• Treatment options for metastatic breast cancer include systemic therapies (chemotherapy, hormone therapy), surgery, and/or radiation [ 4 ]. (biomedcentral.com)
  • Systemic therapies are the recommended primary treatment option for patients with metastatic breast cancer, while surgery is generally considered, if appropriate, after initial systemic therapy [ 4 ]. (biomedcentral.com)
  • The Auckland Advanced Breast Cancer Review (AABC) was a review of patients diagnosed with advanced inoperable/metastatic breast cancer (ABC) within the Auckland region of New Zealand, commissioned in response to a Breast Cancer Registry report (BCFNZR) that showed poor and inequitable survival outcomes. (hindawi.com)
  • In the current study, we aimed to investigate the effects of concurrent PPIs on palbociclib and ribociclib efficacy in terms of progression free survival in metastatic breast cancer (mBC) patients. (researchsquare.com)
  • Insa A, LLuch A, Prosper F, Marguan I, Marginez-Agullo A, Garcia-Conde J. Prognostic factors predicting survival from first recurrence in patients with metastatic breast cancer: analysis of 439 patients. (aaem.pl)
  • Patients with suspected diagnosis of locally recurrent or metastatic breast cancer, either at first relapse or after successive disease progressions, who had an appropriately preserved sample from a primary tumor and were scheduled for a biopsy of the recurrent lesion, were included. (springer.com)
  • Most TNBC patients with residual disease will receive adjuvant radiotherapy and/or chemotherapy, and recent work has shown that adjuvant therapy may influence ctDNA status in patients with residual disease 11 . (nature.com)
  • In the past decade, several randomized trials and meta-analyses have displayed improvements in local control and overall survival with postmastectomy radiotherapy (PMRT) for locally advanced breast cancer, but have failed to report age-specific results. (oncolink.org)
  • During the 50 years, radical mastectomy alone compared with radical mastectomy plus adjuvant radiotherapy is associated with a significantly higher cure rate, and higher survivals regardless of whether the death was from breast cancer, second cancer, benign causes or any causes. (scirp.org)
  • Radiotherapy to breast cancer may adversely affect not only mortality from breast cancer, but mortalities unrelated to breast cancer. (scirp.org)
  • Current treatment methods for breast cancer include invasive surgical procedures, radiotherapy, hormone therapy and chemotherapy. (amrita.edu)
  • Patients from the intervention groups of two separate randomized controlled trials were included: patients with breast cancer receiving neoadjuvant chemotherapy (n=74) and patients with locally advanced prostate cancer receiving treatment with radiotherapy (n=75). (jmir.org)
  • Some patients with breast cancer develop local recurrence after breast-conservation surgery despite postoperative radiotherapy, while others remain free of local recurrence even in the absence of radiotherapy. (lu.se)
  • The ROC-area for distinguishing patients that develop local recurrence from those that remain local-recurrence-free in the absence of radiotherapy was 0.66 (combined estrogen-receptor-positive/ estrogen-receptor-negative). (lu.se)
  • A highly distinct gene-expression profile for patients developing local recurrence after breast-conservation surgery despite radiotherapy has been identified. (lu.se)
  • The most commonly used treatment methods for breast cancer include surgery, radiotherapy and chemotherapy. (wikipedia.org)
  • Quantitative, quasi-experimental, pre-and post-test study, conducted with 25 women with breast cancer undergoing radiotherapy at an Oncology Center in the South of Minas Gerais, between July 2019 and March 2020. (bvsalud.org)
  • 5 Years Local Recurrencce Rates Following Post- Operative 2D Radiotherapy Treatment Planning Patients - An Institutional Experience. (who.int)
  • Methods and Materials: We have selected 198 patients treated for post-operative 2D Radiotherapy treatment planning from September 2009-September 2010. (who.int)
  • All patients had been treated with 2D conventional Radiotherapy treatment plan with tangential fields and supraclavicular and axillary fields according to histopathology report. (who.int)
  • We did a randomised, open-label phase 3 KRISTINE trial in 68 Translational Research In Oncology centres (hospitals and specialty cancer centres in Asia, Europe, USA, and Canada). (nih.gov)
  • Zoledronic acid treatment improves QOL, a primary goal of treatment in palliative oncology as it constitutes the international standard for patients with bone metastases from breast cancer. (iiarjournals.org)
  • In order to Department of Surgical Oncology, Erasmus MC Cancer improve cosmetic outcome following BCT, multiple Institute, PO Box 5201, 3008 AE Rotterdam, The Netherlands 123 2088 World J Surg (2018) 42:2087-2093 studies have focused on (preoperative) radiological imag- measurement where those scheduled for BCT were eligible ing to predict or improve the cosmetic outcome [4, 5]. (deepdyve.com)
  • The joint research will be led by Professors Ichiro Kinoshita, MD, PhD at the Division of Clinical Cancer Genomics/Department of Medical Oncology and Masato Takahashi, MD, PhD at the Department of Breast Surgery, Hokkaido University Hospital. (businesswire.com)
  • The team working in this field is led by Cristina Saura, PhD, who is also head of the Breast Cancer Group at the Vall d'Hebron Institute of Oncology (VHIO). (medscape.com)
  • The authors analyzed a database of patients with a confirmed diagnosis of BC who were referred for a neuro-oncology consultation at the National Cancer Institute in Mexico City, Mexico , from June 2009 to June 2017. (bvsalud.org)
  • survival analysis, breast neoplasms, surgery. (medigraphic.com)
  • Zielinski J, Jaworski R, Irga-Jaworska N, Haponiuk I, Jaskiewicz J. The significance of ductoscopy of mammary ducts in the diagnostics of breast neoplasms. (aaem.pl)
  • The diagnosis of breast neoplasms usually represents an emotional burden, and it may lead to adjustment reactions and even be the trigger for affective disorders (mainly depression), anxiety or psychosis. (bvsalud.org)
  • 4 Mammary neoplasms make demands on women's physical and psychological aspects, 5 and within the analysis of the patients' surgical and adjuvant treatment the impact on their mental health should be emphasized 6 . (bvsalud.org)
  • Breast cancer is one of the leading malignant neoplasms in women. (bvsalud.org)
  • The addition of adjuvant chemotherapy with capecitabine in TNBC patients with residual disease has been shown to improve outcomes, though many patients still experience disease recurrence despite the addition of adjuvant chemotherapy, and this approach may lead to overtreatment in some patients since not all patients with residual disease experience a recurrence 4 , 5 . (nature.com)
  • One of these risk-stratifying tools, the residual cancer burden (RCB) classification, quantitates the extent of residual disease in the breast and axillary lymph nodes following neoadjuvant chemotherapy and adds prognostic value to the binary assessment of pathological complete response vs. residual disease in predicting long-term survival 6 , 7 . (nature.com)
  • With increasing use of neoadjuvant chemotherapy in this population, a recent retrospective review has suggested continued improvement to local control and cancer specific survival over all age groups. (oncolink.org)
  • This retrospective review of the experience of MD Anderson Cancer Center was conducted to evaluate the effect of PMRT after neoadjuvant chemotherapy in young patients. (oncolink.org)
  • 35 years old who received neoadjuvant chemotherapy and mastectomy for Stage IIb to III breast cancer. (oncolink.org)
  • At present, recommendations regarding PMRT in patients receiving neoadjuvant chemotherapy for breast cancer are unclear. (oncolink.org)
  • Previous retrospective analysis of PMRT in the setting of neoadjuvant chemotherapy with patients of all ages did not reveal a benefit in Stage IIb disease. (oncolink.org)
  • We did a phase 3 trial to assess a neoadjuvant regimen for HER2-positive breast cancer that replaces traditional systemic chemotherapy with targeted treatment. (nih.gov)
  • Treatment patterns including receipt of surgery, radiation, chemotherapy, aromatase inhibitors (AI), and non-AI hormonal therapy were evaluated for study cohort patients with at least 2 months of follow-up. (biomedcentral.com)
  • Approximately 57% of study patients with 2+ months of follow-up received chemotherapy and over 62% received an AI during follow-up. (biomedcentral.com)
  • Endocrine therapy is the preferred treatment for patients with stage III or IV hormone-receptor-positive (HR +, which includes ER and/or PR positive) breast cancer, but chemotherapy may also be recommended for cases with rapidly progressive disease [ 4 , 5 ]. (biomedcentral.com)
  • In the subset of 886 chemotherapy-naive women treated with tamoxifen, those treated with tamoxifen for less than 1 year had a substantially higher breast cancer mortality rate than those exposed 5 years or more (adjusted HR=6.26, 95% CI, 3.10 to 12.64). (healthpartners.com)
  • In patients with breast cancer receiving adjuvant 5-fluorouracil/epirubicin/cyclophosphamide followed by docetaxel (FEC-D), we evaluated the impact of chemotherapy total cumulative dose (TCD), and early (FEC) versus late (D only) dose reductions, on survival outcomes. (jnccn.org)
  • Women with stage I-III, hormone receptor-positive/negative, HER2-negative breast cancer treated with adjuvant FEC-D chemotherapy from 2007 through 2014 in Alberta, Canada, were included. (jnccn.org)
  • Treatment of early-stage breast cancer with adjuvant chemotherapy has improved survival. (jnccn.org)
  • For the treatment of breast cancer, some patients undergo chemotherapy, radiation therapy, or hormone therapy. (frontiersin.org)
  • Patients completed questionnaires during chemotherapy. (ons.org)
  • Nurses should work closely with AA women with breast cancer undergoing chemotherapy to help them identify and consciously use coping strategies associated with increased coping capacity. (ons.org)
  • Researchers suggest that psychological distress (depression, anxiety, emotional and cognitive functioning) and symptoms (pain, fatigue, nausea and vomiting) are the most common distressing adverse effects experienced by women treated for breast cancer with IV chemotherapy (Henderson et al. (ons.org)
  • 2015). The negative effects experienced by AA women with breast cancer during chemotherapy may be reduced by teaching them how to cope effectively and avoid poor or negative coping behaviors or strategies. (ons.org)
  • or that examined the relationship between coping capacity and coping strategies, religious coping, and spiritual well-being associated with breast cancer and chemotherapy treatment (Huo et al. (ons.org)
