AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureInformation ScienceHealth Care
Nontuberculous MycobacteriaMycobacterium Infections, NontuberculousMycobacteriumMycobacterium InfectionsMycobacterium kansasiiMycobacterium tuberculosisMycobacterium chelonaeMycobacterium avium ComplexMycobacterium fortuitumMycobacterium avium-intracellulare InfectionMycobacterium marinumLymphadenitisMycobacterium xenopiMycobacterium aviumMycobacterium scrofulaceumSputumMycobacterium bovisTuberculosis, PulmonaryMycobacterium haemophilumTuberculosisSkin Diseases, BacterialMycobacterium smegmatisLung DiseasesDrinking WaterBacteriological TechniquesNucleic Acid ProbesDNA, BacterialChaperonin 60Antitubercular AgentsMycobacterium lepraeWater MicrobiologyPolymerase Chain ReactionRNA, Ribosomal, 16SBacterial ProteinsSensitivity and SpecificityTuberculin TestImmunocompetenceClarithromycinAntigens, BacterialCulture MediaMolecular Diagnostic TechniquesPolymorphism, Restriction Fragment LengthMycobacterium avium subsp. paratuberculosisBacterial Typing TechniquesSequence Analysis, DNAWater SupplyAnti-Bacterial AgentsSpecies SpecificityMicrobial Sensitivity TestsImmunocompromised HostReagent Kits, DiagnosticCystic FibrosisMycobacterium ulceransMycobacterium phleiMolecular Sequence DataEthambutolDNA, RibosomalIsoniazidClofazimineBCG VaccineMycolic AcidsRifampinTuberculosis, Lymph NodeBronchiectasisPrevalenceBase SequenceBathsMycobacterium lepraemuriumRifabutinGranulomaParatuberculosisRetrospective StudiesLeprosyInterferon-gammaSpondylitisTime FactorsEmpyema, TuberculousMycobacteriophagesTuberculosis, BovineDrug Resistance, Bacterial
Avium-intracellulareAbstractChelonaeInfections associated with heater-cooler devicesCaused by atypicalXenopiPulmonary disease causedIntracellulareComplexIsolationSpeciesLepraeFortuitumPrevalenceStrainsAtypical mycobacteriumFungiMicrobiologyCysticBronchiectasis2020EnvironmentalChimaeraGenavenseChronicClinicalSubspOpportunisticCausative agentPatientsIsolatesAntimicrobialGenusIdentificationGloballyMedianPathogensRespiratoryDiseaseWater
Avium-intracellulare3
  • Reports of the clinical efficacy of clarithromycin in patients with acquired immunodeficiency syndrome (AIDS) and Mycobacterium avium-intracellulare (MAI) complex have prompted its use in NTM lymphadenitis. (medscape.com)
  • Mycobacterium avium-intracellulare complex infections are becoming an increasing concern in veterinary medicine because they affect livestock, wildlife, and companion animals. (frontiersin.org)
  • Mycobacterium avium-intracellulare complex (MAC) infections are becoming an increasing concern in veterinary medicine because they occur in a wide range of animals, including domestic animals ( 1 ), ruminant and non-ruminant wildlife ( 2 ), and companion animals ( 3 , 4 ). (frontiersin.org)
Abstract1
Chelonae5
Infections associated with heater-cooler devices1
  • In the last few years, the FDA has focused on increasing awareness of Nontuberculous Mycobacteria (NTM) infections associated with heater-cooler devices and the subsequent risks to patients in health care facilities. (qlaboratories.com)
Caused by atypical2
  • Today, approximately 95% of mycobacterial cervical infections in adults are caused by Mycobacterium tuberculosis, and the remainder are caused by atypical mycobacterium, or nontuberculous mycobacterium (NTM). (medscape.com)
  • To this spectrum of pulmonary diseases caused by atypical mycobacteria, a new granulomatous disease process that has been referred to as "hot tub lung" has been described in the literature [ 11 - 13 ]. (ajronline.org)
Xenopi2
Pulmonary disease caused1
  • To critically review the literature describing the use of surgery in the treatment of pulmonary disease caused by nontuberculous mycobacteria (NTM). (ersjournals.com)
Intracellulare3
Complex16
Isolation3
  • Pulmonary Nontuberculous Mycobacteria, Canada persons with prior (1998-2000) NTM isolation. (cdc.gov)
  • Isolation of Nontuberculous Mycobacteria from Bovine Raw Lungs Bought in Butchers' Shops. (bvsalud.org)
  • The isolation of nontuberculous mycobacterias (NTM) has increased in recent years largely due to the use of liquid cultivation media. (isciii.es)
Species7
  • The introduction of new techniques, such as MALDI-ToF spectrometry, can identify a greater number of species of nontuberculous mycobacteria, as well as other types of slow-growing microorganisms having similarities with mycobacteria on cultural and morphological properties, which significantly increases the diagnostic capabilities of laboratories. (iimmun.ru)
  • In contrast, the MAC consists of several nontuberculous mycobacterial species, known as nontuberculous mycobacteria (NTM). (medicalnewstoday.com)
