Binding proteinReduces lipopolysaccharide-inducedMacrophagesInflammationExposureOxidative stressMiceEndotoxinMembraneLPSsAcute lung i10.1371MitochondrialEndotoxinsPeriodontalGenePathophysiologyImmuneBacterial infectionsGram-negativeVitroMicrobiologyARDSLiverExperimentalModelRigorous peer reviewResponseTissueStrainStudyInjury2020Peer review
Binding protein3
- Lipopolysaccharide binding protein (LBP) is a protein that in humans is encoded by the LBP gene. (wikipedia.org)
- Lipopolysaccharide-binding protein has been shown to interact with CD14, TLR2, TLR4 and the co-receptor MD-2. (wikipedia.org)
- 1994). "Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. (wikipedia.org)
Reduces lipopolysaccharide-induced1
- N-acetylserotonin reduces lipopolysaccharide-induced lipid peroxidation in vitro more effectively than melatonin. (nel.edu)
Macrophages1
- Down-regulation of mannose receptor activity in macrophages after treatment with lipopolysaccharide and phorbol esters. (aai.org)
Inflammation3
- Furthermore, long-term lipopolysaccharide (LPS) exposure mimicking immunosuppression in the resolution phase of inflammation synergistically increased Dex-mediated TLR2 upregulation. (frontiersin.org)
- Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids. (northumbria.ac.uk)
- Dive into the research topics of 'Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids. (northumbria.ac.uk)
Exposure3
- This study examined the role of cytosolic and mitochondrial glutathione in protecting hepatocytes from oxidative stress during exposure to lipopolysaccharide. (eurekamag.com)
- RESULTS To address this question, we have examined the differential expression of 104 miRNAs using real-time PCR during the innate immune response in mouse lung following exposure to aerosilised lipopolysaccharide (LPS). (northumbria.ac.uk)
- The aim of this study is to measure the level of IgE, IgG 4 , and IgG 4 /IgE ratio periodically after exposure of periodontal pathogen Pg lipopolysaccharide (LPS). (unair.ac.id)
Oxidative stress3
- Glutathione may have an important role in cellular defenses against lipopolysaccharide-induced liver damage in mice, and excessive oxidative stress may precipitate the mitochondrial membrane permeability transition in hepatocytes and lead to cell death. (eurekamag.com)
- Oxidative stress caused by mitochondrial abnormalities play an important role in the pathophysiology of lipopolysaccharide (LPS)-induced memory impairment. (biomedcentral.com)
- Our previous studies have shown that oxidative stress and inflammatory responses play an important role in the mouse memory impairment model caused by lipopolysaccharide (LPS). (biomedcentral.com)
Mice2
- The changes of hepatic glutathione content following lipopolysaccharide challenge (2 mg/kg) were measured in mice by reverse-phase high-performance liquid chromatography. (eurekamag.com)
- Lipopolysaccharide (LPS) derived from the outer membrane of gram-negative bacteria induces acute lung injury (ALI) in mice. (nih.gov)
Endotoxin3
- Lipopolysaccharide (LPS) is an endotoxin derived from the cell walls of these bacteria. (jneurosci.org)
- Lipopolysaccharide (LPS), a bacterial endotoxin located in the outer membrane of the cell wall of the Gram-negative bacteria, is considered as the principal factor responsible for multiple organs damage including myocardial injury in patients with sepsis [ 2 , 3 ]. (biomedcentral.com)
- Quantitative studies have demonstrated that a purified lipopolysaccharide (endotoxin) derived from the O-901 strain of Salmonella typhosa markedly enhanced the antibody response of rabbits when given separately or in conjunction with protein antigens. (umn.edu)
Membrane3
- In addition, the possible participation of changes of inner mitochondrial membrane permeability in lipopolysaccharide-induced hepatotoxicity was investigated. (eurekamag.com)
- NMR studies in the presence of lipopolysaccharide provided structural insights into the mechanisms underlying this, notably in relationship to outer membrane permeabilization. (lu.se)
- Similarly to Gram-negative bacteria, cyanobacterial cell wall contains Lipopolysaccharides (LPSs) in the outer membrane layer. (scirp.org)
LPSs2
- Different kinds of microorganisms express different PAMPs, including mainly lipopolysaccharides (LPSs), phosphoteichoic acid, peptidoglycan, and other structures that usually do not exist in the host. (frontiersin.org)
- When Gram-negative bacteria enter the bloodstream, they release lipopolysaccharides, or LPSs, which activate the innate immune system. (asbmb.org)
Acute lung i1
- In our experiment, adult SD rat model of acute lung injury was established by injecting lipopolysaccharide (LPS) into treachea, and life signs and dry-wet ratio of pulmonary tissue were closely observed. (researchsquare.com)
10.13713
Mitochondrial1
