PneumoniaInfectionsRhinovirusHMPVInfluenza virusSymptomsDiseasesIllnessesIllnessBronchitisHospitalizationEpidemiologyPathogensDetectionCoronavirusCoughSeverity of bronchiolitisChildrenSevere respiratoryCommonlyChild with bronchiolitisContact with respiratory secretionsDiseaseDistressAirwayInfection among infantsSecretionsLungExacerbationsAsthmaCOVID-19 Pandemic20202016ParamyxoviridaeInducesAirwaysCommon
Pneumonia10
- RSV (and possibly hMPV) infection is suspected in infants and young children with bronchiolitis or pneumonia during RSV season. (msdmanuals.com)
- However, in vulnerable populations, such as newborns, infants, the elderly and immune-compromised individuals, these opportunistic pathogens can also affect the lower respiratory tract, causing a more severe disease (e.g., pneumonia). (mdpi.com)
- Clinical symptoms of HMPV infection may progress to bronchiolitis or pneumonia and are similar to other viruses that cause upper and lower respiratory infections. (blogspot.com)
- Those with any pneumonia were significantly less likely to have a respiratory virus identified in their nasopharynges and had significantly higher C reactive protein (CRP) values than those in the viral infection and asthma groups. (bmj.com)
- Respiratory viruses and Mycoplasma pneumoniae are commonly detected in children with non-severe pneumonia. (bmj.com)
- Dr John Kelley, from western Massachusetts, said his practice was seeing a lot of children coming in with pneumonia or suffering from a combination of RSV and other respiratory illnesses. (dailymail.co.uk)
- In the United States, RSV is estimated to be responsible for 73,400 to 126,300 hospitalizations annually for bronchiolitis and pneumonia alone among children younger than one year. (quidel.com)
- nd or 3rd The main cause of lower respiratory tract viral infections and viral pneumonia Chan added that the number of children in need of medical care is also increasing. (exbulletin.com)
- croup , bronchiolitis (such as respiratory syncytial virus), pneumonia, asthma Exacerbation . (exbulletin.com)
- Human metapneumovirus (hMPV) is a major cause of acute respiratory infections ranging from wheezing to bronchiolitis and pneumonia in children worldwide. (biomedcentral.com)
Infections28
- However, most infections are due to respiratory syncytial virus (RSV) ( 2 ). (cdc.gov)
- Human metapneumovirus infections in young and elderly adults. (medscape.com)
- Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups. (medscape.com)
- Human metapneumovirus infections cause similar symptoms and clinical severity as respiratory syncytial virus infections. (medscape.com)
- Respiratory syncytial virus and human metapneumovirus infections cause seasonal lower respiratory tract disease, particularly in infants and young children. (msdmanuals.com)
- Her research is focused on the investigation of viral- and host-specific mechanisms that contribute to the pathogenesis of respiratory viral infections. (utmb.edu)
- Acute respiratory tract infections are one of the most common diseases in adults and children in the world, which is facing a heavy burden on the health system and society. (pharmcourse.com)
- A similar trend was found in China, in a study of pediatric patients with viral respiratory tract infections in Shanghai. (pharmcourse.com)
- A downward trend in the prevalence of respiratory viruses, including influenza, parainfluenza virus, adenovirus, coronaviruses (excluding SARS-CoV-2), human metapneumovirus, rhinovirus, and respiratory syncytial virus infections, was also observed in other national studies. (pharmcourse.com)
- Epidemiologists believe that several factors played a role in this trend: the high virulence of SARS-CoV-2, which provided a powerful surge of coronavirus infection and its prevalence in the picture of viral respiratory infections, and the widespread use of preventive hygiene measures, as well as the massive introduction of quarantine, which further allowed to control the transmission of other respiratory viruses. (pharmcourse.com)
- This study, conducted by scientists at the University of Bristol in collaboration with pharmaceutical giant Pfizer, was the first to compare hospital admissions for respiratory infections caused by SARS-CoV-2 and other respiratory infections. (pharmcourse.com)
- Using data from 135014 hospitalizations from two large hospitals in Bristol between August 2020 and November 2021, the researchers found that 12557 hospitalizations were associated with acute lower respiratory illness in patients presenting with symptoms of respiratory infections (including cough, fever) or radiological evidence of pathology. (pharmcourse.com)