  • The effects of adjuvant chemotherapy on the breast cancer disease seem to be as good for pre and postmenopausal patients, at least for hormone receptor negative patients. (diva-portal.org)
  • PD-L1 IHC positivity and abundance of tumor infiltrating lymphocytes were of positive prognostic value in univariable regression analyses in patients treated with (neo)adjuvant chemotherapy, where it was strongest for 22C3 CPS ≥ 10 and distant relapse-free interval (HR = 0.18, p = 0.019). (lu.se)
  • All patients underwent chemotherapy either Induction chemotherapy following surgery or chemotherapy after surgery. (who.int)
  • 46 (23%) patients were diagnosed with LABC, and had undergone chemotherapy first for downstage of the disease. (who.int)
  • In general, cancer recurrence and metastasis are the result of the interactions of multiple mutated genes. (nature.com)
  • Interestingly, the metastasis free interval (mFI: 30 months) amongst patients who developed metastatic relapse after early breast cancer was similar to international standards. (hindawi.com)
  • With approximately 18,000 new cases of BC diagnosed in Polish women annually, breast cancer liver metastasis (BCLM) is respectively an increasing issue. (aaem.pl)
  • One patient (9.1%) presented an extrahepatic lesion - bone metastasis. (aaem.pl)
  • Breast carcinoma: pattern of recurrence and metastasis after mastectomy. (aaem.pl)
  • Bone is the most common site for metastasis in breast cancer, and patients with advanced breast cancer are at high risk for developing bone metastases and experience skeletal complications ( 2 , 3 ). (iiarjournals.org)
  • Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
  • Some of these treated patients experience disease relapse and metastasis. (wikipedia.org)
  • To stage cancer, the American Joint Committee on Cancer first places the cancer in a letter category using the tumor, nodes, metastasis (TNM) classification system. (medscape.com)
  • Identification of risk factors for central nervous system metastasis in patients with breast cancer with neurologic symptoms. (bvsalud.org)
  • The current study was performed to identify factors that are present at the time of breast cancer (BC) diagnosis that are associated with a higher rate of central nervous system metastasis (CNSm). (bvsalud.org)
  • Brain metastasis is a dreaded complication that significantly reduces the quality of life in breast cancer patients . (bvsalud.org)
  • The data of breast cancer patients with brain metastasis who were treated with WBRT using cobalt -60 equipment between 2005 and 2009 were retrospectively collected from the departmental medical record unit. (bvsalud.org)
  • WBRT is an effective treatment modality for patients with brain metastasis in our resource -poor environment . (bvsalud.org)
  • Conclusion: Local recurrence after treatment of breast cancer with mastectomy+radiotherapy+/-systemic therapy is associated with a significantly higher risk of distant metastasis and death. (who.int)
  • A single normal cell randomly acquires a series of mutations that allows it to proliferate and to be transformed into a cancer cell (i.e., founding clone), which initiates tumor progression and recurrence. (nature.com)
  • Hence, pre-existing germline variants provide a profound constraint on the evolution of tumor founding clones and subclones and therefore have a contingent effect on the genetic makeup of tumor and presumably patient outcomes. (nature.com)
  • Most patients carry a missing or damaged p53 gene, a tumor suppressor whose activity is impaired in almost 50% of all cancers. (nature.com)
  • We aim to investigate the impact of circulating tumor DNA (ctDNA) status and residual cancer burden (RCB) class on outcomes in TNBC patients with RD. We analyze end-of-treatment ctDNA status in 80 TNBC patients with residual disease who are enrolled in a prospective multisite registry. (nature.com)
  • Murine breast carcinoma models suggest disruption of ST2 signaling may enhance the anti-tumor immune response, suggesting IL-33 impedes anti-tumor immunity. (frontiersin.org)
  • We detected the expression of IL-33 in tumor tissue, and IL-33 and its related cytokines in serum from BC patients. (frontiersin.org)
  • Recent insights into the cancer development mechanisms have revealed that immune system functionally regulates development and progression of epithelial malignancies and tumor-infiltrating leukocytes may be causal players in cancer development ( 2 ). (frontiersin.org)
  • In this study, we aim to determine the serum level and to detect the expression of IL-33 in human tissues in patients with breast carcinoma, using Luminex-based measurements and immunohistochemistry, to further explore the role of IL-33 in anti-tumor immunity in BC. (frontiersin.org)
  • Automated administrative databases, medical records, and tumor registries were used to identify women aged 65 years or older who received BCS or mastectomy to treat stage I or II breast cancer diagnosed from January 1, 1990, through December 31, 1994. (healthpartners.com)
  • Besides the socio-demographic variables, it was analyzed: Affected breast, Tumor location, Histological type, Clinical state at the moment of the operation and surgical technique used. (medigraphic.com)
  • 10 excised LN. LNR was in both, uni-and multivariable, analysis a highly significant prognostic factor for RFS and OAS in both subgroups of pN + patients with less respective more than 10 excised LN. Multivariable COX regression analysis was adjusted by age, tumor size, intrinsic sub types and guideline adherent adjuvant systemic therapy. (biomedcentral.com)
  • With HER2+ and triple negative tumor biology patients are considered at a higher risk for recurrence. (biomedcentral.com)
  • 26,824 reporters) on 143 patients with lymph-node-negative disease and tumor-free margins. (lu.se)
  • Oncologists altered their treatment plans in 31 % of patients whose tumor subtype had changed. (springer.com)
  • Reasons for these discrepancies may include the possibility that the molecular profile of breast cancers evolves over time and that biomarkers are heterogeneously expressed within the tumor [ 4 ] and technical inconsistencies in both tissue processing and sample evaluation. (springer.com)
  • Being aware of the benefits that the correct systemic therapy provides to patients with advanced breast cancer, the Spanish Breast Cancer Research Group (GEICAM) performed a prospective, observational study to determine the conversion rate of receptor status (ER, PR and HER2) between the primary tumor and the recurrent lesion. (springer.com)
  • The aggressive progression and recurrence of this disease has been attributed the presence of a subset of tumor cells known as breast cancer stem cells (BCSCs). (wikipedia.org)
  • For example, it has been shown that CD44+/CD24- tumor cells in the breast primary tumors associated with the presence of distance metastases. (wikipedia.org)
  • The present study aimed to investigate the possibility of using dual-energy computed tomography (CT) before therapy to discriminate between normal breast tissue and tumor tissue in patients with breast cancer, without the need to use a contrast medium. (scirp.org)
  • In all conditions, regardless of contrast medium, the CT values of tumor tissues were higher than those of normal breast tissue, indicating the effectiveness of dual-energy CT (DE-CT) in the diagnosis of breast cancer. (scirp.org)
  • There have only been a few reports regarding CT examination of breast cancer, and it is expected this study encourage the development of DE-CT imaging to improve tumor detection in patients with breast cancer. (scirp.org)
  • The presence of high expressing epithelial cell adhesion molecule (EpCAM high ) circulating tumor cells (CTC) enumerated by CellSearch ® in blood of cancer patients is strongly associated with poor prognosis. (oncotarget.com)
  • A growing interest lies in the RNA-based method, which can simultaneously investigate the tumor microenvironment and HER2 expression levels. (businesswire.com)
  • The results of a study recently published in Cancer Discovery show, for the first time, that breast milk from breast cancer patients contains circulating tumor DNA (ctDNA) that can be detected by a liquid biopsy of the milk. (medscape.com)
  • She was worried that she had transmitted the tumor through her breast milk to her second daughter while breastfeeding. (medscape.com)
  • In the end, when we analyzed the patient's breast milk, we found DNA with the same mutation that was present in her tumor," explained Saura. (medscape.com)
  • We were able to detect tumor mutations in milk samples from 13 of the 15 patients with breast cancer who were tested, while circulating tumor DNA was detected in only one of all the blood samples that were collected at the same time," said Vivancos. (medscape.com)
  • As to the potential advantages that breast milk liquid biopsy could have over similar techniques like blood liquid biopsy, Vivancos pointed to the results of her study: "We have seen that breast milk liquid biopsy was positive for the presence of circulating tumor DNA in 87% of cases, whereas blood only revealed the presence of this marker in 8% of cases. (medscape.com)
  • The letter T is followed by a number from 0 to 4, which describes the size of the tumor and whether it has spread to the skin or chest wall under the breast. (medscape.com)
  • Higher T numbers indicate a larger tumor and/or more extensive spread to tissues surrounding the breast. (medscape.com)
  • Survival analysis was performed using the Kaplan‑Meier method with statistical SPSS 18.0 software. (spandidos-publications.com)
  • ABSTRACT The 5-year survival rate of female breast cancer cases in Jordan and some of the factors that affected survival were measured. (who.int)
  • Few studies have evaluated survival, treatment, resource use, and costs among women with stage IV ER + breast cancer (BC) who did not receive HER2 targeted therapy. (biomedcentral.com)
  • Assuming that in all patients follow-up was terminated at 50 or 25 years after diagnosis, likelihood ratio test and stratified Log-rank tests were performed to evaluate the differences in cure rate and overall survival between the two cohorts. (scirp.org)
  • as compared with the standard methods of survival analysis, it requires a much longer follow-up time in order to distinguish between cure and delayed death from the cancer. (scirp.org)
  • Of the 388 patients that met inclusion criteria for this study, median overall survival (medOS) was 18.9 months in the total population, with no difference between patients with de novo metastatic disease (dnMBC -18.9 m) and recurrent metastatic disease (rMBC -18.7 m). (hindawi.com)
  • While treatment uptake and survival outcomes were generally comparable across ethnicity and district health boards, dnMBC survival outcomes were considerably poorer than expected, earmarking this subset of patients with ABC for more in-depth research. (hindawi.com)
