AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceNamed GroupsHealth CareGeographicals
Portal VeinHypertension, PortalHypertensionHypertension, PulmonaryPortal SystemPortal PressureHypertension, RenalBlood PressureAntihypertensive AgentsHypertension, RenovascularHypertension, MalignantLiver CirculationHypertension, Pregnancy-InducedEsophageal and Gastric VaricesPortasystemic Shunt, SurgicalRisk FactorsOcular HypertensionSplenic VeinPulmonary ArteryRats, Inbred SHRReninLiver CirrhosisBlood Pressure DeterminationHemodynamicsMesenteric VeinsIntracranial HypertensionPortographyHepatic VeinsKidneyRats, Inbred WKYVascular ResistanceHepatic ArteryDesoxycorticosteroneVenous PressurePortacaval Shunt, SurgicalLiverHypertrophy, Right VentricularGastrointestinal HemorrhageSodium Chloride, DietaryPrevalenceBlood Pressure Monitoring, AmbulatoryMonocrotalinePregnancy Complications, CardiovascularAngiotensin IITime FactorsRenin-Angiotensin SystemTreatment OutcomeRats, Sprague-DawleyFollow-Up StudiesSplanchnic CirculationProspective StudiesDisease Models, AnimalAldosteroneVasodilator AgentsHeart RateRetrospective StudiesHyperaldosteronismLigationPseudotumor CerebriHypertrophy, Left VentricularCardiovascular DiseasesSodium, DietaryHypersplenismDiureticsSystoleChronic DiseaseDiet, Sodium-RestrictedNitric OxidePulmonary CirculationPortasystemic Shunt, Transjugular IntrahepaticSplenorenal Shunt, SurgicalRats, Inbred DahlHydrochlorothiazideSplenic ArteryNorepinephrineCross-Sectional StudiesDiabetes MellitusRenal Artery ObstructionAge FactorsMuscle, Smooth, VascularPersistent Fetal Circulation SyndromeEndothelin-1Cohort StudiesObesityAnoxiaRenal ArteryMasked HypertensionSodium ChlorideAngiotensin-Converting Enzyme InhibitorsLiver TransplantationPrehypertensionRegional Blood FlowAngiotensinogenSympathetic Nervous SystemAscitesVasoconstrictionVasoconstrictor AgentsRats, WistarVenous ThrombosisBody Weight
Significant portal hypertensionPulmonaryVein thrombosisCauses of portal hypertensionIdiopathicComplicationPortosystemic shuntCirrhosis and portalSinusoidal portal hypertensionComplicationsCirrhoticVaricealRetrospectiveDiagnosisAscitesCystic fibrosisHypertensiveClinicalAcute liver fOutcomesTransjugularControl HypertensionPrognosisBiliary obstructionSevereEsophagealObstructionSeverityHepatic encephalopathyAngiographyCSPHShuntsRecurrentCardiovascularProgressionPrehepaticDiabetesMortalityComorbiditiesUltrasoundHemodynamicConclusionOccur2021WorkupSecondaryAsymptomaticLiver transplantationSurvivalInfectionUnderwentChronic Liver DVenous systemHepatocellularSYSTEMATIC REVIEWDopplerTreatmentHVPGHeart failureHypersplenismEndoscopy
Significant portal hypertension5
  • Clinically significant portal hypertension (CSPH) is considered to be an HVPG ≥10 mm Hg, and severe portal hypertension is ≥12 mm Hg. (medscape.com)
  • To analyze the association between the liver uptake of gadoxetic acid (Gd-EOB-DTPA) in the hepatobiliary phase (HBP) in cirrhotic patients and the presence of clinically significant portal hypertension (CSPH), and how these features impact on HCC detection in the HBP. (radioloncol.com)
  • Here, we present a protocol for measurement of hepatic venous pressure gradient (HVPG),the gold standard to diagnose clinically significant portal hypertension. (jove.com)
  • The difference between FHVP and WHVP is referred to as HVPG, with values ≥10 mm Hg indicating clinically significant portal hypertension (CSPH). (jove.com)
  • 2. Severe chronic liver disease (Child Pugh C-grade), liver parenchymal disease with significant portal hypertension, and acute liver failure. (who.int)
Pulmonary18
  • Portopulmonary hypertension (PPH) is defined by the coexistence of portal and pulmonary hypertension. (wikipedia.org)
  • Once patients are symptomatic, they present with right heart dysfunction secondary to pulmonary hypertension and its consequent dyspnea, fatigue, chest pain and syncope. (wikipedia.org)
  • ET-1 is the most potent vasoconstrictor under investigation and it has been found to be increased in both cirrhosis and pulmonary hypertension. (wikipedia.org)
  • Rat models have shown decreased ET-B receptor expression in pulmonary arteries of cirrhotic and portal hypertensive animals, leading to a predominant vasoconstricting response to endothelin-1. (wikipedia.org)
  • citation needed] Finally, the pulmonary pathology of PPH is very similar to that of primary pulmonary hypertension. (wikipedia.org)
  • One study found at autopsy significant thickening of pulmonary arteries in cirrhotic patients. (wikipedia.org)
  • Thereafter, these patients are referred for pulmonary artery catheterization. (wikipedia.org)
  • citation needed] In general, the treatment of PPH is derived from the treatment of pulmonary hypertension. (wikipedia.org)
  • Patients with cystic fibrosis (CF) show decreased plasma concentrations of antioxidants due to malabsorption of lipid soluble vitamins and consumption by chronic pulmonary inflammation. (hindawi.com)
  • Chronic pulmonary infection of CF patients results in a chronic activation of immune cells, especially neutrophilic granulocytes, leading to a permanent production of free radicals and lipid peroxidation (LPO) products, thus triggering inflammation [ 3 - 6 ]. (hindawi.com)
