Maternal growth and development fetal development. Medical search. Frequent questions

Therefore, we investigated the effect of maternal (i.e. gestation and lactation) n-3 PUFA deficiency on microglial function and its consequences on hippocampal development. (nature.com)
The fetal origins hypothesis states that fetal undernutrition in middle to late gestation, which leads to disproportionate fetal growth, programmes later coronary heart disease. (bmj.com)
The hypothesis states that coronary heart disease is associated with specific patterns of disproportionate fetal growth that result from fetal undernutrition in middle to late gestation. (bmj.com)
Maternal nano-titanium dioxide (nano -TiO2) inhalation exposure during gestation results in decreased fetal female mass, maternal estrogen production, and placental mass. (cdc.gov)
Additionally, the impacts of toxicant exposure can occur in a sexually dimorphic manner, which has been shown after maternal diesel exhaust exposure during gestation. (cdc.gov)
Therefore, we hypothesized that maternal nano-TiO2 inhalation exposure during gestation alters placental function in a sexually dimorphic manner. (cdc.gov)
These results demonstrate that maternal nano-TiO2 inhalation exposure during gestation has greater impacts on fetal females and their placental units. (cdc.gov)
At day 17 of gestation, LPD- and Emb-LPD-fed conceptuses displayed smaller placentas and larger fetuses respectively, resulting in increased fetal:placental ratios in both groups compared with NPD conceptuses. (manchester.ac.uk)
Maternal plasma concentrations of placental growth factor (PlGF), soluble fms-like tyrosine kinase 1 (sFlt-1), and soluble endoglin (sEng) were available at 26 weeks of gestation in 540 women with type 1 diabetes enrolled in the Diabetes and Preeclampsia Intervention Trial. (diabetesjournals.org)
We demonstrated that tolcapone in early gestation caused abortion and delayed fetus development in a dose-dependent manner. (biorxiv.org)
Taking tolcapone in mid-gestation barely caused embryo lethality, however, the mice developed preeclampsia-like phenotypes, including maternal hypertension, proteinuria and fetal growth restriction. (biorxiv.org)
In conclusion, tolcapone causes embryo lethality and growth restriction in early gestation, while in mid-gestation tolcapone causes preeclampsia-like phenotypes in mice with defective trophoblast invasion. (biorxiv.org)
Administration of tolcapone in animal gestation has been implicated in fetal growth restriction and malformation, however, the studies are rather limited and the pathogenesis is unknown 10 . (biorxiv.org)
However, providing good nutrition to pregnant cattle during late gestation supports rapid fetal growth, calf health and performance. (unl.edu)

In this webinar, the distinguished speaker will discuss the impacts of maternal obesity on placental function and offspring outcomes, and discuss ways we may be able to intervene and improve placental lipid metabolism with changes to maternal diet during pregnancy. (tufts.edu)
First is the recognition of the importance of male health in pregnancy outcomes and fetal health," he said. (neurosciencenews.com)
This study examines whether supplementation of betaine, a choline derivative, has positive effects on fetal metabolic outcomes in mouse progeny exposed to maternal obesity and GDM. (cuny.edu)
We propose a temporal-specific mechanism by which maternal BS influences fetal growth and lipid metabolic outcomes of HF mice during prenatal development. (cuny.edu)
In twin pregnancy, proper maternal weight gain during pregnancy is associated with pregnancy-related complications and neonatal outcomes, as in singleton pregnancy (10-12). (researchsquare.com)
We aims to determine the maternal PFBS exposure and the maternal and fetal outcomes and the underlining mechanisms. (duke.edu)
The study complements our previous work that identified fetal head growth trajectories associated with different developmental, behavioural, visual and growth outcomes at 2 years of age. (ox.ac.uk)
The paper complements work published by the same groups in 2021 that identified fetal head growth trajectories that are associated with different developmental, behavioural, visual and growth outcomes at 2 years of age. (ox.ac.uk)
Parity and maternal age have been shown to increase the risk of adverse neonatal outcomes, such as intra-uterine growth restriction (IUGR), low birth weight (LBW) and mortality. (bvsalud.org)

