Lassa virus. Medical search. Frequent questions

Serological and immunochemical investigations suggest the existence of both common and unique antigenic determinants on the viruses from Mozambique, -Zimbabwe and West Africa. (bl.uk)
Lassa - West Africa and Mopeia -southeast Africa. (bl.uk)
The Lassa strains from West Africa form the second group. (bl.uk)
Lassa virus (LASV), the cause of the acute viral hemorrhagic illness Lassa fever (LF), is endemic in West Africa . (bvsalud.org)
For example, Lassa fever is limited to rural areas of West Africa where rats and mice carry the virus. (medlineplus.gov)
Lassa fever is spread by rodents and is common in West Africa, where it kills an estimated 30,000 to 40,000 people every year-approximately 10 to 15 percent of those infected. (globalbiodefense.com)
As of 2012 discoveries within the Mano River region of west Africa have expanded the endemic zone between the two known Lassa endemic regions, indicating that LASV is more widely distributed throughout the tropical wooded savannah ecozone in west Africa. (wikipedia.org)
By 1972, the multimammate rat, Mastomys natalensis, was found to be the main reservoir of the virus in West Africa, able to shed virus in its urine and feces without exhibiting visible symptoms. (wikipedia.org)
Specific variants of the genes encoding these proteins appear to be under positive selection in West Africa where Lassa is endemic. (wikipedia.org)
The researchers projected that areas hospitable to Lassa virus spread may extend from West Africa into Central and East Africa in the next several decades. (andersen-lab.com)
More hopefully, the researchers examined the dynamics of the spread of Lassa virus using data on sequenced viral genomes sampled at various locations in West Africa and found that virus dispersal appeared to be slow. (andersen-lab.com)
The Lassa virus is transmitted by rats and causes large seasonal outbreaks in West Africa, according to the CDC. (ajc.com)
There are Lassa fever outbreaks every year in Nigeria, typically between the months of December and May, and the disease is endemic to West Africa, according to Dr. Pierre Rollin, an expert in hemorrhagic diseases at the US Centers for Disease Control and Prevention (CDC). (buzzfeednews.com)
The reservoir for the virus is a rodent that exists all over West Africa [multimammate rat], and it's chronically infected with Lassa all year," Rollin says. (buzzfeednews.com)
Among the family, Lassa virus and Junin virus generate periodic annual outbreaks of severe human hemorrhagic fever (HF) in endemic regions of West Africa and Argentina, respectively. (cancerdir.com)
Background: Lassa fever is a viral haemorrhagic disease endemic to west Africa. (harvard.edu)
Lassa fever is endemic in West Africa and has been reported from Sierra Leone, Guinea, Liberia, and Nigeria. (folkhalsomyndigheten.se)
Studies reported in English, that investigated Lassa fever with reference to West Africa were identified using the Medline Entrez-PubMed search and were used for this review. (folkhalsomyndigheten.se)
Lassa fe- Lassa virus in many more districts and states in en- ver is endemic in West Africa and has been reported demic countries of the West African sub-region and from Sierra Leone, Guinea, Liberia, and Nigeria4-7. (folkhalsomyndigheten.se)
Lassa reported in English, that investigated Lassa fever with virus is spherical in shape and measures between 70 reference to West Africa were identified using the and 150 nm in diameter (Fig. 1). (folkhalsomyndigheten.se)
Combinations of face envelope with T-shaped spikes measuring 7-10 key words such as Lassa fever and West Africa were nm and built with glycoprotein. (folkhalsomyndigheten.se)
Довідковий матеріал Lassa fever is an often fatal arenavirus infection that occurs mostly in West Africa. (msdmanuals.com)

