OrganismsDiseasesChemicals and DrugsPhenomena and ProcessesInformation ScienceHealth Care
NocardiaNocardia InfectionsNocardia asteroidesMycetomaRNA, Ribosomal, 16SDNA, RibosomalMycolic AcidsEncyclopedias as TopicTemperaturePeriodontal PocketSulfuric Acids
FarcinicaNocardiosisCyriacigeorgicaInfectionsGenusBrasiliensisInfectionAbscessesPathogenicBacteriaAbscessusOtitidiscaviarumPulmonaryActinomycesAbstractWeaklyIsolatesAerobicIsolationMycobacteriaActinomaduraValidly describedClinicalStaphylococcusCharacteristicsOrganismsMycetomaOpportunistic pathogenSoilStrainsMicroorganismsAntimicrobialMicroscopicDiagnosisDiseaseColoniesIdentificationRespiratoryCulture
Farcinica5
  • The most commonly encountered species are Nocardia brasiliensis, Nocardia cyriacigeorgica, Nocardia farcinica, and Nocardia nova. (wikipedia.org)
  • The complete genomic sequence of Nocardia farcinica IFM 10152. (nih.gov)
  • Nocardia cyriacigeorgica, N. farcinica, and N. nova were separated from the Nocardia asteroides complex and Nocardia pseudobrasiliensis from Nocardia brasiliensis. (antimicrobe.org)
  • We present the first reported case of a child with cystic fibrosis harboring Nocardia farcinica. (mssm.edu)
  • Disseminated Nocardia farcinica infection presenting as a paravertebral abscess in a patient with systemic lupus erythematosus. (medscape.com)
Nocardiosis7
  • Nocardia is capable of causing a variety of infections, including pulmonary nocardiosis, central nervous system (CNS) infection, cutaneous disease and bloodstream infection (BSI). (biomedcentral.com)
  • Nocardia, nocardiosis and mycetoma. (medscape.com)
  • No human-to-human of nocardiosis were defined as any case transmission has been documented so far with culture-proven Nocardia spp. (who.int)
  • Nocardiosis is an infection caused by several species of soil-borne aerobic bacteria belonging to the genus Nocardia . (medscape.com)
  • Disseminated nocardiosis is responsible for most occurrences of nocardiosis, is most commonly caused by Nocardia asteroides , and typically affects immunocompromised hosts, although individuals with presumed immunocompetency also can develop the disease. (medscape.com)
  • Primary cutaneous nocardiosis, most commonly caused by Nocardia brasiliensis , typically affects immunocompetent individuals with a history of trauma and can be subdivided into 3 clinical entities that include (1) lymphocutaneous infection, (2) mycetoma, and (3) superficial skin infection, including ulceration, abscess, and cellulitis. (medscape.com)
  • Nocardia species also cause infections in animals, including bovine mastitis and sporotrichoid nocardiosis in horses. (medscape.com)
Cyriacigeorgica5
  • Nocardia cyriacigeorgica (4/12) was more frequently occurring in ND, followed by Nocardia abscessus (3/12). (biomedcentral.com)
  • Browne W D, Lieberson R E, Kabbesh M J (November 08, 2021) Nocardia cyriacigeorgica Brain and Lung Abscesses in 77-Year-Old Man With Diabetes. (kabbesh.com)
  • Recently, the number of diagnoses of Nocardia cyriacigeorgica has grown in the United States, yet complicated clinical diagnosis and costly identification methods make us presume an underestimation of its presence in patients. (kabbesh.com)
  • Nocardia cyriacigeorgica is difficult to identify and differentiate from nontuberculous mycobacteria using conventional methods making clinical diagnosis elusive [1-3] . (kabbesh.com)
  • Brain abscess due to Nocardia cyriacigeorgica simulating an ischemic stroke. (medscape.com)
Infections11
  • clarification needed] Most Nocardia infections are acquired by inhalation of the bacteria or through traumatic introduction. (wikipedia.org)
  • Nocardia may also cause a variety of cutaneous infections such as actinomycetoma (especially N. brasiliensis), lymphocutaneous disease, cellulitis, and subcutaneous abscesses. (wikipedia.org)
  • People who take trimethoprim-sulfamethoxazole for other reasons, such as prevention of Pneumocystis jirovecii infection, appear to have fewer Nocardia infections, although this protective effect has been considered unreliable, and some studies have disputed it altogether. (wikipedia.org)
  • Since Nocardia species infections are very often sporadic, information from randomized clinical trials comparing the clinical efficacy of specific antimicrobial agents is lacking. (antimicrobe.org)