Our pilot epidemiology study showed a positive association between PFBS exposure and risk of PIH which is the leading cause of maternal and fetal morbidity and mortality. (duke.edu)
It affects 3%-7% of all pregnancies [ 10 ] and is a major cause of maternal and fetal mortality. (hindawi.com)

Fetal growth restriction (FGR) refers to a condition in which a fetus is unable to achieve its genetically determined potential size. (medscape.com)
Both heterogeneity and tissue specialization of immune cells may hold the key to understanding the pathophysiology of some important pregnancy complications, such as miscarriage and fetal growth restriction (FGR), which is defined as the failure of the fetus to achieve its genetically determined growth potential. (elifesciences.org)
We measured the height, pre-pregnant body weight, and maternal body weight of women with twin pregnancies and evaluated the relationship between the maternal weight gain at each trimester and fetal growth restriction according to pre-pregnancy body mass index. (researchsquare.com)
Moreover, unlike in singleton pregnancies, twin pregnancy mothers have a higher likelihood of weight gain and pregnancy-related complications, such as fetal growth restriction, preeclampsia, or gestational diabetes (3, 4). (researchsquare.com)
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice. (bvsalud.org)

FGR causes a spectrum of perinatal complications, including fetal morbidity and mortality, iatrogenic prematurity, fetal compromise in labor, need for induction of labor, and cesarean delivery. (medscape.com)

Maternal exposure to secondhand smoke during pregnancy causes small reductions in birth weight and research suggests it may cause preterm delivery. (cdc.gov)
Evaluation of causative factors for intrinsic disorders leading to poor growth may include a fetal karyotype, maternal serology for infectious processes, and an environmental exposure history. (medscape.com)
Using multidisciplinary approaches, we reveal that maternal exposure to an n-3 PUFA deficient diet impairs offspring's microglial homeostatic signature and phagocytic activity, underpinning excessive synaptic pruning and subsequent behavioral abnormalities. (nature.com)
Sexually dimorphic modifications in placental cyclooxygeanse metabolites after maternal nanomaterial inhalation exposure. (cdc.gov)
CONCLUSION: This study finds support for fetal origins of endometriosis, in that exposure to adverse environment or restricted development during the perinatal period may increase the risk. (lu.se)
Researchers report paternal alcohol exposure prior to conception is associated with an increased risk of fetal alcohol syndrome (FAS) and facial growth defects in their offspring. (neurosciencenews.com)
Research investigating fetal alcohol syndrome (FAS) exclusively examines maternal alcohol exposure. (neurosciencenews.com)
Exposure to high blood pressure in the womb increases the risk for impaired fetal growth and the risk for cardiovascular disease in adult life. (nih.gov)
Such exposure has been linked to a number of adverse health conditions including cancer and abnormal reproductive development (USEPA, 2014). (duke.edu)
In addition, a recent study showed that exposure of pregnant mice to PFBS causes hypothyroxinemia and abnormal development of female offspring. (duke.edu)
Thus, maternal exposure of PFSB could affect short- and long-term health of both mothers and babies. (duke.edu)
The proposed study is uniquely positioned to answer critical public health questions about how perinatal exposure of PFBS impacts maternal and fetal health conditions. (duke.edu)
Maternal lipopolysaccharide (LPS) exposure during pregnancy has been related to IUGR. (bvsalud.org)
Here, we explored whether paternal LPS exposure before mating impaired fetal development . (bvsalud.org)
Interestingly, fetal weight and crown-rump length were reduced, while the incidence of IUGR was increased in paternal LPS exposure group. (bvsalud.org)
Additionally, paternal LPS exposure leaded to poor placental development through causing cell proliferation inhibition and apoptosis . (bvsalud.org)
Overall, our results provide evidence that paternal LPS exposure causes poor placental development and subsequently IUGR may be via down-regulating MEST/PI3K/AKT pathway, and then inducing cell proliferation inhibition and apoptosis in placentas . (bvsalud.org)