- Anticipating new epidemiological season, let's talk about transmission routes, clinical symptoms and treatment tactics for respiratory viral infections not associated with SARS-CoV-2. (pharmcourse.com)
- Understanding the pathophysiology of common pediatric respiratory infections requires an appreciation for the normal anatomy and physiology of the pediatric respiratory system. (ceufast.com)
- Viral infections are important causes of asthma exacerbations in children, and lower respiratory tract infections (LRTIs), caused by viruses such as respiratory syncytial virus (RSV) and rhinovirus (RV), are a leading cause of bronchiolitis in infants. (atsjournals.org)
- The incubation period is estimated to be 3 to 6 days, and the median duration of illness can vary depending upon severity but is similar to other respiratory infections caused by viruses. (blogspot.com)
- Proper coding for respiratory infections in infants and children is in the details. (aapc.com)
- Double or triple infections with HRV-C and respiratory syncytial virus and/or bocavirus were diagnosed in 33.3% of the HRV-infected patients, but no correlation with severity of clinical outcome was observed. (plos.org)
- Objectives To describe critically ill children with respiratory infections, classify them by infection syndrome type and determine the prevalence of Mycoplasma pneumoniae detection. (bmj.com)
- There are many other viruses that infect the respiratory tract and there is a large overlap of symptoms among these infections. (quidel.com)
- In May, the CDC reported a spike in human metapneumovirus (hMPV) infections. (exbulletin.com)
- During a given respiratory virus season (October to April), hMPV typically accounts for 5-10% of symptomatic respiratory virus infections, but this is even higher during peak hMPV seasons. (exbulletin.com)
- To test the speculation that viral lung illnesses brought about by respiratory syncytial infection or flu infection are part of the way because of overproduction of TNF, we utilized enemy of TNF neutralizer to treat mice with lung sickness brought about by these infections. (alliedacademies.org)
- Human respiratory syncytial virus (RSV) is a ubiquitous virus of worldwide distribution and is the leading cause of infant morbidity from respiratory infections. (intechopen.com)
- Adenovirus Infections Infection with one of the many adenoviruses may be asymptomatic or result in specific syndromes, including mild respiratory infections, keratoconjunctivitis, gastroenteritis, cystitis, and primary. (merckmanuals.com)
- Overview of Enterovirus Infections Enteroviruses, along with rhinoviruses (see Common Cold) and human parechoviruses, are a genus of picornaviruses ( pico , or small, RNA viruses). (merckmanuals.com)
- Co-infections between viruses and bacteria were the most common (~69%), followed by viral-viral (~23%) and bacterial-bacterial (~7%) co-infections. (healthtrackrx.com)
- Respiratory tract infections (RTIs) are one of the major public health concerns across the world. (healthtrackrx.com)
Rhinovirus4
- Acute bronchiolitis is usually the result of infection by respiratory syncytial virus (72% of cases) or human rhinovirus (26% of cases). (wikipedia.org)
- Adenovirus (AdV) and other viruses as Respiratory Syncytial Virus (RSV), Meta-pneumovirus (MPV), Rhinovirus (RV) and Para-influenza Virus (PIV) have been detected in the respiratory tract of children with acute bronchiolitis and recurrent wheezing. (atlasofscience.org)
- Moreover, the RT-LAMP assay showed good specificity and no cross-reactivity was observed with human rhinovirus (HRV), human respiratory syncytial Virus (RSV), or influenza virus A/PR/8/34 (H1N1). (biomedcentral.com)
- A 2020 review indicates that rhinovirus (RV), the virus that causes the common cold, can create an inflammatory environment and affect specific risk genes in people predisposed to developing asthma. (medicalnewstoday.com)
HMPV25
- Thus, the new virus was termed human metapneumovirus (hMPV). (cdc.gov)
- No specific FDA approved antiviral therapy is currently available for human metapneumovirus (hMPV) infection. (medscape.com)
- hMPV is a similar but separate virus. (msdmanuals.com)
- Coinfection with human metapneumovirus (hMPV) and other viral respiratory pathogens has been documented in several studies, with the clinical significance in these situations unclear. (medscape.com)
