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  • bind
  • In line, HBsAg preferentially bound to TLR9-triggered pDC demonstrating that once pDC are able to bind HBV/HBsAg, the virus exerts its immune regulatory effect. (jove.com)
  • cells
  • Due to the relatively conserved binding region of E2 to the CD81 receptor on the liver cells, this discovery is expected to pave the way to design a HCV vaccine which will stimulate antibody response with neutralizing effects on broad range of virus strains. (wikipedia.org)
  • andsubsequently administering at least once a second composition comprising a viral vector comprising a nucleic acid encoding said at least one epitope of said first composition, whereby the nucleic acid of said second composition is expressed in one or more cells of the subject and at least part of the protein of said first composition is produced. (patentsencyclopedia.com)
  • present
  • In particular, about 60% of HCV-infected patients present cold-precipitable (cryoprecipitable) and noncryoprecipitable immune complexes that could be associated with the clinical onset of type II mixed cryoglobulinemia (MCII) [ 2 ]. (mdpi.com)
  • The methods utilize one or more administrations of HCV protein compositions, followed by one or more administrations of a viral vector comprising a nucleic acid encoding a least one HCV epitope that is present in the first composition. (patentsencyclopedia.com)
  • contain
  • Negative-stain electron microscopy revealed that the particles were spherical (~40- to 75-nm diameter) and pleomorphic and that some of them contain HCV E2 protein and apolipoprotein E on their surfaces. (pubmedcentralcanada.ca)