• fixed dose
  • Approximately 195 patients will be included to receive subcutaneous trastuzumab a fixed dose of 600 mg every 3 weeks for 4 cycles (2 administered from the injection of a vial with a syringe and 2 with the injection device). (clinicaltrials.gov)
  • wherein
  • 4 . The remote telemeter according to claim 1 , wherein the control program implements a switch-over protocol in which the remote telemeter establishes wireless links to selected receivers of the plurality of receivers in response to movement of the patient throughout the medical facility. (google.com)
  • 4. The extracorporeal blood system of claim 1 , wherein the controller is configured to assume Z P approaches infinity upon dislodgment of the access device from the patient, such that Z becomes at least substantially equal to Z D . (google.com)
  • 6. The apparatus of claim 5 wherein the control device is attached to the patient. (patentgenius.com)
  • Blinding should be appropriate to the study, and is ideally double blind, wherein neither the patient nor doctor is aware of whether they are in the control or test group, eliminating any such psychological effects from the study. (wikipedia.org)
  • complications
  • Levodopa was introduced after it was demonstrated that main cause of PD is due to degeneration of dopaminergic neurons of the substantia nigra [ 4 , 5 ] and for the last several decades Levodopa prescription has been the standard therapy for PD patients although several complications have arisen since Levodopa can generate other motor complications as well [ 6 , 7 , 8 ]. (mdpi.com)
  • Obese patients are at increased risk of anaesthetic complications, and tracheal intubation can be more difficult. (biomedsearch.com)
  • study
  • GEICAM/2012-07 is a study phase III, prospective, open, randomized, multicenter and national designed to assess patient preference for intravenous (IV) or subcutaneous (SC) of trastuzumab , and within the SC by the administration through the vial or device self-administration in patients with disseminated breast cancer HER2. (clinicaltrials.gov)
  • Since the randomization in the study until the start with subcutaneous trastuzumab , patients will receive a treatment cycle of intravenous trastuzumab as usual. (clinicaltrials.gov)
  • In collaboration with researchers from Johns Hopkins University, Akonni conducted a retrospective study on 87 clinical isolates and 246 nasal swab samples acquired from a non-random, high‐risk patient population. (businesswire.com)
  • Randomization code will be revealed only after all patients completed the study. (clinicaltrials.gov)
  • AD patients (n = 421) were recruited from a clinical multi-centre study program in Sweden. (springer.com)
  • All patients received donepezil starting directly after study entry. (springer.com)
  • Data for the other patients were analysed until they dropped out (4 groups based on length in study). (springer.com)
  • Patients who remained longer in the study had better initial performance and a slower deterioration rate. (springer.com)
  • What distinguishes patients that actually complete a three-year study from those who drop out, for example in pattern of cognitive reduction, needs to be further investigated. (springer.com)
  • Methods The study was a randomised single-blind sham-controlled clinical trial. (bmj.com)
  • Some examples are as follows: Patients who do not satisfy the inclusion and/or exclusion criteria are included in the trial, A patient is randomized to Treatment A, but is treated with Treatment B, Some patients drop out from the study, or Some patients are not compliant, that is, do not take their medication as instructed, and so on. (wikipedia.org)
  • Methods to address missing data make assumptions about the relationship between dropout and study results in order to produce results which account for the missing data. (wikipedia.org)
  • Because the assumptions underlying a particular method may be inappropriate to a given study, care and expertise is required to address the issue. (wikipedia.org)
  • If a patient drops out of the study after the third week, then this value is "carried forward" and assumed to be his or her score for the 5 missing data points. (wikipedia.org)
  • The assumption is that the patients improve gradually from the start of the study until the end, so that carrying forward an intermediate value is a conservative estimate of how well the person would have done had he or she remained in the study. (wikipedia.org)
  • To receive the corresponding point, an article should describe the number of withdrawals and dropouts, in each of the study groups, and the underlying reasons. (wikipedia.org)
  • In early 2008, a noninferiority study versus vancomycin or metronidazole for Clostridium difficile associated diarrhea (CDAD) found that about half of the patients in the tolevamer group did not complete the treatment, versus 25% in the vancomycin and 29% in the metronidazole groups. (wikipedia.org)
  • The same paper, part of a study funded by the Bill & Melinda Gates Foundation, cited the impact of the Smart Sparrow platform on increasing enrollments and reducing dropouts. (wikipedia.org)
  • data
  • He is also interested in developing methods to use shared data to confirm and extend published science, as well as to explore new hypotheses. (stanford.edu)