- Dr. Casola's research efforts include investigating the pathogenesis of respiratory diseases caused by human metapneumovirus (hMPV), using molecular virology and animal model approaches, to investigate hMPV-induced lung disease and test novel antivirals and therapeutic agents. (utmb.edu)
- Human metapneumovirus (HMPV) -a recently identified virus-can cause respiratory disease, especially in young children. (blogspot.com)
- Healthcare professionals should consider HMPV , along with flu and respiratory syncytial virus (RSV), as a potential diagnosis when they see patients with respiratory illness, especially during late winter and early spring. (blogspot.com)
- Human metapneumovirus (HMPV) can cause upper and lower respiratory disease in people of all ages, especially among young children, older adults, and people with weakened immune systems. (blogspot.com)
- HMPV was discovered in 2001 and is in the paramyxovirus family along with measles and respiratory syncytial virus (RSV). (blogspot.com)
- Broader use of molecular diagnostic testing has increased identification and awareness of HMPV as an important cause of upper and lower respiratory infection. (blogspot.com)
- Surveillance data from CDC's the National Respiratory and Enteric Virus Surveillance System (NREVSS) shows HMPV to be most active during late winter or early spring in temperate climates. (blogspot.com)
- HMPV, RSV, and influenza can circulate simultaneously during the respiratory virus season. (blogspot.com)
- There are steps that can be taken to help prevent the spread of HMPV and other respiratory viruses. (blogspot.com)
- Since HMPV is a recently recognized respiratory virus, healthcare professionals may not routinely consider or test for HMPV. (blogspot.com)
- Human metapneumovirus (hMPV), a member of the family Paramyxoviridae, is an important cause of acute respiratory tract disease. (eur.nl)
- Six days after challenge FI-hMPV-primed monkeys had developed eosinophilic bronchitis and bronchiolitis, indicative of a hypersensitivity response. (eur.nl)
- According to last week's news release, CDC increasing cases of human metapneumovirus, also known as hMPV. (exbulletin.com)
- Dele Ogunseitan The University of California, Irvine - Professor of Public Health Program, Population Health and Disease Prevention, Ph.D., told Healthline that hMPV causes lower respiratory tract information and only RSV is more common. (exbulletin.com)
- The majority of patients with acute hMPV infection are children and present with the most common upper respiratory tract symptoms. (exbulletin.com)
- Patients generally cannot tell the difference between the common cold virus and hMPV, but laboratory tests may be able to distinguish and identify the specific virus involved, Ogunseitan explained. (exbulletin.com)
- In this study, visual RT-LAMP assay for hMPV was performed in one step with the addition of hydroxynaphthol blue (HNB), and were used to detect respiratory samples. (biomedcentral.com)
- hMPV is a negative-sense, single-stranded RNA virus belonging to the genus Metapneumovirus in the subfamily Pneumovirinae of the family Paramyxoviridae . (biomedcentral.com)
- Currently, the most common hMPV detection methods are by virus isolation, enzyme-linked immunoassays, McAb immuno-fluorescent assays and molecular biology methods based on the polymerase chain reaction (PCR, RT-PCR, nested PCR, and real-time PCR). (biomedcentral.com)
- Additionally, RNA can be amplified by reverse transcription coupled with LAMP (RT-LAMP) in one step, making it suitable to detect RNA viruses such as hMPV. (biomedcentral.com)
- While respiratory viruses such as influenza A/B, respiratory syncytial virus (RSV), human metapneumovirus (hMPV), rhinoviruses (HRV), etc. dominate the RTIs, 10-15% of patients develop secondary bacterial coinfection [ 2 ]. (healthtrackrx.com)
Influenza virus2
- Cytokine profiles in the respiratory tract during primary infection with human metapneumovirus, respiratory syncytial virus, or influenza virus in infants. (medscape.com)
- Traditionally, laboratories used viral culture to detect influenza virus and improvements in virus culture techniques allowed for results within 48-72 hours. (quidel.com)
Symptoms12
- Schildgen O, Geikowski T, Glatzel T, Schuster J, Simon A. Frequency of human metapneumovirus in the upper respiratory tract of children with symptoms of an acute otitis media. (medscape.com)
- Respiratory syncytial virus (RSV) is a very common virus that leads to mild, cold-like symptoms in adults and older healthy children. (medlineplus.gov)