2014, two persons died of confirmed Lassa virus (LASV) transcription PCRs: 1 specific for LASV and 1 for panare- infection at Saint Jean de Dieu Hospital, in Tanguieta, naviruses ( 6 , 7 ). (cdc.gov)
During the same period, 2 cases quences of 1,654 nt were aligned with 31 LASV sequences from neighboring Togo were also confirmed as Lassa belonging to all lineages. (cdc.gov)
Old world viruses include the Lassa virus (LASV) and Lujo fever in Africa, while New World viruses include several viral hemorrhagic fevers (Junin, Machupo, Guanarito, Sabia, Chapare) found in South America. (medscape.com)
Lassa mammarenavirus (LASV) is an arenavirus that causes Lassa hemorrhagic fever, a type of viral hemorrhagic fever (VHF), in humans and other primates. (wikipedia.org)
family members, Lassa disease (LASV) and Junin disease (JUNV) generate regular annual outbreaks of serious human being hemorrhagic fever (HF) in endemic regions of Western world Africa and Argentina, respectively. (cancerdir.com)
LASV may be the many prevalent and harmful arenavirus, leading to over 300,000 situations of Lassa fever each year and between 5,000 and 10,000 fatalities [1]. (cancerdir.com)
With rejuvenated interest in LF and a call for accelerated research on the Lassa virus (LASV) vaccine, there is a need to define the correlates of natural protective immune responses to LF. (kent.ac.uk)
No large-scale studies exist from Nigeria, where the Lassa virus (LASV) is most diverse. (harvard.edu)

Lujo hemorrhagic fever (LUHF) is caused by Lujo virus, a single-stranded virus of the Arenaviridae family. (cdc.gov)
The Whitewater Arroyo virus: natural evidence for genetic recombination among Tacaribe serocomplex viruses (family Arenaviridae). (wikigenes.org)
The following are the major viruses and the other recognized Arenaviridae listed in relationship to their rodent reservoirs. (medscape.com)
West African sub-region with consideration of the mented RNA virus belonging to the Arenaviridae origin of the virus, its properties/strains, epidemiol- family. (folkhalsomyndigheten.se)
Lassa virus is a single-stranded RNA virus in the Arenaviridae family. (msdmanuals.com)

To deter- outbreak with 11 confirmed cases of Lassa fever occurred mine phylogeny more reliably than we could by using short in the communes of Tchaourou and Parakou, department fragments issued from the diagnostic tests, we performed of Borgou, central Benin. (cdc.gov)
There have been more confirmed cases of Lassa fever in the first two months of 2018 than there have been in the last two years combined. (buzzfeednews.com)
Since January 1, there have been 353 laboratory confirmed cases of Lassa fever and 78 deaths, according to the Nigeria Centre for Disease Control , compared with 143 confirmed cases in all of 2017 and 109 in 2016. (buzzfeednews.com)

Alpha-dystroglycan is also used as a receptor by viruses of the New World clade C arenaviruses (Oliveros and Latino viruses). (wikipedia.org)
In contrast, the New World arenaviruses of clades A and B, which include the important viruses Machupo, Guanarito, Junin, and Sabia in addition to the non pathogenic Amapari virus, use the transferrin receptor 1. (wikipedia.org)
Arenaviruses are single-stranded ribonucleic acid (RNA) viruses that cause chronic infections in rodents and zoonotically acquired disease in humans through rodent excreta, especially urine. (medscape.com)
Arenaviruses have been divided into 2 groups based on whether the virus is found to infect Old World (ie, Eastern Hemisphere) rodents (family Muridae, subfamily Murinae) or New World (ie, Western Hemisphere) rodents (family Muridae, subfamily Sigmodontinae). (medscape.com)
The New World arenaviruses are further divided into 3 lineages designated clades: A, B, C. LCM virus is the only arenavirus to exist in both areas but is classified as an Old World virus. (medscape.com)
Like other arenaviruses, Lassa virus lacks a ogy and clinical presentation, treatment, prevention conventional negative-strand coding arrangement and control as well as the current theories of its patho- and the isolates of the virus differ in their genetic, genesis and efforts in vaccine development. (folkhalsomyndigheten.se)