  • In a number of studies, β -carotene supplementation in CF patients led to positive effects such as increase of total antioxidant capacity and decrease of pulmonary exacerbations [ 15 - 17 ]. (hindawi.com)
  • Thrombotic complications (arterial and venous events, including portal vein thrombosis (see this term) and pulmonary hypertension) have been described at a high rate after splenectomy. (orpha.net)
  • 2) Eisenmenger syndrome, (3) congenital heart disease without Eisenmenger syndrome, (4) idiopathic pulmonary arterial hypertension (IPAH), (5) cystic fibrosis, (6) chronic obstructive pulmonary disease (COPD) and/or emphysema), and (7) diffuse interstitial lung disease. (unican.es)
  • This study was undertaken to examine the association between TGF-β 1 gene polymorphisms and the development of pulmonary dysfunction in patients with cystic fibrosis. (bmj.com)
  • DISCUSSION TGF-β 1 genotypes may have a role in mediating pulmonary dysfunction in patients with cystic fibrosis. (bmj.com)
  • The life expectancy of patients with cystic fibrosis has been significantly increased with improvements in nutritional care and pulmonary therapies. (pucrs.br)
  • Pulmonary arterial hypertension (PAH) is a rare complication of primary Sjögren's syndrome (pSS). (biomedcentral.com)
  • AIMS: Remodelling of the extracellular matrix (ECM) is a key mechanism involved in the development and progression of heart failure (HF) but also functional in associated pulmonary hypertension (PH). (lu.se)
Vein thrombosis3
  • Patients with non-cirrhotic portal hypertension receiving EBL, other than EBL endoscopic treatment, previous transjugular intrahepatic portosystemic shunt (TIPS) implantation or orthotopic liver transplantation, occlusive portal vein thrombosis, patients with fundal varices only, patients with acute and/or uncontrolled variceal bleeding at baseline and insufficient medical/endoscopic records were excluded from this study. (springer.com)
  • It can also demonstrate portal flow and helps in diagnosing cavernous transformation of the portal vein, portal vein thrombosis, and splenic vein thrombosis. (medscape.com)
  • Ten women had a history of venous thrombosis, mostly portal vein thrombosis (N=7). (isth.org)
Causes of portal hypertension2
Idiopathic2
Complication2
Portosystemic shunt4
  • The etiology of portal hypertension may be an important factor affecting patient outcomes after transjugular intrahepatic portosystemic shunt (TIPS) treatment. (researchsquare.com)
  • Transjugular intrahepatic portosystemic shunt (TIPS) offers an effective treatment for patients with complications of portal hypertension, specifically prevention of variceal rebleeding and recurrent or refractory ascites. (emjreviews.com)
  • Congenital absence of the portal vein called a portosystemic shunt (aka Abernethy Malformation or liver shunt) causes blood to drain away from the portal system, and in turn the blood bypasses the liver. (portal-hypertension.com)
  • TIPS is minimally invasive method of creating a portosystemic shunt to decompress the portal venous system and method allows embolize tributaries (left gastric vein, short gastric vein) VVES and thereby reduce the risk of bleeding. (journalcra.com)
Cirrhosis and portal3
Sinusoidal portal hypertension3
  • Given the unique etiology and mechanism of sinusoidal portal hypertension in PA-HSOS patients and its high prevalence in China, We hypothsized that the different etiologies of portal hypertension with their underlying pathogenic mechanisms may result in different long-term survival after TIPS. (researchsquare.com)
  • Measurement of the hepatic venous pressure gradient (HVPG) is the gold standard to estimate portal venous pressure in patient with cirrhosis, i.e. assessing the severity of sinusoidal portal hypertension 4 . (jove.com)
  • Clinically, measurement of HVPG is indicated (i) to establish the diagnosis of sinusoidal portal hypertension, (ii) to identify patients at risk for hepatic decompensation by diagnosing CSPH (HVPG ≥10 mm Hg), (iii) to guide pharmacological therapy in primary or secondary prophylaxis of variceal bleeding, and (iv) to assess the risk of hepatic failure after partial hepatectomy 2 , 4 . (jove.com)
Complications10
  • A retrospective file review of 787 patients with portal hypertension-related complications, including 146 patients with PA-HSOS, who had received TIPS treatment at our institution between August 2008 to September 2020 was performed. (researchsquare.com)
  • Most adult patients present a mild anemia or a totally compensated hemolysis, with fatigue, icterus, splenomegaly and risks of secondary complications including cholelithiasis. (orpha.net)
  • Patients with cirrhosis are at risk for developing complications mostly related to portal hypertension (PHT), such as ascites or bleeding from gastric or esophageal varices 1 , 2 , 3 . (jove.com)
  • This review focusses on the optimisation of the use of a covered TIPS endoprosthesis in patients with portal hypertension-related complications, with consideration of evolving practices, patient selection, and multidisciplinary co-operation. (emjreviews.com)
  • 2 Elevated portal pressure increases cardiac output and reduces systemic vascular resistance, increasing blood flow and leading to serious complications. (emjreviews.com)
