Cyclic Nucleotide Phosphodiesterases, Type 13',5'-Cyclic-AMP PhosphodiesterasesCyclic Nucleotide Phosphodiesterases, Type 5Cyclic Nucleotide Phosphodiesterases, Type 4Cyclic Nucleotide Phosphodiesterases, Type 3Cyclic Nucleotide Phosphodiesterases, Type 23',5'-Cyclic-GMP PhosphodiesterasesPhosphoric Diester Hydrolases2',3'-Cyclic-Nucleotide PhosphodiesterasesNucleotides, CyclicPhosphodiesterase InhibitorsCyclic GMPCyclic Nucleotide Phosphodiesterases, Type 7Cyclic AMPPurinonesRolipram1-Methyl-3-isobutylxanthineNitric OxideIsoenzymesNitric Oxide SynthaseMolecular Sequence DataCalmodulinAmino Acid SequenceKineticsCyclic Nucleotide Phosphodiesterases, Type 6Nitric Oxide Synthase Type IINitric Oxide DonorsNucleotidesNitric Oxide Synthase Type IIINitric Oxide Synthase Type IGuanylate CyclasePhosphodiesterase 3 InhibitorsCyclic GMP-Dependent Protein KinasesPhosphodiesterase 4 InhibitorsEnzyme Inhibitors4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinoneDibutyryl Cyclic GMPTheophyllineCells, CulturedNG-Nitroarginine Methyl EsterCyclic Nucleotide-Gated Cation ChannelsSignal TransductionPhosphodiesterase IArginineMilrinoneNitroprussideSecond Messenger SystemsBucladesinePhosphorus-Oxygen LyasesBase SequenceNitritesCyclic AMP-Dependent Protein KinasesAdenine NucleotidesPyrrolidinonesCattleRNA, MessengerAdenylate CyclaseDose-Response Relationship, DrugEnzyme ActivationCalciumPhosphodiesterase 5 Inhibitorsomega-N-MethylarginineCell LineHydrolysisRats, Sprague-DawleyCyclic IMPColforsinPapaverineCloning, Molecular8-Bromo Cyclic Adenosine MonophosphateEndothelium, VascularBinding SitesS-Nitroso-N-AcetylpenicillamineMutationGene Expression Regulation, EnzymologicSubstrate SpecificityNitratesProtein BindingAmino Acid OxidoreductasesTime FactorsRats, WistarPolymorphism, Single NucleotideIsoproterenolProtein Structure, TertiaryVasodilator AgentsNitrogen OxidesPenicillamineProteasome Endopeptidase ComplexCatalytic DomainPhosphorylationGuanine NucleotidesSequence Homology, Amino AcidVasodilationXanthinesVinca AlkaloidsOxidesSulfonesPurinesMyocardiumModels, Molecular