• trials
  • This inherent limitation of syntheses appears in the case of a meta-analysis of sodium-glucose cotransporter 2 inhibitors for the treatment of type 2 diabetes because many of the pertinent randomized trials did not handle patient dropout and "rescue" medication properly. (annals.org)
  • This manuscript describes two ongoing randomized clinical trials being conducted in two different health care systems, examining patient-based and provider-based interventions for managing hip and knee OA in primary care. (pubmedcentralcanada.ca)
  • The report is restricted to trials of treatments that can be administered by a patient in a non-clinical setting (i.e., at home or work). (nih.gov)
  • To be considered for this review, studies were required to be prospective, controlled trials of self-administered drug treatments aimed at the relief of symptoms of individual episodes of headache in patients with migraine. (nih.gov)
  • Following our selection criteria, we collected a total of 14 studies containing 16 randomized controlled trials (2620 patients) from a series of database about the treatment with vaptans for cirrhosis with ascites patients. (springer.com)
  • RTI International will lead the first randomized, controlled trials of a procedure that involves injecting an anesthetic into a nerve tissue center at the base of the neck to treat PTSD patients. (stripes.com)
  • Under the Declaration of Helsinki, patients in clinical trials must participate entirely voluntarily and must have the right to leave the trial at any time. (wikipedia.org)
  • This ethical imperative makes missing data an inevitable problem of clinical trials, and requires appropriate analysis methods to account for it. (wikipedia.org)
  • study
  • GEICAM/2012-07 is a study phase III, prospective, open, randomized, multicenter and national designed to assess patient preference for intravenous (IV) or subcutaneous (SC) of trastuzumab , and within the SC by the administration through the vial or device self-administration in patients with disseminated breast cancer HER2. (clinicaltrials.gov)
  • Since the randomization in the study until the start with subcutaneous trastuzumab , patients will receive a treatment cycle of intravenous trastuzumab as usual. (clinicaltrials.gov)
  • 6 In a naturalistic study using data from a large number of psychotherapy patients (n=4,761), 7 only four sessions were needed for 25% of the sample to improve. (scielo.br)
  • In another study, the trajectories of change of 10,854 patients with diverse diagnoses, treated in different settings by more than 513 therapists, were typified. (scielo.br)
  • This study included 47 patients with diabetes and 29 healthy individuals who underwent OCTA. (arvojournals.org)
  • In collaboration with researchers from Johns Hopkins University, Akonni conducted a retrospective study on 87 clinical isolates and 246 nasal swab samples acquired from a non-random, high‐risk patient population. (businesswire.com)
  • Randomization code will be revealed only after all patients completed the study. (clinicaltrials.gov)
  • AD patients (n = 421) were recruited from a clinical multi-centre study program in Sweden. (springer.com)
  • All patients received donepezil starting directly after study entry. (springer.com)
  • Data for the other patients were analysed until they dropped out (4 groups based on length in study). (springer.com)
  • Patients who remained longer in the study had better initial performance and a slower deterioration rate. (springer.com)
  • What distinguishes patients that actually complete a three-year study from those who drop out, for example in pattern of cognitive reduction, needs to be further investigated. (springer.com)
  • The three-year study will enroll 250 active-duty military patients from the Army hospitals who are diagnosed with PTSD. (stripes.com)
  • The study will include a qualitative component to gather impressions of the procedure from the patients, their families, behavioral therapists and psychiatrists. (stripes.com)
  • Some examples are as follows: Patients who do not satisfy the inclusion and/or exclusion criteria are included in the trial, A patient is randomized to Treatment A, but is treated with Treatment B, Some patients drop out from the study, or Some patients are not compliant, that is, do not take their medication as instructed, and so on. (wikipedia.org)
  • Methods to address missing data make assumptions about the relationship between dropout and study results in order to produce results which account for the missing data. (wikipedia.org)
  • Because the assumptions underlying a particular method may be inappropriate to a given study, care and expertise is required to address the issue. (wikipedia.org)
  • If a patient drops out of the study after the third week, then this value is "carried forward" and assumed to be his or her score for the 5 missing data points. (wikipedia.org)
  • The assumption is that the patients improve gradually from the start of the study until the end, so that carrying forward an intermediate value is a conservative estimate of how well the person would have done had he or she remained in the study. (wikipedia.org)
  • Blinding should be appropriate to the study, and is ideally double blind, wherein neither the patient nor doctor is aware of whether they are in the control or test group, eliminating any such psychological effects from the study. (wikipedia.org)
  • To receive the corresponding point, an article should describe the number of withdrawals and dropouts, in each of the study groups, and the underlying reasons. (wikipedia.org)