  • Central to the report was a survival analysis of ABC cases registered in the Breast Cancer Foundation National Registry (BCR) between the year 2000-2015. (hindawi.com)
  • This inequity was reflected in the BCFNZR, where Maori had the poorest survival outcomes amongst patients with ABC compared to all other ethnicities in NZ, with a medOS of only 12.8 months. (hindawi.com)
  • CONCLUSIONS: Our findings indicate that older women receiving BCS alone have higher rates of breast cancer death than those receiving BCS + RT or mastectomy and that the survival benefit from tamoxifen increases with increasing duration of treatment. (healthpartners.com)
  • 85% for historical regimens (ie, cyclophosphamide/methotrexate/fluorouracil) are known to affect breast cancer survival. (jnccn.org)
  • 85% for adjuvant FEC-D affects breast cancer survival. (jnccn.org)
  • It has been said that African patients present late with aggressive tumors and face a lack of therapeutic options, resulting in short survival duration. (karger.com)
  • To characterize the survival of patients with breast cancer at ten years of surgery. (medigraphic.com)
  • A number of 196 patients operated for breast cancer were analyzed by the Kaplan-Meier method over a period of ten years of survival after surgery. (medigraphic.com)
  • The highest average survival was found in patients aged between 71-80 and over 80 years who had a lobular carcinoma, who had tumors in clinical stage IIa and who were subject to radical mastectomies. (medigraphic.com)
  • The group of patients object of study showed an elevated global survival, which was mainly associated to older ages, the early diagnosis of the disease and the performance of radical surgery. (medigraphic.com)
  • The incidence and 10-year survival of interval breast cancers in Wales. (medigraphic.com)
  • Does the number of removed axillary lymphnodes in high risk breast cancer patients influence the survival? (biomedcentral.com)
  • Is there a survival benefit for breast cancer patients with 3 or more positive LN (pN3+) and with more than 10 removed LN? (biomedcentral.com)
  • Uni-and multivariable analyses for recurrence free survival (RFS) and OAS showed no significant survival benefit when removing more than 10 lymph nodes even for high-risk patients. (biomedcentral.com)
  • The removal of more than 10 LN did not result in a significant survival benefit even in high risk pN + breast cancer patients. (biomedcentral.com)
  • therefore, three-year survival was 36.4% (4 patients). (aaem.pl)
  • Oncological centres should assess BCLM patients more openly and qualify them for hepatic resection along with adjuvant systemic treatment in order to improve overall survival. (aaem.pl)
  • Resection of Single Metachronous Liver Metastases from Breast Cancer Stage I-II Yeld Excellent Overall and Disease-Free Survival. (aaem.pl)
  • The aims of the study are to compare male and female breast cancer (FBC) in terms of cancer clinical and anatomopathological features and treatment approach, and to identify differences between male BC and FBC in terms of survival. (mdpi.com)
  • The beneficial effect on cause-specific survival of screening mammography in women aged 50-60 years has been shown in all studies that compared screening with no screening for breast cancer. (medscape.com)
  • We evaluated associations of race, primary payer at diagnosis, and survival among patients diagnosed in Florida with lung cancer (n = 148,140) and breast cancer (n = 111,795), from 1996 through 2007. (cdc.gov)
  • No survival association was found for Native American compared with white lung cancer patients or those using the Indian Health Service versus private insurance in fully adjusted models. (cdc.gov)
  • However, limited research has documented associations among Native American race, use of IHS, and survival time after cancer diagnosis (4). (cdc.gov)
  • In this study, we used the Florida Cancer Data System (FCDS), a Florida population-based cancer registry, to examine breast and lung cancer survival by Native American race and IHS use for the Seminole and the Miccosukee tribes, the 2 federally recognized tribes in Florida. (cdc.gov)
  • The primary outcome of our study, overall survival, was elapsed time from diagnosis to date of death or last patient encounter. (cdc.gov)
  • We excluded non-Florida residents aged 18 years or younger, patients with missing values for survival time, and patients with carcinoma in situ. (cdc.gov)
  • Cancer incidence and survival are clearly linked to socioeconomic factors. (who.int)
  • Purpose: Radiation therapy (RT) after breast-conserving surgery reduces locoregional recurrences and improves survival but may cause late side effects. (lu.se)
  • A study of survival cancers are treated at the breast health centre in Algiers. (who.int)
  • A large of registered cancer cases of breast, colon, rectum, large bowel, new Cancer Centre is now being implemented in Sétif, and is and prostate during 1990-1994 has been carried out within the expected to provide care for all cancer patients from the area of CONCORD Survival study. (who.int)
  • A limited number of biomarkers have been used to predict the prognosis and monitor the outcomes of patients with breast cancer (BC), such as lactate dehydrogenase (LDH), which is an independent prognostic marker for BC and the Ki-67 index, which is of utmost importance to the prognosis and molecular typing of patients with BC ( 1 ). (spandidos-publications.com)
  • Germline variants such as BRCA1/2 play an important role in tumorigenesis and clinical outcomes of cancer patients. (nature.com)
  • The challenge remains in using these inherited germline variants to predict clinical outcomes of cancer patient population. (nature.com)
  • Hence, germline genomic information could be used for developing non-invasive genomic tests for predicting patients' outcomes in breast cancer. (nature.com)
  • 9 Here we reasoned that the collective impact of germline variants in cancer patients might largely determine tumorigenesis, evolution, and even clinical outcomes. (nature.com)
  • The purpose of this study was to investigate the combined impact of EOT ctDNA status and RCB class on outcomes in TNBC patients with residual disease. (nature.com)
  • Paucity of data has curtailed efforts to improve ABC patient outcomes in NZ. (hindawi.com)
  • Maori health outcomes have historically lagged behind non-Maori across a range of cancer and noncancer related indicators [ 7 ]. (hindawi.com)
  • Conversely, early reductions (FEC±D) negatively affected patient outcomes. (jnccn.org)
  • A variety of barriers can limit physical rehabilitation outcomes, and patients may benefit from more support during this time. (jmir.org)
  • The current analysis revealed different gene set enrichment patterns in tumors of AS compared with CA and AA, which may contribute to differential clinical outcomes and highlights the importance of including patients of Asian ancestry in genomic BC research. (agendia.com)
  • As genomic profiling data are not widely available for Asian American BC patients, further analyses including follow-up data are warranted to evaluate clinical outcomes and identify appropriate therapeutic strategies. (agendia.com)
  • It has been reported that long-term acid suppression by PPIs reduces the antitumor efficacy of pazopanib and capecitabine, while this effect of PPIs has not been found in clinical outcomes on patients treated with epidermal growth factor receptor (EGFR) thyrosine kinase inhibitors [6-8]. (researchsquare.com)
  • Using mobile technology for symptom management and self-care can improve patient-clinician communication and clinical outcomes in patients with cancer. (jmir.org)
  • We have previously shown that the Gene expression Grade Index (GGI) was able to identify two subtypes of estrogen receptor (ER)-positive tumors that were associated with statistically distinct clinical outcomes in both untreated and tamoxifen-treated patients. (biomedcentral.com)
  • BostonGene, NEC Corporation and Japan Industrial Partners recently announced the formation of BostonGene Japan Inc., a Tokyo-based joint venture to advance personalized medicine and dramatically improve patient outcomes. (businesswire.com)
  • However, few longitudinal studies have examined employment outcomes in women with early-stage breast cancer. (cdc.gov)
  • The purpose of this study was to examine employment trajectories in a cohort of early-stage breast cancer patients from treatment to 2-year follow-up, and evaluate relationships between sociodemographic, clinical/treatment, and psychosocial factors and employment outcomes. (cdc.gov)
  • Methods: Data from a cohort study of newly diagnosed early-stage breast cancer patients were used to examine employment outcomes among 347 working-age patients, 40-64 years old. (cdc.gov)
  • Data from a 6-month cohort study of 100 breast cancer patients initiating AI therapy and of 200 women of a similar age without a history of cancer were analyzed. (nih.gov)
  • A comparison cohort without cancer was created from the SEER 5% Medicare sample and matched 1:1 to the study cohort based on age, sex, and race. (biomedcentral.com)
  • BACKGROUND: The purpose of this study was to compare the rates of all-cause and breast cancer-specific mortality after breast-conserving surgery (BCS) only, BCS plus radiation therapy (RT), mastectomy, and the receipt of adjuvant tamoxifen in a large population-based cohort of older women with early-stage disease. (healthpartners.com)
  • A retrospective database analysis of the multi center cohort database BRENDA (breast cancer under evidence based guidelines) with data from 9625 patients from 17 breast centers was carried out. (biomedcentral.com)
  • companion IHC diagnostic assays for atezolizumab and pembrolizumab, respectively) in a population-based cohort of 232 early-stage TNBC patients. (lu.se)
  • We therefore examined factors associated with =5% weight gain over 2-year follow-up of a cohort of newly diagnosed early-stage invasive breast cancer (EIBC) and ductal carcinoma in situ (DCIS) patients and age-matched controls without a breast cancer history. (cdc.gov)
  • For a cohort of patients (n = 157) with accessible computed tomography-based 3-dimensional treatment plans in Dicom-RT format, dose-volume descriptors for organs at risk were derived. (lu.se)
  • In addition, these were compared with dose-volume data for a cohort of patients treated with contemporary RT techniques. (lu.se)
  • By calculating these parameters, Boag estimated the probability of cure for several tumors including cancer of the breast. (scirp.org)
  • Patients of Asian ancestry are underrepresented in US registries, and few studies have characterized tumors molecular profiles for these patients. (agendia.com)
