• Human coronaviruses (HCoVs) first were identified in 1965 as a common cause of mild upper and lower respiratory infections in children and adults, similar to illness produced by rhinoviruses and respiratory syncytial virus. (medscape.com)
  • Before the emergence of SARS-1 and Middle East respiratory syndrome (MERS), all coronaviruses were thought to only cause trivial respiratory illness and occasionally gastroenteritis, so little research focused on these viral pathogens. (medscape.com)
  • HCoV-229E is also among the coronaviruses most frequently codetected with other respiratory viruses, particularly with human respiratory syncytial virus (HRSV). (wikipedia.org)
  • HCoV-229E is one of the seven human coronaviruses which include HCoV-NL63, HCoV-OC43, HCoV-HKU1, MERS-CoV, SARS-CoV-1, and SARS-CoV-2 and are globally distributed. (wikipedia.org)
  • HCoV-229E is one of seven known coronaviruses to infect humans. (wikipedia.org)
  • Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? (mdpi.com)
  • Human rhinoviruses (HRVs) are a highly prevalent cause of acute respiratory infection in children. (plos.org)
  • While respiratory viruses such as influenza A/B, respiratory syncytial virus (RSV), human metapneumovirus (hMPV), rhinoviruses (HRV), etc. dominate the RTIs, 10-15% of patients develop secondary bacterial coinfection [ 2 ]. (healthtrackrx.com)
  • Human coronavirus strains have remained endemic in the United States since 1965, when these viruses first were isolated and characterized. (medscape.com)
  • In 2002, a new strain of coronavirus emerged that caused severe acute respiratory syndrome 1 (SARS-1), designated SARS-CoV-1. (medscape.com)
  • Human coronavirus 229E (HCoV-229E) is a species of coronavirus which infects humans and bats. (wikipedia.org)
  • Along with Human coronavirus OC43 (a member of the Betacoronavirus genus), it is one of the viruses responsible for the common cold. (wikipedia.org)
  • The other six are: Human coronavirus NL63 (HCoV-NL63) Human coronavirus OC43 (HCoV-OC43) Human coronavirus HKU1 (HCoV-HKU1) Middle East respiratory syndrome-related coronavirus (MERS-CoV) Severe acute respiratory syndrome coronavirus (SARS-CoV-1) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Chloroquine, a zinc ionophore, inhibits the replication of Human coronavirus 229E in cell culture. (wikipedia.org)
  • domallei infections in Finnish tourists had a diagnosis of respiratory tract in- injured by the December 2004 tsunami fection ( 4 ). (cdc.gov)
  • Double or triple infections with HRV-C and respiratory syncytial virus and/or bocavirus were diagnosed in 33.3% of the HRV-infected patients, but no correlation with severity of clinical outcome was observed. (plos.org)
  • Earlier data demonstrate that populational Zn status is associated with the prevalence of respiratory tract infections in children and adults ( 6 , 7 ). (spandidos-publications.com)
  • Co-infections between viruses and bacteria were the most common (~69%), followed by viral-viral (~23%) and bacterial-bacterial (~7%) co-infections. (healthtrackrx.com)
  • Respiratory tract infections (RTIs) are one of the major public health concerns across the world. (healthtrackrx.com)
  • Human HCoV-229E, and human HCoV-NL63, likely originated from bats. (wikipedia.org)
  • 2. Suputtamongkol Y, Chaowagul W, Che- nal RNA copies per assay, respec- tchotisakd P, Lertpatanasuwun N, Inta- and severe acute respiratory syndrome ranongpai S, Ruchutrakool T, et al. (cdc.gov)
  • there is a single published case report to date of a 229E infection that caused acute respiratory distress syndrome (ARDS) in an otherwise healthy patient having no detectable co-infection with another pathogen. (wikipedia.org)
  • Given the increased interest for novel HRV strain identification and their worldwide distribution, we have carried out clinical and molecular diagnosis of HRV strains in a 2-year study of children with acute respiratory infection visiting one district hospital in Shanghai. (plos.org)
  • Few comprehensive data exist regarding the epidemiology of severe acute respiratory infec- tions (SARI) in low income countries. (123dok.net)
  • However, in vulnerable populations, such as newborns, infants, the elderly and immune-compromised individuals, these opportunistic pathogens can also affect the lower respiratory tract, causing a more severe disease (e.g., pneumonia). (mdpi.com)
  • This was an infection with much greater morbidity and mortality than previous viruses from the Coronaviridae family. (medscape.com)
  • Sixty-four HRV-infected outpatients were diagnosed amongst 827 children with acute low respiratory tract infection. (plos.org)
  • Respiratory syncytial virus (RSV) is the most frequent cause of lower respiratory tract infection in infants and children and the second most common viral cause of pneumonia in adults. (medscape.com)
  • Influenza pneumonia: Amantadine hydrochloride and rimantadine hydrochloride are approved for the prevention and treatment of influenza A virus infection. (medscape.com)