  • In early 2008, a noninferiority study versus vancomycin or metronidazole for Clostridium difficile associated diarrhea (CDAD) found that about half of the patients in the tolevamer group did not complete the treatment, versus 25% in the vancomycin and 29% in the metronidazole groups. (wikipedia.org)
  • The same paper, part of a study funded by the Bill & Melinda Gates Foundation, cited the impact of the Smart Sparrow platform on increasing enrollments and reducing dropouts. (wikipedia.org)
  • complications
  • Levodopa was introduced after it was demonstrated that main cause of PD is due to degeneration of dopaminergic neurons of the substantia nigra [ 4 , 5 ] and for the last several decades Levodopa prescription has been the standard therapy for PD patients although several complications have arisen since Levodopa can generate other motor complications as well [ 6 , 7 , 8 ]. (mdpi.com)
  • Obese patients are at increased risk of anaesthetic complications, and tracheal intubation can be more difficult. (biomedsearch.com)
  • fixed dose
  • Approximately 195 patients will be included to receive subcutaneous trastuzumab a fixed dose of 600 mg every 3 weeks for 4 cycles (2 administered from the injection of a vial with a syringe and 2 with the injection device). (clinicaltrials.gov)
  • data
  • He is also interested in developing methods to use shared data to confirm and extend published science, as well as to explore new hypotheses. (stanford.edu)
  • A medical telemetry system is provided for collecting the real-time physiologic data of patients (including ambulatory patients) of a medical facility, and for transferring the data via RF to a real-time data distribution network for monitoring and display. (google.com)
  • The system includes battery-powered remote telemeters which attach to respective patients, and which collect and transmit (in data packets) the physiologic data of the patients. (google.com)
  • The VCELLs, which are hardwire-connected to a LAN, forward the data packets received from the telemeters to patient monitoring stations on the LAN. (google.com)
  • Such data may provide hints as to the causal mechanisms and will have consequences for planning interventions for the individual patient, and for developing support systems for AD patients on the societal level. (springer.com)
  • One method of handling missing data is simply to impute, or fill in, values based on existing data. (wikipedia.org)
  • The LOCF method allows for the analysis of the data. (wikipedia.org)
  • psychotherapy
  • 11 Still, specific investigations into patterns of change in patients who drop out of psychotherapy are scarce. (scielo.br)
  • Psychotherapy is the use of psychological methods, particularly when based on regular personal interaction, to help a person change and overcome problems in desired ways. (wikipedia.org)
  • Influential editions of a work by psychiatrist Jerome Frank defined psychotherapy as a healing relationship using socially authorized methods in a series of contacts primarily involving words, acts and rituals-regarded as forms of persuasion and rhetoric. (wikipedia.org)
  • detection
  • Fluorescein angiography (FA) is an established method for observing fine details of retinal microvascular damage in DR. However, the measurement of this capillary dropout is not quantitative and spatial detection is also impossible since FA fails to detect a significant fraction of capillaries due to poor depth sectioning capacity and sensitivity to the angiogram quality. (arvojournals.org)
  • More specifically, the present invention relates to the detection of patient access disconnection, such as dislodgment of a patient access device during medical treatments or therapies including dialysis therapy. (google.com)
  • accurately
  • Of the 87 isolates, the TruArray test accurately classified 86 (98.8%) and correctly identified 14 mecA dropout specimens that were falsely positive in the BD GeneOhm MRSA or BD GeneOhm StaphSR tests. (businesswire.com)
  • treatments
  • In the emergency department, the patients will be assigned to either one of the two treatments using a computer-generated randomized numbers in a 1:1 ratio. (clinicaltrials.gov)
  • The present invention relates generally to patient access disconnection systems and methods for medical treatments. (google.com)
  • A variety of different medical treatments relate to the delivery of fluid to and/or from a patient, such as the delivery of blood between a patient and an extracorporeal system connected to the patient via a needle or needles or any suitable access device inserted within the patient. (google.com)
  • During these treatments, the patient is connected to an extracoporeal machine, and the patient's blood is pumped through the machine. (google.com)
  • Also, the per-protocol restricts the comparison of the treatments to the ideal patients, that is, those who adhered perfectly to the clinical trial instructions as stipulated in the protocol. (wikipedia.org)
  • although
  • Procedures performed on sex cells before fertilization may instead be referred to as methods of oocyte selection or sperm selection, although the methods and aims partly overlap with PGD. (wikipedia.org)
  • Results
  • However, it is also important that none of those involved in a clinical trial, whether the researcher, the subject patient or any other involved parties, should allow their own prior expectations to affect reporting of results. (wikipedia.org)
  • wherein
  • 4 . The remote telemeter according to claim 1 , wherein the control program implements a switch-over protocol in which the remote telemeter establishes wireless links to selected receivers of the plurality of receivers in response to movement of the patient throughout the medical facility. (google.com)
