In mice with implanted glioblastoma, translocator protein (TSPO) radiotracer uptake per tumor cell was higher compared to tumor-associated microglia/macrophages (TAMs), validated by protein levels. (bvsalud.org)
Astrocytes3
We used immunohistochemical methods to detect evidence of neuroinflammation in the form of reactive microglia and astrocytes. (canlyme.com)
Ligand engagement of Toll-like receptors regulates their expression in cortical microglia and astrocytes. (medscape.com)
We have recently demonstrated that B. abortus infects microglia and astrocytes, eliciting the production of a variety of pro-inflammatory cytokines which contribute to CNS damage. (biomedcentral.com)
Vitro2
We further analyzed whether atypical forms similar to those induced in vitro may also occur in vivo , in brains of three patients with Lyme neuroborreliosis. (canlyme.com)
Antagonist of the neurokinin-1 receptor curbs neuroinflammation in ex vivo and in vitro models of Lyme neuroborreliosis. (medscape.com)
CBC News: June 12, 2022 Study may help reduce the risk of humans contracting Lyme disease When most Maritimers find a tick on themselves or their animals, their first instinct is to pull it off and destroy it. (canlyme.com)
Disease8
July 20, 2015 Lyme disease patients denied treatment based on faulty tests Vancouver, BC ~ Confidential documents, obtained through a Freedom of Information (FOI) request, show doctors and other senior government officials in British Columbia raising serious doubts about accuracy of Lyme disease blood tests. (canlyme.com)
09 2014, 8:00 AM EDT Saying she was frustrated because patients weren't being adequately diagnosed or treated for Lyme disease, Liz Zubek quit British Columbia's new Complex Chronic Disease Program (CCDP) in June. (canlyme.com)
Listen to one of the most rational conversations with an MD about Lyme Disease that we have heard in a while. (canlyme.com)
The notion that there has never been a confirmed case from someone in Alberta who has not traveled is a mute point in that few people were truly investigated for Lyme Disease. (canlyme.com)
Asch ES, Bujak DI, Weiss M, Peterson MGE, and Weinstein A. Lyme Disease: an infectious and postinfectious syndrome. (visavissymposiums.org)
Bankhead T and Chaconas G. The role of VlsE antigenic variation in the Lyme disease spirochete: persistence through a mechanism that differs from other pathogens. (visavissymposiums.org)
Global challenges in diagnosing and managing Lyme disease-closing knowledge gaps. (visavissymposiums.org)
Patients2
Patients with chronic septic Lyme arthritis of the knee for seven years, despite multiple antibiotic trials and synovectomies. (visavissymposiums.org)
97 patients who had been treated with antibiotics for extended periods of time and had symptoms of chronic Lyme were PCR-positive. (visavissymposiums.org)
Evidence1
The following is a list of over 700 peer reviewed articles that support the evidence of persistence of Lyme and other tick-borne diseases. (visavissymposiums.org)