• receptor
  • Interestingly, the hydrazide method isolated a number of other N-linked glycoproteins also known to be involved in breast cancer including, epidermal growth factor receptor (EGFR), CD44, and the breast cancer 1, and early onset isoform 1 (BRCA1) biomarker. (pubmedcentralcanada.ca)
  • The data support a viral entry mechanism dependent on binding to the lysosome-resident receptor LAMP1 and further dissociation of the membrane-distal GP1 subunits. (nih.gov)
  • degradation
  • Although indicating the potential importance of this part in amyloidogenic processing, these fragments also have been proposed to be intermediates of the final degradation of APP in lysosomes ( Haass and Selkoe, 1993 ). (jneurosci.org)
  • cells
  • Accordingly, cell surface expression of LAMP1 is seen in cells with migratory or invasive functions, such as cytotoxic T cells, platelets and macrophages. (wikipedia.org)
  • Lysosomes are cell organelles found in most animal cells. (wikipedia.org)
  • Lysosomes of mammalian cells typically appear as small, spherical bodies with amorphous, electron-dense cores and a single limiting membrane. (beds.ac.uk)
  • density
  • Lysosomes appear electron dense by comparison with endosomes and can be separated by density gradient centrifugation. (beds.ac.uk)
  • cancer
  • Analyzing the N-glycoproteins from membranes of breast cancer cell lines highlights the usefulness of the procedure for generating a practical set of potential biomarkers. (pubmedcentralcanada.ca)
  • Epigenetic silencing of microRNA-373 to epithelial-mesenchymal transition in non-small cell lung cancer through IRAK2 and LAMP1 axes. (nih.gov)
  • surface
  • however, due to the phenomenon of antigenic variation, intrinsic to the parasite's outer coat of variable surface glycoprotein, this has not yet been achieved. (oatd.org)
  • host
  • A unique triad of histidines of Lassa Virus GP1 forms a binding site for host LAMP1. (nih.gov)