Nucleoside diphosphate sugars. Medical search. Frequent questions

It is also a precursor of the nucleotides adenosine monophosphate (AMP), adenosine diphosphate (ADP), and adenosine triphosphate (ATP). (inchikey.info)
These agents behave as antimetabolites that interact with a number of intracellular targets blocking the DNA chain elongation or interfering with biosynthesis of nucleosides and nucleotides, a limiting process in cell proliferation. (unicam.it)
D) Nucleotides are found in DNA, while nucleosides are found in RNA. (paragonlockandsafe.com)
Nucleotides 1" By Boris (PNG), SVG by Sjef - en:Image:Nucleotides.png (Public Domain) via Commons Wikimedia, Lakna, a graduate in Molecular Biology & Biochemistry, is a Molecular Biologist and has a broad and keen interest in the discovery of nature related things, Difference Between Nucleotide and Nucleoside, 3. (paragonlockandsafe.com)
Furthermore, nucleosides are good anticancer and antiviral substances while nucleotides are building blocks of DNA and RNA and some are energy molecules. (paragonlockandsafe.com)
It is formed either inside or on the surface of cells via the breakdown of nucleotides (the basic building blocks of DNA and RNA) or adenine phosphates: energy-rich adenosine triphosphate (ATP), adenosine diphosphate (ADP), and adenosine monophosphate (AMP). (natureknowsproducts.com)
Adenine nucleotides which contain deoxyribose as the sugar moiety. (jefferson.edu)
Nucleotides with a ribose sugar make up the RNA whereas those with a deoxyribose make up the DNA molecule. (biologyonline.com)
When the diet contains nucleotides, the body digests them by nucleotidases to produce nucleosides and phosphates. (biologyonline.com)
Cytidine, just as the other nucleosides, can give rise to nucleotides. (biologyonline.com)

C) Nucleosides contain only deoxyribose sugars. (paragonlockandsafe.com)
Based on the pentose sugar component, the nucleotide may either be a ribose or a deoxyribose . (biologyonline.com)
A nucleoside is a nucleobase with a five-carbon sugar (either ribose or deoxyribose). (biologyonline.com)
In contrast, deoxycytidine is a deoxyribonucleoside for having a sugar component that is deoxyribose . (biologyonline.com)
Definition noun plural: cytidines cy·ti·dine, ˈsaɪtɪdiːn A pyrimidine nucleoside that has cytosine attached to the pentose sugar ribose Details Overview A nucleoside is a nucleobase with a five-carbon sugar (either ribose or deoxyribose). (biologyonline.com)

A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. (lookformedical.com)
The HBP culminates in the production of an amino sugar uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) that, along with other charged nucleotide sugars, serves as the basis for biosynthesis of glycoproteins and other glycoconjugates. (biomedcentral.com)

Revisiting the Latency of Uridine Diphosphate-Glucuronosyltransferases (UGTs)-How Does the Endoplasmic Reticulum Membrane Influence Their Function? (mdpi.com)
Uridine diphosphate-glucuronosyltransferases (UGTs) are phase 2 conjugation enzymes mainly located in the endoplasmic reticulum (ER) of the liver and many other tissues, and can be recovered in artificial ER membrane preparations (microsomes). (mdpi.com)
Eventually, uridine diphosphate (UDP) and uridine triphosphate (UTP) are produced down the biosynthetic pathway by kinases and dephosphorylation of ATPs. (biologyonline.com)
The hexosamine biosynthetic pathway (HBP) and its end product uridine diphosphate N-acetyl glucosamine (UDP-GlcNAc) are important regulators of cell signaling that favor tumor promotion. (biomedcentral.com)
The hexosamine biosynthetic pathway utilizes up to 2-5% of glucose that enters a non-cancer cell and along with glutamine, acetyl-coenzyme A (Ac-CoA) and uridine-5′-triphosphate (UTP) are used to produce the amino sugar UDP-GlcNAc [ 5 ]. (biomedcentral.com)
This is then converted to GlcNAc-1P (N-acetylglucosamine 1-phosphate) by PGM3/AGM1 (phosphoglucomutase) and further to UDP-GlcNAc (uridine diphosphate N-acetylglucosamine) by UAP/AGX1 (UDP-N-acetylhexosamine pyrophosphorylase), utilizing UTP from the nucleotide metabolism pathway. (biomedcentral.com)

The simple sugar glucose can be metabolized to release some energy and store the rest as ATP (adenosine triphosphate). (ishinobu.com)
As for the nitrogenous base (or nucleobase) component, the common bases are adenine (A), guanine (G), cytosine (C), and uracil (U). Depending on the number of phosphates that make up the compound, the ribonucleotide may be designated as monophosphate (having only one phosphate group), diphosphate (having two phosphate groups), and triphosphate (having three phosphate groups). (biologyonline.com)
Cytidine can form cytidine monophosphate (CMP, i.e. cytidine with a single phosphate group), cytidine diphosphate (CDP, i.e. cytidine with two phosphate groups), and cytidine triphosphate (CTP, i.e. cytidine with three phosphate groups). (biologyonline.com)
It phosphorylates first to monophosphate form by a viral-encoded protein kinase homologue, and then to diphosphate and triphosphate forms by cellular kinases. (medscape.com)