  • Mycobacterial species other than Mycobacterium tuberculosis and Mycobacterium leprae are classified as atypical mycobacteria, nontuberculous mycobacteria (NTM), or environmental mycobacteria. (medscape.com)
  • The type of disease depends on the species of mycobacteria, the route and degree of exposure, and the immune status of the host. (medscape.com)
  • Contact with different species of environmental Mycobacterium can cause acquired immunity to M. tuberculosis or increase the efficacy of BCG vaccine protection (M. vaccae, M. microti), although some species of these bacteria reduce the efficacy of BCG vaccine (M. scrofulaceum) [8,10-13]. (who.int)
  • Many species of mycobacteria exist. (msdmanuals.com)
  • The other mycobacteria species that cause disease are discussed here. (msdmanuals.com)
Leprae1
Fortuitum1
Prevalence2
  • We conducted a systematic review of the literature to estimate the burden (prevalence and incidence) of non-tuberculous mycobacteria in the cystic fibrosis population. (ersjournals.com)
  • The frequencies of environmental Mycobacterium in the low-prevalence area were much higher than in the high-prevalence area, perhaps due to different environmental factors. (who.int)
Strains1
  • 17 (21.8%) of microbial strains which have been identified using the method of DNA hybridization, identified by spectrometry, including slow-growing microorganisms, non-mycobacteria strains seven (9.0%): Gordonia rubriperticta, Nocardia forcinica, Tsukumurella spp. (iimmun.ru)
Atypical mycobacterium2
Fungi1
  • We also look for problems with unusual bacteria or fungi, and in the course of looking for fungi, we also found the nontuberculous mycobacteria. (cdc.gov)
Microbiology1
  • Microbiology of nontuberculous mycobacteria. (easybib.com)
Cystic4
  • Important paradigms of pulmonary disease with nontuberculous mycobacteria (NTM) are currently shifting based on an increasing attention within the field of cystic fibrosis (CF). These shifts are likely to benefit the management of all patients with pulmonary NTM, regardless of underlying pathology. (springer.com)
  • Announced as the most important emerging threat to cystic fibrosis (CF) patients at the 2013 European Cystic Fibrosis Conference, the perception of nontuberculous mycobacteria (NTM) disease has once again undergone a notable shift. (springer.com)
  • Background People living with cystic fibrosis have an increased risk of lung infection with non-tuberculous mycobacteria (NTM), which is reportedly increasing. (ersjournals.com)
  • [ 6 ] Person-to-person spread is extremely uncommon, although in 2012 the first known outbreak of respiratory Mycobacterium abscessus subsp massiliense disease occurring in a population of patients with cystic fibrosis (CF) was reported. (medscape.com)
Bronchiectasis2
  • The Laboratory of Chronic Airway Infection, led by Dr. Kenneth Olivier, focuses on bronchiectasis, a condition that damages the body's ability to clear mucus from the airways and increases risk of severe lung infections by nontuberculous mycobacteria (NTM), which commonly are found in wet environments such as streams, rivers, and marshes. (nih.gov)
  • Dr. Olivier's research focuses on bronchiectasis , a condition that damages the body's ability to clear mucus from the airways and increases risk of severe lung infections by nontuberculous mycobacteria (NTM), which commonly are found in wet environments such as streams, rivers, and marshes. (nih.gov)
20201
  • Retrospective analysis (2015-2020) of a comprehensive database was conducted including all results of cultures for mycobacteria in a University Hospital (Geneva, Switzerland), covering a population of approximately 500,000 inhabitants. (unige.ch)
Environmental6
  • Nontuberculous mycobacteria (NTM), also known as environmental mycobacteria, atypical mycobacteria and mycobacteria other than tuberculosis (MOTT), are mycobacteria which do not cause tuberculosis or leprosy (also known as Hansen's disease). (wikipedia.org)
  • NTM are also referred to as atypical mycobacteria, mycobacteria other than tuberculosis (MOTT), or environmental mycobacteria. (cdc.gov)
  • The different environmental mycobacteria are very similar and for many years were mistakenly assumed to be M. tuberculosis in patients [1,2]. (who.int)
  • However, the relative incidence of the environmental Mycobacterium spp. (who.int)
  • Another reason for the medical importance of environmental Mycobacterium is the potential impact on the immune response. (who.int)
  • And in the environmental samples, like basic water and soil samples, a variety of non-tuberculous mycobacteria were found at the time. (hstalks.com)
Chimaera5
  • The Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) are investigating reports that a device used to heat and cool the blood during surgery has been linked to a rare bacterial infection caused by Mycobacterium chimaera , a type of bacteria known as nontuberculous mycobacterium (NTM). (cooperhealth.org)