  • Treatment of portal hypertension focusses on preventing or managing complications and, at first-line, is dependent largely on pharmacological approaches, which include non-selective beta-blockers (NSBB). (emjreviews.com)
  • Liver injury or liver disease is usually asymptomatic until complications of liver failure or portal hypertension develop [ 15 ]. (biomedcentral.com)
  • With a clotted or as in the case of your daughter a missing portal vein, the smaller vessels around the portal vein take over the blood supply and direct blood flow to the liver in most cases, however there are several complications that can occur from the engorgement of blood to these same vessels. (portal-hypertension.com)
  • These complications result from portal hypertension and/or from liver insufficiency. (vivu.tv)
  • Women with Budd Chiari Syndrome (BCS) and/or portal hypertension are at high risk of pregnancy complications and adverse outcomes. (isth.org)
Cirrhotic7
  • Since cirrhotic patients with severe thrombocytopenia are at greater risk for bleeding, treatments against HCC such as liver transplantation, resection, local ablation therapy, and transarterial chemoembolization (TACE) can be performed following a platelet transfusion in those patients. (hindawi.com)
  • Moreover, a key pathogenic factor in the decline in status of PPH patients related to this shunting is the cirrhotic cardiomyopathy with myocardial thickening and diastolic dysfunction. (wikipedia.org)
  • Post-hoc analysis of a prospective cohort of 62 cirrhotic patients with newly US-detected nodule between 1-2 cm (study group). (radioloncol.com)
  • We analyzed real-life data of cirrhotic patients undergoing elective EBL at two large Viennese centers between Q1/2000-Q1/2018. (springer.com)
  • Individualized treatment options for patients with non-cirrhotic and cirrhotic liver disease. (meduniwien.ac.at)
  • Agents which decrease gastric mucosal blood flow (GMBF) are postulated to have beneficial effects in arresting gastrointestinal bleeding in cirrhotic patients with portal hypertension. (ox.ac.uk)
  • In this placebo-controlled, double-blind, crossover study, 20 cirrhotic patients with PHG were randomly assigned to receive either somatostatin followed by placebo (Group A) or placebo followed by somatostatin (Group B). Wedged hepatic venous pressure was monitored. (ox.ac.uk)
Variceal5
  • Common signs and symptoms may stem from decreased hepatic synthetic function (eg, coagulopathy), portal hypertension (eg, variceal bleeding), or decreased detoxification capabilities of the liver (eg, hepatic encephalopathy). (medscape.com)
  • Prophylactic endoscopic band ligation (EBL) is used to prevent variceal bleeding in patients with liver cirrhosis. (springer.com)
  • Transfusion with packed red blood cells (RBCs) and fresh frozen plasma (FFP) are usually required in patients with massive variceal bleeding. (medscape.com)
  • 1 These sequelae, variceal bleeding and refractory ascites, are associated with poor patient prognosis. (emjreviews.com)
  • Background: Hepatoportal sclerosis (HPS) is a cause of noncirrhotic portal hypertension, with patients typically presenting with variceal bleeding. (vivu.tv)
Retrospective2
  • Methods We performed a retrospective observational study of all HLTs performed in Spain (performed in 2 centers) from 1990 to 2020. (unican.es)
  • A retrospective chart review of patients presenting with SSNHL at Vancouver general hospital from 2015 to 2017 was also performed. (ubc.ca)
Diagnosis9
  • Hypersplenism secondary to portal hypertension (cirrhosis) was the second most common diagnosis (n = 19). (unboundmedicine.com)
  • In general, PPH is diagnosed 4-7 years after the patient is diagnosed with portal hypertension and in roughly 65% of cases, the diagnosis is actually made at the time of invasive hemodynamic monitoring following anesthesia induction prior to liver transplantation. (wikipedia.org)
  • In 41 patients (66.1%) the final diagnosis was HCC. (radioloncol.com)
  • Results: Among 160 patients with IPH in 1999 and 85 in 2005, 10% had aggravated disease at a mean of 6-7years after the diagnosis. (elsevierpure.com)
  • Patients with liver failure at diagnosis would be at high risk for subsequent disease aggravation. (elsevierpure.com)
  • Clinical diagnosis of NAFLD is difficult as most of the patients are asymptomatic. (nepjol.info)
  • Additionally, the percentage to improve the diagnosis and control of HTN among their of adult patients diagnosed with HTN increased from 16% patient population. (cdc.gov)
  • When patient charts did not show blood pressure diagnosis of HTN. (cdc.gov)
  • For patients with prior chronic organ insufficiency (SOFA score should be based on baseline): SOFA increased by = 2 points between 48 hours and 24 hours after diagnosis of infection. (who.int)
Ascites4
Cystic fibrosis11
  • Approximately 85-90% of patients with cystic fibrosis (CF) suffer from pancreatic insufficiency (PI), which predisposes them to malabsorption of lipids and lipid soluble vitamins leading to a deficiency of nonenzymatic antioxidants [ 2 ]. (hindawi.com)
  • However, the contribution of this cytokine to organ fibrosis in patients with cystic fibrosis is presently unclear. (bmj.com)
  • METHODS Polymorphisms in the TGF-β 1 gene defining amino acids of codons 10 and 25 were determined by ARMS-PCR using DNA stored on 171 Caucasian patients who were homozygous for the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. (bmj.com)