This molecule is made of a nitrogen base (adenine), a ribose sugar, and three phosphate groups. (quick-advices.com)
Adenosine is a nucleoside that is composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety. (inchikey.info)
When the adenine is joined with a sugar molecule, it becomes a nucleoside called adenosine. (sciencing.com)
Phosphate groups link with the -OH group of 5 carbon of the sugar molecule. (paragonlockandsafe.com)
A glycosyltransferase that facilitates the transfer of a sialic acid sugar from a sialic acid-based activated sugar to another molecule. (cdghub.com)
These bonds are "high-energy" because the products of such bond breaking-adenosine diphosphate (ADP) and one inorganic phosphate group (P i )-have considerably lower free energy than the reactants: ATP and a water molecule. (umn.edu)

Esters formed between the aldehydic carbon of sugars and the terminal phosphate of guanosine diphosphate. (nih.gov)

Its nucleoside contains a purine base, i.e. an adenine attached to the ribose sugar. (quick-advices.com)
It is also a purine nucleoside.Adenosine belongs in all living cells and is an important component of RNA. (inchikey.info)

Adenosine diphosphate (ADP) is a nucleoside phosphate comprised of a ribonucleoside and two phosphate groups. (quick-advices.com)
It means it has a ribose as its sugar and two phosphate groups attached. (quick-advices.com)
The three phosphate groups, in order of closest to furthest from the ribose sugar, are alpha, beta, and gamma. (umn.edu)

dTDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase thymine. (wikipedia.org)
The biological results showed that the structure of 3'-Me-Ado is crucial for the antitumor activity of this type of ribose-modified nucleosides. (unicam.it)
Activated RNA nucleotide is another term for the mono RNA nucleotide which contains tri phosphate affixed to the ribose sugar backbone. (paragonlockandsafe.com)
A ribonucleotide is a nucleotide that has a ribose as its sugar component. (biologyonline.com)
Adenosine is a nucleoside consisting of the nitrogenous base adenine and a five-carbon sugar, ribose. (umn.edu)
Cytidine is a nucleoside consisting of cytosine and ribose sugar linked by β-N 1 -glycosidic bond. (biologyonline.com)
Cytidine is a ribonucleoside due to its ribose sugar. (biologyonline.com)

a pentose sugar and a nitrogenous base. (paragonlockandsafe.com)
A nucleoside is composed of a nitrogenous base and a pentose sugar. (paragonlockandsafe.com)
The nitrogenous base is bound to the 3′ position of the pentose sugar via a beta-glycosidic bond. (paragonlockandsafe.com)
The fundamental structure of a nucleotide is a nitrogenous base, a pentose sugar, and phosphate group(s). (biologyonline.com)

Simple sugars, carbohydrates which cannot be decomposed by hydrolysis . (lookformedical.com)
Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. (umbc.edu)

A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. (lookformedical.com)
Considerable progress has been made in the search for novel nucleoside structures with anticancer and/or antiviral activity by modifications in the nucleobase and/or in the sugar moiety and several branched-chain sugar nucleosides have shown potent antitumor activity. (unicam.it)
Deoxycytidine differs from cytidine by having a hydroxyl group replaced by hydrogen at the 2′ position of the sugar moiety. (biologyonline.com)

RNR is a multisubunit radical-containing enzyme involved in the conversion of ribonucleoside diphosphates to the corresponding 2'-deoxyribonucleotides, which are building blocks for DNA replication and repair. (unicam.it)

A modified colorimetric method for the estimation of N-acetyl amino sugars. (neglectedscience.com)
GLYCOSYLATION of other compounds with these amino sugars results in AMINOGLYCOSIDES. (lookformedical.com)

When phosphorylated by kinases, the nucleoside is converted into a nucleotide. (biologyonline.com)

A pyrimidine nucleoside is one in which the nucleobase is a pyrimidine, such as cytosine in cytidine. (biologyonline.com)

Thymidine diphosphate (TDP) or deoxythymidine diphosphate (dTDP) (also thymidine pyrophosphate, dTPP) is a nucleotide diphosphate. (wikipedia.org)
It is an ester of pyrophosphoric acid with the nucleoside thymidine. (wikipedia.org)
Unlike the other deoxyribonucleotides, thymidine diphosphate does not always contain the "deoxy" prefix in its name. (wikipedia.org)

Nucleoside analogues are a pharmacologically diverse family that includes cytotoxic compounds, antiviral agents and immunosuppressive molecules. (unicam.it)
Nucleoside and nucleotide analogues can be used in therapeutic drugs, include a range of antiviral products used to prevent viral replication in infected cells. (paragonlockandsafe.com)

