• Neo-Darwinism combines Darwin's theory of evolution by natural selection with August Weismann's theory of the immortal, inviolable germline, which, through Mendelian and molecular genetics became the Central Dogma. (i-sis.org.uk)
  • After positions at the Max Planck Institute for Molecular Cell Biology and Genetics in Dresden, Germany, University College London and the Francis Crick Institute in the UK, Andy Oates recently joined École Polytechnique Fédéral de Lausanne (EPFL) in Switzerland where he is the head of the Timing, Oscillation, Patterns Laboratory. (ens-lyon.fr)
  • Anti-infective agents are secondary metabolites produced and obtained from a different sources (plants, bacteria, virus, fungi, and marine oceans) with antibacterial or antiviral properties. (benthamscience.com)
  • These tissues are also naturally colonized by a complex community of bacteria, viruses, fungi and parasites, and this is known as the microbiome. (charite.de)
  • They include mitogens, lipopolysaccharides , and the synthetic polymers Poly A-U and Poly I-C . Viruses, bacteria, and protozoa have been also known to induce interferons . (lookformedical.com)
  • Viruses and bacteria share many, many molecular structures. (techbriefly.com)
  • We also perform experiments using bacteria and bacteriophage (viruses that infect bacteria) in our lab. (ku.dk)
  • Any life forms are infected by viruses, and bacteria are no exception. (ku.dk)
  • This is the so-called Central Dogma of molecular biology. (i-sis.org.uk)
  • I am very interested to study the effects of these pollutants on the ecology and function of soil microbial communities using biochemical (PLFA) and molecular biology techniques. (moa.gov.cy)
  • Dr. Jevrosima Stevanovic's research interest includes: honey bee biology and pathology, animal genetic resources, molecular genetic analyses in veterinary medicine. (scitechnol.com)
  • Molecular biology and biotechnological application of Achaea. (bits-pilani.ac.in)
  • Molecular biology of parasite and vector (with special emphasis to Plasmodium-Anopheles, Dengue-Aedes);Cellular and humoral mechanisms involved inimmunityto parasites;Immunomodulation in vectors;Vector parasite interactions and control strategies - Disease symptoms, Molecular approaches to diagnosis, Epidemiology, drug targets, vaccine strategies and proteomic approaches, prophylaxis, treatments to parasitic diseases and vector control measures, mechanisms of drug resistance in parasites or vectors. (bits-pilani.ac.in)
  • If you are interested in projects related to biological problems, the course 'Dynamical Models in Molecular Biology' is also strongly recommended. (ku.dk)
  • Even with better understanding of molecular oncology and identification of genomic drivers of these processes, there has been a relative lag in identifying and appreciating the cellular drivers of both invasion and resistance. (frontiersin.org)
  • On a molecular level, this progresses via various chemical and physiological processes. (artandobject.com)
  • It can readily be embedded in extended models of the complete HIV-1 reverse transcription process, or analogous processes in other viruses and help to guide drug development and improve our understanding of the mechanisms of resistance development during treatment. (plos.org)
  • We study phenomena in various scales, from intracellular processes, collective behaviours of cells and agents, to species competition in an ecological scale, with tools from dynamical systems, stochastic processes, and individual-based models. (ku.dk)
  • Innate immunity occurs rapidly and can act in just a few hours, well before the other two forms of immunity - humoral immunity (the production of neutralizing antibodies that block virus entry into cells) and cell-mediated immunity (involving white blood cells such as cytotoxic lymphocytes that are capable of destroying infected cells). (pasteur.fr)
  • Scientists from the Virus and Immunity Unit (Institut Pasteur/CNRS) investigated viral fusion, the mechanism by which viral membranes and cellular membranes fuse, allowing viral genetic material to enter the target cell. (pasteur.fr)
  • Our findings give us a better understanding of the harmful effects of SARS-CoV-2 on cells and the role of innate immunity and interferon in controlling infection, " comments Olivier Schwartz, lead author of the study and Head of the Virus and Immunity Unit at the Institut Pasteur. (pasteur.fr)
  • In line with the limited cargo specificity of connexins, the proteins that assemble gap junction channels, most connexins tested were able to confer this bystander immunity, thus indicating a broad physiological relevance of this local immune collaboration. (roma2024.com)
  • Unlike the phenomenon of trained immunity, the postacute SARS-CoV-2 epigenetic landscape we identify is antiprotective. (simonsfoundation.org)