These disorders are thought to occur as a result of the alteration of normal fetal physiology in utero. (medscape.com)
Unfortunately, bovine antibodies cannot pass the placental barrier and are not transferred from the cow to the foetal calf in utero. (sfi.ie)

Optimal oxygen supply to fetus is maintained by increase in mother's hemoglobin concentration, preference of blood flow through placenta compared to myometrium, musculature of the uterus and remarkably high oxygen affinity of fetal blood. (childhealth-explanation.com)
The placenta is not capable of making these essential fatty acids either, and so the fetus relies on maternal supply and placental transfer of these critical nutrients for development. (tufts.edu)
Workalemahu T, Ouidir M, Shrestha D, Wu J, Grantz KL, and Tekola-Ayele F. Differential DNA methylation in placenta associated with maternal blood pressure during pregnancy. (nih.gov)
At E12.5, BS prevented fetal and placental overgrowth and downregulated glucose and fatty acid transporters (Glut1 and Fatp1) and the growth-promoting insulin-like growth factor 2 (Igf2) and its receptor Igf1r in the placenta of HF, glucose-intolerant dams (P (cuny.edu)
Appropriate fetal growth, regulated by maternal nutrition and nutrient transport across the placenta, is a critical factor for adult offspring long-term health. (manchester.ac.uk)
These fetal growth patterns are also associated with blood flow and nutrient transfer by the placenta, demonstrating a complex interaction between maternal and fetal nutrition early in pregnancy that influences postnatal weight and eventually adult health. (ox.ac.uk)
In order to prevent rejection of the fetus, the placenta expresses an intricate pattern of major histocompatibility complex molecules, immunizing the mother against the foreign fetal tissue [ 3 ]. (hindawi.com)
Treatment for PE is symptomatic, and removal of the placenta is the only curative treatment, suggesting that the placenta is a key in the development of PE. (hindawi.com)

Does maternal obesity impact fetal brain development? (news-medical.net)
In a new study, researchers assessed the impact of maternal obesity on brain development in the fetus. (news-medical.net)
Additionally, the impact the maternal obesity during pregnancy, and the effects this has on offspring long-term health and development, is also an emerging area of our research interest. (edu.au)
Maternal obesity increases the risk of gestational diabetes mellitus (GDM), which results in fetal overgrowth and long-lasting metabolic dysfunctioning in the offspring. (cuny.edu)
Animal and human epidemiological studies have established that sub-optimal maternal diet throughout pregnancy results in offspring that are at increased risk of later metabolic disease including diabetes and obesity. (nottingham.ac.uk)

Of all fetuses at or below the 10th percentile for growth, only approximately 40% are at high risk for potentially preventable perinatal death (see image below). (medscape.com)
José Villar , Professor of Perinatal Medicine at the University of Oxford, who co-led the study said: 'This is the first comprehensive evidence, across geographic populations, of the complex interaction between maternal and fetal metabolism that regulates, early in pregnancy, unique fetal trajectories linked specifically to weight, adiposity and development during childhood. (ox.ac.uk)
El hipotiroidismo no tratado se relaciona con riesgo aumentado de parto pretérmino, mortalidad perinatal, bajo peso al nacer y alteraciones en el desarrollo neuropsicomotor del neonato. (bvsalud.org)
Untreated hypothyroidism is associated with an increased risk of preterm delivery, perinatal mortality, low birth weight, and alterations in the neuropsychomotor development of the neonate. (bvsalud.org)

Objective of the study: The study was aimed at investigating the effects of maternal age and parity on the birth weight of newborns from singleton pregnancies and term deliveries. (bvsalud.org)

SGA is defined as growth at the 10th or less percentile for weight of all fetuses at that gestational age. (medscape.com)
We also found that an estimated 26% of the association between maternal smoking and early-onset endometriosis could be explained by birthweight-for-gestational age. (lu.se)
In addition to helping regulate growth hormones, blood sugar and cholesterol, a protein-rich diet may help prevent the development of gestational diabetes. (whattoexpect.com)
However, determining the correlation between maternal weight gain and gestational age of pregnancy was difficult, as it focused on the total weight gain during the entire pregnancy period. (researchsquare.com)
The large for gestational age at birth association was also partially attenuated by maternal glucose concentrations. (biomedcentral.com)
We recently reported associations between fetal imprinted genes represented as an allele score and both gestational diabetes and maternal glucose concentrations in late pregnancy [ 6 ]. (biomedcentral.com)