- Bronchiolitis typically presents in children under two years old and is characterized by a constellation of respiratory symptoms that consists of fever, rhinorrhea, cough, wheeze, tachypnea and increased work of breathing such as nasal flaring or grunting that develops over one to three days. (wikipedia.org)
- These illnesses typically begin with upper respiratory symptoms and fever, then progress over several days to dyspnea, cough, wheezing, and/or crackles on chest auscultation. (msdmanuals.com)
- Read on for more information about bronchiolitis, its causes, signs and symptoms, how to treat it and how to prevent it. (healthychildren.org)
- What are the signs and -symptoms of bronchiolitis? (healthychildren.org)
- We introduce this common virus and explore the symptoms, diagnosis, treatment and prevention of its potentially life-threatening illness. (pediacast.org)
- Differentiate between the signs and symptoms of common pediatric respiratory illnesses. (ceufast.com)
- Infants with bronchiolitis who develop symptoms severe enough to warrant hospitalization are at increased risk of developing recurrent wheezing or childhood asthma ( 1 - 6 ). (atsjournals.org)
- RSV is a very common virus infection that often resembles the common cold with mild symptoms such as a runny nose, coughing and low-grade fever. (quidel.com)
- Bronchitis in adults .Bronchiolitis and exacerbations of asthma are likely to be accompanied by respiratory symptoms Wheezing Perhaps even in children with no previous history of wheezing, Chan explained. (exbulletin.com)
- Croup is usually preceded by upper respiratory infection symptoms. (merckmanuals.com)
Diseases6
- Dr. Casola is a physician-scientist specialized in pediatric infectious diseases, with research expertise in the area of respiratory viral pathogens, lung inflammation, and cellular signaling. (utmb.edu)
- All cause mortality data were examined as well as deaths classified by primary cause to respiratory diseases (chapter VIII, International Classification of Disease 9th revision). (bmj.com)
- Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. (mdpi.com)
- American Academy of Pediatrics Committee on Infectious Diseases, American Academy of Pediatrics Bronchiolitis Guidelines Committee. (medscape.com)
- open-access medical journal of scientific papers covering laboratory research data on human infectious diseases as well as its application for elucidation and management of epidemic processes. (ncipd.org)
- Around 70% of instances of viral bronchiolitis are expected to Respiratory Syncytial Infection (RSV) diseases. (alliedacademies.org)
Illnesses10
- Antibiotics are not helpful because they treat illnesses caused by bacteria, not viruses. (healthychildren.org)
- 92% of participants will be able to identify common pediatric respiratory illnesses. (ceufast.com)
- Describe pediatric respiratory anatomy, physiology, and pathophysiology of pediatric respiratory illnesses. (ceufast.com)
- Identify methods of definitive diagnosis for common pediatric respiratory illnesses. (ceufast.com)
- Describe clinical care and interventions for pediatric respiratory illnesses. (ceufast.com)
- Explain infection prevention methods for common pediatric respiratory illnesses. (ceufast.com)
- Respiratory illnesses are a significant cause of sickness and healthcare utilization in children. (ceufast.com)
- Healthcare providers must have the knowledge and skills to accurately assess and differentiate between various respiratory illnesses to provide timely intervention and treatment. (ceufast.com)
- It is also not known whether viral bronchiolitis (both inpatient and outpatient illnesses) contributes to asthma inception or simply identifies infants who are at increased risk for subsequent wheezing ( 2 , 7 - 10 ). (atsjournals.org)
- Many viruses that infect humans and cause similar respiratory illnesses are cold With most parts of the world in hibernation (lockdown) for the past two years and many of these viruses not circulating in the population, the number of cases could spike in recent months," Ogunseitan said. (exbulletin.com)
Illness6
- Bronchiolitis is an important cause of illness and death in infants. (cdc.gov)
- Children are at an increased risk for progression to severe respiratory disease if they have any of the following additional factors: Preterm infant (gestational age less than 37 weeks) Younger age at onset of illness (less than 3 months of age) Congenital heart disease Immunodeficiency Chronic lung disease Neurological disorders Tobacco smoke exposure Wheezing Wheezing heard in the lungs of an adult using a stethoscope. (wikipedia.org)