  • In the study, the researchers showed that, in the laboratory , these people not exposed to COVID-19 showed what is known as cross immunity reaction against molecules present in the virus. (techbriefly.com)
  • Development and exploitation of advanced molecular and biochemical methods for gene identification and characterization of genetic traits and their mode of action. (moa.gov.cy)
  • We have reported that many insults can trigger cells to activate a cellular death pathway (Nature, 361:739-742, 1993), that several viruses encode proteins to block attempted cell suicide (Proc. (hopkinsmedicine.org)
  • At the same time, a few reports have documented the phenomenon of cytokine-independent activation of bystander cells via gap junctions in the context of bacterial infection12, irradiation13 or DNA transfection14. (roma2024.com)
  • We are interested if there are universal, quantitative rules that most, if not all, bacterial viruses follow. (ku.dk)
  • For example, is the virus production rate simply proportional to the bacterial hosts' growth rate? (ku.dk)
  • Or can we categorize different classes of viruses according to how they manipulate the bacterial physiological state, with each class having their quantitative relations between bacterial growth and viral growth? (ku.dk)
  • The ultimate goal of bioethics is providing access to therapeutic cells for the treatment of complex cellular and molecular phenomena. (takepharmacologyexam.com)
  • It is useful in studies including physiology of humans, animals, plants and microorganisms, differential diagnosis of diseases and identification of pathogens, biotaxonomy of organisms, stress and pathogenesis physiology, physiological basis for disease resistance, developmental physiology and screening for commercially important enzymes and many other applications. (wikipedia.org)
  • 94: 690-694, 1997), that cellular anti-death genes can alter the pathogenesis of virus infections (Nature Med. (hopkinsmedicine.org)
  • But interferon counters this phenomenon by inducing cellular proteins that prevent the fusion of infected cells. (pasteur.fr)
  • Interferon secreted by leukocytes , fibroblasts , or lymphoblasts in response to viruses or interferon inducers other than mitogens, antigens , or allo-antigens. (lookformedical.com)
  • The study will examine the structure and behavior of lightning elves, and other atmospheric electrical-discharge phenomena, and is a follow-up experiment to fallen first Israeli Ilan Ramon's Meidex experiment on his STS-107 mission aboard the Columbia shuttle. (calcalistech.com)
  • Anti-infective agents (antibacterial or antiviral) possess either a bactericidal/virucidal or bacteriostatic /virustatic ability against microbes and viruses. (benthamscience.com)
  • All three virus studies support an antiviral activity for Aβ that involves viral agglutination. (alzforum.org)
  • On recognition of virus-derived nucleic acids, innate immune signalling initiates cell-autonomous antiviral effector mechanisms that aim to block viral propagation. (roma2024.com)
  • social and biological phenomena. (who.int)
  • During the 2000-2001 Gulu Ebola virus disease outbreak, an international response team, including representatives from the US Centers for Disease Control and Prevention, or CDC, provided clinical and technical assistance. (cdc.gov)
  • We have shown that anti-apoptotic Bcl-2 family proteins can be converted into killer molecules (Science 278:1966-8, 1997), that Bcl-2 family proteins interact with regulators of caspases and regulators of cell cycle check point activation (Molecular Cell 6:31-40, 2000). (hopkinsmedicine.org)
  • cDCs, which do not receive this IFN-I signaling during the basal state, cannot fulfill the physiological functions which they perform as part of the body's fight against pathogens," explains the microbiologist. (charite.de)
  • This phenomenon occurs well before the production of neutralizing antibodies. (pasteur.fr)
  • When one of these molecules that has remained unchanged for so long occurs in two different viruses, the body is able to detect both even if it has only faced one of them. (techbriefly.com)
  • Upper-atmospheric lightning, occasionally referred to as "lightning elves" is a form of electrical-breakdown phenomena that occurs well above the altitudes of normal lightning and storm clouds. (calcalistech.com)
  • This system drives the rhythmic, sequential, and precise formation of embryonic body segments, exhibiting rich spatial and temporal phenomena spanning from molecular to tissue scales. (ens-lyon.fr)
  • Of particular interest to our group are the mechanisms by which Bcl-2 family proteins and other factors regulate programmed cell death, particularly in the nervous system, in cancer and in virus infections. (hopkinsmedicine.org)
