• To assess the causal relation between acute mental stress and myocardial ischemia, we evaluated cardiac function in selected patients during a series of mental tasks (arithmetic, the Stroop color--word task, simulated public speaking, and reading) and compared the responses with those induced by exercise. (nih.gov)
  • Personally relevant mental stress may be an important precipitant of myocardial ischemia--often silent--in patients with coronary artery disease. (nih.gov)
  • Further examination of the pathophysiologic mechanisms responsible for myocardial ischemia induced by mental stress could have important implications for the treatment of transient myocardial ischemia. (nih.gov)
  • Among patients with diabetes and without known coronary artery disease and referred for myocardial perfusion imaging, 12.7% had significant ischemia, and 60% had reduced myocardial blood flow reserve (MBFR) including those without symptoms of ischemia. (medscape.com)
  • In this article, we presented a case of giant coronary aneurysm involving right coronary artery with associated asymptomatic myocardial ischemia as evident by multimodality imaging. (thieme-connect.com)
  • The diagnosis should exclude other overt causes that might cause troponin elevation, like sepsis or pulmonary embo-lism, Takotsubo syndrome or myocardial cell injury that is not related to ischemia (eg: myocarditis)2. (romanianjournalcardiology.ro)
  • In an important prospective study in the Canadian Journal of Cardiology , published by Elsevier, investigators report that attending a multidisciplinary dedicated women's heart center can increase the likelihood of an accurate diagnosis and significantly improve clinical and psychological outcomes of women reporting chest pain due to insufficient heart-muscle blood flow (myocardial ischemia) but not diagnosed with obstructive coronary artery disease. (eurekalert.org)
  • Ischemia with no obstructive coronary artery disease (INOCA) may affect up to 62% of women undergoing coronary angiography for suspected angina, with a higher prevalence in mid-life women aged 45-65 years. (eurekalert.org)
  • Many women with cardiac chest pain and ischemia or heart attack have no significant blockages of their larger coronary arteries but can have narrowing or dysfunction of their small coronary vessels or spasm of their blood vessels, which may be missed at initial diagnosis. (eurekalert.org)
  • 1 Coronary artery disease can lead to inadequate tissue oxygenation, a state known as ischemia. (cms.gov)
  • This retrospective, observational study included 2730 consecutive patients with diabetes and without known coronary artery disease treated in a large health system in the bi-state Kansas City metro area during 2010-2016 who underwent pharmacologic rest/stress myocardial perfusion imaging (MPI) using rubidium-82 positron emission tomography . (medscape.com)
  • We assessed the incremental prognostic value of heart rate reserve (HRR) over stress myocardial perfusion single-photon emission computed tomography (MPS) findings in patients with suspected coronary artery disease (CAD). (unina.it)
  • Wall motion (WM), Doppler-derived measurement of the coronary flow reserve (CFR) in the left anterior descending coronary artery (LAD), and myocardial perfusion imaging (MPI) can be sequentially assessed during dipyridamole stress echocardiography. (thoracickey.com)
  • During the past decade, stress echocardiography (SE) has moved beyond the standalone analysis of wall motion (WM), thanks to the clinical feasibility of both Doppler-derived measurement of coronary flow reserve (CFR) in the left anterior descending coronary artery (LAD) and contrast myocardial perfusion imaging (MPI). (thoracickey.com)
  • Positron Emission Tomography (PET) is considered to have the highest accuracy for the assessment of myocardial perfusion in patients with suspected coronary artery disease (CAD), but its long-term prognostic accuracy in women has not been established. (uzh.ch)
  • Myocardial perfusion imaging and coronary artery disease : recent technological innovations]. (bvsalud.org)
  • Innovations technologiques récentes en scintigraphie de perfusion myocardique et maladie coronarienne. (bvsalud.org)
  • 9 Luckraz H, Parums DV, Dunning J. Reverse saphenous interposition vein graft repair of a giant atherosclerotic aneurysm of the left anterior descending coronary artery. (thieme-connect.com)