Indeed, maternal ILC2s promote fetal growth and protect against fetal mortality upon systemic endotoxin challenge. (elifesciences.org)
WHO has helped to organize the global conference Tracking progress in child survival: countdown to 2015 (London, 13 and 14 December 2005), the first in a two- year cycle of rolling reviews to assess progress towards reducing child mortality and improving maternal health. (who.int)
FPT is a passive immunity dysfunction that predisposes calves to development of disease and increases the risk of calf mortality. (sfi.ie)

This study's aim was to estimate the prevalence and maternal age and other risk factors of miscarriage among Sudanese women. (bvsalud.org)
Unlike the global age-associated risk of miscarriage, the risk of miscarriage among Sudanese women follows a unique curve in relation to maternal age. (bvsalud.org)

With limited nutritional reserve, the fetus redistributes blood flow to sustain function and to help in the development of vital organs. (medscape.com)
They reflect adaptations that the fetus made to sustain its development-adaptations that may be permanent. (bmj.com)
SUMMARY Different nutritional disorders prevail at different stages in the life cycle, e.g. growth retardation in the fetus, protein energy deficiency in children, noncommunicable conditions in adults. (who.int)
We propose, however, that genetically determined insulin resistance results in impaired insulin-mediated growth in the fetus as well as insulin resistance in adult life. (nih.gov)
Lipids are critical for proper fetal development, but the fetus is unable to synthesize the critical long chain polyunsaturated fatty acids at the rate required to fulfill its developmental requirements. (tufts.edu)
The pregnancy category C means animal studies showed risk to fetus and studies on humans are unavailable, while potential benefits in maternal disease control may outweigh the potential risks to fetus. (biorxiv.org)
The fetal origins hypothesis proposes that the fetus adapts its growth rate as a response to changes in nutrient and oxygen supply. (bmj.com)
However, in all species it has the same fundamental function, to nourish the growing fetus, by establishing contact with the maternal blood circulation [ 1 ]. (hindawi.com)

4, 6 The association between poor lung function and cardiovascular disease may therefore be partly related to intrauterine factors that affect fetal growth, programme cardiovascular disease, and also affect lung growth and development. (bmj.com)

Las hormonas tiroideas desempeñan un papel fundamental en el desarrollo del embarazo y el crecimiento fetal. (bvsalud.org)

Novant Health Maternal-Fetal Medicine - Matthews offers advanced obstetric care for patients with high-risk pregnancies due to preexisting health conditions, high-order multiple pregnancies and pregnancies in which fetal anomalies have been detected. (novanthealth.org)
Furthermore, weight gain in the second trimester of pregnancy is considered a powerful indicator of fetal growth, especially in normal weight pregnancies. (researchsquare.com)
The incidence of twin pregnancies has been increasing due to advanced maternal age and the development of assisted reproductive techniques (ARTs) (1, 2). (researchsquare.com)
It is believed that glucose-stimulated fetal insulin secretion stimulates growth whether or not pregnancies are affected by diabetes [ 4 ]. (biomedcentral.com)