  • In addition, Bcl-2 family proteins have normal physiological roles in regulating mitochondrial fission/fusion and mitochondrial energetics to facilitate neuronal activity in healthy brains. (hopkinsmedicine.org)
  • Overall, these are very important physiological roles of AA relating this molecule exclusively to antioxidant functions. (deepdyve.com)
  • However, the molecular mechanisms responsible for these effects remained elusive. (roma2024.com)
  • Physiological phenomena whether at the cellular or molecular level in living organisms are driven either directly or indirectly by enzyme reactions. (wikipedia.org)
  • This mechanism may underlie ascorbate release, signalling phenomena, apoplastic redox reactions, iron acquisition, and control the ionic and electrical equilibrium (together with K+ efflux via GORK channels). (deepdyve.com)
  • Nobel Prize-winning physicist Steven Chu is the William R. Kenan, Jr., Professor of Physics, Professor of Molecular & Cellular Physiology in the Medical School and Professor of Environmental Science and Engineering in the Doerr School of Sustainability at Stanford University. (stanford.edu)
  • Perhaps surprisingly, the manner of its secretion strongly resembles, on the molecular level, one of the most intensively studied physiological phenomena: neurotransmitter release. (stanford.edu)
  • It may not be a valid manifestation on a physiological level. (techbriefly.com)
  • In fact, the way you breathe strongly affects the chemical and physiological activities in your body. (artandobject.com)
  • They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. (lookformedical.com)
  • The development of resistance is obviously a natural phenomenon. (bats.ch)
  • A closely related virus that circulates in Australia (Kunjin [KUN]) has never been associated with outbreaks of human or animal diseases, including bird diseases, nor have bird deaths been reported from enzootic transmission foci in Africa, where a virus that shares 96.5% nucleotide identity with the NY99 strain has previously been isolated ( 16 , 17 ). (cdc.gov)
  • Feedforward inhibition driven by the mediodorsal nucleus of the thalamus (MD) has been previously observed, but its physiological function and regulation remain unknown. (researchsquare.com)
  • The inhibition of TNF-alpha release (and many other shedding phenomena) by hydroxamic acid-based inhibitors indicates that one or more metalloproteinases is involved. (embl.de)
  • Some respiratory viral infections can aggravate allergic rhinitis, such as a respiratory syncytial virus (RSV) and human metapneumovirus (hMPV). (hindawi.com)
  • The Ebolavirus genus includes 5 different viruses that result in different case-fatality rates: Ebola virus, Sudan virus, and Bundibugyo virus cause fatal infections, but neither Tai Forest virus nor Reston virus has been associated with human fatalities. (cdc.gov)
  • For example, nosocomial Ebola virus disease infections mostly occur in adults working on hospital wards, and children are not usually caregivers for Ebola virus disease patients. (cdc.gov)
  • human polyomavirus 1) infections are asymptomatic in most individuals, and the virus persists throughout life without harm. (simonsfoundation.org)
  • Laboratory experiences integrated with lecture enable students to examine anatomical and physiological phenomena of the human body. (wvstateu.edu)
  • Bourgade K, Garneau H, Giroux G, Le Page AY, Bocti C, Dupuis G, Frost EH, Fülöp T Jr . β-Amyloid peptides display protective activity against the human Alzheimer's disease-associated herpes simplex virus-1 . (alzforum.org)
  • These original observations, obtained in in vitro models with IFITM overexpression, now need to be reproduced in physiological models of human bronchial cells. (pasteur.fr)
  • To celebrate 100 years of this seminal discovery, one of the first to show that a virus could cause a human disease, an international symposium was held on the 20 November 2009, in Vienna, Austria ( http://www.meduniwien.ac.at/100yearspolio ). (springer.com)
  • Imagine the human stress response similar to a virus causing disease and Tanturi Campos , the vaccine against the virus. (tangofolly.com)
  • It plays on the idea that exposure to other viruses (various human coronaviruses, for example) could trigger an immune response that helps control COVID-19. (techbriefly.com)
  • Although these researchers have verified this phenomenon in a petri dish, it is necessary to ensure that this also happens in the human body. (techbriefly.com)
  • Crow deaths were observed after West Nile virus (WNV) was introduced into North America, and this phenomenon has subsequently been used to monitor the spread of the virus. (cdc.gov)
  • Corvids, including the American Crow ( Corvus brachyrhynchos ), appear to be most susceptible ( 5 , 6 ), and corvid deaths have subsequently been used as a sentinel to track the spread of the virus ( 7 ). (cdc.gov)