  • Improved Zn status may also reduce the risk of bacterial co‑infection by improving mucociliary clearance and barrier function of the respiratory epithelium, as well as direct antibacterial effects against S. pneumoniae. (spandidos-publications.com)
  • To investigate the epidemiological association of respiratory infection with viral load, HBoV-positive patients were categorized into low- and high-viral-load groups by using 1.0×106 copies/mL as a threshold value. (datexis.com)
  • Among the 17 HBoV-positive patients who were also positive for infection with other viruses, 10 showed PIV infection. (datexis.com)
  • These results suggest that single HBoV infection in the high-viral-load group may play an active role in respiratory infection. (datexis.com)
  • These findings are consistent with a Norwegian study that reported detection of HBoV alone and a high-viral-load were associated with respiratory tract infection. (datexis.com)
  • These findings also support the idea that a high-viral-load may be associated with a respiratory infection. (datexis.com)
  • Previous studies have reported that HBoV infection was more prevalent among individuals who had other respiratory viruses [10, 22]. (datexis.com)
  • This was followed after 3 to 7 days by the lower respiratory symptoms of cough, dyspnea, hypoxia, and respiratory failure in the more severe cases. (medscape.com)
  • The symptoms may worsen with time, and new respiratory signs and symptoms, such as dyspnea and cyanosis, appear. (medscape.com)
  • The influenza viruses are the most common viral cause of pneumonia. (medscape.com)
  • and Applied Biosystems™ TrueMark™ Respiratory Panel 2.0, TaqMan™ Array card (TAC) (41 viral, fungal, and bacterial targets). (healthtrackrx.com)
  • Interestingly, almost all cases (except two) positive for both HBoV and another respiratory virus belonged to the low-viral-load group. (datexis.com)
  • In our study, HBoV-positive patients in the high-viral-load group showed significantly higher pulse rates and respiratory rates than the in the low-viral-load group. (datexis.com)
  • None of the HRV-C strains appeared to have a higher clinical impact than HRV-A or HRV-B on respiratory compromise. (plos.org)
  • Signs and symptoms are flulike, and include primarily upper respiratory congestion, cough, and low-grade fever. (medscape.com)
  • COVID-19 first was identified during an outbreak of respiratory illness in Wuhan, the capital of Hubei province, China. (medscape.com)
  • I'm Dr Forest Arnold and welcome to Medscape's InDiscussion series on respiratory syncytial virus (RSV) in adults . (medscape.com)
  • As the virus culture was used for the detection of major respiratory viruses, the isolated virus could be the main causative agent of respiratory illness. (datexis.com)
  • molecular diagnostic methods were used for the detection of other respiratory viruses in the other studies whereas we used virus culturing. (datexis.com)
  • In a study performed in Hong Kong, a higher detection rate of HBoV was observed in NPAs positive for common respiratory viruses than in those that were negative for the same. (datexis.com)
  • However, in our study, similar detection rate of HBoV was observed in the samples positive and negative for other respiratory viruses in the R-mix culture (Data are not shown). (datexis.com)
  • Respiratory viruses can also exacerbate asthma and lead to various types of respiratory distress syndromes. (mdpi.com)
  • It is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the APN receptor. (wikipedia.org)
  • Integrated strategies for surveillance of COVID-19 and other respiratory viruses can further guide prevention efforts. (cdc.gov)
  • To describe U.S. RSV seasonality during prepandemic and pandemic periods, polymerase chain reaction (PCR) test results reported to the National Respiratory and Enteric Virus Surveillance System (NREVSS)* during July 2017-February 2023 were analyzed. (cdc.gov)
  • Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. (mdpi.com)
  • Nasopharyngeal swabs, sputum, and blood were collected from SARI patients enrolled and tested for viruses and bacteria. (123dok.net)
  • In view of the emerging COVID‑19 pandemic caused by SARS‑CoV‑2 virus, the search for potential protective and therapeutic antiviral strategies is of particular and urgent interest. (spandidos-publications.com)
  • It also caused severe respiratory disease, then essentially eradicated. (medscape.com)
  • The frequency of HBoV codetection with other respiratory viruses was 18.3% in the HBoV-positive samples and was lower than the previously published data [4, 20]. (datexis.com)
  • They also did a respiratory panel in which she tested positive for RSV. (medscape.com)
  • I recently saw a patient who had respiratory syncytial virus (RSV). (medscape.com)
  • Cytologic evaluation: Intranuclear inclusions often exist in cells infected with a deoxyribonucleic acid (DNA) virus. (medscape.com)