  • In interviews with medical personnel in hurricane-affected areas, a leading concern expressed was the urgency of treating people with chronic diseases such as diabetes, cardiovascular disease, hypertension, and kidney disease. (cdc.gov)
  • data to study the association between cardiovascular fitness and other health conditions and risk factors, such as obesity, cardiovascular disease, diabetes, hypertension, and activity and dietary patterns. (cdc.gov)
  • Chronotropic incompetence is common in patients with cardiovascular disease and is associated with increased risk of adverse events. (unina.it)
  • 2. Phase in a mandatory wellness/fitness program for FFs to reduce risk factors for cardiovascular disease and improve cardiovascular capacity. (cdc.gov)
  • Randomised trials of vitamin D supplementation for cardiovascular disease and all-cause mortality have generally reported null findings. (nih.gov)
  • Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. (nature.com)
  • Cardiovascular disease (CVD) continues to be a leading cause of hospitalization and death in women. (eurekalert.org)
  • Since 2010, over 60 entities including 40 new firms globally have set out to capitalise on these technological advances, seeking to commercialise AI-based diagnostics services in fields such as cancer and cardiovascular disease (CVD). (idtechex.com)
  • Furthermore, inactivating variants in ANGPTL4 are associated with reduced risk of coronary artery disease in humans, suggesting that ANGPTL4 and related LPL modulators may be targets for modification of dyslipidemia-related atherosclerotic cardiovascular disease 8 , 9 . (nature.com)
  • With its rapidly increasing disease burden and mortality rate, coronary artery disease (CAD) - the most widely seen cardiovascular disease (CVD), is the growing scourge in India. (deccanchronicle.com)
  • Cardiovascular disease is the leading cause of mortality in the country (25% of all lives lost). (deccanchronicle.com)
  • Several guidelines on the treatment of cardiovascular risk factors base their recommendations on the assertion that diabetes mellitus (DM) is a coronary heart disease (CHD) or cardiovascular disease (CVD) risk equivalent. (revespcardiol.org)
  • Analyses of the national health and nutrition examination follow-up study (NHEFS) found that dietary sodium intake was either inversely 13 14 or directly 15 associated with increased risk of cardiovascular disease. (bmj.com)
  • 19 In one lifestyle intervention trial reporting cardiovascular outcomes, there was a non-significant trend towards reduced cardiovascular disease in those assigned to a reduced sodium intervention. (bmj.com)
  • Small blood vessels called coronary arteries supply oxygen carrying blood to the heart muscle. (medlineplus.gov)
  • In coronary heart disease, the coronary arteries narrow due to the buildup of atheroma or fatty deposits on the vessel walls. (wikipedia.org)
  • We perform detailed anatomic, functional, and physiologic imaging of the coronary arteries, myocardium, cardiac chambers, valves, aorta, pulmonary arteries, and pericardium using cardiac magnetic resonance imaging (MRI) and computed tomography (CT) in adults and pediatric patients suffering from a broad range of congenital and acquired cardiac diseases. (ohsu.edu)
  • The administration of sublingual nitroglycerin dilates the coronary arteries and increases side branch visualization. (medscape.com)
  • Amongst CVD, coronary artery disease (CAD), is denoted as a pathologic process that affects coronary arteries ( 7 ). (amegroups.org)
  • With aggressive cardiac risk factor modification and, at a minimum, annual follow-up with routine non-invasive cardiac evaluation, the majority of aircrew with coronary artery disease can safely return to flight duties. (bmj.com)
  • The consequences of coronary angiographic findings are different in aircrew compared with the general population, and consideration for continuing flight duties of aircrew with known CAD requires a detailed aeromedical review by a cardiac specialist with aviation medicine experience. (bmj.com)
  • Myocardial scarring is the accumulation of fibrous tissue resulting after some form of trauma to the cardiac tissue. (wikipedia.org)
  • Cardiac markers Acute coronary syndromes result from acute obstruction of a coronary artery. (msdmanuals.com)
  • We investigated the incremental prognostic value of coronary and systemic atherosclerosis after acute MI by estimating extra-cardiac artery disease (ECAD) and extent of coronary atherosclerosis. (diva-portal.org)
