Mutation tumor suppressor protein p53. Medical search. Frequent questions

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Anatomy15

Cell Line, Tumor Cell Line Tumor Cells, Cultured HeLa Cells Fibroblasts Cells, Cultured Cell Nucleus COS Cells HCT116 Cells Cell Line, Transformed Cytoplasm NIH 3T3 Cells HEK293 Cells 3T3 Cells Epithelial Cells

Organisms11

Spodoptera Mice, Knockout Papillomaviridae Mice, Nude Mice, Inbred C57BL Mice, Transgenic Mice, Inbred BALB C Escherichia coli Cercopithecus aethiops Drosophila Saccharomyces cerevisiae

Diseases26

Neoplasms Cell Transformation, Neoplastic Kidney Neoplasms Breast Neoplasms Wilms Tumor Osteosarcoma Adenocarcinoma Neurofibromatosis 2 Carcinoma, Renal Cell Neoplasms, Experimental von Hippel-Lindau Disease Liver Neoplasms Lung Neoplasms Skin Neoplasms Brain Neoplasms Retinoblastoma Colonic Neoplasms Carcinoma, Squamous Cell Carcinoma, Hepatocellular Disease Progression Neoplasm Metastasis Ovarian Neoplasms Glioblastoma Carcinoid Tumor Disease Models, Animal Chromosome Deletion

Chemicals and Drugs90

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Proto-Oncogene Proteins c-mdm2 Von Hippel-Lindau Tumor Suppressor Protein Cyclin-Dependent Kinase Inhibitor p21 Tumor Suppressor Protein p14ARF Nuclear Proteins Cyclins DNA-Binding Proteins Retinoblastoma Protein Proto-Oncogene Proteins Transcription Factors Cell Cycle Proteins Ubiquitin-Protein Ligases Oncogene Proteins, Viral Adenovirus E1B Proteins RNA, Messenger DNA Ubiquitins Neurofibromin 2 DNA Primers Recombinant Fusion Proteins Adenomatous Polyposis Coli Protein Antigens, Polyomavirus Transforming bcl-2-Associated X Protein Cyclin-Dependent Kinase Inhibitor p16 Proteasome Endopeptidase Complex Trans-Activators Recombinant Proteins PTEN Phosphohydrolase Neoplasm Proteins Proteins Repressor Proteins Protein-Serine-Threonine Kinases Proto-Oncogene Proteins c-bcl-2 Ligases E2F Transcription Factors Serine Carrier Proteins RNA, Small Interfering Tumor Markers, Biological Retinoblastoma-Like Protein p107 E2F1 Transcription Factor Membrane Proteins Retinoblastoma-Like Protein p130 Transcription Factor DP1 Suppressor of Cytokine Signaling Proteins DNA, Neoplasm Papillomavirus E7 Proteins Retinoblastoma-Binding Protein 1 WT1 Proteins Phosphoproteins Tumor Necrosis Factor-alpha Cyclin-Dependent Kinases Intracellular Signaling Peptides and Proteins Ubiquitin Hypoxia-Inducible Factor 1, alpha Subunit Phosphoric Monoester Hydrolases Cytoskeletal Proteins Adaptor Proteins, Signal Transducing Drosophila Proteins Apoptosis Regulatory Proteins DNA, Complementary BRCA1 Protein Adenovirus E1A Proteins beta Catenin Neurofibromin 1 Luciferases Protein Isoforms Antineoplastic Agents Cyclin-Dependent Kinase Inhibitor p27 Cyclin-Dependent Kinase 4 Proto-Oncogene Proteins c-myc Viral Proteins Oncogene Proteins RNA, Neoplasm Suppressor Factors, Immunologic Adenovirus E4 Proteins MicroRNAs Hypoxia-Inducible Factor 1 Multiprotein Complexes Protein Kinases Cysteine Endopeptidases Cyclin D1 Multienzyme Complexes Cyclin-Dependent Kinase 2 Glutathione Transferase Proto-Oncogene Proteins c-akt Enzyme Inhibitors Homeodomain Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment31

Transfection Blotting, Western Precipitin Tests Models, Biological Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Immunohistochemistry DNA Mutational Analysis Tumor Burden Mutagenesis, Site-Directed Cloning, Molecular Immunoblotting Chromosome Mapping Immunoprecipitation Pedigree Amino Acid Substitution Neoplasms, Experimental Transplantation, Heterologous Two-Hybrid System Techniques Models, Molecular Sequence Alignment Gene Expression Profiling Microscopy, Fluorescence Sequence Analysis, DNA Flow Cytometry Fluorescent Antibody Technique Chromatin Immunoprecipitation Oligonucleotide Array Sequence Analysis Neoplasm Transplantation Disease Models, Animal Models, Genetic