- Bronchiolitis may cause more severe illness in -children who have a chronic illness. (healthychildren.org)
- Clinicians must provide patients and caregivers with comprehensive and clear education regarding treating and preventing the respiratory illness. (ceufast.com)
- Stockton J, Stephenson I, Fleming D, Zambon M. Human Metapneumovirus as a cause of community-acquired respiratory illness . (blogspot.com)
- As the virus culture was used for the detection of major respiratory viruses, the isolated virus could be the main causative agent of respiratory illness. (datexis.com)
Bronchitis12
- What is the difference between bronchiolitis and bronchitis? (healthychildren.org)
- Bronchiolitis is not the same as bronchitis, which is an infection of the larger, more central airways that typically causes problems in adults. (healthychildren.org)
- What is Acute Bronchiolitis/Bronchitis? (kidsclinic.sg)
- Acute bronchiolitis or bronchitis is an infection of the lower airways leading to the lungs. (kidsclinic.sg)
- Both conditions are similar, except that the term bronchiolitis is generally used for children one year old and below, while the term bronchitis is generally used for children one year old and above. (kidsclinic.sg)
- Prolonged episodes of bronchiolitis/bronchitis can also be complicated by secondary bacterial infection (e.g. (kidsclinic.sg)
- Pollutants (e.g. second hand smoke or haze) can worsen bronchiolitis/bronchitis and must be avoided. (kidsclinic.sg)
- Does My Child have Bronchiolitis/Bronchitis? (kidsclinic.sg)
- What are the Treatment Options for a Child with Bronchiolitis/Bronchitis? (kidsclinic.sg)
- Your paediatrician will personalise the treatment according to the severity and the cause of the bronchiolitis/bronchitis (most likely cause is usually germs). (kidsclinic.sg)
- How do I Care for a Child with Bronchiolitis/Bronchitis? (kidsclinic.sg)
- For those with recurrent bronchiolitis/bronchitis or recurrent wheeze, especially when there is a family history of asthma/bronchitis, there may be a component of hyper-reactive airways and this group of children may require a longer period airway stabilisers (e.g. (kidsclinic.sg)
Hospitalization5
- Updated guidance for palivizumab prophylaxis among infants and young children at increased risk of hospitalization for respiratory syncytial virus infection. (medscape.com)
- Palivizumab Prophylaxis in Infants and Young Children at Increased Risk of Hospitalization for Respiratory Syncytial Virus Infection. (medscape.com)
- To date, studies addressing the incidence of asthma after bronchiolitis severe enough to warrant hospitalization have focused almost exclusively on RSV, but a number of recent studies suggest that other respiratory pathogens, including RV, may contribute as well. (atsjournals.org)
- Lower respiratory tract disease is rarely severe enough to require hospitalization or intensive care. (exbulletin.com)
- Viral bronchiolitis is the commonest single reason for juvenile hospitalization in the Western World. (alliedacademies.org)
Epidemiology2
- Defining the Epidemiology and Burden of Severe Respiratory Syncytial Virus Infection Among Infants and Children in Western Countries. (medscape.com)
- Few comprehensive data exist regarding the epidemiology of severe acute respiratory infec- tions (SARI) in low income countries. (123dok.net)
Pathogens3
- Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? (mdpi.com)
- Over the ensuing decades the cotton rat has been shown to be a preferred model of an impressive list of human pathogens: RSV, influenza (A and B serotypes), adenoviruses (several serotypes), parainfluenza virus (type 3), measles, herpes simplex (types 1 and 2), human metapneumovirus, Staphylococcus species, Streptococcus species, and Mycobacterium tuberculosis. (sigmovir.com)
- The permissiveness of a single, small laboratory animal for such a wide array of human pathogens is unprecedented. (sigmovir.com)
Detection8
- As part of a larger study examining the immunopathogenesis of severe bronchiolitis, nonbronchoscopic bronchoalveolar lavage samples were collected from 30 infants ventilated with RSV bronchiolitis (determined by antigen detection in nasopharyngeal aspirates) in 2000 and 2001. (cdc.gov)
- Detection of the human metapneumovirus genome was performed by reverse transcription-polymerase chain amplification (RT-PCR) of the matrix (M), fusion (F), and nucleoprotein (N) genes. (cdc.gov)
- Suzuki A, Watanabe O, Okamoto M, Endo H, Yano H, Suetake M. Detection of human metapneumovirus from children with acute otitis media. (medscape.com)