  • Nocardia asteroides is responsible for the majority of infections in humans. (am-online.org)
  • This review will compare and contrast infections due to Actinomyces and Nocardia. (qxmd.com)
  • Nocardia are non-motile, Gram-positive, partially acid-fast bacilli, most commonly responsible for lung, brain, and skin infections in immunocompromised hosts including those with acquired immunodeficiency syndrome (AIDS), cancer, lupus, and diabetes. (kabbesh.com)
  • Trimethoprim-sulfamethoxazole therapy for Nocardia infections. (medscape.com)
  • Manifestations and outcomes of nocardia infections: Comparison of immunocompromised and nonimmunocompromised adult patients. (medscape.com)
  • Castro JG, Espinoza L. Nocardia species infections in a large county hospital in Miami: 6 years experience. (medscape.com)
  • Nocardia asteroides usually causes lung and bodywide infections. (msdmanuals.com)
Genus10
  • Nocardia is a genus of weakly staining Gram-positive, catalase-positive, rod-shaped bacteria. (wikipedia.org)
  • Data derived from modern taxonomic methods have changed the taxonomy of the genus Nocardia ( 27 ). (antimicrobe.org)
  • The genus Nocardia is currently composed of 87 validly described species: 46 of these species are medically relevant ( 16 , 27 , 53 ). (antimicrobe.org)
  • The presence of aerial filaments, decomposition of substrates, and acid production from or carbon utilization of carbohydrates, as previously described, are used to differentiate the members of the genus Nocardia ( 8 , 27 , 55 ). (antimicrobe.org)
  • A soil isolate representing the putatively novel species 'Nocardia uniformis' was found to have morphological, staining and chemotaxonomic properties consistent with its classification in the genus Nocardia. (ncl.ac.uk)
  • The genotypic and phenotypic data indicate that the strain should be assigned to the genus Nocardia as a new species. (ncl.ac.uk)
  • Clinical records, laboratory finding, CT images and mNGS results were reviewed for 19 patients who were positive for Nocardia genus. (biomedcentral.com)
  • Similar to anaerobic organisms of the genus Actinomyces , Nocardia species often form thin filaments that can resemble but are much thinner than those of true fungi (1-2 µm vs 3-5 µm in diameter). (medscape.com)
  • Members of the genus Nocardia are aerobic actinomycetes that are ubiquitous saprophytes in soil, decaying organic matter, and fresh and salt water. (medscape.com)
  • Over 100 species of the genus Nocardia have been identified, more than half of which have been described during the last decade. (medscape.com)
Brasiliensis1
  • strain NRRL 5646, a species most closely related to Nocardia brasiliensis strain DSM 43758T. (canada.ca)
Infection12
  • In about 25-33% of people Nocardia infection takes the form of encephalitis and/or brain abscess formation. (wikipedia.org)
  • In most patients with Nocardia infection, the combination of antibiotics is needed.Antibiotic therapy with a sulfonamide, most commonly trimethoprim-sulfamethoxazole, is the treatment of choice. (wikipedia.org)
  • Nocardia puris is a rare cause of infection worldwide, with very few published cases. (microbiologyresearch.org)
  • Pulmonary infection with Nocardia species: a report of 10 cases and review. (microbiologyresearch.org)
  • As the unspecifc clinical presentation and low identification rate of the culture dependent methods, Nocardia infection may be under-diagnosis. (biomedcentral.com)
  • Lung cancer patient with Tropheryma whipplei and Nocardia co-infection. (qxmd.com)
  • Although TW infection has been reported in cancer patients, co-infection with Nocardia is a unique occurrence in this case. (qxmd.com)
  • Opportunistic pathogens are common in immunocompromised patients but in this case, the patient was a young adult with normal immunity and an early-stage tumor with TW and Nocardia co-infection. (qxmd.com)
  • In a recent case report published in the U.S. Centers for Disease Control and Prevention's (CDC) journal Emerging Infectious Diseases, researchers reported a case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Nocardia pseudobrasiliensis concomitant infection. (news-medical.net)
  • Secular trends of nocardia infection over 15 years in a tertiary care hospital. (medscape.com)
  • Au total, on a établi que 19 sujets étaient atteints d'une infection à Nocardia confirmée par culture. (who.int)
