• Sitagliptin and simvastatin combination is used together with a proper diet and exercise to treat type 2 diabetes. (mayoclinic.org)
  • Appropriate studies have not been performed on the relationship of age to the effects of sitagliptin and simvastatin combination in the pediatric population. (mayoclinic.org)
  • Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sitagliptin and simvastatin combination in the elderly. (mayoclinic.org)
  • However, elderly patients are more likely to have age-related kidney or muscle problems, which may require caution and an adjustment in the dose for patients receiving sitagliptin and simvastatin combination. (mayoclinic.org)
  • It is also available as the fixed-dose combinations of sitagliptin/metformin (Janumet, Janumet XR) and sitagliptin/simvastatin (Juvisync). (wikipedia.org)
  • On October 7, 2011, the FDA approved an oral combination of sitagliptin/simvastatin marketed in the US as Juvisync. (wikipedia.org)
  • Simvastatin belongs to the group of medicines called statins. (mayoclinic.org)
  • Simvastatin belongs to a group of drugs called HMG-CoA reductase inhibitors, also known as statins. (rxwiki.com)
  • Simvastatin is a prescription medication used to treat high cholesterol , high triglycerides, and disease of the heart and blood vessels. (rxwiki.com)
  • Your doctor will probably order a blood test to measure liver function before you start taking simvastatin. (rxwiki.com)
  • Juvisync is a convenience combination and should only be prescribed when it is appropriate for a patient to be placed on both of these drugs," states the agency. (medscape.com)
  • Due to restrictions on using simvastatin 80 mg in patients because of concerns about muscle toxicity, the combination will not be available with high-dose simvastatin. (medscape.com)