• The role of glutamatergic medial amygdala neurons in male rat sexual behavior. (uit.no)
  • A cell-by-cell study of the amygdala, a brain structure vital in controlling emotional reactions, has exposed previously unobserved links between addiction behaviors and genes related to energy metabolism, suggesting energy management in neurons could influence addiction-like actions. (neurosciencenews.com)
  • Scientists have discovered that somatostatin-expressing neurons in the amygdala help distinguish between good and bad stimuli, responding differently to rewards versus punishments and even different types of rewards. (neurosciencenews.com)
  • In people with PTSD, during REM sleep norepinephrine and serotonin levels remain high, reducing the brain's ability to inhibit fear-expression neurons through neural rhythms sent between the prefrontal cortex and amygdala. (neurosciencenews.com)
  • Here we leveraged human single neuron recordings in ventromedial prefrontal, dorsomedial frontal, hippocampus and amygdala neurons while patients performed a sequential Pavlovian condi. (researchgate.net)
  • We found that supraoptic oxytocin neurons extend their dendrites into the medial amygdala and that this dendritic oxytocin system mediates social recognition. (nii.ac.jp)
  • His team showed that altering neurons that extended from a subregion called the bed nucleus of the stria terminalis (BNST) to another brain area - the preoptic hypothalamus - could turn male mice's ability to recognize the sex of another mouse on and off like a light switch. (technologynetworks.com)
  • We also assessed the role of basolateral amygdala (BLA) and dorsal medial prefrontal cortex (dmPFC). (nature.com)
  • Based on previous findings with heroin and cocaine, in the present study we assessed the roles of central and basolateral amygdala (CeA and BLA, respectively), ventral and dorsal medial prefrontal cortex (vmPFC and dmPFC, respectively), and orbitofrontal cortex (OFC) in incubation of methamphetamine craving. (nature.com)
  • The basolateral amygdala (BLA) is critical for the formation of emotional memories. (nih.gov)
  • The researchers found a new CRH-sensitive connection coming from the basolateral amygdala into the nucleus accumbens in the brains of mice. (nih.gov)
  • The basolateral amygdala is a brain area involved in learning the association between an experience (good or bad) and an outcome. (nih.gov)
  • Together, the findings of this study provide evidence that the newly discovered connection between the basolateral amygdala and the nucleus accumbens is involved in reward-behavior deficits associated with early life adversity. (nih.gov)
  • Based on previous results, we hypothesized that temporal desynchronization between the dorsal hippocampus (DHc) and the basolateral amygdala (BLA), during memory retrieval, could be responsible for this impairment. (bvsalud.org)
  • This study examined the reinforcement omission effects on behavioral repertoire of rats with lesions in the central nucleus and basolateral complex of the amygdala, using classical conditioning and non-contingent reinforcement schemes. (bvsalud.org)
  • reinforcement omission, behavioral repertoire, central nucleus of the amygdala, basolateral complex of the amygdala. (bvsalud.org)
  • Anatomically, the amygdala and more particularly its central and medial nuclei, have sometimes been classified as a part of the basal ganglia. (wikipedia.org)
  • Here we studied the role of central amygdala (CeA), ventral medial prefrontal cortex (vmPFC), and orbitofrontal cortex (OFC), brain regions implicated in incubation of cocaine and heroin craving, in incubation of methamphetamine craving. (nature.com)
  • In the medial subdivision of the bed nucleus of the stria terminalis (BST) and the central amygdala (CeA), the number of pCREB immunoreactive (pCREB-ir) cells in the clean-bedding exposed group was significantly larger than in the home cage group, while the number of pCREB-ir cells in the OVX+E2-bedding exposed group did not differ from that in the home cage group. (nel.edu)
  • The fear state that potentiates this reflex is subserved by the amygdala, and the potentiation itself depends on direct and indirect projections from the central nucleus and medial nucleus of the amygdala to the startle circuit at the level of the pons (Davis, 2006). (zurichhotelscentre.com)
  • The present study was designed to analyze whether the ARd changes in these and other brain areas, such as the medial amygdala (MeA) and lateral septum, ventral part (LSV), were associated with changes in sexual behavior following sexual satiety. (karger.com)