  • 4. The extracorporeal blood system of claim 1 , wherein the controller is configured to assume Z P approaches infinity upon dislodgment of the access device from the patient, such that Z becomes at least substantially equal to Z D . (google.com)
  • behavioral
  • The 12-month, telephone-based patient intervention focuses on physical activity, weight management, and cognitive behavioral pain management. (pubmedcentralcanada.ca)
  • The sample included 63 patients (23 dropouts and 40 completers) from a controlled clinical trial, which compared narrative therapy vs. cognitive-behavioral therapy for major depressive disorder. (scielo.br)
  • initially
  • As an aid we constructed three algorithms corresponding to the cognitive domains, which can be used to characterize patients initially, identify rapid decliners and follow the course of the disease. (springer.com)
  • and Sabina Spielrein, initially a patient of Jung and later a physician and one of the first female psychoanalysts. (wikipedia.org)
  • time
  • After a defined time period, the patients in the test group are assessed for health improvements in comparison with the control group. (wikipedia.org)
  • These categories are numbered 0 to 4, and based on whether or not the patient has tinnitus with hearing loss, tinnitus with no hearing loss, tinnitus with hearing loss and hyperacusis, and tinnitus with hearing loss and hyperacusis for an extended amount of time. (wikipedia.org)
  • The concept has been applied to numerous aspects of public life, including accessibility of polling stations, care provided to HIV patients, whether men and women have equal opportunities to travel on a spaceship, bilingual education, skin color of models in Brazil, television time for political candidates, army promotions, admittance to universities, and ethnicity in the United States. (wikipedia.org)
  • 2002
  • The screenplay was adapted by writer Christopher Hampton from his 2002 stage play The Talking Cure, which was based on the 1993 non-fiction book by John Kerr, A Most Dangerous Method: The story of Jung, Freud, and Sabina Spielrein. (wikipedia.org)
  • involves
  • The provider intervention involves provision of patient-specific recommendations for care (e.g., referral to physical therapy, knee brace, joint injection), based on evidence-based guidelines. (pubmedcentralcanada.ca)
  • 2NaCN + O2 → 2 NaOCN One of the more recent methods of synthesis involves modifying a procedure in the production of fatty alcohols. (wikipedia.org)
  • period
  • In addition, they set up a method of quarantine for Grand Rapids that would keep any outbreaks from spreading and required a 35-day period of isolation for infected patients. (wikipedia.org)
  • relationship
  • After his attempt to confine their relationship again to doctor and patient, she appeals to Freud for his professional help, and forces Jung to tell Freud the truth about their relationship, reminding him that she could have publicly damaged him but did not want to. (wikipedia.org)
  • meta-analysis
  • At Hopkins, he taught courses on Systematic reviews and Meta-analysis, Diagnostic and prognostic testing, and several courses on epidemiologic, clinical research and inferential methods. (stanford.edu)
  • cell
  • Single cell sequencing was selected as the method of the year 2013 by Nature Publishing Group. (wikipedia.org)
  • One popular method used for single cell genome sequencing is multiple displacement amplification and this enables research into various areas such as microbial genetics, ecology and infectious diseases. (wikipedia.org)
  • therapies
  • It is only in last few decades that some breakthrough in development of specific therapies has been made to treat PD patients since the first patient was diagnosed with Parkinsonian syndrome [ 1 ]. (mdpi.com)
  • However, some recommended therapies are under-utilized in clinical settings, and the majority of patients with hip and knee OA are overweight and physically inactive. (pubmedcentralcanada.ca)
  • disease
  • The drug is contraindicated in patients with obstructive bowel disease and in newborn children with reduced gut motility. (wikipedia.org)
  • When used to screen for a specific genetic disease, its main advantage is that it avoids selective pregnancy termination as the method makes it highly likely that the baby will be free of the disease under consideration. (wikipedia.org)
  • different
  • The VCELLs are distributed throughout the medical facility such that different VCELLs provide coverage for different patient areas. (google.com)
  • This was conducted by setting up a large network of medical professionals and neighborhood organizations in order to obtain large samples of pertussis from as many different patients as possible. (wikipedia.org)
  • families
  • She soon learns that much of this new science is founded on the doctors' observations of themselves, each other, and their families, not just their patients. (wikipedia.org)
  • medical
  • Steven Goodman, MD, MHS, PhD is Associate Dean of Clinical and Translational Research and Professor of Medicine and of Health Research & Policy, directing Stanford's CTSA/Spectrum training programs in medical research methods and serving as chief of the Division of Epidemiology in HRP. (stanford.edu)
  • The architecture can accommodate a large number of patients (e.g., 500 or more) while operating within the transmission power limits of the VHF medical telemetry band. (google.com)
  • particularly
  • He also has worked on the connections between ethics and scientific methods, particularly in the domain of interventional research, and policy making. (stanford.edu)