  • They inhale dust that contains Nocardia bacteria, resulting in a lung infection. (msdmanuals.com)
Abscesses1
  • The differential diagnosis of pulmonary nodules in patients with HIV is broad and includes TBC, nocardia which is usually associated with skin lesions that look like nodules and abscesses, and fungal pathogens including histoplasma, paracoccidiodomycosis and cryptococcus Pneumocystosis rarely presents with nodules. (uab.edu)
Pathogenic2
  • Nocardia species are deeply involved in the process of encephalitis as one of its main pathogenic effects. (wikipedia.org)
  • Nocardia otitidiscaviarum is a rare opportunistic pathogen and is believed less pathogenic than the more common species of Nocardia. (thelabrat.com)
Bacteria5
  • Bacteria that masquerade as fungi: actinomycosis/nocardia. (qxmd.com)
  • Nocardia species are ubiquitous groups of gram-positive environmental bacteria which were initially reported in 1888 [ 1 , 2 ]. (biomedcentral.com)
  • Nocardia bacteria can infect the lungs when they are inhaled, and they can infect the skin when they enter the skin through a cut or scrape. (msdmanuals.com)
  • Nocardia bacteria can spread to nearby tissue or through the bloodstream to infect any organ. (msdmanuals.com)
  • When observed microscopically, either in Gram-stained smears of clinical specimens or cultures or on histopathology in tissues, Nocardia organisms are branching, beaded, filamentous, gram-positive bacteria with a characteristic morphology to a trained observer. (medscape.com)
Abscessus1
Otitidiscaviarum6
  • Nocardia otitidiscaviarum has been isolated in pure culture from activated sludge. (thelabrat.com)
  • Nocardia otitidiscaviarum was reclassified from Nocardia caviae . (thelabrat.com)
  • Nocardia otitidiscaviarum is thought to be responsible for a number of Actinomycetoma Pedis cases in India. (thelabrat.com)
  • The organism was consistently associated with the type strain of Nocardia otitidiscaviarum albeit with a relatively low bootstrap value recorded for neighbour-joining analysis. (ncl.ac.uk)
  • Pleural effusion-related Nocardia otitidiscaviarum, Anaplasma platys and Ehrlichia canis coinfection in a dog. (bvsalud.org)
  • Here, we report for the first time a triple coinfection by Nocardia otitidiscaviarum, A. platys, and E. canis in a dog with pleural effusion , where debilitating or immunosuppressive conditions induced by A. platys and E. canis coinfection probably contributed to the opportunistic behavior of N. otitidiscaviarum. (bvsalud.org)
Pulmonary1
  • Pre-existing pulmonary disease, especially pulmonary alveolar proteinosis, increases the risk of contracting a Nocardia pneumonia. (wikipedia.org)
Actinomyces1
  • Both Actinomyces and Nocardia cause similar clinical syndromes involving the lung, bone and joint, soft tissue, and the central nervous system. (qxmd.com)
Abstract1
Weakly2
  • Since Nocardia are weakly acid fast, the most useful acid-fast stain is the modified Kinyoun method ( 33 , 55 ). (antimicrobe.org)
  • Nocardia are typically weakly acid-fast after traditional staining and positive on modified acid-fast staining, but this is not invariable. (medscape.com)
Isolates5
  • Sulfonamide resistance in isolates of Nocardia spp. (microbiologyresearch.org)
  • Multicenter study in Taiwan of the in vitro activities of nemonoxacin, tigecycline, doripenem, and other antimicrobial agents against clinical isolates of various Nocardia species. (microbiologyresearch.org)
  • There have been a few reports of these organisms isolated from cystic fibrosis patients and, when recovered, the isolates were almost always Nocardia asteroides. (mssm.edu)
  • Fifty-four clinical isolates of Nocardia spp. (elsevierpure.com)
  • Antigens were prepared from (M-faeni), Aspergillus-fumigatus (A-fumigatus), Thermoactinomycetes-vulgaris (T-vulgaris) and Thermoactinomycetes- candidus (T-candidus) and from moldy hay isolates of four strains of T-vulgaris and two strains of thermophilic Nocardia. (cdc.gov)
Aerobic2
  • Antimicrobial susceptibility testing and profiling of Nocardia species and other aerobic actinomycetes from South Africa: comparative evaluation of broth microdilution versus the Etest. (microbiologyresearch.org)
  • Nocardia species are difficult to identify, saprophytic, aerobic actinomycetes that are associated with high mortality rates and primarily affect immunocompromised hosts. (kabbesh.com)
