• Although minimally invasive techniques are widely used for the surgical management of uterine leiomyoma, there is significant controversy regarding the use of morcellation to remove bulky tumors laparoscopically. (prweb.com)
  • Leiomyoma is very rare, accounting for less than 1% of esophageal tumors. (stelizabeth.com)
  • Uterine leiomyomas are the most common solid tumors in the female reproductive tract, occurring in 20% to 40% of women in the reproductive age. (sls.org)
  • Cutaneous leiomyomas are benign (not cancer) tumors that form in the muscle tissue around a hair follicle. (cancer.gov)
  • Previously, these tumors were classified as GI leiomyomas, leiomyosarcomas, leiomyoblastomas, or schwannomas, on the basis of histologic findings and the fact that these tumors apparently originate in the muscularis propria layer of the intestinal wall. (medscape.com)
  • Further analyses seek to define the Wnt signaling mechanisms and are focused on our lab's unique organotypic model of leiomyoma, in which human fibroid tumors are grown in immune-compromised mice. (tufts.edu)
  • Several studies show that EGCG in the diet increased cell death (apoptosis) of leiomyoma (fibroid tumors), reduced the number of tumors, and reduced the size of tumors. (green-tea-health-news.com)
  • Another green tea uterine fibroids study showed significant decreases in proliferation cell nuclear antigen (PCNA) and cyclin-dependent kinase 4 (Cdk4) for tumors reduced in volume and weight (Zhang D et al, Green tea extract inhibits proliferation of unterine leiomyoma cells in vitro and in nude mice, American Journal Obstet Gynecol, March 2010). (green-tea-health-news.com)
  • It is thought that leiomyoma is the result of either transformation of normal uterine muscle cells into abnormal cells through somatic mutations , or through the growth of abnormal uterine muscle cells into tumors. (wikidoc.org)
  • Leiomyomas are the most common benign uterine tumors. (casereports.in)
  • Leiomyomas are the commonest benign tumors of the uterus. (casereports.in)
  • Leiomyomas are benign tumors of myometrium. (jpgo.org)
  • Leiomyomas of the urterus (or uterine fibroids) are benign tumors that arise from the overgrowth of smooth muscle and connective tissue in the uterus. (medscape.com)
  • Leiomyoma, the commonest benign tumor of the uterus is a rare occurrence in the oral cavity and when present mimics various other soft tissue tumors of the oral cavity and lead to a diagnostic dilemma to the clinician. (bvsalud.org)
  • Leiomyomas are benign smooth muscle tumors that are relatively common, especially in the uterus (about 95%) followed by the gastrointestinal tract and skin 2 . (bvsalud.org)
  • Mason s trichrome and Van Geison s stains are specific for muscle cells and collagen fibers whereas Mallory s Phosphotungstic Acid (PTAH) and positive IHC marker desmin may aid to differentiate leiomyoma from other spindle cell tumors such as myofibroblastoma 4 . (bvsalud.org)
  • Leiomyomas or uterine fibroids are benign tumors of the uterus that consist of smooth muscle and extracellular matrix collagen and elastin. (mims.com)
  • Cervical leiomyomas are benign smooth-muscle tumors. (msdmanuals.com)
  • Uterine Fibroids Uterine fibroids (leiomyomas) are benign smooth muscle tumors of the uterus. (msdmanuals.com)
  • Vaginal leiomyomas are rare solid tumors which occur in middle aged females aged across 35 to 50 years of age. (medimagingcasereports.com)
  • Although leiomyoma is the most common benign esophageal tumor, malignant carcinoma is still 50 times more likely. (wikipedia.org)
  • A leiomyoma is a benign tumor made up mostly of smooth muscle cells. (medlineplus.gov)
  • It is called an intestinal leiomyoma when the tumor is located in the intestinal tract. (medlineplus.gov)
  • A leiomyoma is a relatively harmless and non-spreading tumor that arises from the smooth muscle of the stomach and intestinal tract. (petmd.com)
  • A leiomyoma is a benign, smooth muscle tumor. (stelizabeth.com)
  • A leiomyoma is generally a benign tumor that arises from the smooth muscle of esophagus. (stelizabeth.com)
  • Leiomyoma is a benign tumor with smooth muscle origin, low frequency in domestic animals, and like the others neoplasias, rarely described in wild felids. (vin.com)