  • Statistical between-group comparisons of deformation maps showed that patients treated with lithium exhibited significantly increased volumes of the amygdala and hippocampus compared with patients who were not taking lithium. (nih.gov)
  • Particularly, while the CORT + DFP rats had more restricted spatial patterns in the hippocampus and the hypothalamus, the highest and most wide-spread differences were shown in DFP-treated rats compared to the controls in the thalamus, the amygdala, the piriform cortex and the ventral tegmental area. (cdc.gov)
  • In contrast, stimulation of the left amygdala was able to induce either pleasant (happiness) or unpleasant (fear, anxiety, sadness) emotions. (wikipedia.org)
  • Other evidence suggests that the left amygdala plays a role in the brain's reward system. (wikipedia.org)
  • There are observable developmental differences between the right and left amygdala. (wikipedia.org)
  • The left amygdala reaches its developmental peak approximately 1.5-2 years prior to the right amygdala. (wikipedia.org)
  • Despite the early growth of the left amygdala, the right increases in volume for a longer period of time. (wikipedia.org)
  • It is inferred that the early development of the left amygdala functions to provide infants the ability to detect danger. (wikipedia.org)
  • The reverse, with more neural connections in the left amygdala, was the case in gay men and straight women. (themoneytimes.com)
  • Older age was associated with increase in MOR availability in frontotemporal areas but decrease in amygdala, thalamus, and nucleus accumbens. (iasp-pain.org)
  • They identified a new connection between the amygdala and the nucleus accumbens in the brains of mice that is sensitive to early life adversity and affects how mice respond to rewards. (nih.gov)
  • The connection was distinct from other well-documented connections between the amygdala and nucleus accumbens. (nih.gov)
  • Stimulating the amygdala-nucleus accumbens connection reduced reward-related behaviors in male but not female mice, suggesting this connection inhibits reward behavior-but only in male mice. (nih.gov)
  • To test the role of this connection on reward-behavior deficits associated with early life adversity, the scientists blocked the connection between the amygdala and the nucleus accumbens in mice that had been exposed to early life stress. (nih.gov)
  • The regions described as amygdala nuclei encompass several structures of the cerebrum with distinct connectional and functional characteristics in humans and other animals. (wikipedia.org)
  • Studies show that the activation of some amygdala nuclei may be involved in the modulation of these processes. (bvsalud.org)
  • The amygdala is connected with the prefrontal cortex, an area involved with our highest intellectual properties, and receives sensory inputs from it all the time. (typepad.com)
  • Based on evidence for structural and functional preservation of the amygdala in older adults and findings that older adults show greater prefrontal cortex activity than younger adults while engaging in emotion-processing tasks, we argue that the cognitive control hypothesis is a more likely explanation for older adults' positivity effect than the aging-brain model. (researchgate.net)
  • Serfling G, Buades-Rotger M, Harbeck B, Kramer UM, Brabant G. The corticosteroid prednisolone increases amygdala and insula reactivity to food approach signals in healthy young men. (medscape.com)
  • Heritability of amygdala reactivity to angry faces and its replicable association with the schizophrenia risk locus of miR-137. (cdc.gov)
  • And while there are two units (left and right sides of the brain) to the amygdala, it is more often discussed as if it were one organ, so the singular term "amygdala", and the common usage plural "amygdalas," not the Latin plural "amygdalae" is used here and throughout most of the medical literature. (typepad.com)
  • Shown to perform a primary role in the processing of memory, decision making, and emotional responses (including fear, anxiety, and aggression), the amygdalae are considered part of the limbic system. (wikipedia.org)
  • Norepinephrine (NE) is thought to play a key role in fear and anxiety, but its role in amygdala-dependent Pavlovian fear conditioning, a major model for understanding the neural basis of fear, is poorly understood. (frontiersin.org)