Implementation science for maternal health equity. (wayne.edu)
The Hertfordshire records were maintained by health visitors and include measurements of growth in infancy as well as birth weight. (bmj.com)
Nonetheless, the past biennium has witnessed a clear increase in global attention for maternal and child health, including adolescent health. (who.int)
WHO and concerned partners launched the Partnership for Maternal, Newborn and Child Health in September 2005, to facilitate rapid acceleration of programme implementation through improved partner coordination and coherence. (who.int)
Supporting maternal and newborn health. (who.int)
The Secretariat is preparing a policy and planning framework for policy-makers that aims to improve newborn health through a continuum of care between maternal and child health services. (who.int)
Workshops for programme managers on ways to strengthen the newborn health component of maternal and child health programmes are being organized in Bangkok (15-17 November 2005) and New Delhi (5-9 December 2005). (who.int)
This sequestration of infected erythrocytes results in maternal anemia and low birthweight (LBW) ( 4 - 6 ), as well as consequences for child health ( 7 - 10 ). (cdc.gov)
Fetal development within the on cognitive function, social behaviour, maternal environment and work performance, immunocompetence neonatal period and reproductive health [ 5,6 ]. (who.int)
Sudden indulgence in strenuous exercises can endanger fetal and maternal health. (childhealth-explanation.com)
The Solomon Islands Government through the Ministries of Health and Medical Services, Agriculture and Livestock (MAL), Fisheries and Marine Resources (MFMR) and Education and Human Resources (MEHRD) wish to acknowledge the many persons, institutions and organizations involved in the development of this policy for their contributions through insights and experiences and for taking this document to its present status. (who.int)
Because the amino acids contained within protein are essential to healthy cell growth, eating enough protein during pregnancy is important both for fetal development and the overall health of the pregnant person while the body is undergoing so much change. (whattoexpect.com)
Thus, changes to placental fatty acid transport have serious implications for fetal growth and long-term health. (tufts.edu)
According to the Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH), FAS is a fetal disorder caused by maternal alcohol consumption during pregnancy. (neurosciencenews.com)
Research examining fetal health is overwhelmingly focused on maternal health," he said. (neurosciencenews.com)
Higher maternal blood pressure in pregnancy is associated with chemical modifications to placental genes, according to a study by researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health (NIH). (nih.gov)
NICHD leads research and training to understand human development, improve reproductive health, enhance the lives of children and adolescents, and optimize abilities for all. (nih.gov)
Pregnancy in young onset Parkinson's disease (YOPD) does not often occur, yet the medication in this condition is critical for maternal and fetal health. (biorxiv.org)
In the intervening two decades new scientific research has shown that the PCBs that build up in fish and people are more potent cancer-causing agents than originally believed, and that they present other health risks as well, in particular neurodevelopmental risks to unborn children from maternal consumption of PCB-contaminated fish. (ewg.org)
This study provides evidence of distinct patterns of fetal abdominal growth and placental transfer and how they relate to longer term health. (ox.ac.uk)
In a recent study published in BRAIN , researchers evaluated the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on fetal brain health. (news-medical.net)
To determine the frequency of subclinical hypothyroidism in pregnant women treated in maternal and child services of the Ministry of Public Health. (bvsalud.org)
Factors that may play a Malnutrition represents the number one risk factor in the role in modulating malnutrition include maternal health global burden of disease ( 1 ). (who.int)

Here, we identify a molecular mechanism for detrimental effects of low maternal n-3 PUFA intake on hippocampal development in mice. (nature.com)
Previous studies show that maternal choline supplementation normalizes fetal growth and adiposity of progeny from obese mice. (cuny.edu)

A suggested explanation for this association is intrauterine programming in response to maternal malnutrition. (nih.gov)
There is a modest positive association between birth weight and lung function which indicates that intrauterine factors might have a role in lung development. (bmj.com)

To understand the mechanisms by which n-3/n-6 PUFA imbalance affects CNS development, we investigated the impact of maternal dietary n-3 PUFA deficiency on offspring's microglia, the resident immune cells involved in CNS development and homeostasis 11 . (nature.com)