- The direct fluorescent antibody (DFA) method allows detection of virus within 2-3 hours, but is labor intensive and requires considerable experience. (quidel.com)
- molecular diagnostic methods were used for the detection of other respiratory viruses in the other studies whereas we used virus culturing. (datexis.com)
- These findings are consistent with a Norwegian study that reported detection of HBoV alone and a high-viral-load were associated with respiratory tract infection. (datexis.com)
- In a study performed in Hong Kong, a higher detection rate of HBoV was observed in NPAs positive for common respiratory viruses than in those that were negative for the same. (datexis.com)
- However, in our study, similar detection rate of HBoV was observed in the samples positive and negative for other respiratory viruses in the R-mix culture (Data are not shown). (datexis.com)
Coronavirus1
- 2021) Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Infection on Pregnancy Outcomes: A Population-based Study. (vircell.com)
Cough1
- Bronchiolitis often starts with signs of a cold , such as a runny nose, mild cough and fever . (healthychildren.org)
Severity of bronchiolitis2
- Such coinfection might be a factor influencing the severity of bronchiolitis. (cdc.gov)
- Thus, many possible determinants exist that may contribute to the severity of bronchiolitis and the subsequent development of asthma. (atsjournals.org)
Children25
- Subsequently, human metapneumovirus has been detected in children in Australia ( 5 ) and Canada ( 6 ). (cdc.gov)
- Metapneumovirus and acute wheezing in children. (medscape.com)
- A newly discovered human pneumovirus isolated from young children with respiratory tract disease. (medscape.com)
- Children who have had RSV bronchiolitis may be more likely to develop asthma. (medlineplus.gov)
- Acute bronchiolitis is due to a viral infection usually affecting children younger than two years of age. (wikipedia.org)
- About 10% to 30% of children under the age of two years are affected by bronchiolitis at some point in time. (wikipedia.org)
- However, a laboratory diagnosis may facilitate hospital infection control by allowing segregation of children infected with the same virus. (msdmanuals.com)
- Some children with bronchiolitis need to be treated in a hospital for breathing problems or dehydration. (healthychildren.org)
- To quantify mortality attributable to influenza and respiratory syncytial virus (RSV) infection in children. (bmj.com)
- 7 Respiratory syncytial virus (RSV) is also recognised as a cause of excess winter mortality particularly in young children and the elderly population. (bmj.com)
- When children breathe, air enters the body through the upper respiratory tract and the nose and travels down the lower respiratory tract from the larynx and the trachea to the lungs through the main-stem bronchi to the right lung and the left lung. (ceufast.com)
- Burden of human metapneumovirus infection in young children. (blogspot.com)
- Purpose : This study was design and performed for evaluations of resent clinical pattern of bronchiolitis caused by RSV infection with children under 2 year of age for 5 years, who were admitted to pediatric ward. (e-cep.org)
- Methods : The inclusion criteria of the patients were children under 24 month-of-age, clinical manifestations of lower respiratory tract infection, and RSV antigen that. (e-cep.org)
- Human rhinoviruses (HRVs) are a highly prevalent cause of acute respiratory infection in children. (plos.org)
- Given the increased interest for novel HRV strain identification and their worldwide distribution, we have carried out clinical and molecular diagnosis of HRV strains in a 2-year study of children with acute respiratory infection visiting one district hospital in Shanghai. (plos.org)
- Sixty-four HRV-infected outpatients were diagnosed amongst 827 children with acute low respiratory tract infection. (plos.org)
- All children aged 2 months-18 years with presumed respiratory infection who were admitted to a tertiary hospital paediatric intensive care unit (PICU) between September 2015 and October 2016 were eligible. (bmj.com)
- Attention to antibiotic treatment and rapid diagnostic testing for Mycoplasma in older, critically ill children should be considered to optimise management and avert morbidity and mortality from respiratory infection. (bmj.com)
- There are clear biochemical (eg, C reactive protein) and microbiological (eg, respiratory virus prevalence) differences between critically ill children with different respiratory infection syndromes. (bmj.com)