  • Exposing the mice to aspartame also produced changes in the expression of genes regulating excitation-inhibition balance in the amygdala, a brain region that regulates anxiety and fear. (medscape.com)
  • The anxiety, its response to diazepam, and the changes in amygdala gene expression are not limited to the aspartame-exposed individuals but also appear in up to two generations descending from the aspartame-exposed males," the researchers report. (medscape.com)
  • Insomnia can increase anxiety and affects the amygdala, which is the part of the brain responsible for regulating emotions. (holisticwisdom.com)
  • Using structural magnetic resonance imaging we assessed whether lithium treatment was associated with differences in amygdala and hippocampal volumes in a sample of bipolar adults. (nih.gov)
  • Amygdala and hippocampal volumes were analyzed using tensor-based morphometry. (nih.gov)
  • UVA Health researchers have developed a powerful new tool to understand how medications affect men and women differently, and that will help lead to safer, more effective drugs in the future. (medicalxpress.com)
  • Before developing their model, the researchers first looked at the federal Food and Drug Administration's Adverse Event Reporing System to evaluate the frequency of reported liver problems in men and women. (medicalxpress.com)
  • These cutting-edge liver simulations provided important insights into how drugs affect the tissue differently in men and women and allowed the researchers to understand why. (medicalxpress.com)
  • Researchers crafted a detailed atlas of the amygdala, revealing new insights into emotional responses and potential treatments for cocaine addiction. (neurosciencenews.com)
  • With a sharper focus on these amygdala-brainstem links, researchers forge a vital pathway toward demystifying SUDEP, revealing robust avenues for future exploration, preventive measures, and targeted treatments. (neurosciencenews.com)
  • Researchers at the University of Toronto say that differences between men and women on some tasks that require spatial skills are largely eliminated after both groups play a video game for only a few hours. (wikipedia.org)
  • Researchers at the University of Iowa found that the thicker grey matter in the parietal lobe of females led to a disadvantage in mental rotations, and that the larger surface areas of the parietal lobe of males led to an advantage in mental rotations. (wikipedia.org)
  • The researchers studied 359 men, ages 57 to 66 years old, participating in the Vietnam Era Twin Study of Aging (VETSA). (neurosciencenews.com)
  • To determine whether this connection plays a role in reward-related behaviors, the researchers stimulated it in male and female mice using chemical (chemogenetic) and light-based (optogenetic) methods, which can turn off and on the action of nerve cells in the brain. (nih.gov)
  • Researchers at Stanford University have identified a brain hub that controls sexual arousal in male mice. (technologynetworks.com)
  • Researchers hope that this line of study could lead to treatments for sexual problems in human men. (technologynetworks.com)
  • The researchers bred a group of male, virgin mice who were kept in isolation from female mice after they were weaned a few weeks after birth to rule out any social influences on their behavior. (technologynetworks.com)
  • Researchers have been quietly accumulating massive amounts of data comparing male and female brains, but it's only the differences that get hyped," Dr. Eliot continued. (rosalindfranklin.edu)
  • Bipolar patients who received emotion-focused therapy showed increased connectivity and activation in the amygdala post-intervention compared to those who received cognitive behavioral therapy. (neurosciencenews.com)
  • The neuroscience of sex differences is the study of characteristics that separate the male and female brains. (wikipedia.org)
  • [2] A review from 2006 and a meta-analysis from 2014 found that some evidence from brain morphology and function studies indicates that male and female brains cannot always be assumed to be identical from either a structural or functional perspective, and some brain structures are sexually dimorphic . (wikipedia.org)
  • The ideas of differences between the male and female brains have circulated since the time of Ancient Greek philosophers around 850 BC. (wikipedia.org)
  • Through molecular, animal, and neuroimaging studies, a great deal of information regarding the differences between male and female brains and how much they differ in regards to both structure and function has been uncovered. (wikipedia.org)