Undernutrition slows cell division either as a direct effect or through altered concentrations of growth factors or hormones, of which insulin and growth hormone are particularly important. (bmj.com)
Insulin secreted by the fetal pancreas in response to maternal glucose concentrations is a key growth factor. (nih.gov)
The mechanisms regulating follicle growth and development are under the control of changing concentrations of ligands ( i.e. hormones and growth factors). (glowm.com)
Previously we found that certain fetal imprinted genes represented as an allele score are associated with maternal pregnancy glucose concentrations. (biomedcentral.com)
Recently it was reported that fetal polymorphisms with strong associations with birth weight tend to mediate these independently of increases in maternal pregnancy glucose concentrations. (biomedcentral.com)
We therefore investigated whether potential associations between the fetal allele score and birth weight were related to maternal glucose concentrations in the Cambridge Baby Growth Study. (biomedcentral.com)
This association was partially attenuated by adjusting for maternal glucose concentrations (β = 50 (4-95) g/risk allele, β′ = 0.089, p = 0.03, n = 405). (biomedcentral.com)
Genetics can have roles in regulating both maternal glucose concentrations in pregnancy and fetal growth expressed as offspring birth weight. (biomedcentral.com)
However none of the fetal variants used to construct the gene score in this study were independently associated with maternal glucose concentrations. (biomedcentral.com)
In the current study we therefore examined relationships between our fetal imprinted gene allele score and measures of size at birth, in particular investigating whether any allele score associations with size at birth appear to be attenuated by maternal glucose concentrations in pregnancy. (biomedcentral.com)

Abnormal vascular development during fetal life and early childhood, as a result of genetic insulin resistance, could also explain the increased risk of hypertension and vascular disease. (nih.gov)

The researchers conducted a comprehensive genetic analysis, called an epigenome-wide association study (EWAS), on biopsies of placentas delivered from 301 pregnant women in the NICHD Fetal Growth Study . (nih.gov)
Especially in normal weight pregnant women, the heavier the weight of the newborn babies as the second trimester of pregnancy weight gain, the less significant the weight gain in the first trimester of pregnancy and fetal growth. (researchsquare.com)
In twin pregnancy, regardless of the pre-pregnant body mass index, maternal weight gain affected fetal growth. (researchsquare.com)
Our pilot study took a step further and demonstrated that cord blood level of PFBS is associated with lower levels of free thyroxine (FT4) and thyroid-stimulating hormone (TSH) in both maternal and cord blood in our pregnant human cohort. (duke.edu)

Not all fetuses that are SGA are pathologically growth restricted and, in fact, may be constitutionally small. (medscape.com)
Similarly, not all fetuses that have not met their genetic growth potential are in less than the 10th percentile for estimated fetal weight (EFW). (medscape.com)
Examples include fetuses with trisomy 18, cytomegalovirus infection, or fetal alcohol syndrome. (medscape.com)
In a cohort study in Sweden, a 10-fold increase in late fetal deaths was found among very small fetuses. (medscape.com)
At E17.5, BS reduced fetal adiposity and prevented liver triglyceride overaccumulation in HF versus NF fetuses (P (cuny.edu)

In this study, we investigate the impact of maternal nutrition on post-implantation trophoblast phenotype and fetal growth. (manchester.ac.uk)
These data demonstrate that early post-implantation embryos modify trophoblast phenotype to regulate fetal growth under conditions of poor maternal nutrition. (manchester.ac.uk)

Thyroid hormones regulate multiple metabolic processes and play an essential role in normal growth and development, and normal maturation of the central nervous system and bone. (nih.gov)

Our results show that maternal dietary n-3 PUFA deficiency increases microglia-mediated phagocytosis of synaptic elements in the rodent developing hippocampus, partly through the activation of 12/15-lipoxygenase (LOX)/12-HETE signaling, altering neuronal morphology and affecting cognitive performance of the offspring. (nature.com)

Maternal, placental, and fetal samples were collected for metabolite and gene-expression assays. (cuny.edu)
The full paper, ' Association between fetal abdominal growth trajectories, maternal metabolite signatures early in pregnancy, and childhood growth and adiposity: prospective observational multinational INTERBIO-21st fetal study ', can be read in The Lancet Diabetes & Endocrinology . (ox.ac.uk)

Consequences include maternal anemia and fetal growth retardation. (cdc.gov)

Monogenic diseases that impair sensing of glucose, lower insulin secretion, or increase insulin resistance are associated with impaired fetal growth. (nih.gov)

A new study, led by researchers at the University of Oxford, UK, in collaboration with the University of California, Berkeley, USA, published in The Lancet Diabetes & Endocrinology identifies, as early as the 5th month of pregnancy, patterns of fetal abdominal growth associated with maternal lipid metabolites that track newborn growth, adiposity and development into childhood. (ox.ac.uk)