- There was increased production of ROI along with depletion of cellular and mitochondrial glutathione in the liver after lipopolysaccharide administration. (eurekamag.com)
Endotoxins1
- This antibody-enhancing property was found to be common to a broad group of endotoxins from Gram-negative bacilli and was not restricted to the lipopolysaccharide derived from S. typhosa. (umn.edu)
Periodontal1
- Using a human monocytic cell line, we demonstrate that Porphyromonas gingivalis lipopolysaccharide (LPS), which is a major etiological factor in periodontal disease, induces only partial immune tolerance, with continued high production of interleukin-8 (IL-8) but diminished secretion of tumor necrosis factor alpha (TNF-a) after repeated challenge. (elsevierpure.com)
Gene4
- Distinct carbohydrate and lipid-based molecular patterns within lipopolysaccharides from Burkholderia cepacia contribute to defense-associated differential gene expression in Arabidopsis thaliana. (uj.ac.za)
- Activation of camalexin biosynthesis in Arabidopsis thaliana in response to perception of bacterial lipopolysaccharides: a gene-to-metabolite study. (uj.ac.za)
- Gene - An International Journal of Functional and Evolutionary Genomics. (uj.ac.za)
- Molecular characterization and regulation of a Nicotiana tabacum S-domain receptor-like kinase gene induced during an early rapid response to lipopolysaccharides. (uj.ac.za)
Pathophysiology1
- Overproduction of reactive oxygen intermediates (ROI) may have an important role in the pathophysiology of lipopolysaccharide-mediated liver-injury. (eurekamag.com)
Immune1
- LBP is a soluble acute-phase protein that binds to bacterial lipopolysaccharide (or LPS) to elicit immune responses by presenting the LPS to important cell surface pattern recognition receptors called CD14 and TLR4. (wikipedia.org)
Bacterial infections1
- Fish were exposed to lipopolysaccharide (LPS), a mimetic of bacterial infections, and copper sulphate (CuSO4), used in aquaculture to control algae and outbreaks of infectious diseases. (birmingham.ac.uk)
Gram-negative2
- Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. (wikipedia.org)
- The lipopolysaccharide (LPS), a component of the cell wall of gram-negative bacteria, mediates many of the alterations leading to ES. (biomedcentral.com)
Vitro1
- An in vitro pneumonia model was induced using lipopolysaccharide (LPS) in WI‑38 cells. (spandidos-publications.com)
Microbiology1
- Journal of Medical Microbiology. (wikipedia.org)
ARDS3
- We aim to explore whether astragaloside IV is effective for ARDS treatment in a lipopolysaccharides (LPS)-induced cell model and whether autophagy is involved in the therapeutic function of astragaloside IV. (karger.com)
- Gram-negative bacterial infection with lipopolysaccharides (LPS) is the main cause of ARDS [ 1 ]. (karger.com)
- A549 cells were treated by lipopolysaccharide (LPS) to simulate alveolar epithelial cells in ARDS. (bvsalud.org)
Liver1
- [ 10 ] Expression of LRG1 in liver may be upregulated by lipopolysaccharide and by mediators of acute-phase response such as interleukin 6. (medscape.com)
Model1
- The present study was designed to explore its effects in a mouse model of sepsis-related encephalitis by intravenous administration of lipopolysaccharide (LPS). (biomedcentral.com)
Rigorous peer review1
- Fortune Journals follows a rigorous peer-review together with strict ethical policies and standards to ensure high quality scientific works to the field of scholarly publication. (fortunejournals.com)
Response1
- We identify 76 enhancer RNAs (eRNAs), 40 canonical lncRNAs, 65 antisense lncRNAs and 35 regions of bidirectional transcription (RBT) that are differentially expressed in response to bacterial lipopolysaccharide (LPS). (bath.ac.uk)
Tissue1
- Lipopolysaccharide mobility in leaf tissue of Arabidopsis thaliana. (uj.ac.za)
Strain1
- Deciphering the structural and biological properties of the lipid A sub-component of lipopolysaccharides from Burkholderia cepacia strain ASP B 2D, in Arabidopsis thaliana. (uj.ac.za)
Study1
- This study aims to compare the potency of lipopolysaccharide (LPS) and oxidized low-density lipoproteins (oxLDL) to induce plaque formation and increase plaque vulnerability in the carotid artery of hypercholesterolemic Yucatan microswine. (fortunejournals.com)
Injury1
- The aim of this work was to investigate the effect of the extract from Agkistrodon halys venom on lipopolysaccharide (LPS)-induced myocardial injury. (biomedcentral.com)
20201
- Impact Factor - The 2020 Impact Factor as announced by Clarivate Analytics, is 3.89 .The Journal is ranked 36/299 in the category Food Science, 45/516 in the category Public Health, Environmental and Occupational Health and 33/120 in Nutrition & Dietetics. (foodandnutritionresearch.net)
Peer review1
- Fortune Journals follows single blind peer-review process, manuscript submitted by an Author is assigned to a particular Editor. (fortunejournals.com)