The disease in man and monkeys following infection with Lassa virus was similar. (bl.uk)
Lassa virus produces a fatal haemorrhagic disease while Mopeia isolates produce only an asymptomatic infection. (bl.uk)
[ 3 ] There are 3 possible outcomes for an infected rodent: rapid clearance of virus, development of an acute lethal disease, and persistent chronic infection which is clinically benign but results in the release of virus into excreta, specifically urine. (medscape.com)
We confirmed monkeypox virus infection in the mother, fetus, and placenta by using a monkeypox virus-specific quantitative PCR. (cdc.gov)
Risk for intrauterine infection appears to differ between virus clades, but clinicians should be aware of potential for intrauterine monkeypox virus transmission among pregnant persons during ongoing and future mpox outbreaks. (cdc.gov)
To determine whether Lassa virus was circulating in southern Mali, we tested samples from small mammals from 3 villages, including Soromba, where in 2009 a British citizen probably contracted a lethal Lassa virus infection. (elsevierpure.com)
Statistically, medical personnel exposed to Lassa fever patients are not at a higher risk for Lassa virus infection than the general population. (who.int)
The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Δ32) allele confers strong resistance to infection by the AIDS virus HIV. (harvard.edu)
While several lines of evidence suggest a protective role of T cells against disease associated with Dengue virus (DENV) infection, their potential contribution to immunopathology in the acute phase of DENV infection remains controversial, and it has been hypothesized that the more severe form of the disease (dengue hemorrhagic fever, DHF) is associated with altered T cell responses. (mdpi.com)
3. The interplay between the host innate immune response and RNA virus infection. (upenn.edu)
Hepatitis E virus (HEV), an important agent of viral hepatitis worldwide, can cause severe courses of infection in pregnant women and immunosuppressed patients. (mdpi.com)
And before the outbreak of the virus was over, it had infected a total of 284 persons among whom 150 patients succumbed to the viral infection . (herbs2000.com)
This took the mortality rate owing to the virus infection to a little over 50 per cent! (herbs2000.com)
Like Marburg and Ebola, Lassa fever is also a hemorrhagic fever caused by a deadly viral infection. (herbs2000.com)
In 1934, the prototypic arenavirus, lymphocytic choriomeningitis (LCM) virus, was first isolated during serial monkey passage of human material that was obtained from a fatal infection in the first documented epidemic of St. Louis encephalitis, a totally unrelated virus. (medscape.com)
The virus exhibits persistent, asymptomatic infection with profuse urinary virus excretion in the ubiquitous rodent vector, Mastomys natalensi s. (folkhalsomyndigheten.se)
tent, asymptomatic infection, with profuse urinary virus excretion in Mastomys natalensi s, the ubiqui- The emergence of this highly virulent and contagious tous and highly commensal rodent host2,3. (folkhalsomyndigheten.se)
Based on serologic data, indigenous people in endemic areas have a very high rate of infection-much higher than their rate of hospitalization for Lassa fever-suggesting that many infections are mild and self-limited. (msdmanuals.com)
Ebola virus haemorrhagic fever : proceedings of an International Colloquium on Ebola Virus Infection and Other Haemorrhagic Fevers held in Antwerp, Belgium, 6-8 December 1977 / editor, S. R. Pattyn. (who.int)

These include the Ebola and Marburg, Lassa fever, and yellow fever viruses. (medlineplus.gov)
However, the fact that Lassa, Ebola and Marburg virus antibodies never appeared in the same serum sample leads one to theorize that the endemic regions of the three viruses are well-separated from each other. (who.int)
Considering that active cases of Ebola or Marburg virus disease have never been reported from Liberia, the occurrence of these specific antibodies was surprising. (who.int)
The results seem to indicate that Liberia has to be included in the Ebola and Marburg virus endemic zone. (who.int)
Recent investigations doubt the specificity of the indirect immunofluorescence antibody test concerning Ebola and Marburg viruses (K.M. Johnson, personal communication). (who.int)
Thus the significance of the antibodies to Ebola and Marburg viruses identified in Liberia requires further evaluation. (who.int)
The floviruses, Ebola and Marburg, may cause epidemics, with a high case fatality rate, while Lassa has a lower case fatality rate [ 4 , 5 ]. (omicsonline.org)
Researches have shown that the Ebola viruses are closely related to Marburg. (herbs2000.com)
Both Marburg and the Ebola viruses possessed analogous genetic substances - a solitary filament of RNA (ribonucleic acid). (herbs2000.com)
While both viruses - Ebola and Marburg, have the aptitude to communicate a disease as well as kill monkeys that breathe in the virus, they cannot be easily transmitted taking help of the air or atmosphere. (herbs2000.com)

