Journal keratoconus. Medical search. Frequent questions

You can contact Chinese Journal of Experimental Ophthalmology ( CJEO ) at our Editorial Office in Zhengzhou, China or at our Publishing Offices in Beijing, China. (cjeo-journal.org)
Indian journal of ophthalmology , 63 (9), 722-727. (aston.ac.uk)
British Journal of Ophthalmology , 89 (7), 841-846. (johnshopkins.edu)
Canadian Journal of Ophthalmology , 36 (5), 252-259. (aku.edu)
At an international meeting of contact lens experts, Dr. Carina Koppen, MD, PhD ( left ) of Belgium discussed her research and a recent paper published in the American Journal of Ophthalmology (1). (nkcf.org)
As a keratoconus expert and chief of ophthalmology at Antwerp University, she is trained in both the surgical and medical management of KC. (nkcf.org)

Secondly, it demonstrates one of the limitations of penetrating keratoplasty as a treatment for keratoconus where the entire cornea has a tendency to ectasia. (bmj.com)
Keratoconus and corneal ectasia after LASIK. (ijkecd.com)
Several methods have been described in the literature to both evaluate and document progression in keratoconus, but there is no consistent or clear definition of ectasia progression. (scienceopen.com)
Keratoconus is a bilateral noninflammatory corneal ectasia with an incidence of approximately 1 per 2,000 in the general population. (scienceopen.com)
This article discusses corneal collagen cross-linking with riboflavin, the latest addition to our armamentarium for the treatment of keratoconus and for stabilizing corneal ectasia after keratorefractive surgery. (crstoday.com)
Keratoconus is a common complex corneal ectasia that can lead to severe visual impairment. (edu.au)
Three-Step Treatment of Keratoconus and Post-LASIK Ectasia: Implantation of ICRS, Corneal Cross-linking, and Implantation of Toric Posterior Chamber Phakic IOLs. (freevis.de)
When you do your research, you will learn about the rare possibilities for LASIK complications , including post-LASIK keratoconus and corneal ectasia. (americanrefractivesurgerycouncil.org)
To help make sense of ectasia, we interviewed John Vukich, M.D., chair of the refractive surgery clinical committee for the American Society for Cataract and Refractive Surgery, to answer questions about both keratoconus and post-LASIK ectasia. (americanrefractivesurgerycouncil.org)
Similar to keratoconus, ectasia is a weakening of the cornea following refractive surgery that can lead to corneal bulging and vision loss. (americanrefractivesurgerycouncil.org)
Having an irregular or steep cornea may be a telltale sign of subclinical keratoconus that may place the patient at risk to develop postoperative ectasia. (americanrefractivesurgerycouncil.org)
In addition to age and family history of keratoconus, other risk factors for ectasia include thin corneas and a high degree of myopia (nearsightedness). (americanrefractivesurgerycouncil.org)
How are keratoconus and ectasia treated? (americanrefractivesurgerycouncil.org)
Treatment for keratoconus and ectasia includes multiple options. (americanrefractivesurgerycouncil.org)
Additionally, topographic laser treatments can also help improve the vision of patients with keratoconus or ectasia. (americanrefractivesurgerycouncil.org)
Worsening vision and progressive corneal ectasia in a patient with keratoconus. (eyerounds.org)
A 22-year-old male with keratoconus was referred for progressive corneal ectasia and worsening visual acuity. (eyerounds.org)

the continued progression of the pathological process of keratoconus in the host cornea leading to peripheral corneal thinning. (bmj.com)
Recurrence of keratoconus in donor cornea 22 years after successful keratoplasty. (bmj.com)
Keratoconus derived from the Greek words "keras" (cornea) and "konos" (cone) is a corneal condition characterized by paraxial corneal stromal thinning and steeping which causes the cornea to bulge out in a cone-shape. (medscape.com)
All layers of the cornea are believed to be affected by keratoconus. (medscape.com)
Some Keratoconus experts have opined that even hard contact lens can have detrimental side effects from constant rubbing against the bulging cornea. (khannainstitute.com)
Keratoconus is a progressive, bilateral and often asymmetric corneal disorder characterized by thinning and steepening of the central and paracentral cornea that causes high myopia and irregular astigmatism [1-3] . (lww.com)
Keratoconus is an ectatic corneal disorder characterized by a change in the organization and structure of the cornea. (touchophthalmology.com)
Three affected members had definite keratoconus, and two were suspects based on mild cone formation in the cornea of at least one eye. (aku.edu)
Keratoconus is a naturally occurring condition that over time weakens the structural integrity of the cornea, which is the front surface of the eye. (americanrefractivesurgerycouncil.org)
Keratoconus is a progressive disease that affects the topography of the cornea, resulting in impaired visual acuity and refractive errors. (ijkecd.com)