  • In 1909, Landsteiner and Popper reported the identification of a virus, subsequently called poliovirus (PV), as the causative agent of poliomyelitis [ 20 ]. (springer.com)
  • Fever may also be related to necrotic-inflammatory phenomena of the tumor and/or to alterations in liver function and consequent disorders of steroidogenesis. (medscape.com)
  • Outbreaks of Ebola virus disease occur sporadically in sub-Saharan Africa and are associated with exceptionally high case-fatality rates. (cdc.gov)
  • Pediatric patients have been underrepresented in Ebola virus disease studies because total numbers of affected children in any given Ebola virus disease outbreak, whether associated with Ebola virus or Sudan virus or Bundibugyo virus are usually low because of outbreak dynamics and societal structure. (cdc.gov)
  • The relatively large number of pediatric cases in this outbreak enabled closer investigation of factors associated with increased survival of pediatric patients with Ebola virus disease. (cdc.gov)
  • Samples collected during the Gulu outbreak have been invaluable for advancing understanding of Ebola virus disease pathophysiology. (cdc.gov)
  • In addition to the samples from the 55 pediatric patients, people less than 21 years of age, who had laboratory-confirmed Ebola virus disease, we selected samples from 50 adult patients, more than 21 years of age, who had laboratory-confirmed infection. (cdc.gov)
  • Specific molecular sites or structures on or in cells with which interferons react or to which they bind in order to modify the function of the cells. (lookformedical.com)
  • One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. (lookformedical.com)
  • Hard-driving molecular virologist who used 'advanced chemistry to unlock the tightly held secrets of viruses' was also a hearty mountain man, scaling peaks in Alaska and Nepal. (stanford.edu)
  • The disease onset is nonspecific and is characterized by abrupt onset of fever, fatigue, headache, myalgia, and gastrointestinal distress 3 to 13 days after exposure to the virus. (cdc.gov)
  • While differential gene expression largely returned to baseline levels after the virus became undetectable, some differentially methylated sites persisted for months of follow-up, with a pattern resembling autoimmune or inflammatory disease. (simonsfoundation.org)
  • To characterize the molecular mechanism of the cGASCSTING pathway better, we used HEK cells stably transduced with an amino-terminally mCherry-tagged STING construct (HEK STING)17. (roma2024.com)
  • We examined the moderating mechanism of HPA-axis function, and discussed the effect of physiological toughness from the respective of resources and demands. (las.ac.cn)
  • He asserts that we are repeated simulations of the same phenomenon, adhering to mathematical formulae like Phi or the Golden Ratio. (artandobject.com)
  • Prof. Pascal H. Fries Molecular Recognition of Lanthanide(III) Ion Complexes. (unige.ch)
  • Using real-time video microscopy, the scientists demonstrated that infected cells fuse with neighboring cells to form syncytia, or giant cells containing dozens of virus-producing cells, which eventually die. (pasteur.fr)
  • Moreover, virus-infected cells alert non-infected neighbouring cells, a process largely attributed to the expression and secretion of cytokines and chemokines. (roma2024.com)
  • Under these circumstances, the virus can replicate robustly in proximal tubule epithelial cells (PT). (simonsfoundation.org)
  • Molecular docking reveals that the hydroxyl group of the HDAC inhibitor is crucial for targeting. (bvsalud.org)
  • locations that released primarily rely in each Keyboard Organized the phenomenon to Darwin's fund, and could develop created him onto the infected sight as evolutionary as 1866, the excerpt Mendel's most new catalog presented based. (bannig.de)
  • We postulated that this phenomenon was primarily due to the increased failure rate of evoking action potentials in parvalbumin-expressing inhibitory neurons. (researchsquare.com)
  • Viral fusion can also occur when the cell is infected and produces new viruses. (pasteur.fr)
  • Molecular Cell. (lu.se)
  • The information from both stations will be compared and analyzed, and grant researchers unique insights, helping them find possible explanations for electrical phenomena in the atmosphere. (calcalistech.com)
  • In this review, we summarized the interactions of noncoding RNAs and viruses in the occurrence and development of AR, along with the treatments focusing on the noncoding RNAs in the past five years. (hindawi.com)
  • This phenomenon reflects the ability of species to grow under favorable conditions while minimizing losses during unfavorable conditions owing to long-lived life stages [ 25 , 26 ]. (nature.com)