The Mozambique and Zimbabwe isolates proved to have morphological and physicochemical characteristics not dissimilar from West African Lassa viruses and those members of the arenavirus family from South America. (bl.uk)
The combined data suggests the possibility of two virus groups within the 'Old World' arenavirus classification. (bl.uk)
It is suggested that the Mopeia viruses are minor antigenic variants of Lassa and should be included within the arenavirus family. (bl.uk)
It shares this receptor with the prototypic Old World arenavirus lymphocytic choriomeningitis virus. (wikipedia.org)
The usage of these different remedies is normally a direct effect of the various mechanism of security linked to both arenavirus HF: security in Argentine HF is dependant on induction of a solid humoral immune system response [8] whereas in Lassa fever affected individual recovery is principally linked to cell-mediated immune system response with low antibody creation [1]. (cancerdir.com)
Lassa fever, which is caused by an arenavirus, can affect multiple organs and cause bleeding in late stages. (upr.org)
Sequence of the nucleocapsid protein gene of Machupo virus: close relationship with another South American pathogenic arenavirus, Junín. (wikigenes.org)
Lassa fever is an acute viral zoonotic illness caused by Lassa virus, an arenavirus known to be responsible for a severe haemorrhagic fever characterised by fever, muscle aches, sore throat, nausea, vomiting and, chest and abdominal pain. (folkhalsomyndigheten.se)

Viral hemorrhagic fevers (VHFs) are a group of illnesses caused by four families of viruses. (medlineplus.gov)
Not a lot of research has been done on neglected tropical fevers like Lassa, which cause profound public health and economic problems," said Sullivan. (globalbiodefense.com)
Nowadays, in Africa many viruses are known to cause haemorrhagic fevers including Ebola, Magdeburg and yellow fever . (omicsonline.org)

Lu Jianhong, Han Ziying, Liu Yuliang, Liu Wenbo, Lee Michael S, Olson Mark A, Ruthel Gordon, Freedman Bruce D, Harty Ronald N A host-oriented inhibitor of Junin Argentine hemorrhagic fever virus egress. (upenn.edu)

A direct comparison was made with a patient diagnosed as having Lassa fever. (bl.uk)

Ebola virus disease outbreak occurred in 2014 in Liberia, Guinea and Sierra Leone, Monkeypox virus in Nigeria in 2017 and most recently Lassa virus in Nigeria, Togo and Benin in 2018. (who.int)
Argonne's own team of structural biologists has also been working around the clock since the COVID-19 outbreak began, using the APS to precisely determine the shape and structure of the proteins that make up the virus and laying the groundwork for drug treatments and vaccines. (anl.gov)
There is a Lassa outbreak in Benin, which is next to Togo. (ajc.com)
An outbreak of Lassa fever in Nigeria has infected more than 350 people since January. (buzzfeednews.com)
Nigeria is experiencing a smoldering Lassa fever outbreak. (upr.org)
The Lassa outbreak reveals a few inherent cracks in Nigeria's system and raises good lessons in determining how a country or region can best respond to emerging infections. (upr.org)
It was piloted using a Lassa fever (LF) outbreak scenario. (biomedcentral.com)

The virus can pass from human to human, causing devastating outbreaks of a hemorrhagic disease similar to Ebola virus. (globalbiodefense.com)
In the study, which appeared on September 27, 2022, in Nature Communications , scientists analyzed decades of environmental data associated with Lassa virus outbreaks, revealing temperature, rainfall and the presence of pastureland areas as key factors contributing to viral transmission. (andersen-lab.com)
Since the Lassa fever outbreaks typically last until April or May, Rollin says, there is still some time to go before the Ministry of Health has final numbers. (buzzfeednews.com)
Scientists analyzed decades of environmental data associated with Lassa virus outbreaks, revealing temperature, rainfall, and the presence of pastureland areas as key factors contributing to viral transmission. (packseguidores.cl)
More recently, it investigated anthrax attacks after the Sept. 11 terrorist attacks, as well as outbreaks of the West Nile and H1N1 viruses. (zdnet.com)
Furthermore, Lassa virus has cluding Liberia, Sierra Leone, Guinea, Mali and been associated with nosocomial outbreaks with high Senegal5-7. (folkhalsomyndigheten.se)