In certain vital metabolic processes, AMP combines with inorganic phosphate to form ADP (adenosine diphosphate) and then ATP. (quick-advices.com)

Nucleosides such as cytidine can be produced by de novo synthesis pathways in the liver. (biologyonline.com)

Therefore, the dramatic changes of sugar type and concentration during the germination process undoubtedly regulates the enzyme activity and the pattern of gene expression of several enzymes [ 5 , 6 ]. (biomedcentral.com)
Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. (umbc.edu)

Sugars are the main source of carbon and energy, but they also have signaling functions [ 6 ]. (biomedcentral.com)
Nucleotide = Carbon sugar + Nitrogenous Base + Phosphate. (paragonlockandsafe.com)
Nucleoside = Carbon sugar + Nitrogenous Base. (paragonlockandsafe.com)

A nucleotide is a nucleoside with a phosphate ester linked to the sugar. (paragonlockandsafe.com)

The main difference between nucleotide and nucleoside is that nucleotide is the precursor of both DNA and RNA whereas nucleoside is the precursor of nucleotide. (paragonlockandsafe.com)

In recent years, several nucleoside RNR inhibitors have entered clinical trial or application such as arabinosylcytosine (ara-C), gemcitabine, cladribine, fludarabine and clofarabine. (unicam.it)
6. Nucleoside and nucleotide inhibitors are competitive substrate inhibitors that mimic the structure of a normal nucleotide but lack the 3′ hydroxyl group needed for the addition of the next nucleotide for DNA elongation. (paragonlockandsafe.com)
KP-1461 , a cytidine analogue belonging to the class of nucleoside reverse transcriptase inhibitors, has a potential use as a treatment for HIV/AIDS. (biologyonline.com)

A nucleoside differs from a nucleotide. (paragonlockandsafe.com)

When the stomach digests food, the carbohydrate (sugars and starches) in the food breaks down into another type of sugar, called glucose. (quick-advices.com)

A subunit of a larger biomolecule, e.g. a single amino acid in a protein or a specific sugar in an oligosaccharide. (cdghub.com)

Enables the transfer of a nucleotide-sugar from one side of a membrane to the other. (ntu.edu.sg)
A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. (ntu.edu.sg)

Nucleoside Nucleotide DNA RNA Oligonucleotide dTDP-glucose Coghill, Anne M. (wikipedia.org)

Their structures consist of sugar moitiess glycosidically bound to long-chain diols, triols, keto-ols and keto-diols. (gerli.com)

When a phosphate group links with a nucleoside, eventually it becomes a nucleotide. (paragonlockandsafe.com)

To our best knowledge, it is still unknown whether genome reduction could be used to optimize the production of chemicals such as nucleoside products. (biomedcentral.com)
These strains also have great potential for the production of other nucleosides and similar derived chemicals. (biomedcentral.com)

Seed germination is a crucial process in the plant life cycle when a dramatic variation of type and sugar content occurs just as the seed is hydrated. (biomedcentral.com)

Adenosine is an endogenous nucleoside found in every cell of the body. (natureknowsproducts.com)

The alkyl glucosides are highly effective surfactants in washing and cleansing agents but are also widely used in the cosmetic products sector, as auxiliaries in crop protection formulations and as surfactants in industrial cleansing agents and today can already be said to be the most important sugar surfactants based on the yearly production amounts. (gerli.com)
ADP stands for adenosine diphosphate, and it's not only one of the most important molecules in the body, it's also one of the most numerous. (sciencing.com)
Nucleotide and nucleoside are important molecules. (paragonlockandsafe.com)
However, nucleosides are also important in medicine since they have antica… Other parts like the sugar molecules and nitrogenous bases are common to both, nucleotide and nucleoside. (paragonlockandsafe.com)

This chemical also helps balance blood sugar levels, reduces inflammation and fat production, prevents insulin resistance, and controls body temperature and energy use. (natureknowsproducts.com)

A nucleoside diphosphate sugar which serves as a source of N-acetylgalactosamine for glycoproteins , sulfatides and cerebrosides. (lookformedical.com)

Glycoprotein formation in the Golgi and endoplasmic reticulum relies on the accumulation of nucleotide-conjugated sugars via the SLC35 family of transporters. (guidetopharmacology.org)

Organisms3

Chemicals and Drugs26

Phenomena and Processes3

Information Science2

Nucleotides10

Deoxyribose5

Biosynthesis2

Uridine6

Triphosphate4

Molecule6

Guanosine diphosphate1

Purine2

Phosphate groups3

Ribose7

Pentose sugar4

Hydrolysis2

Moiety3

Ribonucleoside1

Amino sugars2

Kinases1

Nucleobase1

Thymidine3

Analogues2

Inorganic phosphate1

Synthesis1

Enzymes2

Carbon3

Ester1

Precursor1

Inhibitors3

Differs1

Digests1

Protein1

Nucleotide sugar2

Glucose1

Structures1

Eventually1

Chemicals2

Occurs1

Cell1

Important4

Production1

Serves1

Family1