  • The gender difference in spatial ability was found to be attributed to morphological differences between male and female brains. (wikipedia.org)
  • The brains of gay men look a lot like those of straight women and the brains of lesbians bear resemblance to those of straight men, says a new research that emphasizes the role of biology in sexual orientation. (themoneytimes.com)
  • We've singled out a circuit in male mammals' brains that controls sexual recognition, libido and mating behavior and pleasure," said Dr. Nirao Shah , a professor of psychiatry and of neurobiology at Stanford and the senior author of the study. (technologynetworks.com)
  • How different are men and women's brains? (rosalindfranklin.edu)
  • Men and women's brains do differ slightly, but the key finding is that these distinctions are due to brain size, not sex or gender," Dr. Eliot said. (rosalindfranklin.edu)
  • The unusually large study of studies, " Dump the 'dimorphism': Comprehensive synthesis of human brain studies reveals few male-female differences beyond size ," published in Neuroscience and Biobehavioral Reviews, finds that size is the only clear-cut difference between male and female brains. (rosalindfranklin.edu)
  • Male-female brain differences are also poorly replicated between diverse populations, such as Chinese versus American, meaning there is no universal marker that distinguishes men and women's brains across the human species. (rosalindfranklin.edu)
  • DESIGN: We conducted 2 cross-sectional studies of amygdala volume, measured blind to diagnosis on high-resolution, anatomical magnetic resonance images. (virginia.edu)
  • By tweaking signaling in this area, the team was able to enhance or extinguish sexual desire and even let male mice engage in sexual activity immediately after ejaculation. (technologynetworks.com)
  • The results showed that 48 h after sexual satiety 30% of the males displayed a single ejaculation and the remaining 70% showed a complete inhibition of sexual behavior. (karger.com)
  • Shah's previous work explored connections from the brain's emotional center - the amygdala. (technologynetworks.com)
  • The amygdala is larger in males than females, in children aged 7 to 11, adult humans, and adult rats. (wikipedia.org)
  • In females, maternal exposure to IPV was associated with a smaller amygdala, a brain area associated with social and emotional development. (neurosciencenews.com)
  • In 1854, German anatomist Emil Huschke discovered a size difference in the frontal lobe , where male frontal lobes are 1% larger than those of females. (wikipedia.org)
  • Females show enhanced information recall compared to males. (wikipedia.org)
  • This may be due to the fact that females have a more intricate evaluation of risk-scenario contemplation, based on a prefrontal cortical control of the amygdala . (wikipedia.org)
  • For example, the ability to recall information better than males most likely originated from sexual selective pressures on females during competition with other females in mate selection. (wikipedia.org)
  • ASPD is also more likely to occur in males than in females. (medicalnewstoday.com)
  • The present results demonstrated that males presented a higher initial level of analgesia, but a poorer maintenance of analgesic effect after the EACP procedure, while females demonstrated a long lasting analgesic effect even after discontinuation of EACP. (bvsalud.org)
  • The duration of this analgesic effect seems to be different for males and females. (bvsalud.org)
  • In another experiment, males were tested for recovery of sexual behavior 48 h, 72 h or 7 days after sexual satiety. (karger.com)
  • The results are discussed on the basis of the similarities and discrepancies between ARd in specific brain areas and male sexual behavior. (karger.com)
  • Buvat J: Hormones and male sexual behavior: physiological and physiopathological data. (karger.com)
  • RESULTS: In study 1, individuals with autism who had small amygdalae were slowest to distinguish emotional from neutral expressions (P=.02) and showed least fixation of eye regions (P=.04). (virginia.edu)
  • 7 subsystems are altered by sex in both the liver and kidney, with 6 upregulated in males in both tissue types, and 1 upregulated in the female liver and male kidney. (medicalxpress.com)