To date, little is known about how the body's innate immune response (interferons, cytokine proteins, inflammatory cells) and adaptive immune response (T and B cells, antibodies) react to the hemorrhagic virus infections. (globalbiodefense.com)
But like Ebola, it's a so-called hemorrhagic virus because it can cause bleeding in the mouth and gastrointestinal tract in severe cases. (buzzfeednews.com)

An American health care worker with a suspected case of Lassa fever has been transported to metro Atlanta for treatment at Emory University Hospital. (ajc.com)

Lujo virus is the second African hemorrhagic fever virus described. (cdc.gov)

In 1969, missionary nurse Laura Wine fell ill with a mysterious disease she contracted from an obstetrical patient in Lassa, a village in Borno State, Nigeria. (wikipedia.org)
Lassa fever is not new and was first identified in 1969. (buzzfeednews.com)
Lassa virus was identified in 1969. (cdc.gov)

Lassa virus is a "zoonotic" virus that spreads to humans from other animals-in this case, the Natal multimammate rat ( Mastomys natalensis ), most likely via its droppings. (andersen-lab.com)
Lassa fever is an animal-borne, or zoonotic, acute viral illness spread by the common African rat. (cdc.gov)
Lassa virus is a "zoonotic" virus that spreads from other animals to humans. (packseguidores.cl)
DMT's general work philosophy/strategy combines areas such as 'molecular biology', 'tissue culture', 'immunology' and 'animal models' with the goal to develop vaccines and therapeutics for emerging zoonotic viruses, the mission of the Laboratory of Virology, Division of Intramural Research (DIR) and NIAID. (nih.gov)

The worker had cared for or had contact with a Lassa fever patient at a hospital in Togo," according to the Centers for Disease Control and Prevention. (ajc.com)

Scientists from The Scripps Research Institute (TSRI) have been awarded $6.6 million from the National Institutes of Health (NIH) to lead an investigation of Lassa fever virus, the most prevalent virus-induced hemorrhagic fever disease in Africa. (globalbiodefense.com)
New analysis by scientists at Scripps Research and University of Brussels finds that climate change and other factors could soon make deadly Lassa fever a much bigger public health problem in Africa. (andersen-lab.com)
Our analysis shows how climate, land use, and population changes in the next 50 years could dramatically increase the risk of Lassa fever in Africa," says first author Raphaëlle Klitting, PhD, a postdoctoral researcher at Scripps Research during the study. (andersen-lab.com)
Combining the model with projections of climate and land-use changes in Africa in the next several decades, as well as the known range of the Natal multimammate rat, the researchers estimated the areas of Africa that could support Lassa virus transmission currently, and in the years 2030, 2050, and 2070. (andersen-lab.com)
We found that several regions will likely become ecologically suitable for virus spread in Central Africa, including in Cameroon and the Democratic Republic of the Congo, and even in East Africa, in Uganda," Klitting said. (andersen-lab.com)
The authors say that the findings should inform African public health policies, for example, by encouraging officials to add Lassa virus to lists of viruses under epidemiologic surveillance in parts of Central and East Africa. (andersen-lab.com)

Seroprevalence of anti-Lassa Virus IgG antibodies in three districts of Sierra Leone: A cross-sectional, population-based study. (bvsalud.org)
Antiviral therapies are limited by the usage of immune system convalescent plasma with described dosages of JUNV-neutralizing antibodies, suggested for Argentine HF sufferers [2], or the guanosine analog ribavirin (1-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) (RIB), effective against Lassa fever by intravenous administration [7]. (cancerdir.com)
Since VHF share symptoms with many other diseases, positive identification of the disease relies on laboratory evidence of the viruses in the bloodstream, such as detection of antigens and antibodies or isolation of the virus from the body. (who.int)
When the body clears out a virus, a person's blood has immune system proteins called antibodies. (mayoclinic.org)
The plasma has different amounts of antibodies used to block the virus that caused the illness. (mayoclinic.org)
A research team has discovered important details about how therapeutically relevant human monoclonal antibodies can protect against Crimean Congo Hemorrhagic Fever virus. (sciencedaily.com)
The therapeutic role for non-neutralizing antibodies in preventing disease is becoming more evident for high-risk pathogens such as Ebola, Lassa, and Nipah virus. (sciencedaily.com)

citation needed] Nucleotide studies of the genome have shown that Lassa has four lineages: three found in Nigeria and the fourth in Guinea, Liberia, and Sierra Leone. (wikipedia.org)
Crimean-Congo hemorrhagic fever virus) 5 to capture the majority of phylogenetic lineages and mitigate diagnostic errors on clinical interpretation. (nature.com)