  • In the current analysis, we assess clinical, pathological, and molecular profiles from self-reported Asian breast cancer patients (AS), in comparison with age-matched Caucasian (CA) and African American patients (AA), to evaluate the influence of Asian ancestry on differential gene expression in breast tumors. (agendia.com)
  • Upregulation of immune gene sets in AS patient tumors suggests that future studies utilizing immune cell deconvolution analysis may be informative. (agendia.com)
  • Male breast cancer (BC) represents less than 1% of male tumors. (mdpi.com)
  • The objective of this study was to determine the conversion rate of human epidermal growth factor receptor 2 (HER2), estrogen receptor (ER) and progesterone receptor (PR) between primary tumors and metastatic lesions in advanced breast cancer. (springer.com)
  • Recently, the 12th St Gallen International Breast Cancer Conference Expert Panel recommends that the subtype classification of breast cancer, namely 'HR positive' (including 'luminal A' and 'luminal B' tumors), 'HER2 amplified' and 'triple negative,' should guide the treatment plan for breast cancer patients. (springer.com)
  • Cancer stem cells in breast tumors were first discovered in 2003. (wikipedia.org)
  • As a result, primary breast cancer tumors quickly form metastases in distant sites. (wikipedia.org)
  • Pleural metastases from breast cancer patients were enriched with CD44+/CD24- cells, indicative of a higher enrichment of BCSCs in these resistant tumors. (wikipedia.org)
  • The following patient data were extracted by interview and from the hospital's radiology information system: height, weight, age, menstrual cycle, CT images of normal tissue and tumors with or without contrast medium, and the histopathological diagnosis of the aspiration biopsy. (scirp.org)
  • Most breast cancer patients whose tumors express the estrogen receptor (ER) receive endocrine therapy. (biomedcentral.com)
  • As for this unresolved need, Saura explained that there is currently no system or tool available to allow early suspicion of breast tumors in pregnant women prior to diagnosis. (medscape.com)
  • End-of-treatment ctDNA is detectable in one-third of TNBC patients with residual disease after NAST. (nature.com)
  • Although standard multi-modality treatment has improved the overall outcome and quality of life for patients with BC, identification of new prognostic markers, therapeutic targets, and new therapeutic approaches are needed. (frontiersin.org)
  • SRs/meta-analyses that explored the effects of exercise interventions on CRF in breast cancer patients compared with the routine methods of treatment and care were retrieved from nine databases. (springer.com)
  • The incidence of CRF in breast cancer patients is higher than that in other types of cancers [ 1 ], among which up to 33% of patients experience fatigue five years after the end of breast cancer treatment [ 8 ]. (springer.com)
  • however, some patients remain at risk of relapse or death for many years after treatment of early-stage disease. (nih.gov)
  • Between June 25, 2014, and June 15, 2015, we randomly assigned 444 patients to neoadjuvant treatment with trastuzumab emtansine plus pertuzumab (n=223) or docetaxel, carboplatin, and trastuzumab plus pertuzumab (n=221). (nih.gov)
  • To examine self-reported menopausal-type symptoms among breast cancer patients on aromatase inhibitors (AIs) compared to women of the same age who had not been diagnosed with cancer, and to determine whether the percentage of breast cancer patients experiencing these symptoms changed over the first 6 months of AI treatment. (nih.gov)
  • Because bothersome symptoms and side-effects are a major reason for discontinuation and non-adherence to treatment, symptoms should be monitored and addressed by oncologists so that the breast cancer patient can maintain her quality of life and remain adherent to the treatment schedule. (nih.gov)
  • Evidence on treatment from prospective randomized trials that address the specific characteristics of African patients is lacking. (karger.com)
  • The decision making process for axillary dissection has changed in recent years for patients with early breast cancer and positive sentinel lymph nodes (LN). The question now arises, what is the optimal surgical treatment for patients with positive axillary LN (pN+). (biomedcentral.com)
  • We enrolled hormone receptor-positive, HER2-negative mBC patients treated with endocrine treatment (Letrozole or fulvestrant) combined palbociclib or ribociclib alone or with PPI accompanying our observational study. (researchsquare.com)
  • During palbociclib/ribociclib therapy, patients should be treated with 'concurrent PPIs' defined as all or more than half of treatment with palbociclib/ribociclib, if no PPI was applied, it was defined as 'no concurrent PPI', those who used PPI but less than half were excluded from the study. (researchsquare.com)
  • Our study included 217 patients, 105 of whom received palbociclib and 112 received ribociclib treatment. (researchsquare.com)
  • For this reason, drug-drug interactions (DDIs) at the time of absorption should be considered as one of the causes of treatment failure in cancer patients [2]. (researchsquare.com)
  • The clinical efficacy of the combination of a CDK 4/6 inhibitor with aromatase inhibitors or fulvestrant has been acknowledged as the invention therapy in the first-second line treatment of human epidermal growth factor receptor 2 (HER2) negative hormone receptor positive premenopausal and postmenopausal women with advanced breast cancer [10-13]. (researchsquare.com)
  • The interactive app Interaktor has been shown to reduce symptom burden during cancer treatment. (jmir.org)
  • This study aimed to describe engagement with the Interaktor app among patients with breast or prostate cancer during treatment. (jmir.org)
  • Requests were made for advice on diet and psychological symptoms, as well as for more comprehensive and detailed information as the patient progressed through treatment. (jmir.org)
  • The aim of study was to evaluate surgical treatment in patients with isolated BCLM. (aaem.pl)
  • These results reinforce the recommendation for performing confirmatory biopsies of metastases, not only to avoid misdiagnosis of breast cancer relapse, but also to optimize treatment (clinicaltrials.gov identifier: NCT01377363). (springer.com)
  • Some of these gaps have been addressed in prior work conducted by a multidisciplinary research team, including the authors of this letter, within the N-MALE study ("Male breast cancer: patients' needs in prevention, diagnosis, treatment, rehabilitation, and follow-up care") that was funded by the German Cancer Aid between 2016 and 2018. (karger.com)
  • Background: We assessed the effect of zoledronic acid on quality of life (QOL) and pain outcome in breast cancer patients with bone metastases using the European Organization for Research and Treatment of Cancer bone metastases module (EORTC QLQ-BM22). (iiarjournals.org)
  • Conclusion: Zoledronic acid treatment improved QOL of breast cancer patients with bone metastases by relieving bone pain. (iiarjournals.org)
  • Therefore, delaying the onset and/or reducing pain associated with bone metastases is an important goal in the palliative treatment of patients with bone metastases from breast cancer. (iiarjournals.org)
  • Conclusions Our preliminary results suggest that disease-free women with CRFS after successful breast cancer treatment have significantly lower subjective quality of life and mood. (bmj.com)
  • 5 Of the many symptoms associated with cancer and its treatment, fatigue is probably the most under-recognised and poorly managed. (bmj.com)
  • Topical minoxidil can be of significant benefit to women with breast cancer who develop alopecia during treatment with endocrine therapies, our most recent research shows. (mskcc.org)
  • In this commentary, expert faculty address frequently asked questions about the current optimal treatment of patients with triple-negative breast cancer. (clinicaloptions.com)
  • If you have breast cancer, you may want to explore different treatment methods to supplement traditional medicine. (healthline.com)
  • A healthy diet is an important part of cancer treatment. (healthline.com)
  • However, research is mixed on whether antioxidant supplements are safe to use during cancer treatment. (healthline.com)
  • Acupuncture is a central part of traditional Chinese medicine that may help relieve symptoms of breast cancer and side effects of treatment. (healthline.com)
  • Breast cancer is also typically responsive to available therapies, and complete cure can be expected when it is diagnosed at an early stage and managed with appropriate treatment. (scirp.org)
  • Volume measurements are promising in outcome prediction of intended breast-conserving treatment. (deepdyve.com)
  • Cancer treatment of the elderly patients is an increasingly important concern since the risk for developing breast cancer increases with age. (diva-portal.org)
  • The aim of this study was to follow HRQOL in postmenopausal women (55−80 years) with breast cancer receiving adjuvant treatment after surgery, until five years post-treatment, and compare with a general population. (diva-portal.org)
  • Five years after completion of treatment, the patient sample experienced better HRQOL than the reference sample in all domains, supporting our hypothesis that the impact on HRQOL would have been resolved over time for these patients. (diva-portal.org)
  • All relapses (cases) were identified from patients randomized to receive monotherapy or from the switching treatment arms for whom relapse occurred before the switch. (biomedcentral.com)
  • This collaboration supports our mission to equip doctors in finding the most effective treatment options for their patients. (businesswire.com)
  • Because of early detection, intervention, and postoperative treatment, breast cancer mortality has been decreasing. (medscape.com)
  • [ 5 ] Although breast cancer was diagnosed more often in women who continued screening, that did not translate to a significant reduction in deaths because breast cancer is less successful treatment in older women. (medscape.com)
  • AHCA data contain medical records on all patients treated at hospitals and free-standing surgical and radiological treatment centers (6). (cdc.gov)
  • The mean radiation dose used for WBRT was 30 Gy in 10 fractions, and total responses recorded were 86.5% with 53.8% complete improvement in patients ' performance status 4 weeks after WBRT treatment . (bvsalud.org)
  • Materials and Methods: We interviewed participants 4-6 weeks after definitive surgical treatment (patients) or a negative/benign screening mammogram (controls). (cdc.gov)
  • Although the existing body of knowledge about cancer prevention, treatment and palliative care is extensive, more still needs to be known in many areas, notably in etiology and prevention research. (who.int)