- Respiratory syncytial virus (RSV) is a very common cause of respiratory tract infection especially in young children. (quidel.com)
- Bronchiolitis is more likely to occur in preschool children and younger. (exbulletin.com)
- Nearly 100% of children in the USA are infected with the virus by 2 to 3 years of age, several hundred infants may die directly from the infection, while the deaths of an additional several thousand may be attributed to RSV-related complications ( Nair et al, 2010 ). (intechopen.com)
- Younger children may develop bronchiolitis , which is a viral infection that may lead to childhood asthma . (medicalnewstoday.com)
- Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis, a viral lung infection common in young children and a major risk factor for developing childhood asthma. (medicalnewstoday.com)
Severe respiratory1
- Reverse transcription-polymerase chain reaction was used to detect segments of the M (matrix), N (nucleoprotein), and F (fusion) genes of human metapneumovirus in bronchoalveolar fluid from 30 infants with severe respiratory syncytial virus bronchiolitis. (cdc.gov)
Commonly1
- This is most commonly caused by respiratory syncytial virus (RSV, also known as human pneumovirus). (wikipedia.org)
Child with bronchiolitis1
- Similar sounds might be heard in a child with bronchiolitis. (wikipedia.org)
Contact with respiratory secretions2
- Use eye/face protection if aerosol-generating procedure performed or contact with respiratory secretions anticipated. (cdc.gov)
- RSV is readily spread from contact with respiratory secretions from infected individuals or contaminated surfaces and objects. (quidel.com)
Disease11
- Chronic bronchiolitis is the general term used for small airways disease in adults, notably in chronic obstructive pulmonary disease. (wikipedia.org)
- Velayutham TS, Kolli D, Ivancicuc T, Garofalo R.P. and Casola A. Critical role of TLR4 in human metapneumovirus mediated innate immune responses and disease pathogenesis. (utmb.edu)
- Human listeriosis is a serious foodborne disease caused by Listeria monocytogenes, a bacterium often called Listeria. (atlasofscience.org)
- Health departments can contact CDC for assistance with laboratory diagnostics or consultation through the CDC Unexplained Respiratory Disease Outbreaks work group. (blogspot.com)
- In the 1960s, vaccination with formalin-inactivated paramyxovirus preparations - respiratory syncytial virus (RSV) and measles virus (MV) - resulted in predisposition for enhanced disease upon natural infection. (eur.nl)
- The cotton rat is considered the model of choice for Respiratory Syncytial Virus (RSV) studies because it recapitulates several characteristic features in the human disease. (sigmovir.com)
- Experts at the Centers for Disease Control and Prevention have warned that cases of the little-known virus have spiked this winter and spring. (exbulletin.com)
- Albeit most kids with essential RSV contaminations escape with onlymild upper respiratory side effects, bronchiolitis is in many cases extreme or deadly in youngsters with ongoing lung sickness of outset, a background marked by rashness or intrinsic heart disease.In expansion, youngsters hospitalized with bronchiolitis are bound to experience repetitive wheezing during youth, and to be analyzed as asthmatic [ 1 ]. (alliedacademies.org)
- As of late, it has been demonstrated the way that authorized detached neutralizer treatment can postpone lower respiratory disease. (alliedacademies.org)
- Interest has subsequently centered on new medicines that could ease the seriousness of disease in youngsters with bronchiolitis [ 2 ]. (alliedacademies.org)
- The incubation period of RSV respiratory disease is estimated to be three to five days (Black, 2003). (intechopen.com)
Distress5
- 24 months and is characterized by respiratory distress, wheezing, and/or crackles. (msdmanuals.com)
- Respiratory viruses can also exacerbate asthma and lead to various types of respiratory distress syndromes. (mdpi.com)
- When an RSV infection becomes more serious and progresses to bronchiolitis, patient management goals are to relieve respiratory distress, alleviate airway obstruction and improve oxygen levels. (quidel.com)
- The child may awaken at night with respiratory distress, tachypnea, and retractions. (merckmanuals.com)
- The obvious respiratory distress and harsh inspiratory stridor are the most dramatic physical findings. (merckmanuals.com)
Airway5