  • Invasive infections with Mycobacterium chimaera were reported in patients with previous open chest surgery and exposure to contaminated heater-cooler units (HCUs). (eurosurveillance.org)
  • Prolonged Outbreak of Mycobacterium chimaera Infection After Open-Chest Heart Surgery. (eurosurveillance.org)
  • Healthcare-associated prosthetic heart valve, aortic vascular graft, and disseminated Mycobacterium chimaera infections subsequent to open heart surgery. (eurosurveillance.org)
  • Sommerstein R , Rüegg C , Kohler P , Bloemberg G , Kuster SP , Sax H . Transmission of Mycobacterium chimaera from heater-cooler units during cardiac surgery despite an ultraclean air ventilation system. (eurosurveillance.org)
Genavense1
  • And probably many of them were non-tuberculous mycobacteria, as they were found in a lot of animals that we now know harbor some non-tuberculous mycobacteria, like birds that are known to carry mycobacterium avium and mycobacterium genavense. (hstalks.com)
Chronic2
Clinical2
  • Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline. (nih.gov)
  • Clinical relevance of nontuberculous Mycobacteria . (isciii.es)
Subsp2
Opportunistic2
  • Nontuberculous mycobacteria (NTM) have emerged as critical opportunistic pathogens of lung diseases recently. (nih.gov)
  • Nontuberculous Mycobacteria (NTM) can cause opportunistic disease in animals and humans , causing mycobacteriosis. (bvsalud.org)
Causative agent2
Patients4
  • Survival implications of nontuberculous mycobacterial pul- generalized to all NTM-PD patients. (cdc.gov)
  • The first involved finding the nontuberculous mycobacteria and treating the patients. (cdc.gov)
  • Minimal resection surgery, in a carefully selected subgroup of patients with focal disease or persistent symptoms can be considered as an adjuvant therapy in the treatment of pulmonary nontuberculous mycobacterium infection. (ersjournals.com)
  • L'objectif de la présente étude conduite en Égypte était d'évaluer l'utilité d'un test de quantification de la libération d'interféron gamma (IFN-) pour le dépistage des infections tuberculeuses latentes chez les contacts de patients atteints de tuberculose active. (who.int)
Isolates1
  • For non-tuberculous mycobacteria ( NTM ), minimum inhibitory concentration ( MIC ) distributions of wild-type isolates have not been systematically evaluated despite their importance for establishing antimicrobial susceptibility testing ( AST ) breakpoints. (sciensano.be)
Antimicrobial1
Genus2
  • Belonging to the same genus, Mycobacteria, they also share some features. (medicalnewstoday.com)
  • The family Mycobacteriaceae consists of a single genus, Mycobacterium , which are thin, slightly curved-to-straight, non-spore-forming, nonmotile acid-fast bacilli. (medscape.com)
Identification1
  • Due to this rather limited possibility of identification of non-tuberculous mycobacteria, using a DNA-hybridization method is inadequate to date. (iimmun.ru)
Globally1
  • The incidence of nontuberculous mycobacterial (NTM) infection has been increasing globally. (degruyter.com)
Median1
  • Mycobacteria (median = 658 CFU/m 2 ) were positively associated with asthma symptoms (OR = 1.5, 95% CI = 0.97-2.43). (nih.gov)
Pathogens1
  • Nontuberculous mycobacteria (NTM) are increasingly identified in industrialized countries, and their role as pathogens is more frequently recognized. (unige.ch)
Respiratory1
  • Thermophilic actinomycetes and non-tuberculous mycobacteria may have played a role in the occupants' respiratory outcomes in this water-damaged building. (nih.gov)
Disease4
  • Medical treatment of pulmonary nontuberculous mycobacteria (NTM) disease has highly variable outcomes. (ersjournals.com)
  • Disease-causing microorganisms found in untreated dental unit water can include Legionella, Pseudomonas aeruginosa , and nontuberculous Mycobacteria (NTM). (cdc.gov)
  • It was only in the first five decades of the last century that sporadic case reports of disease caused by these atypical mycobacteria started to emerge. (hstalks.com)
  • So in 1953, Buhler and Pollak for the first time recorded clear-cut lung disease caused by a non-tuberculous mycobacterium. (hstalks.com)
Water3
  • Multiple outbreaks of nontuberculous Mycobacteria (NTM) infections have occurred in children who received pulpotomies in pediatric dental clinics where the dental treatment water contained high levels of bacteria. (cdc.gov)
  • Microbial testing of the water samples taken from the dental units showed very high microbial counts of Mycobacterium abscessus . (cdc.gov)
  • The infection is usually caused by eating soil or drinking water that is contaminated with the mycobacteria. (msdmanuals.com)