Clinical guidelines for the management of keratoconus patien. (lww.com)
ICRS have been used for the management of keratoconus in order to prevent further keratoconus progression and improve visual performance. (ijkecd.com)
1 , 2 Procedures such as the implantation of intrastromal corneal ring segments (ICRS), 3 , 4 and corneal collagen crosslinking 5 - 7 have been recently introduced for the management of keratoconus. (ijkecd.com)

her father, uncle and grandfather were all known cases of keratoconus who were diagnosed in their third decade of life and needed multiple penetrating keratoplasty procedures. (touchophthalmology.com)
By all accounts, these eyes would be defined as advanced or extreme cases of keratoconus. (nkcf.org)
This is a very rare side effect that clinical research is showing to be related to mild, or subclinical (no signs or symptoms), cases of keratoconus. (americanrefractivesurgerycouncil.org)

Slit lamp examination was normal without visible signs of keratoconus or other signs related to connective tissue diseases such as blue sclera. (touchophthalmology.com)
Keratoconus is usually easy enough to determine when patients have obvious signs of keratoconus and avoid LASIK, but the subtler, initial findings are the ones still in discussion and the ones that make screening challenging. (ophthalmologytimes.com)

Early postoperative astigmatism following penetrating keratoplasty (PK) may occur more frequently in keratoconus than other conditions, although all corneal grafts are beset by this problem. (bmj.com)
The work presented in this month's issue of the BJO (p 371 ) by Lim et al on late onset post-keratoplasty astigmatism in patients with keratoconus identifies a subgroup of patients who developed excessive astigmatism years after successful surgery. (bmj.com)
Recently, with the development of a novel dissection technique, interest in deep anterior lamellar keratoplasty (DALK) as a treatment for keratoconus has been renewed. (bmj.com)
Up to now, penetrating keratoplasty (PK) remains the most common surgical procedure to treat severe keratoconus. (oamjms.eu)
In 2003, Wollensak et al introduced corneal collagen cross-linking as an alternative to penetrating keratoplasty for treating progressive keratoconus. (crstoday.com)
Methods: 12 penetrating keratoplasty specimens from patients with keratoconus who had previously undergone epikeratoplasty, eight keratoconus, and seven normal corneas were examined, Immunostaining for Sp1, α1-proteinase inhibitor (α1-PI), and α2-macroglobulin (α2M) were performed. (johnshopkins.edu)
Femtosecond laser-assisted small incision sutureless intrastromal lamellar keratoplasty (SILK) for corneal transplantation in keratoconus Journal of Refractive Surgery. (londonvisionclinic.com)
Penetrating keratoplasty is a well-studied and long established surgery for the treatment of corneal disease such as keratoconus. (eyerounds.org)

Interpretation: We have identified four Pakistani families with a severe form of LCA that is associated with severe keratoconus in some affected members. (aku.edu)
1. Koppen C, et al, Scleral Lenses Reduce the Need for Corneal Transplants in Severe Keratoconus. (nkcf.org)

Sensitivity and specificity of posterior corneal elevation measured by Pentacam in discriminating keratoconus/ subclinical keratoconus. (ijkecd.com)
Evaluation of Scheimpflug imaging parameters in subclinical keratoconus, keratoconus, and normal eyes. (ijkecd.com)
2015;34(4):359-369) reported that tomography was the best way to screen for early or subclinical keratoconus and that posterior corneal elevation abnormalities must be present. (ophthalmologytimes.com)

Keratoconus (KC) is a progressive, assymetrically bilateral etatic corneal disease, characterized by paraxial corneal stromal thinning and steepening. (medscape.com)
Keratoconus is a progressive, assymetrically bilateral etatic corneal disease that causes decreased visual acuities, occurs primarily from irregular astigmatism and myopia induced from the corneal distortion, and secondarily from corneal scarring. (medscape.com)
Only two cases with similar ages have been reported: a 4-year-old girl diagnosed with bilateral keratoconus secondary to chronic persistent eye rubbing, 6 and a 4-year-old child with keratoconus and Down syndrome for whom corneal collagen CXL was performed twice. (touchophthalmology.com)
The most common causes of bilateral low vision included refractive errors, keratoconus and retinal disorders. (who.int)