  • RESULTS Patients with cystic fibrosis of a TGF-β 1 high producer genotype for codon 10 had more rapid deterioration in lung function than those with a TGF-β 1 low producer genotype. (bmj.com)
  • Despite advances in the medical management of cystic fibrosis over the last three decades, there are still a number of unexplained differences in its clinical course, especially in the rate of development of respiratory failure of patients who appear to have the same CFTR genotype, degree of bacterial colonisation, and compliance with medication. (bmj.com)
  • Examination of lung tissue in two patients with cystic fibrosis showed strong immunohistological staining of inflammatory tissue using an antibody against this cytokine. (bmj.com)
  • The aim of this study is to determine the association between severity of liver disease and survival in patients with cystic fibrosis. (pucrs.br)
  • Patients at the Queensland Children's Hospital Cystic Fibrosis Service (Brisbane, Australia) were evaluated in a 27-year clinical cohort study. (pucrs.br)
  • Cystic fibrosis patients under 19 years of age were followed until the occurrence of liver transplantation, death, or end of follow-up. (pucrs.br)
  • A directed acyclic graph was used to assess possible predictors of survival in cystic fibrosis patients. (pucrs.br)
  • The study shows evidence that severe CFLD may be associated with an increased risk of death in patients with cystic fibrosis when adjusted for sex, diabetes and ursodeoxycholic acid therapy. (pucrs.br)
Hypertensive3
  • Somatostatin reduces gastric mucosal blood flow in patients with portal hypertensive gastropathy: a randomized, double-blind crossover study. (ox.ac.uk)
  • Our objective was to test the hypothesis that in a dose that significantly lowers wedged hepatic venous pressure (WHVP), a bolus injection of somatostatin will significantly decrease GMBF in patients with portal hypertensive gastropathy (PHG). (ox.ac.uk)
  • Socioeconomic variables identified as potential social determinants of alization for hypertensive disease (hypertension, hypertensive health contextualize COVID-19 health disparities by race and ethnicity. (cdc.gov)
Clinical10
  • We recorded the demographic and clinical characteristics of patients before TIPS. (researchsquare.com)
  • Here we provide a detailed protocol describing the clinical procedure of hepatic venous pressure gradient (HVPG) measurement in patients with advanced chronic liver disease followed by an instruction for transjugular biopsy. (jove.com)
  • Less is known about the clinical characteristics and natural history of HEV-4 than HEV genotype 3 infections in immunocompromised patients. (cdc.gov)
  • We retrieved patient identifiers for the organ donor and recipients from the organ donor registry and retrieved clinical details for donor and recipients from the electronic patient record. (cdc.gov)
  • Clinical information on the patients was obtained from medical records. (bmj.com)
  • We assessed the clinical resource use, staff time, relative service efficiency and overall societal costs associated with integrating HIV, diabetes and hypertension services in single one-stop clinics where persons with one or more of these conditions were managed. (uea.ac.uk)
  • A total of 34 pSS-PAH patients were recruited based on a clinical registry in Peking Union Medical College Hospital (PUMCH) between April 2019 and July 2021, a national referral center for CTD-PAH patients. (biomedcentral.com)
  • for example, in high-risk patients TIPS may offer clinical benefits when performed early in the disease course. (emjreviews.com)
  • Despite the high numbers of patients diagnosed worldwide, HCC continues to pose challenging clinical problems. (scirp.org)
  • We compared comorbidities, clinical features and other predictive factors between COVID-19 patients requiring ICU admission for intubation/mechanical ventilation and all other COVID-19 cases in Selangor, Malaysia. (who.int)
Acute liver f1
Outcomes8
  • There were no studies that included patients with virologic cure prior to kidney transplant that reported post-kidney transplant outcomes. (wjgnet.com)
  • In response, we conducted an investigation to 1) identify other infected recipients from the same donor, 2) confirm that the infection was indeed donor derived, 3) investigate the natural history of HEV-4 infection, and 4) study outcomes of infected patients who received ribavirin. (cdc.gov)
  • ObjectiveThe purpose of this study is to evaluate the effectiveness of oral, intratympanic steroid (IT) and Hyperbaric Oxygen therapy (HBOT) based treatments on hearing outcomes in patients with Sudden sensorineural hearing loss (SSNHL). (ubc.ca)
  • To evaluate management and outcomes of pregnancies in women with BCS and/or portal hypertension. (isth.org)
  • Women with confirmed BCS and/or portal hypertension who conceived at least once were enrolled and study outcomes were assessed up to 12 weeks after delivery or 6 weeks after pregnancy loss. (isth.org)
  • Adverse pregnancy outcomes in women with BCS and portal hypertension are common. (isth.org)
  • Hamulyák EN, Wiegers HMG, van Duuren JR, Middeldorp S, Ganzevoort W. Pregnancy Outcomes in Women with Budd Chiari Syndrome or Portal Hypertension [abstract]. (isth.org)