  • To investigate the effect and mechanism of simvastatin on myocardial injury in cardiac valve surgery with CPB. (hindawi.com)
  • RESULTS: During follow-up, 271 patients had at least one cardiac event, including 64 cardiac deaths and 33 nonfatal myocardial infarctions. (uzh.ch)
  • Trimetazidine (TMZ) is effective at improving clinical outcomes in chronic heart failure and stable coronary artery disease patients. (hindawi.com)
  • Observational analyses suggested inverse associations between incident coronary heart disease, stroke, and all-cause mortality outcomes with 25(OH)D concentration at low 25(OH)D concentrations. (nih.gov)
  • Background: Whether disclosure of a genetic risk score (GRS) for a common disease influences relevant clinical outcomes is unknown. (elsevierpure.com)
  • Long-term clinical outcomes in patients with acute coronary syndromes (ACS) are dependent on various factors such as the demographic profile of the patient, the extent of myocyte necrosis, and the development of arrhythmic and hemodynamic complications [ 1 ]. (pulsus.com)
  • Most studies of heart health consist primarily of male participants, and numerous clinical outcomes such as patient symptoms and treatments do not therefore necessarily apply to women with certain types of heart disease," explained lead investigator Tara L. Sedlak, MD, Vancouver General Hospital Department of Cardiology, University of British Columbia Faculty of Medicine, and British Columbia Women's Hospital, Vancouver, BC, Canada. (eurekalert.org)
  • Inadequately controlled chronic diseases may present a threat to life and well-being during the emergency response to natural disasters. (cdc.gov)
  • An estimate of the possible numbers of people who may require treatment for chronic diseases should help in planning a response, but such information for local areas is not easily accessible. (cdc.gov)
  • We explored how a current surveillance system could be used to provide estimates of the potential needs for emergency treatment of chronic diseases in the wake of a natural disaster. (cdc.gov)
  • this information can assist the medical and public health community in assessing the needs of people with chronic diseases after disasters and in planning relief efforts. (cdc.gov)
  • However, with the devastation of the regional infrastructure, including the medical sector, and the subsequent large-scale displacement of residents from the affected areas, treatment of chronic diseases emerged as a critical concern. (cdc.gov)
  • Inadequately controlled chronic diseases may present a threat to life and well-being in the immediate wake of natural disasters, but their treatment traditionally has not been recognized as a public health or medical priority. (cdc.gov)
  • In wealthier countries with aging populations, the need to address treatment of chronic diseases after a natural disaster requires reevaluation, especially in situations where the medical infrastructure is severely disrupted. (cdc.gov)
  • An estimate of the possible numbers of residents who may require treatment for chronic diseases should help to inform the emergency response to natural disasters. (cdc.gov)
  • Furthermore, information about types of treatment received by patients with chronic diseases and medical equipment used by them may allow emergency response planners to stock and ship appropriate quantities of medical supplies. (cdc.gov)
  • Ischemic mitral regurgitation (IMR) is a frequent complication of left ventricular (LV) global or regional pathological remodeling due to chronic coronary artery disease. (amrita.edu)
  • IMR is defined as mitral regurgitation caused by chronic changes of LV structure and function due to ischemic heart disease and it worsens the prognosis. (amrita.edu)
  • Exclusion criteria were (1) a poor acoustic window precluding satisfactory imaging despite contrast administration, (2) severe valvular heart disease, (3) sustained ventricular arrhythmias or hemodynamic instability, (4) active chest pain within the past 24 hours, (5) known allergy to sulfonamides, (6) pregnancy or lactation, (7) severe chronic obstructive pulmonary disease, and (8) previous coronary artery bypass surgery. (thoracickey.com)
  • Of the 422 patients who consented to participate, 22 (5.2%) met exclusion criteria (10 with inadequate baseline echocardiographic image quality, 3 with sulfonamide allergy, and 9 with severe chronic obstructive pulmonary disease). (thoracickey.com)