Rigid contact lenses or scleral lenses (mainstay of vision therapy): Patients with early keratoconus may successfully use spectacles or spherical/toric soft contact lenses. (medscape.com)
In Vietnam, most keratoconus patients come to visit doctor at severe stage and were treated by PK, so we conduct this study. (oamjms.eu)
To evaluate the results of PK for keratoconus in Vietnamese patients. (oamjms.eu)
PK is an effective procedure with high rate of graft survival for keratoconus patients. (oamjms.eu)
The latest treatment techniques for Keratoconus have helped so many Keratoconus patients lead fruitful lives. (khannainstitute.com)
The purpose of this review is to provide evidence-based clinical practice guidelines (CPG) in the management of patients with keratoconus with RGP CLs. (lww.com)
The developed CPG clearly outlines a strategy for the successful fitting of RGP CLs in patients with keratoconus. (lww.com)
The current evidence and consensus-based CPG helps guide clinicians in a successful strategy for fitting RGP CLs in patients with keratoconus. (lww.com)
The use of this CPG can guide clinicians in the process of fitting RGP CLs in patients with keratoconus. (lww.com)
Visual rehabilitation in keratoconus patients depends on disease stage, for example in the early stages eyeglasses and/or soft contact lens with a toric (astigmatism) design could provide satisfactory visual acuity [5,6] . (lww.com)
Rigid gas permeable contact lenses (RGP CLs) provide a tear layer between the irregular corneal surface and the contact lens and thus provide excellent vision for patients with keratoconus and improve patients' quality of life [1,5-7] . (lww.com)
Conclusion: Keratoconus onset may occur in early childhood, especially in patients with strong family history of the disease even in the absence of systemic or ocular risk factors. (touchophthalmology.com)
Crosslinking may be an effective and safe procedure for very young patients diagnosed with keratoconus. (touchophthalmology.com)
The promise of simple, objective, single instrument-based screening for highly asymmetric keratoconus in patients considering LASIK is still more of an idea than reality. (ophthalmologytimes.com)
A minority of patients with keratoconus present with what is traditionally called unilateral keratoconus, or pronounced disease in one eye only. (ophthalmologytimes.com)
But "unilateral" is misleading, Dr. Randleman explained, as patients rarely have keratoconus in only one eye. (ophthalmologytimes.com)
He presented the results of a study comparing 25 clinically normal eyes of patients with definitive keratoconus in the contralateral eye with 50 eyes from 50 patients that had normal evaluations by multiple imaging devices with uneventful LASIK and at least one year of follow-up. (ophthalmologytimes.com)
Inflammatory cytokines have been shown to be over-expressed in patients with keratoconus. (techscience.com)
Aims: To examine histopathological and immunohistochemical changes in lenticules and host of corneal buttons from patients who previously underwent epikeratoplasty for keratoconus. (johnshopkins.edu)
The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study is an observational study that has enrolled 1,209 keratoconus patients to characterize the progression of keratoconus, to determine factors associated with its progression, and to assess its impact on quality of life, Ten percent of the patients were randomly selected at baseline for a retest examination. (wustl.edu)
To determine factors influencing long-term graft survival and visual acuity in 4834 eyes of 4060 patients receiving their first penetrating corneal graft for keratoconus, a large cohort study was performed from a national register of corneal grafts in which data were recorded prospectively and analyzed retrospectively. (edu.au)
However, the Kaplan-Meier survival rate of first penetrating grafts for keratoconus was 17% at 23 years after graft and had not plateaued at this time, indicating that young patients are likely to need 1 or more repeated grafts during their lifetime. (edu.au)
From a clinic population of close to 850 patients with keratoconus, Dr. Koppen selected patients with extremely severe KC for her study. (nkcf.org)
It is estimated that one out of 2,000 people in the population have naturally occurring keratoconus and these are the patients at greatest risk for worsening their corneal bulging following refractive surgery. (americanrefractivesurgerycouncil.org)
We present a case series involving five eyes in four young patients with advanced keratoconus who were implanted with Ferrara intrastromal corneal ring segments (ICRS) followed by phakic intraocular lens (PIOLs). (ijkecd.com)
11 , 12 Previous studies with keratoconus patients with high myopia have already reported on improved visual acuity after the sequential implantation of Intacs 8 and Keraring 13 ICRS and implantable collamer lenses (ICLs) in the posterior chamber, and Intacs 14 ICRS and Artisan in the anterior chamber. (ijkecd.com)
This case series reports on the findings of a group of patients with advanced keratoconus and high myopia who were implanted with Ferrara ICRS followed by the implantation of ICL, Artisan, and Artiflex phakic intraocular lens (PIOL). (ijkecd.com)
This retrospective case series presents the results of the implantation of Ferrara ICRS followed by the implantation of ICL, Artisan, and Artiflex PIOLs in five eyes of four patients (two female and two male) with keratoconus, high myopia, and contact lens intolerance, conducted at Provisão Hospital de Olhos, Maringá, Brazil. (ijkecd.com)
Exome sequencing identification of susceptibility genes in Chinese patients with keratoconus. (cdc.gov)
Whole mitochondrial genome analysis in Chinese patients with keratoconus. (cdc.gov)
Association with Corneal Remodeling Related Genes, ALDH3A1, LOX, and SPARC Genes Variations in Korean Keratoconus Patients. (cdc.gov)
Absence of significant genetic alterations in the VSX1, SOD1, TIMP3, and LOX genes in Brazilian patients with Keratoconus. (cdc.gov)