  • The results of the alpha smooth muscle and the muscular actin antibodies characterized the tumor as a leiomyoma. (vin.com)
  • Gastric gastrointestinal stromal tumor (GIST) en face. (medscape.com)
  • Abstract: Uterine leiomyoma, frequently known as fibroid, is a benign smooth muscle tumor that occurs in women between the ages of 30-55 years old. (tufts.edu)
  • Palabras clave: Leiomioma Leiomioma de prĂ³stata Tumor benigno de prĂ³stata Abstract We present a case of pure prostatic leiomyoma, benign and rare entity, diagnosed in a patient with prostatism. (symptoma.com)
  • Leiomyoma is a benign tumor and has excellent prognosis when complete resection is applied and atypia is not detected.4 On our case, no atypia was reported related with the prostatic leiomyoma. (symptoma.com)
  • Review of the pathophysiology , diagnosis, and therapy of vulvar leiomyoma, a rare gynecological tumor. (symptoma.com)
  • Leiomyoma is the most common tumor of the uterus and female pelvis. (jpgo.org)
  • Histopathological examination of the tumor removed confirmed the diagnosis of a leiomyoma. (jpgo.org)
  • DISCUSSION Leiomyoma is a tumor of smooth muscle cells. (scarscenter.com)
  • Leiomyoma is the most common pelvic tumor of the uterus. (jpgo.org)
  • Fine needle aspiration (FNA) of the tumor showed a spindle cell tumor consistent with a leiomyoma. (figshare.com)
  • Metastatic leiomyoma are an extremely rare complication after surgery to remove the uterus for uterine fibroids. (wikipedia.org)
  • In this puma, it was diagnosed the presence of leiomyoma in the uterus wall. (vin.com)
  • There was not found any report of uterus leiomyoma in big cats in captivity in Brazil, only the report of a leiomyosarcoma in mammary gland with metastasis in multiple organs in a captive jaguar ( Panthera onca ). (vin.com)
  • Diagnosis of pedunculated leiomyoma can be established by ultrasound which shows palpable mass separate from uterus and ovaries. (casereports.in)
  • Pedunculated leiomyomas of the uterus are not uncommon. (casereports.in)
  • If a pelvic mass is palpable separate from the uterus and ovaries then ultrasound diagnoses of pedunculated leiomyoma can be established. (casereports.in)
  • However, parasitic leiomyomas of the uterus have been described only rarely in the ultrasonographic literature [ 3 - 5 ]. (casereports.in)
  • A computed tomography of the abdomen and pelvis showed the presence of multiple leiomyomas in the uterine fundus and body of the uterus, ranging in size from 8.3 to 11 cm (figure 1). (jpgo.org)
  • The leiomyoma was found to be passing to the right side of the uterus behind the cervix, and inferiorly. (jpgo.org)
  • CT scan of abdomen-pelvis -suggestive of multiple leiomyomas in the fundus and body of uterus. (jpgo.org)
  • Intraoperative findings: uterus yellow arrow, left fallopian tube (green arrow), and left ovary (white arrow) stretched over the large left broad ligament leiomyoma. (jpgo.org)
  • D25.2 is a valid billable ICD-10 diagnosis code for Subserosal leiomyoma of uterus . (icd10coded.com)
  • Angioleiomyoma is a relatively rare type of leiomyoma of the uterus that originates from smooth muscle cells and contains thickwalled vessels. (ejgo.net)
  • Associated with papillary variant of renal cell carcinoma and multiple cutaneous leiomyoma. (wikipedia.org)
  • The importance of correct diagnosis of cutaneous leiomyoma lies in the association of multiple cutaneous leiomyomas with uterine fibroids and papillary renal cell carcinoma in what is known as Reed syndrome, or hereditary leiomyomatosis and renal cell cancer (HLRCC), an autosomal dominant disorder. (medscape.com)
  • In the retrospective analysis, the research team examined the Mount Sinai Data Warehouse (MSDW) database, which includes data on more than 3 million patients, to identify a cohort of 2,075 women who had undergone myomectomy for presumed benign leiomyoma between 2005 and 2014. (prweb.com)
  • We additionally present a review of the literature on development of parasitic leiomyoma after myomectomy, summarizing 35 published cases in addition to our own. (sls.org)
  • Parasitic leiomyomas, Myomectomy, Uncontained morcellation. (sls.org)