- Over the past several years, she has identified several inducible intracellular signaling pathways activated by respiratory syncytial virus (RSV) in airway epithelial cells with particular emphasis on the role of reactive oxygen species in RSV induced lung inflammation both in vitro and in vivo, using a mouse model of RSV infection. (utmb.edu)
- Antioxidant mimetics modulate oxidative stress and cellular signaling in airway epithelial cells infected with respiratory syncytial virus. (utmb.edu)
- Human Metapneumovirus Glycoprotein G Disrupts Mitochondrial Signaling in Airway Epithelial Cells. (utmb.edu)
- In infants who have died of RSV bronchiolitis, histologic study of lung tissue demonstrates mononuclear cell and neutrophil infiltration of the peribronchiolar areas, necrosis of the small airway epithelium, plugging of the lumens with exudate and edema, and atelectasis and hyperinflation. (medscape.com)
- Bronchiolitis causes airway obstruction, breathing difficulties , and wheezing . (medicalnewstoday.com)
Infection among infants1
- Bronchiolitis is a common respiratory infection among infants. (healthychildren.org)
Secretions1
- Secretions can be analyzed for virus in the laboratory by means of culture, antigen-revealing techniques, or polymerase chain reaction (PCR). (medscape.com)
Lung2
- It is not known whether viral bronchiolitis directly contributes to asthma causation or simply identifies infants at risk for subsequent wheezing, as from an atopic predisposition or preexisting abnormal lung function. (atsjournals.org)
- Lung immunopathology triggered by a specific virus is much less severe when tumour inflammatory response is inhibited. (alliedacademies.org)
Exacerbations3
- Relevance of human metapneumovirus in exacerbations of COPD. (medscape.com)
- Respiratory viral infection in exacerbations of COPD. (medscape.com)
- Evidence indicates that RV, the common cold virus, is the most common single trigger of viral exacerbations. (medicalnewstoday.com)
Asthma9
- Perez-Yarza EG, Moreno A, Lazaro P, Mejias A, Ramilo O. The association between respiratory syncytial virus infection and the development of childhood asthma: a systematic review of the literature. (medscape.com)
- Infants hospitalized with bronchiolitis are at significantly increased risk for both recurrent wheezing and childhood asthma. (atsjournals.org)
- One such determinant is the potential involvement of genetic susceptibility loci to asthma after viral bronchiolitis, a critical area that is just beginning to be evaluated. (atsjournals.org)
- By clarifying the roles of both host- (genetic) and virus- (environment) specific factors that contribute to the frequency and severity of viral LRTI, it may be possible to determine if severe LRTIs cause asthma, or if asthma susceptibility predisposes patients to severe LRTI in response to viral infection. (atsjournals.org)
- Viral-induced asthma, or viral asthma, occurs when a virus triggers an asthma attack . (medicalnewstoday.com)
- Doctors may need to differentiate between bronchiolitis and asthma. (medicalnewstoday.com)
- Can a virus cause asthma? (medicalnewstoday.com)
- The 2020 review adds that breathing difficulty induced by either of these viruses may have associations with the later development of asthma. (medicalnewstoday.com)
- The virus for the common cold can be a primary trigger for viral asthma. (medicalnewstoday.com)
COVID-19 Pandemic2
- Changes in influenza and other respiratory virus activity during the COVID-19 pandemic-United States, 2020-2021. (msdmanuals.com)
- strong>SARS-CoV-2, the virus responsible for COVID-19 pandemic, has posed huge global health challenges. (ncipd.org)
20201
- 2020) Results of a Zika virus screening programme in asymptomatic pregnant women in Spain. (vircell.com)
20161
- 2016) Zika virus infection in pregnant women in Barcelona, Spain. (vircell.com)
Paramyxoviridae2
- In June 2001, Osterhaus and colleagues reported the discovery of a "new" human respiratory virus ( Pneumovirinae subfamily, Paramyxoviridae family) ( 3 ). (cdc.gov)
- RSV is a member of the Paramyxoviridae family of viruses. (quidel.com)
Induces1
- Respiratory syncytial virus induces oxidative stress by modulating antioxidant enzymes. (utmb.edu)
Airways2
- Bronchiolitis is inflammation of the small airways in the lungs. (wikipedia.org)
- Much of the pathology caused by RSV is related to damage of the lining of the small airways of the respiratory tract. (quidel.com)
Common1
- Differential production of inflammatory cytokines in primary infection with human metapneumovirus and with other common respiratory viruses of infancy. (medscape.com)