Her ocular history was also negative for eye trauma, eye rubbing or other ocular risk factors for keratoconus. (touchophthalmology.com)
Although a genetic component is well recognized, the genetic risk factors for keratoconus are yet to be fully elucidated. (edu.au)

If you have a family history of Keratoconus the top experts say you should have these exams to screen for keratoconus eye disease. (khannainstitute.com)
Purpose: To present the diagnosis and management of the youngest-described keratoconus patient, despite the absence of any systemic or local risk factors except the presence of a strongly positive family history of keratoconus. (touchophthalmology.com)
Results: A 4-year-old female child with free past medical and ocular histories, and a strongly positive family history of keratoconus, presented with deterioration in her vision in the previous 6 months as observed by the family. (touchophthalmology.com)
So, early screening before the age of 4 years should be done for all children of a family history of keratoconus. (touchophthalmology.com)
If you have a family history of keratoconus, ask your doctor specifically about your risk with LASIK. (americanrefractivesurgerycouncil.org)
In addition, it is important to know and share your health history - including any family history of keratoconus - with your ophthalmologist. (americanrefractivesurgerycouncil.org)

Corneal higher order aberrations: a method to grade keratoconus. (ijkecd.com)
Alhaji, H. Evaluation of Anterior and Posterior Corneal Higher Order Aberrations for the Detection of Keratoconus and Suspect Keratoconus. (preprints.org)
Aim: To investigate the application of anterior and posterior corneal higher order aberrations (HOAs) in detecting keratoconus (KC) and suspect keratoconus (SKC). (preprints.org)
Conclusion: Anterior and posterior corneal higher order aberrations can differentiate between keratoconus and normal eyes, with a high level of certainty. (preprints.org)
In suspect keratoconus disease however, only anterior corneal HOAs, and in particular coma-like aberrations, are of value. (preprints.org)
Keratoconus causes a reduction in the optical quality of the eye as a result of corneal distortion, corneal scarring and higher-order aberrations. (college-optometrists.org)

The authors speculate that both keratocytes and the corneal epithelium may participate in the development of keratoconus. (johnshopkins.edu)

Keratoconus is an ectatic corneal disorder that can impair the visual acuity. (oamjms.eu)

To our knowledge, this is the youngest diagnosed patient with keratoconus without any systemic disease or other ocular diseases as risk factors/etiologies for keratoconus. (touchophthalmology.com)