  • Methods: Treatment outcomes were evaluated in 50 patients who had a total of 125 BT for treatment of 93 nodules. (elsevierpure.com)
Transjugular2
  • During angiography, a catheter is placed selectively via either the transjugular or transfemoral route into the hepatic vein to measure portal pressure. (medscape.com)
  • Background: One of the most significant developments in recent years relating to the treatment of bleeding varicose veins of the esophagus and stomach (VVES) at Portal hypertension (PH), is the introduction into practice of the new endovascular technique - transjugular intrahepatic porto-systemic shunt (TIPS). (journalcra.com)
Control Hypertension1
  • To develop a support environment, to raise awareness and make behaviour changes for each citizen so that they would reduce salt intake in their daily diet to prevent and control hypertension, stroke and cardiovascular diseases and other non- communicable diseases, contributing to people's health protection, care and promotion. (who.int)
Prognosis1
Biliary obstruction2
  • [ 24 ] Ultrasonography of the upper abdomen may be indicated in patients with esophageal varices, especially if biliary obstruction or liver cancer is suspected. (medscape.com)
  • Symptoms of local recurrence include pain, bowel obstruction, portal hypertension, biliary obstruction, and malnutrition, which severely affect patients' quality of life ( 7 ). (frontiersin.org)
Severe11
  • PSE with selective TACE made it possible for patients with HCC and severe thrombocytopenia to receive systemic chemotherapy. (hindawi.com)
  • Therefore, there have been minimal differences in treatment strategy between patients with or without severe thrombocytopenia. (hindawi.com)
  • These findings indicate that a new strategy to treat patients with advanced HCC and severe thrombocytopenia is needed. (hindawi.com)
  • The aim of this study was to assess the safety and effectiveness of PSE with TACE for patients with HCC and severe thrombocytopenia. (hindawi.com)
  • The symptoms of hepatic encephalopathy may range from mild to severe and may be observed in as many as 70% of patients with cirrhosis. (medscape.com)
  • in the liver graft recipient, disease was severe and with progressive portal hypertension. (cdc.gov)
  • Pregnant wild type and IL-10-/- mice were injected with either normotensive or severe preeclamptic patient sera (sPE) during gestation. (bvsalud.org)
  • Severe CFLD was established by the presence of cirrhosis, portal hypertension, or esophageal varices. (pucrs.br)
  • Children who have sustained electri-cal injury relates to parental use of proton pump inhibitor for weeks adults or in patients with moderate to severe. (albionfoundation.org)
  • Nine patients were assigned to Group A, and 11 to Group B. Mild PHG was seen in 16 patients, and severe PHG in 4 patients. (ox.ac.uk)
  • Liver transplantation is generally considered a first choice for patients with early-stage HCC and moderate-severe cirrhosis (Child-Pugh class B and C), and to patients with unresectable disease. (medscape.com)
Esophageal3
  • it occurs in 80-90% of patients and gives rise to lower esophageal and gastric varices. (medscape.com)
  • Hematemesis resulting from bleeding esophageal varices is the most common presentation in patients with portal hypertension, although some patients seek medical help because of decompensated liver disease. (medscape.com)
  • Patients undergoing endoscopic band ligation (EBL) for esophageal varices (EV) were included between January 2000 and May 2020. (springer.com)
Obstruction3
Severity4
  • The nutritional status of CF patients is recognized as strong predictor of the severity of CF lung disease. (hindawi.com)
  • Importantly, hepatic venous pressure gradient (HVPG) will be measured in all patients that ensuring a comprehensive and reliable characterization of the severity of portal hypertension at the time of hormone level assessment. (meduniwien.ac.at)
  • It was observed that there was a significant decrease in portal vein velocity and its pulsatility index, a decrease in hepatic artery resistive index and pulsatility index, a reduction of hepatic vein phasicity, an increase in liver size and portal vein diameter with increasing severity of fatty liver. (nepjol.info)
  • Important patient factors to consider before performing TIPS include cardiac and renal function, severity of liver dysfunction, history of hepatic encephalopathy, and inflammatory status. (emjreviews.com)
Hepatic encephalopathy3
Angiography4
CSPH6
  • In patients with known cirrhosis, Doppler ultrasound has a specificity greater than 80% for CSPH. (medscape.com)
  • Nineteen patients (30.6%) did not have CSPH. (radioloncol.com)
  • All indices were significantly higher in the control group, indicating a more intense HBP liver signal intensity compared to patients with cirrhosis, even if the comparison was restricted to patients with no CSPH. (radioloncol.com)
  • Liver uptake of Gd-EOB-DTPA at the HBP is decreased in cirrhosis even if the liver function is minimally impaired and it falls down significantly in patients with CSPH compromising the recognition of hypointense lesions. (radioloncol.com)
  • This fact may represent a limitation for the detection of small HCC in patients with cirrhosis and CSPH. (radioloncol.com)