  • Efforts to prevent and control cancer are hampered by the low priority frequently given to the disease by governments and health ministries, excessive reliance and expenditure on treatment, and a considerable imbalance between resources allocated for basic cancer research and those devoted to its prevention and control. (who.int)
  • prevention, early detection, treatment, and palliative care, as set out in WHO's guidelines for national cancer control programmes.1 A national cancer control programme can help policy-makers and programme managers make the most efficient use of available resources to benefit the whole population by taking a balanced approach to evidence-based interventions. (who.int)
  • We examined patients' employment trajectories after definitive surgical treatment, using a multivariable logistic regression model to identify factors associated with diminished (versus sustained) employment at 2-year follow-up. (cdc.gov)
  • Results: A total of 245 patients (71%) were employed at least part-time at the time of definitive surgical treatment. (cdc.gov)
  • Conclusions: Patients with elevated fatigue and African Americans patients were more likely to experience diminished employment participation after definitive surgical treatment. (cdc.gov)
  • Cancer places specific demands on individuals, with substantial stressors both at diagnosis and during treatment. (bvsalud.org)
  • The main purpose of this paper was to investigate long-term side effects after whole breast RT in a randomized clinical trial initiated in 1991 and to report dose-volume data based on individual 3-dimensional treatment plans for organs at risk. (lu.se)
  • Methods and Materials: The trial included 1187 patients with T1-2 N0 breast cancer randomized to postoperative tangential whole breast RT or no further treatment. (lu.se)
  • The observed increase in stroke mortality may partly be secondary to cardiac side effects, complications to anticoagulant treatment, or to chance, rather than a direct side effect of tangential whole breast irradiation. (lu.se)
  • Sociodemographic and clinical data were collected, the Quality-of-Life Questionnaire-Core 30 of the European Organization for Research and Treatment of Cancer (EORTC QLQ-C30) was used to assess quality of life, applied at three stages of the treatment. (bvsalud.org)
  • As breast cancer treatment is multimodality approach Radiation therapy has significant impact on prevention of local recurrence. (who.int)
  • Breast cancer is the most common invasive cancer in women and the second leading cause of death from cancer among women in the United States (US) [ 1 ]. (biomedcentral.com)
  • This meta-analysis included cohorts of self-reported AS, CA, and AA with early-stage, invasive breast cancer (EBC) prospectively enrolled in the US from 2011 to 2020 in FLEX (NCT03053193), MINT (NCT01501487), or IMPACt (NCT02670577) trials. (agendia.com)
  • During their lifetime, approximately 12% of women in the USA will develop invasive breast cancer, the second leading cause of cancer death of women in the USA [1]. (amrita.edu)
  • Breast cancer more often starts from the malfunctioning of milk-producing ducts (invasive ductal carcinoma). (jmir.org)
  • Breast cancer was classified into ductal carcinoma in situ, invasive ductal carcinoma, invasive lobular carcinoma, fibromatosis-like metaplastic carcinoma, and apocrine carcinoma. (scirp.org)
  • These ductal carcinomas are divided into either ductal carcinoma in situ (DCIS) or invasive ductal carcinoma (IDC) by the degree of invasion of cancer cells. (scirp.org)
  • Results A total of 36 patients were included, 20 and 23 for the evaluation of breast and tumour volume (ductal invasive carcinomas), respectively. (deepdyve.com)
  • A prospective study of weight gain in women diagnosed with early-stage invasive breast cancer, ductal carcinoma in situ, and women without breast cancer. (cdc.gov)
  • We have previously undertaken a systematic review of the literature regarding the prevalence of fatigue in breast cancer survivors (BCS). (bmj.com)
  • Breast cancer has traditionally been considered a Western disease, but in recent years its prevalence has been increasing annually among Japanese women as a consequence of changing lifestyles, notably with fewer marriages and more pregnancies at older ages. (scirp.org)
  • To investigate HPV genotype prevalence in BC and OSCC patients in Pretoria, South Africa (SA). (bvsalud.org)
  • The prevalence of HPV infection in BC patients was 77.2%, with 35.6% high- risk (HR) genotypes , and that in OSCC patients 90.0%, with 56.0% HR genotypes . (bvsalud.org)
  • In low-resource settings with a high prevalence of cancers induced by biological agents, special measures are needed to combat these infections. (who.int)
  • Depression prevalence in patients with cancer varies from 3% to 55% among different studies. (bvsalud.org)
  • Of all the mood complications linked to cancer, depression has been the most widely investigated, but despite many years of research, the prevalence of depression in cancer patients is still a matter of much debate. (bvsalud.org)
  • A further 20 blocks from The ISH results were given percentage vanced stages with a likely prevalence samples from normal breast tissues scores based on positive signals and of more aggressive tumour forms were labelled as a control group (i.e. number of cells that gave these signals. (who.int)
  • MATERIALS AND METHODS: Ninety women with generalized chronic periodontitis, aged 45-70 years, were studied. (who.int)
  • The Global Burden of Disease Study 2020 [ 1 ] indicated that breast cancer remains the leading cancer diagnosis among females [ 2 ]. (springer.com)
  • Breast Care (2020) 15 (4): 437-438. (karger.com)
  • Breast cancer is the most prevalent type of cancer among women globally, with 685,000 deaths recorded worldwide in 2020. (wikipedia.org)
  • Cancer;126(15): 3456-3463, 2020 08 01. (bvsalud.org)
  • It is projected that by 2020 there will be every year 15 million new cancer cases and 10 million cancer deaths. (who.int)
  • Cuantitativo, cuasiexperimental, tipo com 25 mulheres com câncer de mama submetidas à radioterapia em pre y posprueba, realizado con 25 mujeres con cáncer de mama sometidas um Centro de Oncologia do Sul de Minas Gerais, entre julho de 2019 a a radioterapia en un Centro de Oncología del Sur de Minas Gerais, entre março de 2020. (bvsalud.org)
  • We also selected articles on BC epidemiology, risk factors, clinical presentation, and cancer control in Africa. (karger.com)
  • All-cause mortality is decreased in women undergoing annual mammography before breast cancer diagnosis. (medigraphic.com)
  • Digital mammography is somewhat more sensitive in younger women and women with dense breasts, but outcome studies are lacking. (aafp.org)
  • The American Cancer Society recommends annual magnetic resonance imaging as an adjunct to screening mammography in high-risk women 30 years and older. (aafp.org)
  • Digital mammography is an option for younger women and those with denser breasts, but studies have not proven a mortality benefit. (aafp.org)
  • Magnetic resonance imaging is recommended as an adjunct to screening mammography in women 30 years and older who are at high risk for breast cancer. (aafp.org)
  • Although many physicians recommend the triad of breast self-examination, clinical breast examination, and mammography to screen women who are at average risk, recent studies and recommendations have questioned the appropriateness of each of these modalities. (aafp.org)
  • Additionally, there has been increasing attention in the medical literature and lay press regarding the use of digital mammography, magnetic resonance imaging (MRI), scintimammography, and other imaging methods to improve the sensitivity and specificity of screening. (aafp.org)
  • [ 3 ] Gotzsche and Olsen, in their meta-analysis, reviewed the methodological quality of mammography trials and challenged the efficacy of mammography in reducing mortality from breast cancer, [ 4 ] although an independent review of the meta-analysis concluded that in women aged over 50 years, the benefit from screening mammography can not be negated. (medscape.com)
  • [ 8 ] False-positive mammography increases the anxiety of patients. (medscape.com)
  • [ 9 ] Young age, dense breasts, use of estrogen-replacement therapy, family history of breast cancer and increased interval between mammography are some of the factors leading to false-positive mammography. (medscape.com)
  • [ 10 ] A poorer sensitivity of mammography in young women with dense breasts can also lead to false-negative interpretations of the mammography. (medscape.com)
  • The performance of digital mammography was no different than film-screen mammography as a whole, but was significantly better than film-screen mammography among women aged under 50 years (i.e., premenopausal, perimenopausal and women with dense breasts). (medscape.com)
  • Methods Breast volume by the 3D-US was compared to the water displacement method (WDM), mastectomy specimen weight, 3-D MRI and three different calculations for breast volume on mammography. (deepdyve.com)
  • This article assesses the diagnostic sensitivity of mammography in the preoperative detection of breast cancer in young women. (annals.edu.sg)
  • Mammography is a useful imaging technique in providing preoperative detection and diagnosis of breast carcinoma in women below 40 years of age with clinical suspicion of malignancy. (annals.edu.sg)
  • Mammography is the preferred screening examination for breast cancer. (medscape.com)
  • Screening mammography accounts for the greatest contribution to early detection and decrease in breast cancer mortality, although its use has resulted in a minor increase in the number of in situ cancers detected. (medscape.com)
  • In the UK Age trial, breast cancer mortality in the first 10 years after diagnosis was significantly lower (rate ratio [RR] 0.75) in women who received annual screening mammography from age 40-49 years than in those invited for screening at age 50 years and every 3 years thereafter. (medscape.com)
  • In cancer tissues, expression of IL-33 was higher than matched normal breast tissues from the same patients, and was also associated with a well-differentiated phenotype, HER2 overexpression, more lymph nodes involvement, and a family history of malignant carcinoma. (frontiersin.org)
  • Recent studies demonstrated that high serum levels of soluble ST2 (sST2) are a worse prognostic factor in hepatocellular carcinoma ( 9 ), and that serum IL-33 is a diagnostic and prognostic marker in non-small cell lung cancer, independent of the therapeutic intervention ( 10 ). (frontiersin.org)
  • We retrospectively reviewed 1010 women with breast carcinoma between January 1996 and September 2002. (annals.edu.sg)
  • Little has been reported on the association between HPV and breast carcinoma (BC) or oesophageal squamous cell carcinoma (OSCC) in Africa . (bvsalud.org)