The aim of this study was to determine any differences in the collagen molecular and fibrillar packing, or the arrangement of the proteoglycans along the fibril axis, in the stroma of keratoconus and control corneas. (arvojournals.org)
High and low-angle x-ray diffraction patterns from the fibrillar and molecular packing of collagen in keratoconus and control corneas were obtained using a synchrotron radiation source. (arvojournals.org)
The results indicate no difference in interfibrillar spacing between keratoconus and control corneas at normal physiological hydration, or over a range of hydrations (H = 1-11). (arvojournals.org)
Intermolecular spacings were shown to be significantly (P less than 0.001) lower in keratoconus corneas at normal physiological hydration and over a range of hydrations (H = 1-11). (arvojournals.org)
Meridional patterns from the axial distribution of electron density along the collagen fibrils were obtained from untreated control and keratoconus corneas and from the corneas after their proteoglycans were stained with cupromeronic blue. (arvojournals.org)
Analysis of the integrated intensities of the first nine orders of these reflections show there is a difference in the staining behavior of collagen-associated proteoglycans in control and keratoconus corneas. (arvojournals.org)
Determination of the electron density vectors along the collagen fibrils of cupromeronic blue-stained corneas by the use of Patterson functions indicates that the keratoconus corneal stroma has a specific, ordered proteoglycan that is present in lower numbers along the collagen fibrils, and that it stains less with cupromeronic blue or is in a more disordered arrangement than in the controls. (arvojournals.org)
Influence of the reference surface shape for Discriminating between Normal Corneas, Subdimical Keratoconus and keratoconus. (ijkecd.com)
Sp1 nuclear staining of the basal and wing epithelial cells was more intense in lenticules and keratoconus corneas than in normal corneas. (johnshopkins.edu)
Lenticular, host, and keratoconus keratocytes showed positive Sp1 staining, whereas staining was absent in normal corneas. (johnshopkins.edu)
Compared to normal corneas, α1-PI and α2M immunostaining was lower in the lenticules, host, and keratoconus specimens. (johnshopkins.edu)

Izquierdo L, Henriquez MA, Dañin D. Corneal Elevation Values in Normal Eyes, forme fruste Keratoconus and Keratoconus at Different Stages Measured by Scheimpflug Imaging. (ijkecd.com)
To compare corneal elevation values in normal eyes, forme fruste keratoconus (FFKC) and different stages of keratoconus using Scheimpflug imaging. (ijkecd.com)
Reproducibility and repeatability of central corneal thickness measurement in keratoconus using the rotating Scheimpflug camera and ultrasound pachymetry. (ijkecd.com)
Corneal tomography using the Scheimpflug camera Pentacam® HR confirmed the diagnosis of keratoconus in both eyes. (touchophthalmology.com)
Dr. Randleman, who is also Editor-in-Chief of The Journal of Refractive Surgery , presented an analysis of metrics derived solely from Scheimpflug imaging (Pentacam HR, Oculus) for the detection in highly asymmetric eyes with keratoconus. (ophthalmologytimes.com)
The Pentacam HR has been considered by some to be the most useful instrument to diagnose early keratoconus using Scheimpflug imaging, Dr. Randleman said, but there has been little evidence to support that assumption. (ophthalmologytimes.com)
Decentration measurements using Placido corneal tangential curvature topography and Scheimpflug tomography pachymetry difference maps after small-incision lenticule extraction Journal of Cataract and Refractive Surgery. (londonvisionclinic.com)

Multiple metrics can identify early keratoconus in a minority of affected eyes, but none of the metrics consistently identify early corneal abnormalities and none of the metrics identify the same eyes as being at elevated risk for ectatic disease. (ophthalmologytimes.com)

Keratoconus can dramatically increase the risk of ectatic disease following refractive surgery. (ophthalmologytimes.com)
Receive a complimentary subscription to the Journal of Refractive Surgery , the highest-rated journal in the refractive surgery subspecialty, in print and online. (isrs.org)
Corneal epithelial thickness mapping after photorefractive keratectomy for myopia Journal of Refractive Surgery. (londonvisionclinic.com)
Consultation section - Implantable collamer lens case Journal of Cataract and Refractive Surgery. (londonvisionclinic.com)
Transepithelial topography-guided ablation assisted by epithelial thickness mapping for treatment of regression after myopic refractive surgery Journal of Refractive Surgery. (londonvisionclinic.com)
Small incision lenticule extraction (SMILE) for hyperopia: 12 month refractive and visual outcomes Journal of Refractive Surgery. (londonvisionclinic.com)
Aborted SMILE due to false plane creation and strategy for subsequent removal based on corneal layered pachymetry imaging Journal of Cataract and Refractive Surgery. (londonvisionclinic.com)
Performing SMILE in a patient with high astigmatism and nystagmus - A Case Report Journal of Cataract and Refractive Surgery. (londonvisionclinic.com)
Adjustment of spherical equivalent correction according to cap thickness for myopic small-incision lenticule extraction Journal of Refractive Surgery. (londonvisionclinic.com)