Phenomena and Processes82

Genes, Tumor Suppressor Mutation Protein Binding Genes, p53 Apoptosis Transfection Base Sequence Point Mutation Amino Acid Sequence Transcriptional Activation DNA Damage Cell Cycle Promoter Regions, Genetic Mutation, Missense Transcription, Genetic Binding Sites Phosphorylation Gene Expression Regulation, Neoplastic Protein Structure, Tertiary Signal Transduction Cell Proliferation Down-Regulation Cell Division Ultraviolet Rays Gene Expression Regulation Genes, Suppressor Consensus Sequence Acetylation Cell Survival Suppression, Genetic Frameshift Mutation Gene Deletion Germ-Line Mutation Gene Silencing Loss of Heterozygosity Protein Conformation RNA Interference DNA Methylation Exons Phenotype Alleles Sequence Homology, Amino Acid Sequence Deletion G1 Phase Mutagenesis Cell Aging Plasmids Gene Expression Heterozygote Genes, Retinoblastoma Genes, Neurofibromatosis 2 Polymorphism, Single-Stranded Conformational Oncogenes Amino Acid Substitution Genes, Reporter Time Factors Genes, APC Ubiquitination Up-Regulation Amino Acid Motifs Genotype Genes, p16 Cell Differentiation Cell Movement DNA Repair Homozygote Protein Stability S Phase Protein Transport Enzyme Activation Genes, Dominant Mutation Rate Genes, ras Protein Processing, Post-Translational Gamma Rays Genetic Vectors Genes, Wilms Tumor Active Transport, Cell Nucleus Microsatellite Repeats Chromosome Deletion Alternative Splicing CpG Islands

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Genes, Tumor Suppressor Proto-Oncogene Proteins c-mdm2 Mutation Von Hippel-Lindau Tumor Suppressor Protein Cyclin-Dependent Kinase Inhibitor p21 Cell Line, Tumor Protein Binding Genes, p53 Apoptosis Tumor Suppressor Protein p14ARF Nuclear Proteins Molecular Sequence Data Cell Line Cyclins DNA-Binding Proteins Transfection Retinoblastoma Protein Base Sequence Tumor Cells, Cultured Point Mutation Proto-Oncogene Proteins Amino Acid Sequence Transcriptional Activation DNA Damage Cell Cycle Transcription Factors Promoter Regions, Genetic Mutation, Missense Transcription, Genetic Binding Sites Cell Cycle Proteins Phosphorylation Gene Expression Regulation, Neoplastic Ubiquitin-Protein Ligases Protein Structure, Tertiary Signal Transduction Oncogene Proteins, Viral Cell Proliferation Blotting, Western Adenovirus E1B Proteins RNA, Messenger DNA Down-Regulation Cell Division HeLa Cells Fibroblasts Ultraviolet Rays Gene Expression Regulation Ubiquitins Neoplasms Neurofibromin 2 DNA Primers Cells, Cultured Recombinant Fusion Proteins Adenomatous Polyposis Coli Protein Antigens, Polyomavirus Transforming bcl-2-Associated X Protein Genes, Suppressor Precipitin Tests Consensus Sequence Cyclin-Dependent Kinase Inhibitor p16 Proteasome Endopeptidase Complex Cell Nucleus Trans-Activators Recombinant Proteins PTEN Phosphohydrolase Spodoptera Cell Transformation, Neoplastic Neoplasm Proteins Proteins Repressor Proteins Mice, Knockout Protein-Serine-Threonine Kinases Models, Biological Proto-Oncogene Proteins c-bcl-2 Acetylation Ligases Cell Survival Papillomaviridae E2F Transcription Factors Suppression, Genetic Serine Carrier Proteins RNA, Small Interfering Frameshift Mutation Gene Deletion Polymerase Chain Reaction Tumor Markers, Biological Germ-Line Mutation Retinoblastoma-Like Protein p107 Gene Silencing Reverse Transcriptase Polymerase Chain Reaction Loss of Heterozygosity E2F1 Transcription Factor Membrane Proteins Protein Conformation Retinoblastoma-Like Protein p130 RNA Interference

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