  • Breast carcinoma is the common- noma not otherwise specified, 17 cases sues (according to the specification of est malignancy among women in of lobular carcinoma, 5 cases of mixed the second differential kit which gave developed and developing countries ductal and lobular carcinoma and 7 the blue colour). (who.int)
  • Histological types were reviewed and the proportions of each type were compared with those found in a consecutive series of 773 breast carcinomas in women above 40 years of age seen during the same period in our hospital. (annals.edu.sg)
  • In addition to lung cancer, tobacco consumption causes tumours of the larynx, pancreas, kidney, bladder and, in conjunction with alcohol drinking, a high incidence of carcinomas of the oral cavity and the oesophagus. (who.int)
  • Conclusions 3-D US showed a high association with gold standard WDM for the preoperative assessment of breast volume and the histopathological measurement of tumour volume. (deepdyve.com)
  • Conclusions: EIBC patients were more likely than DCIS patients and controls to experience =5% weight gain over follow-up. (cdc.gov)
  • Conclusions: In this trial, serious late side effects of whole breast RT were limited and less than previously reported in large meta-analyses. (lu.se)
  • The contribution of the clinical breast examination to early detection is difficult to determine, but studies show that sensitivity is highly dependent on time taken to do the examination. (aafp.org)
  • Methods for early detection are needed, as evidenced every day in the multidisciplinary unit for treating pregnancy-associated breast cancer, which operates within the Breast Unit at the Vall d'Hebron University Hospital in Barcelona, Spain. (medscape.com)
  • As a next step to make this finding practically useful, the research team designed a genomic panel using next-generation sequencing as a potential method for early detection of breast cancer. (medscape.com)
  • Conclusion: Our findings support that the SP142 and 22C3 IHC assays, with their respective clinically applied scoring algorithms, are not analytically equivalent where they identify partially non-overlapping subpopulations of TNBC patients and cannot be substituted with one another regarding PD-L1 detection. (lu.se)
  • The detection of high-oncogenic HPV genotypes in patients with breast cancer supports the hypothesis of an etiologic role for the virus in breast cancer development. (who.int)
  • Compared with women receiving mastectomy, those receiving BCS without RT were twice as likely to die of breast cancer (adjusted hazards ratio [HR]=2.19, 95% confidence interval [CI], 1.51 to 3.18). (healthpartners.com)
  • Breast cancer mortality rates were similar between women receiving BCS plus RT and women receiving mastectomy (adjusted HR=1.08, 95% CI, 0.79 to 1.48). (healthpartners.com)
  • All patients had undergone surgery in form of mastectomy or modified radical mastectomy. (who.int)
  • Biomarkers to risk-stratify patients with RD could help individualize adjuvant therapy and inform future adjuvant therapy trials. (nature.com)
  • ctDNA status is associated with RCB class, though these two biomarkers provide complementary but not completely overlapping prognostic information, particularly in patients with RCB-II disease. (nature.com)
  • Oral contraceptive use has been suggested to influence the risk of breast, ovarian, and endometrial cancer. (aacrjournals.org)
  • 95% CI, 1.06-2.28), whereas the protective association for ovarian and endometrial cancer remained significant up to 35 years after last use of oral contraceptives. (aacrjournals.org)
  • Given the body of evidence presented in our study, we argue that oral contraceptives can dramatically reduce women's risk of ovarian and endometrial cancer, whereas their effect on lifetime risk of breast cancer is limited. (aacrjournals.org)
  • Banas T, Juszczyk G, Pitynski K, Nieweglowska D, Ludwin A, Czerw A. Incidence and mortality rates in breast, corpus uteri, and ovarian cancers in Poland (1980-2013): an analysis of population-based data in relation to socioeconomic changes. (aaem.pl)
  • Within the subgroups of patients with node-positive disease or who were treated with L, the hazard of relapse was significantly greater for patients with GGI at or above the median. (biomedcentral.com)
  • This analysis supports the GGI as a good predictor of relapse for ER-positive patients, even among patients who receive L. Validation of these results, in a larger series from BIG 1-98, is planned using the simplified GGI represented by a smaller set of genes and tested by qRT-PCR on paraffin-embedded tissues. (biomedcentral.com)
  • Gene signatures derived from the genes containing functionally germline variants significantly distinguished recurred and non-recurred patients in two ER+ breast cancer independent cohorts ( n = 200 and 295, P = 1.4 × 10 −3 ). (nature.com)
  • Resource utilization and costs (by place of service, reported per patient per month, PPPM) were compared across cohorts. (biomedcentral.com)
  • Mean age was 77 years for both cohorts, with average follow-up of 18 months for study patients and 26 months for comparison patients. (biomedcentral.com)
  • Triple-negative breast cancer (TNBC) patients with residual disease (RD) after neoadjuvant systemic therapy (NAST) are at high risk for recurrence. (nature.com)
  • To address this gaping issue, the Breast Cancer Foundation of NZ (BCFNZ) published I Am Still Here (BCFNZR) in September 2018, NZ's first comprehensive report on the state of ABC in the country [ 3 ]. (hindawi.com)
  • Patients and methods: Data from 2006 to 2018 were retrospectively acquired. (mdpi.com)
  • Koppert, L. 2018-01-03 00:00:00 Background The resection volume in relation to the breast volume is known to in﫿uence cosmetic outcome fol- lowing breast-conserving therapy. (deepdyve.com)
  • The primary objective was to compare the number of patients who achieved a pathological complete response (ypT0/is, ypN0), between groups in the intention-to-treat population (two-sided assessment), based on local evaluation of tumour samples taken at breast cancer surgery done between 14 days and 6 weeks after completion of neoadjuvant therapy. (nih.gov)
  • Within 4 months of cancer diagnosis, surgery and radiation were received by 39% and 32% of study patients, respectively. (biomedcentral.com)
  • Physiotherapy-led home rehabilitation after breast cancer surgery can protect against the development of upper limb dysfunction and other disabling consequences of surgery. (jmir.org)
  • The aims of this study were to explore patients' rehabilitation experiences and unmet needs during home rehabilitation after breast cancer surgery and to understand their experiences of mHealth technology and the requirements they desire from an mHealth system. (jmir.org)
  • There are unmet needs surrounding access to physiotherapy, information, and support during home rehabilitation after breast cancer surgery that could be addressed with an mHealth system. (jmir.org)
  • A key component of physiotherapy rehabilitation is the home exercise program (HEP), which is usually prescribed to patients on the first day after surgery. (jmir.org)
  • From nearly 2,000 liver resections performed, 11 female patients at the mean age of 59.18 years with BCLM were qualified for surgery. (aaem.pl)
  • Amounts of 49 males and 680 postmenopausal females with primary non-metastatic BC who underwent breast surgery at Mauriziano Hospital or IRCCS Candiolo (TO-Italy) were included. (mdpi.com)
  • commonly assessed in the area of breast reconstructive surgery [6]. (deepdyve.com)
  • Only 76 of 237 patients had mammograms performed prior to surgery. (annals.edu.sg)
  • Of the 76 patients who had mammograms performed prior to surgery, 81 cancers were found. (annals.edu.sg)
  • Surgery also has a limited role , except in few selected patients with oligometastasis. (bvsalud.org)
  • Sétif, provides cancer surgery the area is possible. (who.int)
  • None of the patients with breast conservation surgery had been selected. (who.int)
  • Results: 152 (77%) patients had undergone upfront Surgery. (who.int)
  • In which 6.5% (10 patients out of 152) in upfront surgery group and 15.2% (7 patients out of 46) in LABC group developed local recurrence. (who.int)
  • So, total 5% (10 patients) in upfront surgery group and 3.5% (7 patients) in LABC group out of 198 total patients developed local recurrence. (who.int)
  • Breast cancer (BC) is the most common cancer among women globally and ranks as the second leading cause of cancer death among women (after lung cancer) and, by far is the second common cancer in the world [ 1 ]. (oncotarget.com)
  • Breast cancer is the leading cause of cancer death among women in developing countries and the second leading cause of cancer death (following lung cancer) among women in developed countries. (jmir.org)
  • Incident lung cancer and female breast cancer were identified from the FCDS. (cdc.gov)
  • however, 176 lung cancer patients and 177 breast cancer patients reported using IHS providers ( Table 1 ). (cdc.gov)
  • Incidences of contralateral breast cancer and lung cancer were similar between groups. (lu.se)
  • Is there a rationale for aggressive breast cancer liver metastases resections in Polish female patients? (aaem.pl)
  • Predictive Profile-Normogram for Liver Resection for Breast Cancer Metastases: An Aggressive Approach with Promising Results Ann Surg Oncol. (aaem.pl)
  • Patients and Methods: Three hundred sixty-six breast cancer patients receiving zoledronic acid for bone metastases from 13 Centers were prospectively enrolled. (iiarjournals.org)
  • Patients with bone metastases often develop moderate to severe pain which significantly decreases functionality and quality of life (QOL) ( 4 , 5 ). (iiarjournals.org)
  • Zoledronic acid, a bisphosphonate that potently inhibiting osteoclastic activity, has been shown to significantly reduce the overall risk of skeletal complications and provide durable pain reduction in patients with bone metastases from breast cancer ( 5 - 7 ). (iiarjournals.org)
  • Patients with more than three brain deposits accounted for 71.2% of all the brain metastases . (bvsalud.org)
  • The prognosis of patients with different molecular subtypes of BC may be associated with the different Ki‑67 index. (spandidos-publications.com)
  • These studies have consistently shown, on the basis of hierarchical clustering of gene expression profiles, that ER-positive breast cancers can be classified into molecular subtypes (mainly luminal A and B) and that these subtypes are associated with a different clinical outcome, suggesting a molecular basis behind the clinical heterogeneity. (biomedcentral.com)
  • A multicenter FFDM trial showed sensitivity of 70% compared with 55% for conventional mammograms in women with dense breasts and aged under 50 years. (medscape.com)