  • An HVPG of ≥6 mm Hg to 9 mm Hg indicates elevated portal pressure ('subclinical portal hypertension'), while an HVPG ≥10 mm Hg defines CSPH. (jove.com)
Shunts3
  • The present status of shunts for portal hypertension in cirrhosis. (jameslindlibrary.org)
  • 2008) Staging of portal hypertension and portosystemic shunts using dynamic nuclear medicine investigations. (scirp.org)
  • In 5 (8.0%) patients revealed thrombosis of intrahepatic stent and in 57 (89.2%) - portosystemic shunts were passable. (journalcra.com)
Recurrent4
  • Patients with locoregional recurrent pancreatic cancer after surgery treated with SBRT in our institution were retrospectively investigated from January 2010 to January 2020. (frontiersin.org)
  • Aim: To study evaluation efficacy of the treatment of patients after TIPS with recurrent bleeding from VVES when endoscopic intervention were unsuccessful. (journalcra.com)
  • Recurrent bleeding from VVES noted in 3 (4.8%) patients, which was the cause of death in one case. (journalcra.com)
  • Conclusion: We concluded that the main method of stop recurrent bleeding from VVES in patients with portal hypertension is TIPS. (journalcra.com)
Cardiovascular10
  • The goal of this project is to thoroughly investigate the dysregulation of hormonal systems in patients with ACLD, including cardiovascular hormones like classical and non-classical pathways of the reninangiotensin-aldosterone-system (RAAS), brain-type natriuretic peptide (BNP) and arginine-vasopressin (AVP), as well as the hypothalamic-pituitary-adrenal (HPA) axis. (meduniwien.ac.at)
  • To explore whether long‐term intervention with dietary nitrate ((NO3‐), a potential tolerance‐free source of beneficial vasoactive nitric oxide) and spironolactone (to oppose aldosterone's potential deleterious cardiovascular effects) improve cardiac structure/function, independent of blood pressure (BP), in patients with/at risk of type 2 diabetes (a population at risk of heart failure). (kcl.ac.uk)
  • High blood pressure, also known as hypertension (HTN), is a and rehabilitation facility in addition to the medical practice modifiable risk factor for cardiovascular disease, stroke, and known as BMG. (cdc.gov)
  • Hypertension is a preventable risk factor for cardiovascular disease, the leading cause of death globally. (edu.au)
  • When hypertension is present with tobacco smoking, poor nutrition, physical inactivity or excessive alcohol consumption, risk of cardiovascular disease is increased. (edu.au)
  • This study will test the effectiveness of a nurse-led intervention to reduce blood pressure in adults with hypertension and high cardiovascular risk. (edu.au)
  • Adults with hypertension and high cardiovascular risk will be identified through an audit of electronic medical records and invited to attend an assessment visit. (edu.au)
  • 1. Excessive salt consumption is the risk factor causing hypertension, stroke, cardiovascular diseases and other non-communicable diseases. (who.int)
  • More than 90% of people detected of contracting hypertension, cardiovascular diseases and other related diseases are counseled and instructed on adopting the low- salt diet. (who.int)
  • 90% of relevant health workers in medical care facilities are fully competent and perform counseling and instructions on low-salt diets in management and treatment of patients of hypertension, cardiovascular, diabetes and other related diseases. (who.int)
Progression4
  • Dysbalance of hormonal homeostasis is critically involved in development and progression of portal hypertension (PH) and may also influence liver fibrosis. (meduniwien.ac.at)
  • Further work is required to determine whether inhibition of TGF-β 1 activity in these patients may slow disease progression. (bmj.com)
  • This study showed that SBRT can significantly reduce pain, effectively control local tumor progression, and have acceptable toxicity for patients with locoregional recurrence after radical resection of primary pancreatic cancer. (frontiersin.org)
  • A variety of bridging therapies (BT) have been used to halt tumor progression in patients on the OLT waiting list. (elsevierpure.com)
Prehepatic1
Diabetes6
  • A total of 26 healths professionals participated in evaluating 253 recommended links for a total of 53 videos about general health, hypertension, or diabetes. (biomedcentral.com)
  • Methods: 2273 participants living with HIV infection, diabetes, or hypertension or combinations of these conditions were enrolled in 10 primary health facilities in Tanzania and Uganda and followed-up for up to 12 months. (uea.ac.uk)
  • The mean service costs per month of managing two conditions in a single participant were $39.11 (95% CI 33.99, 44.33), $32.18 (95% CI 30.35, 34.07) and $22.65 (95% CI 21.86, 23.43) for the combinations of HIV and diabetes and of HIV and hypertension, diabetes and hypertension, respectively. (uea.ac.uk)
  • Conclusion: Integration of HIV services with diabetes and hypertension control reduces both health service and household costs, substantially. (uea.ac.uk)
  • Effective treatment algorithms are needed to guide diabetes care at hospital discharge in general medicine and surgery patients with type 2 diabetes. (diabetesjournals.org)
  • Measurement of HbA 1c on admission is beneficial in tailoring treatment regimens at discharge in general medicine and surgery patients with type 2 diabetes. (diabetesjournals.org)