  • He is Vice-chair of the Methodology Committee of the Patient Centered Outcomes Research Institute (PCORI), where he leads their open science and data sharing efforts, and is scientific advisor for the national Blue Cross-Blue Shield Technology Assessment Program. (stanford.edu)
  • A medical telemetry system is provided for collecting the real-time physiologic data of patients (including ambulatory patients) of a medical facility, and for transferring the data via RF to a real-time data distribution network for monitoring and display. (google.com)
  • The system includes battery-powered remote telemeters which attach to respective patients, and which collect and transmit (in data packets) the physiologic data of the patients. (google.com)
  • The VCELLs, which are hardwire-connected to a LAN, forward the data packets received from the telemeters to patient monitoring stations on the LAN. (google.com)
  • This data suggests that OAG patients with DM may have more retinal capillary dropout associated with their disease compared to OAG patients without DM. (arvojournals.org)
  • In Latin America, substance related disorders are highly prevalent and one of the treatment strategies is the Therapeutic Communities (TCs), however, in Latin America there is scarce data about this treatment strategies, their quality, drop-out rates and patient satisfaction. (readbyqxmd.com)
  • Such data may provide hints as to the causal mechanisms and will have consequences for planning interventions for the individual patient, and for developing support systems for AD patients on the societal level. (springer.com)
  • Since patients often drop out because they find a treatment doesn't seem to be working for them or because it causes harmful side effects, missing data is often correlated with the treatment's efficacy or safety. (wikipedia.org)
  • One method of handling missing data is simply to impute, or fill in, values based on existing data. (wikipedia.org)
  • The LOCF method allows for the analysis of the data. (wikipedia.org)
  • variants
  • For example, several PCR-based tests have difficulty detecting deletion variants such as the methicillin-resistant Staphylococcus aureus (MRSA) mecA dropout strains. (businesswire.com)
  • Determine the effects of variants in 11 genes on dropout rate and dose in patients receiving methadone or buprenorphine/naloxone (ClinicalTrials.gov Identifier: NCT00315341). (readbyqxmd.com)
  • time
  • After a defined time period, the patients in the test group are assessed for health improvements in comparison with the control group. (wikipedia.org)
  • These categories are numbered 0 to 4, and based on whether or not the patient has tinnitus with hearing loss, tinnitus with no hearing loss, tinnitus with hearing loss and hyperacusis, and tinnitus with hearing loss and hyperacusis for an extended amount of time. (wikipedia.org)
  • The concept has been applied to numerous aspects of public life, including accessibility of polling stations, care provided to HIV patients, whether men and women have equal opportunities to travel on a spaceship, bilingual education, skin color of models in Brazil, television time for political candidates, army promotions, admittance to universities, and ethnicity in the United States. (wikipedia.org)
  • involves
  • The provider intervention involves provision of patient-specific recommendations for care (e.g., referral to physical therapy, knee brace, joint injection), based on evidence-based guidelines. (pubmedcentralcanada.ca)
  • 2NaCN + O2 → 2 NaOCN One of the more recent methods of synthesis involves modifying a procedure in the production of fatty alcohols. (wikipedia.org)
  • receive
  • Protocol violations" may occur, such as when the patients do not receive the full intervention or the correct intervention or a few ineligible patients are randomly allocated in error. (wikipedia.org)
  • often
  • Increasing the strength of the cannabis taken and an increasing use of more effective methods of delivery often increase the progression of cannabis dependency. (wikipedia.org)
  • needle
  • An apparatus for detecting dislodgement of a needle inserted into a patient includes a sensor for detecting wetness due to blood and a sensor holder to secure the sensor to the patient such that the sensor detects wetness due to blood loss from the patient upon dislodgement of the needle. (patentgenius.com)
  • relationship
  • Influential editions of a work by psychiatrist Jerome Frank defined psychotherapy as a healing relationship using socially authorized methods in a series of contacts primarily involving words, acts and rituals-regarded as forms of persuasion and rhetoric. (wikipedia.org)
  • cell
  • Single cell sequencing was selected as the method of the year 2013 by Nature Publishing Group. (wikipedia.org)
  • One popular method used for single cell genome sequencing is multiple displacement amplification and this enables research into various areas such as microbial genetics, ecology and infectious diseases. (wikipedia.org)
  • Results
  • However, it is also important that none of those involved in a clinical trial, whether the researcher, the subject patient or any other involved parties, should allow their own prior expectations to affect reporting of results. (wikipedia.org)
  • cognitive