  • Most symptomatic cervical leiomyomas are removed by myomectomy (particularly if childbearing capacity is important) or, if myomectomy is technically difficult, by hysterectomy. (msdmanuals.com)
  • Surgically remove symptomatic cervical leiomyomas, usually by myomectomy but, if myomectomy is not possible, by hysterectomy. (msdmanuals.com)
  • A subsequent U.S. Food and Drug Administration review found a higher prevalence of unsuspected uterine sarcoma and LMS among patients undergoing myomectomy or hysterectomy for presumed benign leiomyomas than was previously reported. (qxmd.com)
  • A pedunculated, subserosal uterine leiomyoma with extensive cystic degeneration can mimic an ovarian tumour on imaging and should be considered in the differential diagnosis of an adnexal mass. (annals.edu.sg)
  • Immunohistochemical evidence for leiomyogenic markers coupled with the low mitotic rate, the lack of an infiltrating growth pattern, and the indolent clinical course led to the diagnosis of atypical leiomyoma with prominent myxoid change. (bmj.com)
  • The patient underwent hysterectomy with a diagnosis of recurrent cotyledonoid dissecting leiomyoma. (istinye.edu.tr)
  • The aim of the present study is to report an unusual case of oral leiomyoma mimicking a gingival epulis and demonstrate the importance of the immunohistochemical results in determining the final diagnosis. (bvsalud.org)
  • These histomorphologic features and the IHC profile lead to the diagnosis of an oral leiomyoma. (bvsalud.org)
  • Diagnosis of cervical leiomyomas is by physical examination. (msdmanuals.com)
  • Uterine fibroids are leiomyomata of the uterine smooth muscle. (wikipedia.org)
  • Uterine leiomyomas (also called fibroids) may be assessed by Doppler ultrasonography assessment before uterine artery embolization. (medscape.com)
  • Cervical leiomyomas do not prolapse, but some submucosal fibroids prolapse through the cervical canal into the vagina. (msdmanuals.com)
  • Laparoscopic hysterectomy and excision of vaginal fibroid was performed to remove the vaginal fibroids and subsequent histopathology examination confirmed a vaginal leiomyoma. (medimagingcasereports.com)
  • Gastric leiomyoma is most common at the esophageal-gastric junction, where the esophagus meets the stomach cavity. (petmd.com)
  • In this video, we review a case of the complex endoscopic removal of a large esophageal leiomyoma by a submucosal resection technique extending into the mediastinum. (sages.org)
  • The patient is a healthy 38 year old woman with dysphagia, found to have a 2.5 by 4 centimeter mass in the mid esophagus consistent with a benign esophageal leiomyoma. (sages.org)
  • Lateral radiographic images of the thorax and cranial portion of the abdomen of a 10-year-old spayed female Rottweiler with a 2-month history of regurgitation and weight loss, despite no apparent changes in appetite, that was subsequently deemed to have esophageal leiomyoma. (avma.org)
  • A 27-year-old woman underwent a video-assisted thoracoscopic enucleation of a giant horseshoe esophageal leiomyoma. (figshare.com)
  • Ultrasonography showed a right broad ligament leiomyoma measuring 3.8x3.5 cm and a right ovarian simple cyst measuring 3.5x1.5 cm. (jpgo.org)
  • She followed up for surgery after 6 months, and a repeat scan done now showed an 8.5x9.1 cm sized right broad ligament leiomyoma with significant increase in size as compared to previous scan and a right ovarian simple cyst of 2.7x1.7 cm. (jpgo.org)
  • We report a case of a 30 year old woman with a 26 weeks' size broad ligament leiomyoma. (jpgo.org)
  • Cutaneous leiomyomas can develop wherever smooth muscles are present, but malignant transformation probably does not occur. (medscape.com)
  • If your leiomyoma is small and not expected to be malignant, you may be advised to take a wait and watch approach that includes regular barium swallows and endoscopy to help monitor your condition. (stelizabeth.com)
  • We report an unusual case of a large cystic, pedunculated uterine leiomyoma mimicking a primary malignant ovarian tumour on sonography and computed tomography (CT). (annals.edu.sg)
  • Rarely, uterine leiomyomas may undergo malignant degeneration to become a sarcoma. (medscape.com)