Mortality4
  • An HVPG ≥16 mm Hg is associated with higher mortality in patients with compensated and decompensated cirrhosis. (medscape.com)
  • Mortality from progressing PN observed in 2 patients. (journalcra.com)
  • High mortality after implementation of public emergency operations at an altitude of bleeding stresses the need for the introduction of TIPS in the minutes introducing patients to emergency surgery. (journalcra.com)
  • However, in our small cohort, the chance of term live birth of 56% seems too high and maternal mortality too low to consider BCS or portal hypertension an absolute contra-indication. (isth.org)
Comorbidities3
  • For patients with early-stage (non-metastasized) HCC, a partial hepatectomy can offer a potential cure, provided the patient is a surgical candidate, based on performance status, comorbidities, and certain disease characteristics. (medscape.com)
  • For patients with unresectable disease who are not surgical candidates because of their performance status, comorbidities, or failure to meet UNOS criteria, National Comprehensive Cancer Network (NCCN) guidelines recommend offering locoregional therapies before initiating systemic treatment. (medscape.com)
  • Methods: Field data collected during the COVID-19 outbreak in Selangor, Malaysia, up to 13 April 2020 were used, comprising socio-demographic characteristics, comorbidities and presenting symptoms of COVID-19 cases. (who.int)
Ultrasound2
  • In portal hypertension imaging, ultrasound techniques such as duplex ultrasonography or spectral Doppler imaging and color Doppler imaging or power Doppler imaging are the modalities of choice, because they are noninvasive, rapid, and highly sensitive and specific. (medscape.com)
  • A total of 70 patients were included in this study with focal lesions on ultrasound are included while pregnant patients are excluded. (scirp.org)
Hemodynamic1
  • It is inferred that apart from assessing the hemodynamic changes in the portal circulation, we can also predict early portal hypertension and hepatic fibrosis. (nepjol.info)
Conclusion2
  • CONCLUSION: These results indicate ACE overexpression in the urine of preeclamptic patients and suggest that it may be a new marker for the disease. (bvsalud.org)
  • Conclusion: The COVID-19 cases in Selangor, Malaysia requiring intubation/mechanical ventilation were significantly older, with a higher proportion of hypertension and symptoms of fever, dyspnoea and lethargy. (who.int)
Occur2
  • Heat cramps are characterized by daynight reversal, asterixis, tremor, dysarthria, delirium, drowsiness and coma may occur in the crit-ically ill patient. (albionfoundation.org)
  • Can portal hypertension occur without cirrhosis? (vivu.tv)
20211
  • Thirty-four unrelated patients with pSS-PAH were recruited from April 2019 to July 2021 at Peking Union Medical College Hospital. (biomedcentral.com)
Workup1
  • Electroencephalography may be helpful in the initial workup of a patient with cirrhosis and altered mental status, when ruling out seizure activity may be necessary. (medscape.com)
Secondary3
  • A considerable number of patients with HCC have thrombocytopenia secondary to hypersplenism. (hindawi.com)
  • Zone 3 necrosis can be observed in portal hypertension secondary to congestive heart failure and Budd-Chiari syndrome. (medscape.com)
  • Our aim was to identify plasma ECM proteins associated to end-stage HF and secondary PH in relation to haemodynamics, before and after heart transplantation (HT).METHODS AND RESULTS: Twenty ECM plasma proteins were analysed with proximity extension assay in 20 controls and 26 HF patients pre-HT and 1 year post-HT. (lu.se)
Asymptomatic2
  • Some patients with cirrhosis are completely asymptomatic and have a reasonably normal life expectancy. (medscape.com)
  • Patients may be asymptomatic or have nonspecific manifestations such as fatigue and malaise. (msdmanuals.com)
Liver transplantation2
Survival12
  • The aim of this study was to compare the post-TIPS survival between patients with PA-HSOS and those with other etiologies of hepatic portal hypertension. (researchsquare.com)
  • After PSM, OLT-free survival was significantly better in PA-HSOS patients than in patients with viral hepatitis ( P = 0.0011), primary biliary cirrhosis or autoimmune hepatitis ( P = 0.021), and schistosomiasis ( P = 0.025). (researchsquare.com)
  • The literature currently provides no data comparing the long-term survival of PA-HSOS patients with that of patients with other etiologies of portal hypertension after TIPS treatment. (researchsquare.com)
  • Sorafenib has shown survival benefit in patients with advanced HCC patients [ 1 , 2 ]. (hindawi.com)
  • The 5 year patient survival of kidney transplant recipients with and without hepatitis C cirrhosis ranged from 31% to 90% and 85% to 92%, respectively. (wjgnet.com)
  • Hepatitis C kidney transplant recipients had lower 10-year survival when compared to hepatitis B patients, 40% and 90% respectively. (wjgnet.com)
  • There were no studies of direct acting antiviral therapy and effect on patient or graft survival after kidney transplantation. (wjgnet.com)
  • However, the impact of CFLD on patient survival remains to be further studied. (pucrs.br)