  • Central obesity is characterized by increased adipose tissue in the mediastinum and peritoneum and an increased waist-to-hip ratio of greater than 1 in men and higher than 0.8 in women. (medscape.com)
  • New York, Oxford University Press, 2011] proposes that older adults' positivity effect is a consequence of age-related decline in the amygdala, whereas the cognitive control hypothesis [Kryla-Lighthall and Mather in: Handbook of Theories of Aging, ed 2. (researchgate.net)
  • The right hemisphere of the amygdala is associated with negative emotion. (wikipedia.org)
  • More attention was paid on the amygdala, an almond-shaped structure inside each hemisphere of the brain, which is associated with processing and storing emotions. (themoneytimes.com)
  • Study 2 also replicated findings of more gaze avoidance and childhood impairment in participants with autism with the smallest amygdalae. (virginia.edu)
  • CONCLUSIONS: These findings best support a model of amygdala hyperactivity that could explain most volumetric findings in autism. (virginia.edu)
  • Across hundreds of such studies, Dr. Eliot's team found extremely poor reliability in sex difference findings - nearly all specific brain areas that differed in activity between men and women were not repeated across studies. (rosalindfranklin.edu)
  • We are the only international conversation about the changing roles of men in the 21st century. (goodmenproject.com)
  • Adolescents and teens think and manage situations with their amygdalae, which serves a few roles: the processing of memory, decision making and processing emotional reactions. (mytpi.com)
  • The right amygdala is associated with response to fearful stimuli as well as face recognition. (wikipedia.org)
  • Study reveals heightened activity in the amygdala in response to seeing surprised or neutral facial expressions could be a biomarker for a risk of developing PTSD following trauma. (neurosciencenews.com)
  • Summary: A new neuroimaging study reveals middle aged men who experience negative fateful life events, such as the death of a loved one or divorce, show signs of accelerated brain aging. (neurosciencenews.com)
  • The amygdala may very well do this by helping the brain identify salient points of new inputs (whether they have red or green flags indicating either danger or reward) and to prioritize them by the use of the "magnitude dial" of the amygdale (important enough to pay close attention, or not so important or threatening and therefore, something to ignore). (typepad.com)
  • We're hopeful these approaches will be help address many other questions where men and women have differences in drug responses or disease processes," Papin said. (medicalxpress.com)
  • The study elucidates how seizures originating in specific amygdala subregions might suppress both breathing and the crucial alarm signal of "air hunger," potentially through novel connections to the brainstem, which regulates responses to blood CO2 alterations. (neurosciencenews.com)
  • In childhood, the amygdala is found to react differently to same-sex versus opposite-sex individuals. (wikipedia.org)
  • MAIN OUTCOME MEASURES: Amygdala volume, judgment of facial expressions, and eye tracking. (virginia.edu)
  • In one study, electrical stimulations of the right amygdala induced negative emotions, especially fear and sadness. (wikipedia.org)
  • Study 2 showed smaller amygdalae in individuals with autism than in control subjects (P=.03) and group differences in the relation between amygdala volume and age. (virginia.edu)
  • They do note that the study was a snapshot of a narrow demographic: older, predominantly white, males. (neurosciencenews.com)
  • The amygdala comprises two almond-sized-and-shaped portions of the mid-brain, that are becoming more and more common targets for study. (typepad.com)
  • The study of the function of the amygdale has helped resolve one of the great debates in neuroscience over the last 250 years: Whether the Body (in this case, the amygdala and the brain) governed the Mind (in this case, the sense of consciousness, self-awareness, thought processing, learning and memory), or whether these were two truly distinct operations. (typepad.com)
  • According to the Swedish study, the two hemispheres of the brain were of similar size in Gay men and heterosexual women, while the right side was bigger in lesbian women and heterosexual men. (themoneytimes.com)
  • The study, published in the Proceedings of the National Academy of Sciences journal, involved 90 men and women, including homosexuals and heterosexuals of both genders. (themoneytimes.com)