  • The true incidence of malignant transformation is difficult to determine, because leiomyomas are common, whereas malignant leiomyosarcomas are rare and can arise de novo. (medscape.com)
  • In this report, we discuss the aggressive clinical course of a patient with recurrent cotyledonoid dissecting leiomyoma resulting in hysterectomy, which has been reported in a limited number of studies in the literature. (istinye.edu.tr)
  • Surgical management of presumed benign uterine leiomyomas received popular media attention when a case of disseminated LMS occurred after laparoscopic power morcellator-assisted hysterectomy. (qxmd.com)
  • The broad ligament is the commonest extrauterine site for the occurance of a leiomyoma. (jpgo.org)
  • The broad ligament is the commonest extrauterine site for the occurrence of leiomyoma. (jpgo.org)
  • 1] Extrauterine leiomyomas may develop in the broad ligament or at other sites where smooth muscle exists. (jpgo.org)
  • Surgical excision or ablation of leiomyomas may be helpful for some symptomatic women. (medscape.com)
  • In addition, the risk-prediction model may play a role in shaping future surgical guidelines used in the management of leiomyoma. (prweb.com)
  • Surgical resection: removal or enucleation of the leiomyoma. (stelizabeth.com)
  • Transvaginal surgical enucleation of the vaginal leiomyoma is usually curative and recommended as the initial treatment of choice to prevent for dystocia. (hkmj.org)
  • 3] Broad ligament leiomyomas pose diagnostic and surgical difficulties. (jpgo.org)
  • Parasitic leiomyoma is estimated to occur after 0.20 to 1.25% of laparoscopic myomectomies, and is diverse in it's presenting symptoms and surgical findings. (sls.org)
  • 2 So far, the different variants include classic leiomyoma, 1, 2 leiomyoblastoma, 3 and vascular leiomyoma, 4 this last tumour being the most common histotype. (bmj.com)
  • The World Health Organization (WHO) distinguishes three types of leiomyomas: leiomyoma (solid), angiomyoma (vascular leiomyoma) and epitheloid leiomyoma (leioblastoma) 9 . (bvsalud.org)
  • Rarely, a parasitic leiomyoma may become torsive and cause an acute abdomen [ 3 ]. (casereports.in)
  • Parasitic leiomyoma is a rare condition that may be spontaneous or iatrogenic in origin. (sls.org)
  • Laparoscopic uterine surgery and tissue morcellation are procedures that may lead to the development of parasitic leiomyoma. (sls.org)
  • Treatment with relugolix combination for up to 52 weeks yields sustained reductions in heavy menstrual bleeding as well as subsequent increases in iron stores in women with uterine leiomyomas , as shown in a study. (mims.com)
  • OBJECTIVE: To evaluate the effects of transdermal hormone replacement therapy (HRT) on uterine and leiomyoma size and on uterine bleeding patterns in postmenopausal women with uterine leiomyomas. (uniroma1.it)
  • Seventy postmenopausal women with uterine leiomyomas were enrolled and treated for 12 cycles of 28 days each with transdermal 17 beta-estradiol (E(2)) patches plus oral medroxyprogesterone acetate continuously added (group A) or with calcium carbonate (group B). At entry and every three cycles, uterine and leiomyoma dimensions were measured by transvaginal ultrasonography. (uniroma1.it)
  • We hypothesize that a preexisting submucosal leiomyoma became colonized by neoplastic plasma cells with resultant expansion and protrusion of the leiomyoma through the cervical canal. (dtic.mil)
  • On speculum examination, sometimes a prolapsed submucosal leiomyoma is visible at or beyond the external cervical os. (msdmanuals.com)
  • A prolapsed submucosal leiomyoma may be friable and ulcerated. (msdmanuals.com)
  • Although suggestive of leiomyoma in the histopathologic exam, it was decided to do an immunohistochemistry to find the origin of the neoplastic cells. (vin.com)
  • Speculum exam revealed a mass protruding through the cervical canal highly suggestive of a prolapsed leiomyoma. (dtic.mil)
  • Histopathological examination revealed tumour composed of interlacing bundles of smooth muscles with oedematous intervening stroma suggestive of leiomyoma (Figure 1d). (ommegaonline.org)
  • Abdominopelvic ultrasonography showed a large heterogenous lesion of 20x18 cm in the uterine fundus, suggestive of a leiomyoma. (jpgo.org)
