Cell LineCell Line, TumorPoint MutationMutation, MissenseMutationCell Line, TransformedMolecular Sequence DataBase SequenceFrameshift MutationRNA, MessengerAmino Acid SequenceTumor Markers, BiologicalTumor Cells, CulturedTransfectionGerm-Line MutationTumor Necrosis Factor-alphaTumor BurdenPolymerase Chain ReactionTumor Suppressor Protein p53Cell DivisionSignal TransductionGenes, Tumor SuppressorCell ProliferationPedigreeCells, CulturedBlotting, WesternReverse Transcriptase Polymerase Chain ReactionMembrane ProteinsExonsNeoplasm ProteinsGene Expression Regulation, NeoplasticPhenotypeTumor Suppressor ProteinsKineticsNeoplasms, ExperimentalDNA PrimersGene ExpressionDNA, NeoplasmDNA-Binding ProteinsApoptosisTranscription, GeneticCloning, MolecularWilms TumorCell SurvivalDNA Mutational AnalysisPromoter Regions, GeneticDNACell Transformation, NeoplasticProtein BindingAdenocarcinomaAntibodies, MonoclonalRecombinant ProteinsHeterozygoteTranscription FactorsMutation RateMice, NudeTime FactorsCarrier ProteinsTransplantation, HeterologousFluorescent Antibody TechniqueAmino Acid SubstitutionCricetinaeBrain NeoplasmsAntineoplastic AgentsBinding SitesImmunohistochemistryColonic NeoplasmsPhosphorylationMutagenesis, Site-DirectedAllelesMice, Inbred BALB CBreast NeoplasmsPolymorphism, Single-Stranded ConformationalGene Expression RegulationOvarian NeoplasmsCarcinoid TumorProto-Oncogene ProteinsFibroblastsNeoplasm MetastasisNeoplasmsXenograft Model Antitumor AssaysGenes, p53MutagenesisCell DifferentiationSequence Analysis, DNARecombinant Fusion ProteinsMice, Inbred C57BLProtein Structure, TertiaryAntigens, NeoplasmMammary Neoplasms, ExperimentalMicroscopy, ElectronDose-Response Relationship, DrugLiver NeoplasmsPlasmidsProteinsNeuroendocrine TumorsCell MembraneHeLa CellsHomozygoteChromosome Mapping