  • The 12-month, telephone-based patient intervention focuses on physical activity, weight management, and cognitive behavioral pain management. (pubmedcentralcanada.ca)
  • As an aid we constructed three algorithms corresponding to the cognitive domains, which can be used to characterize patients initially, identify rapid decliners and follow the course of the disease. (springer.com)
  • therapies
  • It is only in last few decades that some breakthrough in development of specific therapies has been made to treat PD patients since the first patient was diagnosed with Parkinsonian syndrome [ 1 ]. (mdpi.com)
  • However, some recommended therapies are under-utilized in clinical settings, and the majority of patients with hip and knee OA are overweight and physically inactive. (pubmedcentralcanada.ca)
  • disease
  • The drug is contraindicated in patients with obstructive bowel disease and in newborn children with reduced gut motility. (wikipedia.org)
  • When used to screen for a specific genetic disease, its main advantage is that it avoids selective pregnancy termination as the method makes it highly likely that the baby will be free of the disease under consideration. (wikipedia.org)
  • weight
  • Treatment for childhood obesity is characterised by patient non-attendance and drop-out, and widespread failure to achieve weight maintenance. (bmj.com)
  • We studied 56 obese patients before weight loss surgery who were divided into two groups: morbid obesity and super obesity. (biomedsearch.com)
  • medical
  • Steven Goodman, MD, MHS, PhD is Associate Dean of Clinical and Translational Research and Professor of Medicine and of Health Research & Policy, directing Stanford's CTSA/Spectrum training programs in medical research methods and serving as chief of the Division of Epidemiology in HRP. (stanford.edu)
  • The VCELLs are distributed throughout the medical facility such that different VCELLs provide coverage for different patient areas. (google.com)
  • The architecture can accommodate a large number of patients (e.g., 500 or more) while operating within the transmission power limits of the VHF medical telemetry band. (google.com)
  • This was conducted by setting up a large network of medical professionals and neighborhood organizations in order to obtain large samples of pertussis from as many different patients as possible. (wikipedia.org)
  • particularly
  • He also has worked on the connections between ethics and scientific methods, particularly in the domain of interventional research, and policy making. (stanford.edu)
  • blood
  • In patients without DM, the change in the number of superior zero blood flow pixels was not statistically significant (p=0.13), leading to a statistically significant difference between the two groups (p=0.0164). (arvojournals.org)
  • a controller configured to model a total impedance Z according to at least two lumped impedances including (i) a lumped impedance Z D due to components of the extracorporeal blood machine and (ii) a lumped impedance Z P due to access of the extracorporeal blood circuit to the patient. (google.com)
  • although
  • Procedures performed on sex cells before fertilization may instead be referred to as methods of oocyte selection or sperm selection, although the methods and aims partly overlap with PGD. (wikipedia.org)
  • system
  • The patient is taught the basic knowledge about the auditory system and its function, the mechanism of tinnitus generation and the annoyance associated with tinnitus. (wikipedia.org)
  • They continued working on refining their inoculation methods through 1938, when they instituted a three vaccine system that involved less of the inactivated bacteria, but was found to be much more effective at providing resistance to infection. (wikipedia.org)
  • several
  • At Hopkins, he taught courses on Systematic reviews and Meta-analysis, Diagnostic and prognostic testing, and several courses on epidemiologic, clinical research and inferential methods. (stanford.edu)
  • The material is prepared by sulfonation of polystyrene: (CH2CHC6H5)n + n SO3 → (CH2CHC6H4SO3H)n Several methods exist for this conversion, which can lead to varying degree of sulfonation. (wikipedia.org)
  • systems
  • This application claims priority to and the benefit as a continuation application of U.S. patent application "ACCESS DISCONNECTION SYSTEMS AND METHODS," Ser. (google.com)
  • shows
  • However, recent research shows that this method gives a biased estimate of the treatment effect and underestimates the variability of the estimated result. (wikipedia.org)
  • make
  • While the methods developed had allowed Kendrick and Eldering to make specific vaccines for those infected, they didn't begin work on a general vaccine until late 1933. (wikipedia.org)
  • addition
  • In addition, they set up a method of quarantine for Grand Rapids that would keep any outbreaks from spreading and required a 35-day period of isolation for infected patients. (wikipedia.org)
  • population
  • However, by restricting the analysis to a selected patient population, it does not show the practical value of the new drug. (wikipedia.org)
  • response
  • Asopressin V2 receptor antagonists could play an effective and safe role in symptomatic treatment for cirrhosis patients with ascites, especially for refractory ascites patients who presented insufficient response to conventional diuretics. (springer.com)