2. Focusing on Host Cell Elements: Benefits and drawbacks Since certified antiviral medicines in current make use of against other infections focus on viral proteins, they're usually virus-specific and so are susceptible to induce the fast appearance of viral resistant mutants. (cancerdir.com)
Richard Lucey, an infectious diseases expert at Georgetown University who had studied the early data, told Science magazine that the virus must have been circulating silently in Wuhan well before the cluster of infections broke out at the markets. (smh.com.au)

Lassa fever is named after the town in Nigeria where the first cases occurred. (cdc.gov)
The Ministry of Health in Nigeria has improved survey techniques, Rollin says, and there are now three laboratories in the country that can confirm the Lassa fever diagnosis, so this could also contribute to the increase in confirmed cases. (buzzfeednews.com)

Lymphocytic choriomeningitis virus (LCMV) is an enveloped single-stranded RNA virus first isolated in the cerebrospinal fluid of a woman during the 1933 Saint Louis encephalitis epidemic. (medscape.com)
citation needed] Unlike most enveloped viruses which use clathrin coated pits for cellular entry and bind to their receptors in a pH dependent fashion, Lassa and lymphocytic choriomeningitis virus instead use an endocytotic pathway independent of clathrin, caveolin, dynamin and actin. (wikipedia.org)

The surprising finding new reservoir for Lassa virus in Ghana, Togo, and Benin. (cdc.gov)
Often 1 or a few rodent species serves as the natural reservoir for a given virus. (medscape.com)
Although the primary animal reservoir for Lassa virus is known, the virus spreads in only some-not all-areas where these animals are present. (andersen-lab.com)

When it comes to the structure of the SARS-CoV-2 virus, which causes COVID-19 , much of the world's collected data comes from work performed at the Advanced Photon Source ( APS ), a U.S. Department of Energy ( DOE ) User Facility located at DOE 's Argonne National Laboratory. (anl.gov)
However, these symptoms are typically mild, so a person may recover and never know that they had Lassa fever, which has to be confirmed with laboratory testing. (buzzfeednews.com)
Once a laboratory test confirms someone has Lassa fever, there are typically two types of treatment. (buzzfeednews.com)
And we should not mix up the claim of an accidental leak of a naturally occurring virus with the claim that the virus was constructed or manipulated in a laboratory to become more potent. (smh.com.au)

There are no approved vaccines against Lassa fever for use in humans. (wikipedia.org)
Overall, our research activities are targeted towards a better understanding of virus biology and virus-induced host responses to foster the development of vaccines and therapeutics. (nih.gov)

2.2 Transmission of haemorrhagic fever viruses. (who.int)
There are 14 distinct viruses associated with haemorrhagic fever in humans. (who.int)

We are delighted to continue our long-lasting collaboration with Themis and CEPI that has already delivered high potential vaccine candidates for Chikungunya, nearing phase 3, and Lassa fever in phase 1, both emerging infectious diseases representing a threat to global health. (pasteur.fr)

The virus is a complex system made up of at least 29 different proteins, and structural genomics will be the key to finding a treatment or a vaccine to curb this pandemic. (anl.gov)
There is no vaccine for Lassa fever, and early treatment is critical. (buzzfeednews.com)
Elucidating the adaptive immune characteristics of natural protection to Lassa fever (LF) is vital in designing and selecting optimal vaccine candidates. (kent.ac.uk)
DMT's main vaccine platform is the recombinant vesicular stomatitis virus (VSV) system. (nih.gov)
It is clear that an effective vaccine against Covid-19 is crucial if we are to beat this virus. (pasteur.fr)

Lassa fever is spread to humans from infected rodents. (buzzfeednews.com)
Lassa fever is normally spread to humans from rodents carrying the Lassa virus. (buzzfeednews.com)
Lassa fever is caused by a virus that normally infects rodents. (buzzfeednews.com)
The Lassa virus, which is carried and transmitted by rodents for the most part, poses different challenges. (upr.org)