  • the results indicated that almost 80% patients succumbed during the 5 years following diagnosis. (spandidos-publications.com)
  • For example, patients suffering from Li-Fraumeni syndrome have an almost 100% chance of developing a wide range of malignancies before the age of 70 years. (nature.com)
  • 35 years old with stage II-III breast cancer treated with doxorubicin-based neoadjuvant chemothe. (oncolink.org)
  • As a result, 41 patients were followed alive longer than 50 years. (scirp.org)
  • Breast cancer incidence in Asian populations has increased in recent years (1,2). (agendia.com)
  • ML methods have evolved over the years from manual seeded inputs to automatic initializations. (jmir.org)
  • Methods Women between 3 months and 2 years after completion of any primary therapy were recruited from a cancer centre follow-up clinic. (bmj.com)
  • Two thirds of women diagnosed with breast cancer today are likely to survive for at least 20 years. (bmj.com)
  • Breast cancer incidence rates are markedly higher in Caucasian women aged 60-84 years. (ons.org)
  • However, AA women aged younger than 45 years have a higher rate of breast cancer and are more likely to die from it (American Cancer Society, 2015). (ons.org)
  • Given the higher incidence of TNBC and shorter life span (death at every age and within seven years of diagnosis) among AA women compared to non-Hispanic Caucasian and Asian women (American Cancer Society, 2015), AA women may benefit from learning how to increase their coping capacity, spiritual well-being, and use of helpful coping strategies, to descrease psychological distress and distressing symptoms. (ons.org)
  • [ 1 ] For women in their 40s, 15-year mortality from breast cancer was reduced by 20%, [ 2 ] even though mammographic screening has been shown it to be most effective after 55 years of age. (medscape.com)
  • However, very few patients older than 65 years are included in randomised studies. (diva-portal.org)
  • Of these, 237 women were below 40 years of age, accounting for 23.5% of all breast cancers. (annals.edu.sg)
  • The patients' age ranged from 25 to 40 years, with a mean of 36.4 years. (annals.edu.sg)
  • Approximately 7% of breast cancers occur below 40 years of age. (annals.edu.sg)
  • The panel has been calibrated, based on the existing literature, to detect the genes that are most frequently mutated in breast cancer in young women under 45 years old. (medscape.com)
  • In practice, the panel design allows us to detect mutations in more than 95% of breast cancer cases in women under 45 years old. (medscape.com)
  • A large-scale, population-based, observational study by García-Albéniz et al concluded that continuing annual breast cancer screening past age 75 years did not result in substantial reductions in 8-year breast cancer mortality compared with stopping screening. (medscape.com)
  • In women aged 70 to 74 years, continued screening resulted in a slightly reduced 8-year rate of breast cancer death: 2.7 deaths per 1,000 women, compared with 3.7 for those who stopped screening. (medscape.com)
  • The mean age of patients was 44.7 years. (bvsalud.org)
  • The age associated with breast cancer devel- range of the patients was 16-72 years. (who.int)
  • 1986 to 2005, with 20 years of many patients are treated in Algiers and Constantine. (who.int)
  • Most of the patients were aged 41-60 years, with an average level of education, retired, Catholic, white, married and in IIA staging. (bvsalud.org)
  • Patients were followed every monthly for 2 years, 2 monthly for 3rd year, 4 monthly for 4th year up to 5 year. (who.int)
  • Patients were assessed for Local recurrence up to 5 years. (who.int)
  • Data were obtained retrospectively from the Jordan Cancer Registry and hospital records. (who.int)
  • 2 Most primary care physicians have seen the physical and emotional impact that a diagnosis of breast cancer has on patients, their families, and their friends. (aafp.org)
  • Regarding CT examination of breast tissue, there are only a few reports on the possibility of its use for qualitative diagnosis of breast cancer. (scirp.org)
  • And the BC mortality rate also increased significantly and the average age of BC patients was quite early compared to western populace. (oncotarget.com)
  • Screening significantly contributed to the 23.5 percent decline in breast cancer mortality from 1990 to 2000. (aafp.org)
  • Patients with non-TNBC reported more intense present total pain, nausea and vomiting, better emotional functioning, lower cognitive functioning, use of significantly more prayer and hope, and more coping self-statements. (ons.org)
  • The results showed that at baseline the women in the patient sample experienced significantly higher levels of physical functioning and general health compared to the general population. (diva-portal.org)
  • Breast cancer (BC) is the second leading cause of cancer-related deaths amongst women in the United States, and morbidity and mortality of this disease increases each year ( 1 ). (frontiersin.org)
  • Approximately 1 in 8 women will be diagnosed with breast cancer during her lifetime, and within the US in 2013 there will be 232,340 newly diagnosed cases and 39,620 deaths associated with the disease [ 2 ]. (biomedcentral.com)
  • The majority of these deaths result from recurrent or metastatic disease, which occurs in 6% of newly diagnosed patients and approximately 30% of those previously diagnosed with an earlier stage [ 3 ]. (biomedcentral.com)
  • More than 20% of these deaths from non-communicable diseases are cancer-related deaths [ 1 ]. (karger.com)
  • BC has the highest incidence rate of all cancers in women worldwide (1.67 million) and accounts for over 500,000 deaths annually [ 2 ]. (karger.com)
  • Breast cancer (BC) makes up nearly 26% of malignant tumours worldwide and is the leading cause of cancer-related deaths in European women. (aaem.pl)
  • Cancer is one of the leading causes of female deaths worldwide. (jmir.org)
  • Cancer is responsible for about 20% of all deaths in industrialized countries and 10% in developing countries. (who.int)
  • It is estimated that around 43% of cancer deaths are due to tobacco use, unhealthy diets, alcohol consumption, inactive lifestyles and infection. (who.int)
  • Infectious agents are responsible for almost 25% of cancer deaths in the developing world and 6% in industrialized countries. (who.int)
  • In Brazil, in 2010, the number of deaths due to this cancer was 12,852 (12,705 females and 147 males) 2 and these mortality rates remain high in the country because the disease is still diagnosed in advanced stages. (bvsalud.org)
  • Many deaths, especially from bone cancer, have occurred in humans following long-term oral exposure to radium-226 and radium-228. (cdc.gov)
  • In this retrospective study, patients living within the Auckland region, diagnosed with ABC between the 1st January 2013 to the 31st December 2015 were identified from the Breast Cancer Registry. (hindawi.com)
  • Thus, tools to further stratify the risk of recurrence in patients with residual disease can optimize the utilization of available adjuvant therapy and improve the efficiency of clinical trials investigating novel agents in this setting. (nature.com)
  • It was hypothesised that three-dimensional ultrasonography (3-D US) could be used to preoperatively assess breast and tumour volume and show high association with histopathological measurements. (deepdyve.com)
  • 3-D US is an patient-friendly preoperative available technique to calculate both breast volume and tumour volume. (deepdyve.com)
  • Only 3 benign breast tumour tissues (12.5%) and none of the healthy breast tissue specimens were HPV-DNA-positive. (who.int)
  • The advantage of his model is that its parameters provide the information for clinicians and patients eagerly seek, such as the patient's chance of being cured, and if not cured, the time to death from the cancer. (scirp.org)
  • Benjamin also said breast cancer screening should be individualized based on a patient's personal risk of developing cancer. (abc15.com)
  • Partner with us to treat your patient's cancer. (mskcc.org)
  • She noted that the breast milk they analyzed had been frozen for more than a year before the patient's cancer diagnosis. (medscape.com)
  • Profile of human papillomavirus genotypes in breast and oesophageal cancer patients in Pretoria, South Africa. (bvsalud.org)
  • It is possible that use of appropriate HPV vaccines against genotypes responsible for these cancers may also prevent their development. (bvsalud.org)
  • Patient medical records were analysed, and DNA was extracted from their archived pathology material and amplified by polymerase chain reaction before hybridisation for HPV genotypes . (bvsalud.org)
  • The most prevalent HPV genotypes (>20% each) were HPV 16 , 70 and 51 for BC and HPV 51, 70, 16 and 82 for OSCC, with 31.7% and 60.0% of patients , respectively, having co-infection with ≥2 genotypes . (bvsalud.org)
  • In the breast cancer group, cocktail HPV genotypes were detected in 60 (46.5%) archived tissue blocks. (who.int)
  • 5 Two distinct types of multiple endocrine neoplasias are associated with the RET and MEN1 6 genes while VHL alterations result in kidney and other types of cancer. (nature.com)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • Many risk factors have been normal healthy breast tissues). (who.int)
  • The aim of the present study was to perform the accurate prognosis of different molecular types breast cancer (BC) by using the partitioning calculation method of the Ki‑67 index. (spandidos-publications.com)
  • On the whole, the present study demonstrates that the partitioning calculation of the Ki‑67 index can be used to judge the prognosis of patients with BC accurately. (spandidos-publications.com)
  • Given the modest numbers of Stage IIb patients (12 in each arm), and the retrospective nature of this study, further studies would benefit to clarify the role of PMRT in Stage IIb disease in young patients. (oncolink.org)
  • Safety was analysed in patients who received at least one dose of study medication. (nih.gov)
  • All patients had continuous enrollment for a 12-month baseline period prior to index and were followed until the end of the study window, disenrollment, or death, whichever came first. (biomedcentral.com)
  • The purpose of this study is to clarify the time-dependent effects between long-term oral contraceptive use and cancer risk. (aacrjournals.org)
  • Cumulative risk of cancer over the timespan of the study, as measured by the OR, and instantaneous risk, as measured by the HR, were assessed using Logistic and Cox regression analyses, respectively. (aacrjournals.org)
  • We performed a study to investigate the status of thyroid nodules and thyroid functions in Chinese breast cancer women. (oncotarget.com)
  • Results of this study have been published in this Breast Care [ 2 ] as well as others [ 3-5 ]. (karger.com)