This unambiguously demonstrates that the thinning of the stroma that occurs in keratoconus is not a result of closer packing of the collagen fibrils in the stroma. (arvojournals.org)
A randomized, controlled trial of corneal collagen cross-linking in progressive keratoconus: three-year results. (scienceopen.com)
To report the refractive, topographic, and clinical outcomes 3 years after corneal collagen cross-linking (CXL) in eyes with progressive keratoconus. (scienceopen.com)
Herein we report a case of a 4-year-old female child diagnosed with keratoconus for whom corneal collagen CXL was performed. (touchophthalmology.com)

Posterior elevation values increased according to the severity of keratoconus disease. (ijkecd.com)
Comparison of Pentacam and Orbscan IIz on posterior curvature topography measurements in keratoconus eyes. (ijkecd.com)
Corneal volume, pachymetry and correlation of anterior and posterior corneal shape in subclinical and different stages of clinical keratoconus. (ijkecd.com)
Correlation of Corneal Elevation With Severity of Keratoconus by Means of Anterior and Posterior Topographic Analysis. (ijkecd.com)
Anterior and posterior keratometric values were different in keratoconus eyes (p (longdom.org)
Study shows importance of posterior keratometry and posterior aspherisity beside anterior keratometry in topographic evaluation of keratoconus. (longdom.org)

This was a retrospective study of 31 eyes with keratoconus who underwent PK in VNIO from January 2005 to December 2014. (oamjms.eu)

Color Corneal Topography or "Shape Map" - and Ocular Coherence Tomography Pachymetry or "Thickness Map" help diagnose Keratoconus. (khannainstitute.com)

If you are a keratoconus sufferer, than your immediate family like brother and sister should undergo tests to detect this corneal disease. (khannainstitute.com)

2000. Intrastromal inserts in keratoconus and ectatic corneal conditions 2000;95-163. (ijkecd.com)

Dr Auffarth, Dr Kohnen y Dr Savini comparten el éxito obtenido, con sus primeras experiencias, en aplicaciones clínicas con el Pentacam® AXL Wave. (pentacam.com)

PE had the smallest values in normal eyes and increased in FFKC and each progressive stage of keratoconus. (ijkecd.com)
One hundred eyes with progressive keratoconus were randomized into the CXL treatment or control groups. (scienceopen.com)
Riboflavin-ultraviolet-A (UVA) cross-linking (CXL) is a technique introduced in the past decade for the treatment of progressive keratectasia and keratoconus. (touchophthalmology.com)
Recently, CXL has been recommended as an optimal intervention for progressive keratoconus affecting the pediatric population, bearing in mind that pediatric keratoconus has more debilitating progression compared to adult onset type. (touchophthalmology.com)
This process increases the cornea's biomechanical strength by approximately 300% and halts the progressive thinning that occurs with keratoconus. (crstoday.com)
For instance, miR-26b upregulated in Alzerimer's disease, (6) miR - 96 causes nonsyndromic progressive hearing loss (7) and miR -184 causes Familial Keratoconus with Cataract. (ukessays.com)

This study was conducted to determine the agreement and test- retest repeatability of two methods for measuring corneal curvature in keratoconus: keratometry and the First Definite Apical Clearance Lens (FDACL). (wustl.edu)

Those with moderate-to-advanced keratoconus almost always require rigid contact lenses or scleral contact lenses. (medscape.com)

Conclusions: Penetrating grafts performed for keratoconus exhibited better visual outcome and graft survival than grafts performed for other indications. (edu.au)

Purpose: To compare and determine the repeatability of central corneal thickness (CCT) measurements using four noncontact pachymetry instruments in eyes with keratoconus. (aston.ac.uk)
Kumar M, Shetty R, Jayadev C, Dutta D. Comparability and repeatability of pachymetry in keratoconus using four noncontact techniques. (aston.ac.uk)