  • this study says 13% of men were gay. (scienceforums.net)
  • In the current study, the investigators tested different dosages of spironolactone on binge-like alcohol consumption in male and female mice and assessed food and water intake, blood alcohol levels, motor coordination, and spontaneous locomotion. (medscape.com)
  • OBJECTIVE: To evaluate amygdala volume in individuals with autism spectrum disorders and its relationship to laboratory measures of social behavior to examine whether variations in amygdala structure relate to symptom severity. (virginia.edu)
  • The right and left portions of the amygdala have independent memory systems, but work together to store, encode, and interpret emotion. (wikipedia.org)
  • The reduced rewards-behavior seen in male mice when the connection was stimulated was similar to reward-behavior deficits seen in mice that had experienced early life stress. (nih.gov)
  • 0001) and sex, with female mice drinking more alcohol, compared to male mice ( F 1,13 = 6.05, P = .02). (medscape.com)
  • The volume of the amygdala, an olive-sized part of the temporal lobe that is important for social-emotional behaviors, is a mere 1% larger in men across studies. (rosalindfranklin.edu)
  • The right amygdala plays a role in the association of time and places with emotional properties. (wikipedia.org)
  • Attempts to link pathological features of the amygdala, which plays a key role in emotional processing, to autism have shown little consensus. (virginia.edu)
  • The new model has already provided unprecedented insights into the biological processes that take place in the liver-the organ responsible for detoxifying the body-in both men and women . (medicalxpress.com)
  • Participants were 54 males aged 8 to 25 years, including 23 with autism and 5 with Asperger syndrome or pervasive developmental disorder not otherwise specified, recruited and evaluated at an academic center for developmental disabilities and 26 age- and sex-matched community volunteers. (virginia.edu)
  • Across the combined sample, severity of social deficits interacted with age to predict different patterns of amygdala development in autism (P=.047). (virginia.edu)
  • And importantly, none of these size-related differences can account for familiar behavioral differences between men and women, such as empathy or spatial skills. (rosalindfranklin.edu)
  • There is considerable growth within the first few years of structural development in both male and female amygdalae. (wikipedia.org)
  • The structural development of the male amygdala occurs over a longer period than in women. (wikipedia.org)
  • Not all men who appear to be effeminate are homosexual, not all homosexuals are effeminate in appearance, your argument is trivially falsified not to mention nonsensical and smacks of a self hatred that suggests you need professional help. (scienceforums.net)
  • The age-dependent increase was stronger in males. (iasp-pain.org)
  • In studies in animal models, investigators said they found "an inverse correlation between alcohol drinking and the expression of the MR in the amygdala, a key brain region in the development and maintenance of AUD and addiction in general. (medscape.com)
  • In addition, the grey matter volume on the amygdala is predicted by testosterone levels, which may also contribute to the increased mass of the male amygdala. (wikipedia.org)
  • This method allows neuroscientists to see areas that "light up" during particular mental tasks and has been widely used to look for male-female differences during language, spatial and emotional tasks. (rosalindfranklin.edu)
  • Maternal separation (MS) in male rats produced memories resistant to labilization in adulthood. (bvsalud.org)
  • 18F-FDG amygdalar activity significantly decreased with age in men (r = - 0.278, P = 0.001), but not in women (r = 0.002, P = 0.983). (uzh.ch)
  • For a long while, I thought about this conversation and aboutmany similar discussions I've had with my patients and colleagues.It's obvious to anyone who studies male behavior that men demonstrateextraordinary skill in sales, mechanics, politics, medicine,finance, construction, and many other areas. (go.com)
  • Women need about 20 minutes to 2 hours more sleep than men because of hormones regulated by the adrenal glands, as well as testosterone levels. (holisticwisdom.com)
  • Lesbians and straight men were found to have more nerve connections in the right side of the amygdala, compared with the left. (themoneytimes.com)