Some propose a distinction between true macroglossia, when histologic abnormalities correlate with the clinical findings of tongue enlargement, and relative macroglossia, where histology does not provide a pathologic explanation for the enlargement. (wikipedia.org)
Macroglossia can be subdivided into two categories: true macroglossia and relative macroglossia, also known as pseudomacroglossia. (medscape.com)
The term "true macroglossia" refers to macroglossia caused by histologic abnormalities within the tongue secondary to an underlying condition, such as muscular hypertrophy and vascular malformation. (medscape.com)
Clinical appearance of "true macroglossia. (medscape.com)
The incidence of macroglossia has been reported as 11-60% in persons with Down Syndrome although the presence of true macroglossia has been questioned by some investigators. (intelligentdental.com)
Congenital5
Macroglossia may be caused by a wide variety of congenital and acquired conditions. (wikipedia.org)
Relevant examples pertaining to congenital syndromes include relative macroglossia associated with micrognathia in Pierre Robin syndrome and hypotonia in Down syndrome. (medscape.com)
Although the exact incidence of macroglossia in the general population is unknown (because the etiologies are too numerous to quantify), the condition is found in some congenital syndromes, such as Down syndrome (1 per 700 live births) and Beckwith-Wiedemann syndrome (0.07 per 1000 live births). (medscape.com)
Macroglossia can result from a wide range of congenital and acquired conditions, although it is most frequently the product of vascular malformations and muscular hypertrophy. (medscape.com)
Beckwith Wiedemann syndrome (BWS) is a rare, congenital overgrowth disorder that is characterized by macroglossia, anterior abdominal wall defects, visceromegaly, gigantism, and neonatal hypoglycaemia. (qxmd.com)
Umbilical hernia2
The most common presentation includes cold or mottled skin, macroglossia or umbilical hernia seen at the initial examination [15]. (symptoma.com)
The salient personal history included conception with assisted reproductive technology (ART), delivery by caesarean section due to suspected subclinical chorioamnionitis (week 28 +2 ), large weight and length for gestational age (at the 92th and 98th percentiles), umbilical hernia, mild macroglossia and hyaline membrane disease treated with one dose of surfactant. (analesdepediatria.org)
Hypoplasia1
10, 21- 23 Further support for this hypothesis comes from an experimental paradigm of RS in which mandibular hypoplasia and relative macroglossia precede palatal closure. (bmj.com)
Syndrome6
Apparent macroglossia can also occur in Down syndrome. (wikipedia.org)
The initial evaluation of all patients with macroglossia may involve abdominal ultrasound and molecular studies for Beckwith-Wiedemann syndrome. (wikipedia.org)
whilst Down syndrome is an example of relative macroglossia. (wikipedia.org)
Tongue reduction for macroglossia in Beckwith Wiedemann syndrome: review and application of new technique. (qxmd.com)
Although these retarded children all suffered from the same symptoms - the mental retardation, the age of presentation (usually 18 months), and enlarged tongues (macroglossia) - he announced that one group had what he called mongolism (today Down syndrome ) and another group had cretinism (today infant hypothyroidism ). (oup.com)
Macrosomia1
these include abdominal wall defects (such as abdominal wall opening and hernia, macrosomia , macroglossia, kidney problems, and creases near the ears. (alleydog.com)
Airway2
Macroglossia may cause obstruction of the oral airway, which is usually worsened when the patient lies supine, allowing an enlarged tongue base to more directly block the oropharynx and hypopharynx. (medscape.com)
Factors affecting upper-airway size or patency include numerous anatomic variants and abnormalities (eg, nasal obstruction, retrognathia, macroglossia ), obesity, alcohol or sedative intake, and body position during sleep. (medscape.com)
Refers1
In general, macroglossia, meaning large tongue, refers to the protrusion of the tongue beyond the alveolar ridge or teeth. (medscape.com)
Protrusion1
Reduction for macroglossia is indicated for persistent protrusion or to allow correction of malocclusion. (lww.com)
Pseudomacroglossia1
The two broadest categories under the heading of macroglossia relate to true tongue enlargement and pseudomacroglossia. (medscape.com)
Reduction1
This video demonstrates how to perform a tongue reduction using a Y-V advancement technique for pediatric macroglossia. (csurgeries.com)
Palatal1
There is agreement, however, on the presence of a relative macroglossia due to the small palatal space and hypotonic tongue. (intelligentdental.com)
Enlargement3
Treatment and prognosis of macroglossia depends upon its cause, and also upon the severity of the enlargement and symptoms it is causing. (wikipedia.org)
Biopsies of small lesions in the anterior tongue can usually be safely performed in the clinic, but these small lesions are often not responsible for the global enlargement demonstrated in macroglossia. (medscape.com)
Nonetheless, the locoregional complications of macroglossia are generally the same relative to the magnitude of the enlargement and the size of the tongue. (medscape.com)
Difficulties1
Abnormal growth may also manifest as hemihyperplasia and/or macroglossia (leading to difficulties in feeding, speech and infrequently, sleep apnea). (orpha.net)
Prognathism1
Macroglossia may contribute to anterior open bite malocclusion with prognathism, speech articulation disturbances, drooling and the perception of intellectual disability. (qxmd.com)
Macroglossia is the medical term for an unusually large tongue. (wikipedia.org)
In relative macroglossia, an individual has a normal-sized tongue that, as a result of oral or skeletal abnormalities, such as a narrow mandible (as found in many head and neck syndromes), seems unusually large. (medscape.com)
Speech1
Speech and swallowing are also affected by macroglossia. (medscape.com)
Genetic1
Moreover, this condition is often genetic, so babies affected with macroglossia might often have the condition from birth. (twinstuff.com)
Classification1
The Myer classification subdivides macroglossia into generalized or localized. (wikipedia.org)
Mechanical1
Mechanical therapy may be useful in macroglossia with hypotonicity due to hypoglossal nerve deficit. (medscape.com)
Oral1
Note, in ( a ), the macroglossia, with the tongue protruding out of the mouth, and partial obstruction of the oral cavity. (radiologykey.com)
Large1
Macroglossia, meaning large tongue, has been documented for many centuries, with the earliest known description thought to be from around 1550 BC. (medscape.com)
Sign1
Macroglossia may be a sign of hypothyroid disorders. (wikipedia.org)
Mouth2
Macroglossia is a rare condition that enlarges the tongue out of the normal proportions of the mouth which makes the tongue stick out of the mouth. (twinstuff.com)
Due to macroglossia, mouth may remain slightly open. (symptoma.com)
Size1
Multiple shapes of keyhole tongue resection are utilized, depending on the size of the macroglossia. (medscape.com)
Medical term1
Macroglossia is a medical term used to describe a condition where the tongue is larger than normal. (dentalfreak.com)
Rare1
Labces de la base de langue est une entite tres rare quil faut suspecter devant une macroglossie aigue febrile.il sagit dune urgence medico-chirurgicale pouvant engager le pronostic vital. (researchbib.com)