA) on safety, arterial inflammation as assessed by FDG-PET/CT, lipids, inflammation, immune activation, cardiometabolic indices, and non-calcified plaque (NCP) in the coronary arteries (assessed by coronary CT angiography, CCTA). (uclahealth.org)
Glycoprotein1
  • BACKGROUND: The von Willebrand factor (VWF) is a multimeric plasma glycoprotein essential for hemostasis, inflammation, and angiogenesis. (imperial.ac.uk)
Therapeutic2
  • The overriding social objective of our project is to develop a novel therapeutic strategy which will shorten the recovery phase, minimize the motor impairments, and improve the patients'quality of life after stroke. (europa.eu)
  • Effects of psychotropic drugs on inflammation: consequence or mediator of therapeutic effects in psychiatric treatment? (springer.com)
Explain1
Itch1
  • Olive oil is currently used in topical applications for the treatment of several skin conditions, including dry skin, itch, and inflammation as well as disorders such as rosacea. (researchgate.net)
Provoke1
Insulin1
  • Inflammation is related to insulin resistance in adults, especially on those individuals with high levels of body composition. (isciii.es)
Pathogens1
  • The presence of objective signs of vulvar inflammation in the absence of vaginal pathogens, along with a minimal amount of discharge, suggests the possibility of mechanical or chemical irritation of the vulva. (cdc.gov)
Cancers2
  • The objectives of this project are to elucidate the reasons for the increased incidence of prostate cancer among WTCHP participants and to explore the behavior of these cancers. (cdc.gov)
  • To investigate markers of inflammation in prostate cancer samples from WTCHP patients and matched prostate cancers not related to WTC. (cdc.gov)
Complications1
  • In ocular inflammation, they are used as steroid-sparing agents to control the inflammation with a target for durable remission and prevention of sight-threatening complications of uveitis. (aao.org)
Eczema1
  • The use of topical oil has also been reported in recent years to be effective in treating xerosis, rosacea, psoriasis, atopic dermatitis, contact dermatitis, eczema (including severe hand and foot eczema), seborrhea, pruritus, and various inflammations. (researchgate.net)
Tissue1
Investigate1
  • Objectives: To investigate factors contributing to neonatal admission outcomes at Effia Nkwanta Regional Hospital (ENRH) Method: All neonatal admissions to the Neonatal & Intensive Care Unit (NICU) of the hospital that were entered into the DHIMS2 database were extracted and complemented with additional information from patients' folder review. (bvsalud.org)
Reduces1
  • We found that intravenous infusion of the material significantly reduces inflammation across the body, including the lungs, suggesting it has the potential to treat severe COVID-19 pathology. (ca.gov)
Treatment2
  • Women with inflammation on Pap smear were given treatment as per WHO guidelines and Pap smear was repeated at an interval of 6-12 weeks. (lww.com)
  • 4. Discuss the modes of treatment of inflammation. (txed.net)
Describe2
  • 2. Describe the local & systemic effects of inflammation. (txed.net)
  • The objective of this study was to describe the ontogeny of the severe feather pecking (SFP), gentle feather pecking (GFP), aggressive pecking (AP), and enrichment pecking (EP) of non-beak-trimmed Lohmann Brown (LB)-pullets during the first. (awionline.org)
Bone1
Symptoms1
  • M. genitalium is associated with symptoms of urethritis and urethral inflammation and accounts for 15%-25% of NGU cases in the United States ( 691 - 693 , 696 , 697 , 700 ). (cdc.gov)
Tumor1
  • Inflammation is known to promote both tumor development and progression. (cdc.gov)
Molecular1
  • We will analyze immunohistochemical and molecular markers of inflammation in archival prostate cancer samples from WTCHP patients, and matched controls. (cdc.gov)
Determine1
  • To determine the effects of TMJ inflammation on horse movement and rein tension, Carmalt's team evaluated six horses long-reined on a treadmill at the walk and trot. (thehorse.com)
Associations1
  • OBJECTIVES: In this study we assessed associations between zinc status and hemoglobin (Hb) concentrations and anemia in preschool children 6-59 mo old (PSC) and nonpregnant women of reproductive age 15-49 y old (WRA) in population-based nutrition surveys. (cdc.gov)
Prevalence1
  • Objective: This study aimed to assess the prevalence of and mortality associated with SAM. (bvsalud.org)
Damage1
  • The objective of the present study was to examine correlations between calprotectin and joint damage. (bmj.com)