  • The pathogenesis of leiomyoma is characterized by benign smooth muscle neoplasm . (wikidoc.org)
  • Pathology showed atypical spindle cell neoplasm, favoring pleomorphic leiomyoma. (scarscenter.com)
  • The low incidence of this lesion, the unusual location, and its histomorphological pattern of presentation which needs to be differentiated from other spindle cell lesions posing a diagnostic challenge makes the report of this case worthy in a 32-year-old male, with a soft tissue swelling of the right lower gingiva which appeared to be an epulis but finally turned out to be a leiomyoma. (bvsalud.org)
  • Mesenchymal neoplasms of the gallbladder are rare and in particular leiomyomas of the gallbladder have been rarely reported, all of them in patients with immune system disorders. (wikipedia.org)
  • Cutaneous leiomyomas are benign soft-tissue neoplasms that arise from smooth muscle (arrector pili). (medscape.com)
  • In many cases, owing to their benign nature, even large leiomyomas with narrow margins can be removed successfully. (petmd.com)
  • large leiomyomas may partially block the urinary tract. (msdmanuals.com)
  • The measurement of hemoglobin and/or hematocrit levels might be considered in patients with multiple leiomyomas, because erythrocytosis is reported in rare cases. (medscape.com)
  • Two thousand one hundred twelve patients with symptomatic leiomyomata were eligible for long-term follow-up at 27 sites representing a geographically diverse set of practices, including academic centers, community hospitals, and closed-panel health maintenance organizations. (duke.edu)
  • Only one case of atypical leiomyoma has been described previously at this location, 5 although it did not display myxoid change. (bmj.com)
  • Myxoid degeneration of leiomyoma is one of the rarer types of degeneration that can occur in a uterine leiomyoma . (pacs.de)
  • This term is related but not identical to the term myxoid uterine leiomyoma . (pacs.de)
  • Subserosal leiomyomas may be beneath the uterine surface, exophytic or pedunculated. (casereports.in)
  • If pedunculated subserosal leiomyoma develops an extremely long tenuous stalk, it is called a wandering or migrating leiomyoma [ 1 ]. (casereports.in)
  • In 1809, the first laparotomy was conducted by Ephraim McDowell to treat leiomyoma in Danville, USA. (wikidoc.org)
  • During laparotomy, a large mesosalpingeal leiomyoma measuring 10x12 cm was found on the left side, with left utero-ovarian ligament stretched posteriorly and left fallopian tube stretched anteriorly over it (figure 1). (jpgo.org)
  • The purpose of this article is to provide background on the epidemiologic, clinical, and economic impact of uterine leiomyomas, summarize the concerns associated with treating women with potential occult leiomyosarcomas (LMSs), and review the known and emerging imaging features of typical and atypical leiomyomas and explain how to differentiate them from LMSs. (qxmd.com)
  • However, genital leiomyomas are usually asymptomatic solitary lesions arising from the dartoic, vulvar, or mammillary muscles in the genital region or on the nipple. (medscape.com)
  • This case highlights a rare presentation of an extraosseous plasmacytoma within the female genital tract and to our knowledge is the first reported case of a plasmacytoma involving a leiomyoma. (dtic.mil)
  • However, of a uterine leiomyoma with other genital blood tests on the woman were normal and organs unaffected. (who.int)
  • As other leiomyomata, they are benign, but may lead to excessive menstrual bleeding (menorrhagia), often cause anemia and may lead to infertility. (wikipedia.org)
  • Laboratory testing is generally not necessary for evaluation of leiomyomas unless there is abnormal vaginal bleeding or to rule out other conditions. (medscape.com)
  • Vaginal leiomyomas are rare benign solid tumours of the vagina. (hkmj.org)
  • Here we describe a patient with a vaginal leiomyoma diagnosed during the mid-trimester that could have caused dystocia. (hkmj.org)
  • Vaginal leiomyoma most commonly arises from the anterior vaginal wall. (medimagingcasereports.com)
  • Ultrasonography and magnetic resonance images (MRI) revealed multiple vaginal leiomyomas. (medimagingcasereports.com)