Although the mechanism of disease association is yet to be determined, SNP rs4954218 is associated consistently with keratoconus and likely tags a functional variant that contributes to disease susceptibility. (edu.au)
IL1A and IL1B gene polymorphisms and keratoconus susceptibility: evidence from an updated meta-analysis. (cdc.gov)
Rare single nucleotide variants in COL5A1 promoter do not play a major role in keratoconus susceptibility associated with rs1536482. (cdc.gov)

This prospective, comparative study included 267 eyes (107 normal eyes, 21 FFKC and 139 keratoconus). (ijkecd.com)
Mean PE was 9.98 ± 5.33 µm in normal eyes, 18.09 ± 9.23 µm in FFKC and 24.97 µm ± 15.89, 37.82 ± 18.64, 46.82 ± 21.41 and 66.07 ± 39.09, in keratoconus stage I, II, III and IV respectively. (ijkecd.com)
2 Several clinical studies have demonstrated that CXL effectively slows keratoconus progression in adult eyes. (touchophthalmology.com)

Keratoconus Treatment Options Expert, Rajesh Khanna, MD. (khannainstitute.com)
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This treatment plan is based on the recommendations of The roundtable of Global Keratoconus Experts on Treatment of Keratoconus. (khannainstitute.com)
The helpful staff will also work to see if your Medical Insurance will contribute towards treatment of your Keratoconus disease. (khannainstitute.com)
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Call 310-896-4944 to learn more or read on about the latest in Keratoconus treatment and see how people have benefited from services of Keratoconus author and App creator Dr.Khanna. (khannainstitute.com)
The NKCF is dedicated to increasing the awareness and understanding of keratoconus and the support of scientific research into the cause and treatment of keratoconus. (nkcf.org)

We describe the clinical and molecular genetic features of four inbred pedigrees from neighbouring remote villages in northern Pakistan, in which some of the affected members have concurrent keratoconus. (aku.edu)

Iatrogenic keratectasia after LASIK in a case of forme fruste keratoconus. (ijkecd.com)

FDACL provides a repeatable new procedure for determining disease severity in keratoconus. (wustl.edu)

There are few data in the literature on the long term stability of the refraction following PK for keratoconus. (bmj.com)

If you have been told that the only way to achieve good vision with keratoconus is with a corneal transplant, or if you've been told a corneal transplant is inevitable, question your eye doctor about options like scleral lenses. (nkcf.org)

Conclusions: The epithelial cells and keratocytes repopulated in the lenticules retain keratoconus-like biochemical abnormalities such as upregulation of Sp1 and downregulation of α1-PI and α2M. (johnshopkins.edu)

Keratoconus is differentiated into mild, moderate, and advanced cases. (medscape.com)

Like many ophthalmologists, he prefers the term highly asymmetric keratoconus as a more accurate description. (ophthalmologytimes.com)

Keratoconus traditionally was thought to be non-inflammatory, though recent studies have found inflammatory cytokines in the tear film. (medscape.com)

The Ophthalmologist, The Pathologist, and Journal of Nephrology. (medscape.com)

3, 4 Long term data on outcomes of PK for keratoconus tend to concentrate on survival rather than recording refractive outcomes. (bmj.com)

USH2A gene variants cause Keratoconus and Usher syndrome phenotypes in Pakistani families. (cdc.gov)

Anatomy3

Diseases4

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment10

Psychiatry and Psychology3

Phenomena and Processes2

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena2

Information Science11

Health Care3

Ophthalmology6

Ectasia17

Cornea10

Management of Keratoconus3

Cases of keratoconus3

Signs of keratoconus2

Keratoplasty8

Severe keratoconus2

Subclinical keratoconus3

Bilateral4

Patients32

Risk factors for keratoconus2

Family history of keratoconus6

Aberrations6

Development of keratoconus1

Ectatic corneal disorder1

Patient with keratoconus1

Corneas11

Scheimpflug7

Early keratoconus1

Refractive surgery9

Collagen4

Posterior6

Retrospective study1

Topography1

Corneal disease1

Intrastromal1

Pentacam1

Progressive6

METHODS1

Contact lenses1

Graft survival1

Pachymetry2

Susceptibility3

Eyes3

Treatment7

Clinical1

LASIK1

Severity1

Refraction1

Transplant1

Epithelial1

Mild1

Asymmetric1

Traditionally1

Ophthalmologist1

Outcomes1

Variants1