Humans usually get the virus from contact with infected rats or their urine and feces, says Rollin, which happens when people try to trap the rats or if they ingest contaminated food. (buzzfeednews.com)

[ 5 , 6 ] Both vertical transmission to rodent offspring and horizontal spread contribute to the maintenance of virus in the rodent population. (medscape.com)
The rats carry the virus without any symptoms, so there's no way to tell whether a rodent is sick with it or not. (buzzfeednews.com)

Lassa virus has been identified in 3 pygmy mice, Mus baou- mice, 6 Mastomys natalensis mice, and 26 Crocidura spp. (cdc.gov)
In this case, the virus spreads from the Natal multimammate rat ( Mastomys natalensis ), most likely via its droppings. (packseguidores.cl)
The Natal multimammate mouse (Mastomys natalensis), also known as the Natal multimammate rat, spreads the Lassa virus. (packseguidores.cl)

In fact, the strains of Ebola that struck people in Zaire appeared to be somewhat different from the strains of the virus that attacked people in Sudan earlier. (herbs2000.com)
What is more remarkable regarding the strains of Ebola virus is that these filoviruses are actually not as infective as they were initially seemed to be. (herbs2000.com)

By 2022 the virus that causes COVID-19 had mutated. (mayoclinic.org)

Viruses 15(1):146, 2023. (msdmanuals.com)

the only exception is the four dengue viruses, which may circulate continually among humans. (who.int)
The Australian government says it's most likely that the virus was transferred from an animal to humans at Wuhan's wet market. (smh.com.au)
LCM virus was the first recognized cause of aseptic meningitis in humans. (medscape.com)
Загальні відомості про арбовірусні, аренавірусні та філовірусні інфекції Arbovirus (arthropod-borne virus) applies to any virus that is transmitted to humans and/or other vertebrates by certain species of blood-feeding arthropods, chiefly insects (flies and mosquitoes). (msdmanuals.com)

Consistent with the occurrence of active Lassa fever cases, the prevalent Lassa virus activity seems to be in Lofa County and neighbouring Guinea. (who.int)
Convincing conclusions concerning the endemic areas of the three viruses studied were complicated by the movements of the tested persons within Liberia and neighbouring Guinea. (who.int)

Lassa mammarenavirus is an emerging virus and a select agent, requiring Biosafety Level 4-equivalent containment. (wikipedia.org)
Samples from Pinneo were sent to Yale University in New Haven where a new virus, that would later be known as Lassa mammarenavirus, was isolated for the first time by Jordi Casals-Ariet, Sonja Buckley, and others. (wikipedia.org)
Lassa mammarenavirus replicates very rapidly, and demonstrates temporal control in replication. (wikipedia.org)
Lassa mammarenavirus gains entry into the host cell by means of the cell-surface receptor the alpha-dystroglycan (alpha-DG), a versatile receptor for proteins of the extracellular matrix. (wikipedia.org)

There are treatments for Lassa, and most have a mild illness, the CDC said. (ajc.com)

In some areas of Sierra Leone and Liberia, about 10-16% of people admitted to hospitals annually have Lassa fever. (cdc.gov)
The results demonstrate that Lassa fever is endemic in Liberia. (who.int)

Those contributions began in January, when the genome of the virus became available. (anl.gov)

The CDC said it is sending a team to Benin and a staff member to Togo to help respond to Lassa fever. (ajc.com)

Anatomy1

Organisms12

Diseases4

Chemicals and Drugs6

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes2

Geographicals4

West Africa22

LASV8

Arenaviridae5

Cases of Lassa fever3

Arenaviruses6

Infection19

Marburg10

Arenavirus8

Fevers3

Junin1

Having Lassa fever1

Outbreak7

Outbreaks6

Hemorrhagic virus2

Case of Lassa fever1

Lujo1

19693

Zoonotic4

Centers for Diseas1

Africa6

Antibodies7

Lineages2

Infections2

Nigeria2

Lymphocytic2

Reservoir3

Laboratory4

Vaccines2

Haemorrhagic2

Chikungunya1

Vaccine5

Rodents4

Urine and feces1

Rodent2

Mastomys3

Strains2

20221

20231

Humans4

Guinea2

Mammarenavirus4

Illness1

Liberia2

Genome1

Togo1