  • Rare Case of Vaginal Leiomyoma - A Case Report. (medimagingcasereports.com)
  • Leiomyomas are rare solid tumours of the ovary accounting for 0.5 - 1% of the benign ovarian tumours [1] . (ommegaonline.org)
  • Primary leiomyoma of the ovary (PLO) is rare with less than 100 cases reported in English literature [5,6] . (ommegaonline.org)
  • Stage of surgery almost near the point of removal of the leiomyoma: LO - left ovary, LUOL - left utero-ovarian ligament, L - leiomyoma, LFT - left fallopian tube. (jpgo.org)
  • Stage of surgery after removal of the leiomyoma: MS - mesosalpinx, LB - leiomyoma bed, LFT - left fallopian tube, LO - left ovary. (jpgo.org)
  • There is a marked decrease of CCN5 in uterine leiomyoma as compared to the normal myometrium from the same patient. (tufts.edu)
  • Our preliminary results using qRT-PCR in an analysis of patient matched uterine leiomyoma and myometrium show a decrease in both the HBP1 and CCN5 mRNAs. (tufts.edu)
  • Pelvic ultrasound revealed uterine enlargement, multiple small leiomyomas, and a large mass in the myometrium. (ejgo.net)
  • Durham, NC (PRWEB) March 12, 2015 -- In a study published in The Oncologist on March 12, 2015, researchers describe the development of a new model that predicts the risk of unexpected uterine sarcoma in women undergoing minimally invasive procedures for the removal of presumed benign leiomyoma. (prweb.com)
  • To help quantify this risk, a team of researchers led by Andrew S. Brohl, MD, at the Icahn School of Medicine at Mount Sinai in New York, NY, retrospectively evaluated the incidence of unexpected uterine sarcoma among women undergoing minimally invasive leiomyoma removal at Mount Sinai facilities since 2005. (prweb.com)
  • We are presenting a case of giant ovarian leiomyoma in a young lady which was suspected as germ cell tumour on imaging. (ommegaonline.org)
  • Patient was kept under observation for the left ovarian leiomyoma. (ommegaonline.org)
  • An incision was made parallel and above the left utero-ovarian ligament and the leiomyoma was enucleated avoiding injury to the fallopian tube. (jpgo.org)
  • True broad ligament leiomyomas arise from the muscle fibers normally found in the mesometrium, like the round ligament, utero-ovarian ligament and connective tissue surrounding the ovarian and the uterine vessels. (jpgo.org)
  • We studied a case of leiomyoma of the bladder floor in a woman with excretion urography, voiding cystourethrography, abdominal echography, computed tomography scan, and transvaginal echography. (karger.com)
  • Diagnose cervical leiomyomas by pelvic examination and sometimes transvaginal ultrasonography or MRI. (msdmanuals.com)
  • Transvaginal uterine artery ligation in a woman with uterine leiomyomas. (bvsalud.org)
  • Histology was that of a leiomyoma with extensive cystic degeneration. (annals.edu.sg)
  • On histopathological examination, a leiomyoma with cystic and hyaline degeneration was seen. (jpgo.org)
  • Microscopically, the benign leio- multiple calcified bilharzial ova myoma showed multiple epitheloid granu- lomas with calcified bilharzial ova within the leiomyoma. (who.int)
  • Figure 3 Two calcified bilharzial ova within the leiomyoma which, as in our case, be seen long after the original infection. (who.int)
  • Leiomyomas rarely cause symptoms when they are smaller than 5 cm. in diameter. (stelizabeth.com)
  • OBJECTIVE: Human chorionic gonadotropin (hCG) has proliferative effects on uterine smooth muscle and leiomyoma tissue in vitro. (rti.org)
  • Uterine leiomyoma is a collection of hyperplastic uterine smooth muscle, along with endothelial cells, fibroblast, collagen, and sulfate proteoglycan. (tufts.edu)
  • The symptoms for a 30-year-old male with a 10 cm leiomyoma included "dead leg" pains. (wikipedia.org)
  • Prostatic leiomyomas can present with voiding difficulties or obstructive symptoms 1. (symptoma.com)
  • Most cervical leiomyomas eventually cause symptoms. (msdmanuals.com)
  • The resultant granulomatous inflammation had possibly influenced the Figure 1 An epithelioid granuloma within the size of the fibroid, explaining its relatively leiomyoma large size in this patient. (who.int)