The authors believe their study is the first EWAS to compare placental DNA methylation to maternal blood pressure across trimesters. (nih.gov)

The collected data were analyzed using SPSS version 23 statistical package, and multiple logistic regression was carried out to determine the effect of maternal age and parity with respect to LBW. (bvsalud.org)

The prolactin (PRL) and growth hormone (GH) gene families represent species-specific expansions of pregnancy-associated hormones/cytokines. (biomedcentral.com)
Although we previously reported that maternal choline supplementation downregulated mRNA expression of genes involved in de novo lipogenesis in fetal livers, such alterations were not observed with BS, suggesting differential effects of betaine and choline on fetal gene expression. (cuny.edu)
The fetal imprinted gene allele score was positively associated with birth weight (β = 63 (17-109) g/risk allele, β′ = 0.113, p = 7.6 × 10 −3 , n = 405). (biomedcentral.com)
These results suggest that associations between the fetal imprinted gene allele score and size at birth are mediated through both glucose-dependent and glucose-independent mechanisms. (biomedcentral.com)

Invasion of placental trophoblast cells into the maternal spiral arteries is too shallow, leading to inadequate placental perfusion and hypoxia [ 11 , 12 ]. (hindawi.com)

ME Conferences, would like to invite you to attend the International Conference on Fetal and Maternal Medicine scheduled to take place in Istanbul, Turkey on May 30-31, 2019. (aztechcouncil.org)
In the present study, researchers assessed the effects of coronavirus disease 2019 (COVID-19) on fetal brain tissues. (news-medical.net)
Only two similar cases with cortical hemorrhages were observed among 300 randomly chosen specimens out of 4,917 specimens sourced from the human development biology resource between September 1999 and December 2019. (news-medical.net)
Estudio retrospectivo, descriptivo de corte transversal, de muestreo no probabilístico, en gestantes que tuvieron su parto en servicios de la red del Ministerio de Salud Pública, entre el 1 de enero de 2017 y el 31 de diciembre de 2019. (bvsalud.org)

We have demonstrated that a mouse maternal low-protein diet (LPD) fed exclusively during preimplantation development (Emb-LPD) increases offspring growth but programmes adult cardiovascular and metabolic disease. (manchester.ac.uk)

Maternal betaine supplementation affects fetal growth and lipid metabo" by Yaelle Joselit, Khatia Nanobashvili et al. (cuny.edu)
Developmental, or fetal, programming is the idea that the maternal environment affects fetal development and the offspring long-term. (unl.edu)

Cessation early in pregnancy eliminates the adverse effects of smoking on fetal growth. (cdc.gov)
The researchers monitored the growth inside the womb of over 3,500 babies in six countries (Brazil, Kenya, Pakistan, South Africa, Thailand, and the United Kingdom) using serial fetal ultrasound scans throughout pregnancy, and analysed blood samples taken from the women early in pregnancy and from the umbilical cord at birth. (ox.ac.uk)

Adverse fetoplacental environments profoundly impact fetal growth and development. (cdc.gov)

Growth depends on nutrients and oxygen, and the fetus's main adaptation to lack of these is to slow its rate of cell division, especially in those tissues that are undergoing critical periods at the time. (bmj.com)
Disproportionate growth can occur because different tissues have critical periods of growth at different times. (bmj.com)
During the course of folliculogenesis, growth is achieved by cell proliferation and formation of follicular fluid, whereas development involves cytodifferentiation of all the cells and tissues in the follicle. (glowm.com)
The study was conducted between July 2020 and mid-April 2022 in the United Kingdom (UK), wherein human fetal tissues aged 9.0 to 21.0 pcw (post-conception weeks) were obtained from the HDBR (human development biology resource). (news-medical.net)
In addition, SARS-CoV-2 was present sparsely in the placental, umbilical cord and amniotic tissues, indicating SARS-CoV-2 presence in maternal and fetal tissues. (news-medical.net)