  • The Total Worker Health(R) paradigm poses an alternative to traditional workplace health promotion by recognizing the contribution of the organizational and psychosocial work environment to chronic conditions such as heart disease and diabetes. (cdc.gov)
  • Broader public health action is emphasized, including integration of preventive measures against major risk factors for chronic diseases within health services and, particularly in primary health care which has proven to be effective. (who.int)
  • 7KH ZRUOG KHDOWK UHSRUW confirmed that major chronic noncommunicable diseases were responsible for nearly half of the total estimated 52 million deaths in 1996, about 67 000 a day. (who.int)
  • The "epidemiological transition", with its double burden of infectious and noncommunicable diseases, is common to many developing countries, where about two-thirds of the deaths due to circulatory diseases (64%), cancers (60%) and chronic obstructive lung diseases (66%) occur. (who.int)
  • BACKGROUND: Despite the availability of several acute coronary syndrome (ACS) prognostic risk scores (RSs), there is no appropriate score for post-discharge risk stratification for patients after ACS. (pulsus.com)
  • Despite the availability of several acute coronary syndrome (ACS) prognostic risk scores, the majority of them have mostly been validated with respect to in-hospital and short-term (30-day) use [ 2 - 8 ]. (pulsus.com)
  • It is recommended that in aircrew with non-obstructive coronary artery disease or obstructive coronary artery disease not deemed haemodynamically significant, nor meeting the criteria for excessive burden (based on plaque morphology and aggregate stenosis), a return to flying duties may be possible, although with restrictions. (bmj.com)
  • Usually the presence of the obstructive coronary artery disease is revealed in 95% of the cases with STEMI and NON-STEMI1. (romanianjournalcardiology.ro)
  • The intriguing MINOCA syndrome was underdiagnosed in the past because clinicians thought that the absence of the obstructive atheromatous plaque or the acute thrombosis represents the exclusion argu-ments of a true ST-segment-elevation myocardial in-farction, leading to a misinformation and assurance of a favorable outcome in these subjects. (romanianjournalcardiology.ro)
  • Rationale: Recent randomized controlled trials did not show cardiovascular benefits of continuous positive airway pressure (CPAP) in adults with coronary artery disease (CAD) and obstructive sleep apnea (OSA) in intention-to-treat analyses. (lu.se)
  • Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient partitioning. (nature.com)
  • 22 ]. The overall prevalence of ischemic ble burden of high risk factors such as obe- heart diseases in men was 2.3% in the rural sity and hypercholesterolemia and mal- and 4.7% in the urban populations and cor- nutrition and hypocholesterolaemia [ 2 ]. (who.int)
  • Through this mechanism, TMZ is thought to correct disturbances in myocardial cellular homeostasis that result from acute ischemic damage and to protect against cardiomyocyte injury [ 14 , 15 ]. (hindawi.com)
  • In the US, about 1.0 million myocardial infarctions occur annually. (msdmanuals.com)
  • Diagnosis and therapy of Kawasaki disease in children. (thieme-connect.com)
  • We obtained hospital discharge data from the Canadian Institute for Health Information (CIHI) administrative database for all patients discharged from an acute care hospital in Ontario with a most responsible diagnosis (that which accounted for most of the patient's stay) of an AMI ( International Classification of Diseases, 9th revision code 410) between Apr. (cmaj.ca)
  • However, in models of recurrent thrombosis myocardial ischaemia also improves arterial patency. (unicatt.it)
  • Thirty-nine patients with coronary artery disease and 12 controls were studied by radionuclide ventriculography. (nih.gov)
  • Of the patients with coronary artery disease, 23 (59 percent) had wall-motion abnormalities during periods of mental stress and 14 (36 percent) had a fall in ejection fraction of more than 5 percentage points. (nih.gov)
  • Magnetic Resonance Imaging (MRI) is occasionally used for more advanced problem solving and mediastinal diseases or in younger patients with radiation exposure issues. (ohsu.edu)
  • Data regarding the relative diagnostic value of each of these parameters when assessed during the same examination in patients with suspected coronary artery disease (CAD) are lacking. (thoracickey.com)