  • These results are based on a study sample of n = 100 male breast cancer patients across Germany. (karger.com)
  • 1 ] as well as the N-MALE study regarding the patient perspective are in accordance: both studies report some experiences of stigmatization and of shortcomings including barriers in access to gynecological outpatient care and unclear responsibilities. (karger.com)
  • This study examines differences in objective cognitive function, activity levels and sleep in disease-free women who do and do not meet criteria for cancer-related fatigue syndrome (CRFS). (bmj.com)
  • One 2003 study found that in women who had breast cancer, massage therapy helped reduce not only anxiety and pain, but also the need for pain medication. (healthline.com)
  • Another study released around that time found that massage therapy and progressive muscle relaxation helped increase protective white blood cells in women with stage 1 and stage 2 breast cancer. (healthline.com)
  • 8 One study found that as many cancers were detected incidentally as were found by women trained to do routine breast self-examination. (aafp.org)
  • The aim of the study was to investigate the distribution of Candida species isolated from urine specimens of hospitalized patients in Akdeniz University Hospital, Antalya, Turkey, as well as their susceptibilities to antifungal agents. (who.int)
  • A total of 100 patients who had nosocomial candiduria between March 2003 and May 2004 at the facility were included in the study. (who.int)
  • In terms of methodology, Ana Vivancos, PhD, head of the VHIO Cancer Genomics Group and also one of the authors of the study, explained that they used two techniques to analyze the breast milk and blood samples: next-generation sequencing and droplet digital polymerase chain reaction. (medscape.com)
  • Ultrasonography , nuclear medicine study, and MRI have adjuvant roles in breast cancer imaging and staging. (medscape.com)
  • In patients of any age with increased breast density, which may mask small cancers, additional tests such as digital breast tomosynthesis (DBT), ultrasonography, nuclear medicine study, and MRI may be useful. (medscape.com)
  • A retrospective cross-sectional study of BC and OSCC patients managed at Steve Biko Academic Hospital from 2015 to 2019 was undertaken. (bvsalud.org)
  • a cross-sectional study was conducted in women with breast cancer. (bvsalud.org)
  • This study in Iraq used in situ hybridization to detect the frequency and genotyping of HPV in tissue specimens from 129 patients diagnosed with malignant breast cancer, 24 with benign breast tumours and 20 healthy controls. (who.int)
  • A total of 108 dyads including 108 breast cancer patients and 108 high-risk people (female family members) will be recruited to the study. (who.int)
  • To evaluate the effect of follow-up length on the outcome of breast cancer patients, we compared the 50- and 25-year follow-up results in terms of cure rate, overall mortality and mortalities from breast cancer, second cancer, and benign diseases. (scirp.org)
  • A review of the literature revealed that CML patients with this translocation tend to have an aggressive course and poor outcome. (who.int)
  • CRF adversely affects breast cancer patients in multiple aspects [ 9 ], which severely not only affects their quality of sleep but also prolongs their length of hospital stay and can result in a reduction of physical, mental, and emotional function and poor quality of life [ 10 ]. (springer.com)
  • 11 University Hospital Erlangen, Department of Obstetrics and Gynecology, Friedrich-Alexander-Universität Erlangen, Comprehensive Cancer Center Erlangen-Europäische Metropolregion Nuremberg, Erlangen, Germany. (nih.gov)
  • Since the registration of breast cancer started at the Kyoto University Hospital in 1953, the first author of the present paper (Y.Y.) assumed the responsibility to follow all patients who were surgically treated. (scirp.org)
  • If a patient was discharged, or hospitalized elsewhere, he made contact with the patient, her family members, her primary physician or the hospital staff. (scirp.org)
  • Once discharged from hospital, the patient is expected to continue doing this rehabilitation exercise program daily at home without supervision from a physiotherapist, a process referred to as "home rehabilitation. (jmir.org)
  • WALTHAM, Mass.--( BUSINESS WIRE )-- BostonGene today announced an agreement with Hokkaido University Hospital to drive the discovery, validation and implementation of a groundbreaking stratification protocol for HER2-positive breast cancer patients. (businesswire.com)
  • Affiliated with Hokkaido University School of Medicine, the hospital offers both high-quality patient care and cutting-edge medical research with an international perspective. (businesswire.com)
  • 2Iraqi National Cancer Research Centre, Baghdad of University, Baghdad, Iraq (Correspondence to N.A.S. Al-Alwan: [email protected]). (who.int)
  • RÉSUMÉ Le taux de survie à cinq ans chez les femmes atteintes d'un cancer du sein en Jordanie et certains des facteurs ayant eu une influence sur la survie ont été mesurés. (who.int)
  • Triple-negative breast cancer (TNBC) accounts for 15% of all breast cancers and is associated with higher rates of recurrence and death compared to non-triple-negative breast cancers 1 . (nature.com)
  • To determine differences in psychological distress, symptoms, coping capacity, and coping abilities among African American (AA) women with triple-negative breast cancer (TNBC) and non-TNBC and to explore differences in relationships among these variables. (ons.org)
  • Triple-negative breast cancer (TNBC) is a serious form of breast cancer that occurs more frequently in younger African American (AA) women (Susan G. Komen, 2012). (ons.org)
  • Background: Immunohistochemical (IHC) PD-L1 expression is commonly employed as predictive biomarker for checkpoint inhibitors in triple-negative breast cancer (TNBC). (lu.se)
  • Characteristics and results of breast cancer in elderly females treated with curative intent. (medigraphic.com)
  • Baseline patients' characteristics (N=366). (iiarjournals.org)
  • Chi-square test was conducted and showed no statistically significant relationship between the classification of BDI and the variables tested (characteristics related to patient and cancer-specific). (bvsalud.org)
  • Seventy-five of the 76 patients also had ultrasonography performed. (annals.edu.sg)
  • Ultrasonography showed solid masses in 73 patients and was negative in the other 2 patients. (annals.edu.sg)
  • At baseline (prior to the initiation of AI therapy among the breast cancer patients), 3 months, and 6 months, a comprehensive questionnaire was administered to participants that ascertained data on the experiencing of specific menopausal-type symptoms. (nih.gov)
  • Additionally, breast cancer patients were more likely than the women in the comparison group to report the new onset of many of these same symptoms during the follow-up time period. (nih.gov)
  • Approximately 20-33% of all cancer patients are treated with acid reducing agents (ARAs), most commonly proton pump inhibitors (PPIs), to reduce gastro esophageal reflux disease symptoms. (researchsquare.com)
  • The patients reported their symptoms daily. (jmir.org)
  • Psychological distress and burdensome symptoms in AA women with breast cancer have negative effects on emotional and cognitive functioning (Gaston-Johanssonet al. (ons.org)
  • When breast cancer has grown to the point where physical signs and symptoms appear, the patient feels a breast lump (usually painless). (medscape.com)
  • Because both RCB and ctDNA status are prognostic among patients with TNBC with residual disease, assessing the combined impact of both is of interest. (nature.com)
  • We detected ctDNA in 33% of TNBC patients with residual disease after NAST. (nature.com)
  • This overview of systematic reviews aims to critically appraise and consolidate evidence from current systematic reviews (SRs)/meta-analyses on the effects of exercise interventions on cancer-related fatigue (CRF) in breast cancer patients. (springer.com)
  • Landmark meta-analyses by the Early Breast Cancer Trialists' Collaborative Group (EBCTCG) initially showed a 20% to 25% relative risk reduction in breast cancer mortality for first-generation regimens (ie, cyclophosphamide/methotrexate/fluorouracil [CMF]) and increased benefit with the addition of anthracyclines and taxanes. (jnccn.org)
  • Whilst the introduction of the sentinel node biopsy has reduced the morbidity for pN0 patients dramatically the discussion regarding axillary dissection in nodal positive patients is currently ongoing. (biomedcentral.com)
  • Introduction: In India, almost 150,000 women are diagnosed with breast cancer every year and almost half of patients expected to die of the disease. (who.int)
  • Young age is considered an independent poor prognostic factor in patients with breast cancer. (oncolink.org)
  • Information on cancer diagnoses were collected from self-reported data and from national registers until March 2019. (aacrjournals.org)
  • In an attempt to solve this issue, we applied our recently developed algorithm, eTumorMetastasis, which constructs predictive models, on exome sequencing data to ER+ breast ( n = 755) cancer patients. (nature.com)
  • These data support the use of PMRT in young women with stage IIb-III breast cancer. (oncolink.org)
  • Thus, the data on the role of IL-33 in cancer progression was limited, and in particular, the function mediated by IL-33 in human BC is under-investigated. (frontiersin.org)
  • We interviewed 10 breast cancer survivors under the two main topics of "Rehabilitation" and "Technology" and performed a thematic analysis on the interview data. (jmir.org)
  • These data indicate that the incidence of thyroid disease in breast disease patients is higher than in normal population in China, and the breast diseases, especially breast cancer, might be related to the high incidence of thyroid nodules. (oncotarget.com)
  • Although the DL methods show promising improvements in breast cancer diagnosis, there are still issues of data scarcity and computational cost, which have been overcome to a significant extent by applying data augmentation and improved computational power of DL algorithms. (jmir.org)
  • We used a mixed-methods approach by triangulating qualitative interview data from n = 27 patients and standardized survey data from 100 patients. (karger.com)
  • Additional data are required to elucidate the best approach for identifying HER2-low patients likely to benefit from the novel therapy. (businesswire.com)
  • Approximately 300 patients are diagnosed with advanced breast cancer (ABC) in New Zealand (NZ) annually. (hindawi.com)
  • Breast cancer is reported to be the most frequent cancer type in women worldwide, with approximately 1.7 million newly diagnosed cases reported in 2012. (amrita.edu)