Fetal origins of. (bmj.com)
The programming of blood pressure, insulin responses to glucose, cholesterol metabolism, blood coagulation, and hormonal settings are all areas of active research.The BMJ's recent editorial on the fetal origins hypothesis stated that it rests only on the "very general" proposition that fetal undernutrition causes coronary heart disease. (bmj.com)

Placental outflow pressure was measured to assess perfused vascular resistance, in which, exposed fetal females demonstrated a significantly decreased outflow pressure (3.97 +/- 1.30 mm Hg) in the presence of the thromboxane mimetic, U46619, compared to sham-control fetal females (9.10 +/- 1.07 mm Hg) and nano-TiO2 exposed fetal males (9.96 +/- 0.66 mm Hg). (cdc.gov)
The predisposition to NIDDM and vascular disease is likely to be the result of both genetic and fetal environmental factors. (nih.gov)

Placentas exhibit signs of adaptation to stress, including larger maternal blood spaces and increased expression of nutrient transporter genes. (elifesciences.org)
Folic acid (also known as vitamin B9 or folate) is a nutrient that helps cell growth and maintenance. (jeancoutu.com)

Nano-TiO2 exposed fetal females demonstrated significantly increased TXB2 production (11186.48 +/- 189.92 pg/ml) from LZ tissue compared to female sham-control (483.77 +/- 86.09 pg/ml) and male exposed (598.39 +/- 135.69 pg/ml). (cdc.gov)
Among other things, this vitamin promotes maternal and foetal tissue growth during pregnancy. (jeancoutu.com)

We have previously reported that a maternal dietary n-3 PUFA deficiency alters the microglial phenotype and reduces their motility in the developing hippocampus 17 . (nature.com)

La frecuencia de hipotiroidismo en las mujeres paraguayas justifica ampliar la cobertura de detección y tratamiento oportuno para evitar el hipotiroidismo congénito y sus resultados adversos, prevenibles con una adecuada atención prenatal. (bvsalud.org)

Background: Birth weight is the most important factor determining the survival, growth and development of a newborn. (bvsalud.org)

Indeed particularly prior to the third trimester of pregnancy when its glucoregulatory function develops, the principal roles of fetal insulin are both mitogenic and anabolic, such as enhancing the growth of white adipocytes and stimulating triglyceride production and deposition in them [ 5 ]. (biomedcentral.com)

Golding said this research, which was funded by a Medical Research Grant from the W.M. Keck Foundation and the NIH National Institute on Alcohol Abuse and Alcoholism, reveals a potential blind spot in the current diagnostic criteria for FAS, the most severe form of Fetal Alcohol Spectrum Disorder (FASD), which requires documentation of maternal alcohol use during pregnancy. (neurosciencenews.com)
Previous studies have reported that maternal SARS-CoV-2 infections and immunological responses elevate the risk of altered fetal brain development, fetal death, growth restrictions and severe pathologies such as intraventricular hemorrhages and pneumonia. (news-medical.net)

Anatomy30

Organisms15

Diseases17

Chemicals and Drugs16

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Psychiatry and Psychology1

Phenomena and Processes49

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture1

Information Science3

Named Groups3

Health Care1

Gestation14

Outcomes9

Cause of maternal and fetal2

Restriction5

Morbidity and morta1

Exposure17

Utero2

Placenta8

Obesity5

Perinatal4

Effects of maternal1

Gestational6

Mortality3

Miscarriage2

Fetus8

Affect fetal1

Crecimiento Fetal1

Pregnancies4

Health23

Mice2

Intrauterine2

Investigated the impact of maternal1

Concentrations10

Abnormal1

Pregnant4

Fetuses5

Nutrition2

Regulate1

Show that maternal1

Metabolite2

Include maternal1

Secretion1

Endocrinology1

Methylation1

Effect of maternal1

Gene4

Trophoblast1

20194

Increases1

Affects2

Early in pregnancy2

Adverse1

Tissues5

Origins2

Vascular2

Nutrient2

Tissue2

Phenotype1

Prenatal1

Newborn1

Insulin1

Severe2