  • This study investigated whether myocardial ischaemia has any effect on platelet function in patients with coronary artery disease. (unicatt.it)
  • PATIENTS AND DESIGN: Twenty patients with low-workload myocardial ischaemia underwent, in a randomised crossover study, two treadmill exercise stress tests (EST) on two separate days: a single maximal EST (EST-1) and a maximal EST (EST-2) performed 45 minutes after a low-workload EST stopped at 1-mm ST depression (p-EST). (unicatt.it)
  • For all patients, the longitudinal coronary atherosclerotic extent, expressed as Sullivan extent score (SES) was calculated. (diva-portal.org)
  • The risk ratio of stroke in patients with AF and nonrheumatic heart disease has been found in various studies to range from 2.3 during five years of follow-up 9 to 7.0 during 14 years of follow-up. (aafp.org)
  • There are some mechanisms that might be involved in the appearance of the MINOCA syndrome inclu-ding the atheromatous plaque erosion, embolism or epicardial coronary artery dissection. (romanianjournalcardiology.ro)
  • One third of these asymptomatic individuals had coronary microvascular dysfunction, and reduced MBFR was highly prognostic for mortality. (medscape.com)
  • To assess the effectiveness of multiple risk factor intervention in reducing cardiovascular risk factors, total mortality, and mortality from coronary heart disease among adults. (bmj.com)
  • Changes in systolic and diastolic blood pressure, smoking rates, blood cholesterol concentrations, total mortality, and mortality from coronary heart disease. (bmj.com)
  • In the nine trials with clinical event end points the pooled odds ratios for total and coronary heart disease mortality were 0.97 (95% confidence interval 0.92 to 1.02) and 0.96 (0.88 to 1.04) respectively. (bmj.com)
  • Primary prevention programmes in many countries attempt to reduce mortality and morbidity due to coronary heart disease through modifying risk factors. (bmj.com)
  • We aimed to characterise dose-response relationships between 25-hydroxyvitamin D (25[OH]D) concentrations and risk of coronary heart disease, stroke, and all-cause mortality in observational and Mendelian randomisation frameworks. (nih.gov)
  • In population-wide genetic analyses, there were no associations of genetically-predicted 25(OH)D with coronary heart disease, stroke, or all-cause mortality. (nih.gov)
  • Even if the clinical parti-cularities of the MINOCA subjects differs comparing with the AMI group, the mortality rate at 1 month and 1 year are similar proving that the myocardial infarcti-on with nonobstructive coronary artery disease is not a benign condition and further tests should reveal the underlying etiology1. (romanianjournalcardiology.ro)
  • In short, the disease segments with high scanned volumes and/or high value (e.g., preventing mortality with early detection) have received the most money thus far. (idtechex.com)
  • B: funnel plot comparing coronary heart disease mortality between men in the DM-CHD- group with men in the DM+CHD- group. (revespcardiol.org)
  • 2021 ACC/AHA/SCAI guideline for coronary artery revascularization: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. (medlineplus.gov)
  • We computed a comparability ratio (coronary heart disease deaths recorded on death certificates divided by validated coronary heart disease deaths) to quantify agreement between death certificate determination and clinical judgment. (cdc.gov)
  • 3 4 Given the evidence from quasi-experimental studies, such as the North Karelia project 5 6 and the Stanford heart disease prevention programme, 7 8 9 multiple risk factor intervention using counselling and educational methods is widely believed to be efficacious and cost effective and worthy of expansion. (bmj.com)
  • It is recommended that aircrew with haemodynamically significant coronary artery disease (defined by a decrease in fractional flow reserve) or a total burden of disease that exceeds an aggregated stenosis of 120% are grounded. (bmj.com)
  • Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. (nature.com)
  • efficacy in reducing the incidence of disease seems to be associated with the degree of control achieved. (bmj.com)
  • The incidence of AF increases with age and with the presence of structural heart disease. (aafp.org)
  • Coronary heart disease (CHD) is the leading cause of death for adults in the United States, and stroke ranks third (1). (cdc.gov)