Isolation3
  • Nocardia isolation from biological specimens can be performed using an agar medium enriched with yeast extract and activated charcoal (BCYE), the same used for Legionella species. (wikipedia.org)
  • A definitive diagnosis depends on the isolation and the identification of Nocardia species. (antimicrobe.org)
  • The definitive diagnosis of nocardial disease depends on isolation and culture of Nocardia from suspected sites [ 4 ]. (biomedcentral.com)
Mycobacteria1
  • Performance Standards for Susceptibility Testing of Mycobacteria, Nocardia spp. (clsi.org)
Actinomadura1
  • Under a magnification of 600X, this photomicrograph of a tissue specimen, excised from an actinomycotic mycetoma, and stained using the hematoxylin-eosin (H&E) method, revealed histopathologic changes, due to the organism, Actinomadura pelletieri , formerly known as Nocardia pelletieri . (cdc.gov)
Validly described1
  • The strain was also readily separated from representatives of all validly described Nocardia species using a set of phenotypic properties. (ncl.ac.uk)
Clinical1
Staphylococcus1
  • Organisms that are catalase negative are killed normally, whereas catalase-positive organisms (Staphylococcus aureus, Aspergillus, Nocardia, and Serratia) cause major problems. (lu.se)
Characteristics1
Organisms2
  • Nocardia is a sort of microscopic organisms that is a strange reason for contamination. (newjerseytimes.us)
  • Photomicrograph of tissue biopsy stained with Gomori methenamine silver demonstrating acute inflammatory response and organisms compatible with Nocardia. (medscape.com)
Mycetoma1
Opportunistic pathogen1
  • As an opportunistic pathogen, Nocardia often occurring in the immunocompromised hosts. (biomedcentral.com)
Soil2
  • Nocardia species are found worldwide in soil rich in organic matter. (wikipedia.org)
  • Nocardia is found in the dirt, and houseplants are known wellsprings of the irresistible soil. (newjerseytimes.us)
Strains1
  • Alignment of 386 bp of the sodA (A) and 468 bp of the secA1 genes (B) of the patient's isolate (strain EML 1879) with the sodA and secA1 genes sequences of a set of reference strains of Nocardia species according to the Sánchez-Herrera's instructions ( 5 ). (cdc.gov)
Microorganisms1
  • Nocardia microorganisms are filamentous rods that show right-angled branching both in culture and in tissues. (antimicrobe.org)
Antimicrobial1
  • Nocardia identification is of paramount importance as it is not treated with empiric antimicrobial therapy. (archivosdeneurociencias.org)
Microscopic1
  • High-power microscopic appearance of Nocardia. (medscape.com)
Diagnosis1
  • Recent study have reported physicians could benefit from metagenomic next-generation sequencing (mNGS) in Nocardia diagnosis. (biomedcentral.com)
Disease2
  • Nocardia asteroides is most frequently found species causing noncutaneous invasive disease. (wikipedia.org)
  • The vast majority with nocardia disease have debilitated safe frameworks, for example, by HIV, diabetes, malignant growth or medications that smother the insusceptible framework. (newjerseytimes.us)
Colonies1
  • Nocardia colonies have a variable appearance, but most species appear to have aerial hyphae when viewed with a dissecting microscope, particularly when they have been grown on nutritionally limiting media. (wikipedia.org)
Identification4
  • 2. Rodríguez-Nava V, Couble A, Devulder G, Flandrois JP, Boiron P, Laurent F. Use of PCR-restriction enzyme pattern analysis and sequencing database for hsp65 gene-based identification of Nocardia species. (cdc.gov)
  • Analysis of secA1 gene sequences for identification of Nocardia species. (cdc.gov)
  • The use of molecular technology for identification and epidemiologic subtyping of the Nocardia species has been limited by the lack of simple and rapid assays. (antimicrobe.org)
  • Identification of Phenol-Degrading Nocardia Sp. (researchgate.net)
Respiratory1
  • Nocardia bacteremia is less often encountered and it has often concurrent other infected site, such as respiratory tract and skin [ 2 ]. (biomedcentral.com)
Culture2
  • Nocardia grow slowly on nonselective culture media, and are strict aerobes with the ability to grow in a wide temperature range. (wikipedia.org)
  • Culture for nocardia was negative. (uab.edu)