  • Even after radical resection, most patients will still have local and/or metastatic recurrence within 2 years ( 3 , 4 ), and the 5-year survival rate is only 20-25% ( 5 ). (frontiersin.org)
  • SBRT combined with chemotherapy for the treatment of locally advanced pancreatic cancer can effectively control local tumors and alleviate local symptoms, prolong the overall survival of patients, and has tolerable toxicity ( 16 - 19 ). (frontiersin.org)
  • The survival of both stages is markedly different with compensated patients having a median survival time of over 12 years compared to decompensated patients who survive less than 2 years (1, 3). (vivu.tv)
  • Adjuvant transarterial thromboembolization (TACE) has shown to increase overall survival in patient with microvascular invasion-HCC with tumor size ≥ 5 cm or multinodular tumors. (medscape.com)
Infection1
  • This study highlights the role of organ donation in HEV transmission, provides additional data on the natural history of HEV-4 infection, and points out differences between genotype 3 and 4 infections in immunocompromised patients. (cdc.gov)
Underwent3
  • Twenty patients (eight child class A and 12 class B patients) underwent a liver vein catheterization with determination of splanchnic and systemic haemodynamics. (unboundmedicine.com)
  • Results: In 58 patients underwent TIPS observations using bare metal stents and 7 cases -stent grafts. (journalcra.com)
  • Patients underwent a mean of 2.5 BTs. (elsevierpure.com)
Chronic Liver D2
  • While many studies have investigated the levels of different hormones in patients with advanced chronic liver disease (ACLD), there have not yet been more comprehensive studies, investigating patterns of hormonal dysregulation in different stages of PH and ACLD. (meduniwien.ac.at)
  • In patients with chronic liver disease that would require major resection, consider preoperative portal vein embolization. (medscape.com)
Venous system1
  • Portal hypertension is defined by a pathologic increase in the pressure of the portal venous system. (vivu.tv)
Hepatocellular2
  • Thrombocytopenia often makes the introduction of systemic treatment difficult in patients with cirrhosis and hepatocellular carcinoma (HCC). (hindawi.com)
  • Hepatocellular carcinoma (HCC) frequently develops in patients with cirrhosis. (hindawi.com)
SYSTEMATIC REVIEW2
  • We conducted a systematic review of kidney only transplant in patients with hepatitis C and advanced fibrosis. (wjgnet.com)
  • Methods A systematic review of primary studies published in the English language between January 2000 to June 2018 identified by searching Medline, PubMed, Web of Science, and Embase databases was performed. (ubc.ca)
Doppler4
  • To assess the role of Doppler ultrasonography of the splenoportal system in NAFLD patients. (nepjol.info)
  • Then, Doppler Ultrasonography examination of the abdomen of the selected patient was done and assessed for different parameters. (nepjol.info)
  • Doppler ultrasonography of the splenoportal system can be used to predict early fibrosis, portal hypertension, and thus cirrhosis. (nepjol.info)
  • After evaluating by Doppler sonography and doing core biopsy, the patients were sent to the Department of Pathology, Mayo Hospital for histopathological examination. (scirp.org)
Treatment8
  • Treatment of the sequelae of portal hypertension can be achieved through endovascular management by referral to an interventional radiologist on an outpatient or emergent basis as required. (medscape.com)
  • Inclusion criteria were Primary articles on the treatment with (oral, IT steroid and HBOT) of patients diagnosed as having SSNHL. (ubc.ca)
  • While current treatment methods focus on medication and funding from Montana's Community Transformation Grant lifestyle modifications, other effective care options have for an HTN quality improvement project. (cdc.gov)
  • Materials and Methods: Analyzed the results of examination and treatment of 76 patients undergoing TIPS attempt was made. (journalcra.com)
  • Moreover, TIPS is a type of porto-systemic shunt and cannot be considered a definitive treatment for patients with liver cirrhosis complicated with portal hypertension. (journalcra.com)
  • This underscores the need for aggressive treatment of patients who otherwise may not be eligible for OLT. (elsevierpure.com)
  • this may include patients who are not candidates for locoregional therapies and/or those in whom local treatment has failed. (medscape.com)
  • Placebo control group:Matched placebo (saline) is administered using the exact same injection method and timing as the standard treatment plus an equal amount of saline placebo. (who.int)
HVPG1
Heart failure2
  • Patients tend to have a poor cardiac status, with 60% having stage III-IV NYHA heart failure. (wikipedia.org)
  • If a patient with heart failure nevertheless and respond to medical care to the height spurt, the first - hour collections, probably because their muscles tire during the paroxysmal stage. (albionfoundation.org)
Hypersplenism1
Endoscopy2
  • GI) endoscopy in the 1970s and the subse- data Indications for the procedure and en- quent development of smaller instruments doscopic findings were recorded. (who.int)
  • At least 2 endoscopy nurses were present in the endoscopy room to assist with Methods the procedure. (who.int)