  • Observational analyses were undertaken using data from 33 prospective studies comprising 500 962 individuals with no known history of coronary heart disease or stroke at baseline. (nih.gov)
  • Mendelian randomisation analyses were performed in four population-based cohort studies (UK Biobank, EPIC-CVD, and two Copenhagen population-based studies) comprising 386 406 middle-aged individuals of European ancestries, including 33 546 people who developed coronary heart disease, 18 166 people who had a stroke, and 27 885 people who died. (nih.gov)
  • In Scottish, 16 Finnish, 17 and Japanese 18 studies, a single measure of urinary excretion was directly correlated with increased risk of coronary heart disease or stroke, although this direct relation has been disputed by some. (bmj.com)
  • This assessment must incorporate angiographic findings, a detailed risk assessment and a nuanced management plan that must include aggressive control of the atherosclerotic disease process to ensure safety of flight. (bmj.com)
  • A sedentary lifestyle and poor cardiorespiratory fitness are independent risk factors for coronary atherosclerotic heart disease [ 8 ]. (hindawi.com)
  • Evaluation of Kawasaki disease risk-scoring systems for intravenous immunoglobulin resistance. (thieme-connect.com)
  • Elevated blood pressure, smoking, diabetes and hyperlipidemia still remain the main risk factors for development of the coronary heart disease, while physical inactivity, obesity, poor nutrition and low socio-economic status are considered to be the predisposing factors. (amegroups.org)
  • We hope our findings highlight the importance of having a dedicated women-specific heart center, which provides comprehensive care for women with heart disease by providing risk factor assessment, referral to psychiatrists, exercise classes, smoking cessation treatment, and consultation with a dietitian in addition to a focus on conditions such as INOCA that are more common in women. (eurekalert.org)
  • 0.001, adjusted for Global Registry of Acute Coronary Events risk score parameters 1.8, 95% CI 1.1-3.0, P = 0.019). (diva-portal.org)
  • Overtime work is strongly implicated in cardiovascular morbidity, with elevated risk of incident coronary heart disease (Virtanen et al. (cdc.gov)
  • I'm Commander Ibad Khan, and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
  • An individual's risk for getting a heart disease can be caused fully or partially due to the genetic factors. (deccanchronicle.com)
  • Increase in tobacco use and a shift to "western" high-energy diets, creating higher risk of noncommunicable disease - often in a polluted environment - are more rapid in developing countries. (who.int)
  • Numerous studies over the last 40 years, have revealed certain risk factors for noncommunicable diseases and thus the health benefit of programmes to reduce such risks. (who.int)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • US data for 2003 through 2006 from Centers for Disease Control and Prevention. (cdc.gov)
  • The survey was conducted by the Ambulatory Care Statistics Branch of the National Center for Health Statistics, Centers for Disease Control and Prevention. (cdc.gov)
  • Coronary artery disease (CAD) is the leading cause of death globally, currently accounting for 17 million deaths per year, and projected to increase to more than 23 million by 2030. (bmj.com)
  • We conducted a cross-sectional validation study by using a random sample of death certificates that recorded in-hospital deaths in New York City from January through June 2003, stratified by neighborhoods with low, medium, and high coronary heart disease death rates. (cdc.gov)
  • Coronary heart disease appears to be substantially overreported as a cause of death in New York City among in-hospital deaths. (cdc.gov)
  • Age-adjusted deaths from coronary heart disease in New York City (NYC) versus the United States overall. (cdc.gov)
  • Cardiovascular diseases (CVD) are among leading causes of death worldwide and amongst CVD, coronary artery disease (CAD) accounts for almost half of all cardiovascular deaths as the most common cause of death in the developed world. (amegroups.org)
  • According to the World Health Organization (WHO), cardiovascular diseases (CVD) are among leading causes of death worldwide and account for 31% of all global deaths and 47% of all deaths at the European level ( 1 ). (amegroups.org)
  • But treatments help manage the symptoms, reduce the number of relapses, and delay the disease progressing (worsening). (healthline.com)