Homozygous familialFamilial hypercholesterolaemiaAmerican College ofRabbit model of hypercholesterolemiaHeterozygous familial hypercholesterolemiaHoFHHypertensionDensity lipoproteinAcquired and familialPatients with familialGeneticLipoproteinABSTRACTPrevalenceCoronary arteryHypothyroidismTendonDiagnosis2021StatinsHereditaryMutationsSevereResearchStudyMedicationPeer-reviewTreatmentEuropean JournalBiochemistryHighFindings2002ManagementInternational Journal
Homozygous familial7
- This is because patients with homozygous familial hypercholesterolemia (HoFH) lack functional LDL receptor activity and most of the current drugs work mainly through upregulation of LDL receptor in the liver. (ijpsr.com)
- A real-world experience of clinical, biochemical and genetic assessment of patients with homozygous familial hypercholesterolemia. (ijmedicine.com)
- Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. (ijmedicine.com)
- Palacio CH, Harring TR, Nguyen NT, Goss JA, O'Mahony CA. Homozygous familial hypercholesterolemia: case series and review of the literature. (ijmedicine.com)
- Mental health disturbances were found to be common in patients with homozygous familial hypercholesterolemia (HoFH), and the mental health status of these patients was found to be associated with lifestyle behaviors, according to a study published in the Journal of Clinical Lipidology . (thecardiologyadvisor.com)
- Mental status and physical activity in patients with homozygous familial hypercholesterolemia: A subgroup analysis of a nation-wide survey (A-HIT1 registry) [published online April 20, 2020]. (thecardiologyadvisor.com)
- Patients with homozygous familial hypercholesterolaemia (HoFH) have markedly elevated low density lipoprotein (LDL) cholesterol levels that are refractory to standard doses of lipid-lowering drug therapy. (elsevierpure.com)
Familial hypercholesterolaemia4
- Coronary heart disease, peripheral arterial disease, and stroke in familial hypercholesterolaemia: insights from the SAFEHEART registry. (ijmedicine.com)
- These drugs, as monotherapy or in combination with other lipid-lowering agents, represent an important therapeutic strategy in patients with high cardiovascular risk with severe familial hypercholesterolaemia or intolerance to statins. (bmj.com)
- Familial hypercholesterolaemia: identification and management. (bvsalud.org)
- This guideline covers identifying and managing familial hypercholesterolaemia (FH), a specific type of high cholesterol that runs in the family, in children, young people and adults. (bvsalud.org)
American College of1
- The AHA/ACC 2018 guideline on the management of blood cholesterol, endorsed by at least 10 other medical societies, is published today in the Journal of the American College of Cardiology and in Circulation to coincide with their grand unveiling at the AHA sessions. (medscape.com)
Rabbit model of hypercholesterolemia1
- The present study is aimed to investigate the effect of L-arginine (as a natural NO donor) supplementation on NO metabolite in a rabbit model of hypercholesterolemia to find a reliable marker for endothelial NO production. (ac.ir)
Heterozygous familial hypercholesterolemia2
- Measuring adherence with therapy for chronic diseases: Implications for the treatment of heterozygous familial hypercholesterolemia. (bvsalud.org)
- In a double-blind, randomized, placebo-controlled trial, Stein et al evaluated the efficacy and safety of add-on therapy with mipomersen, an apolipoprotein B synthesis inhibitor, in 124 patients with heterozygous familial hypercholesterolemia. (medscape.com)
HoFH1
- 1 Individuals with HoFH have marked hypercholesterolemia at birth. (acc.org)
Hypertension5
- Among males and females, self-reported hypertension and hypercholesterolaemia were significantly associated with MI and diabetes was a significant risk factor for women. (who.int)
- Selected households diabetes, hypertension, hypercholesterolemia, or were visited, and residents were given an initial eligibil- depression. (cdc.gov)
- JULY 2006 such as hypertension and hypercholesterolemia is poor (1-3). (cdc.gov)
- Une recherche documentaire a été effectuée dans PubMed de 1980 à 2021 en utilisant diverses combinaisons de termes MeSH comme tabac, diabète, hypertension, dyslipidémie, trouble dépressif majeur, trouble bipolaire, schizophrénie. (bvsalud.org)
- However, the proportion of patients having at least one metabolic complication of acromegaly at last follow-up (mean, 72 months after remission) was 27% for altered glucose tolerance or diabetes, 39% for hypertension, 34.3% for hypercholesterolemia, and 13.3% for hypertriglyceridemia. (medscape.com)
Density lipoprotein5
- Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels, specifically very high levels of low-density lipoprotein cholesterol (LDL cholesterol), in the blood and early cardiovascular diseases. (wikipedia.org)
- The aim of this study was to investigate whether consumption of a newly developed oat milk deprived of insoluble fiber would result in lower serum cholesterol and low-density lipoprotein (LDL) cholesterol levels in men with moderate hypercholesterolemia. (lu.se)
- Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by elevated low-density lipoprotein cholesterol (LDL-C), cholesterol deposition in the skin and tendons, and premature coronary heart disease. (acc.org)
- Familial hypercholesterolemia is a rare, monogenic, co-dominant, life-threatening disorder resulting from loss of function mutations in the genes responsible for synthesis of low-density lipoprotein receptors or apo-B genes or gain of function mutations in PCSK9 genes in the liver which affects 0.2% of the population. (ijmedicine.com)
- Familiar hypercholesterolemia (FH) is genetic disease that leads to increased serum low-density lipoprotein cholesterol (LDLc) and premature acute coronary syndromes (ACS). (fortunejournals.com)
Acquired and familial1
- Both acquired and familial hypercholesterolemia cause stress on the blood vessels and heart. (healthline.com)
Patients with familial1
- The guideline recommends PCSK9 inhibitors, whose randomized trial underpinnings were established after 2013, primarily for patients with familial hypercholesterolemia (FH), and for patients at very high ASCVD risk with elevated LDL-C despite maximal statins and ezetimibe. (medscape.com)
Genetic4
- A new study published in the US medical journal 'The Annals of Internal Medicine' makes a very strong case for universal genetic testing at the age of 30. (news-medical.net)
- Genetic identification of familial hypercholesterolemia within a single U.S. health care system. (nature.com)
- Genetic factors that lead to hypercholesterolemia have not been fully studied in India. (hindawi.com)
- Investigations of the genetic causes for this increased trend have been largely unexplored and the contribution of Familial Hypercholesterolemia (FH) is unknown. (hindawi.com)
Lipoprotein1
- Familial hypercholesterolemia (FH) is an autosomal-dominant condition that is characterized by elevated levels of plasma LDL cholesterol and apo-lipoprotein B resulting in an increased risk for atherosclerosis 1 . (ijpsr.com)
ABSTRACT2
- Abstract Background Most studies focused on the benefits of lycopene on serum lipids but no studies have been specifically designed to assess the role of a tomato sauce from vine-ripened tomatoes on patients affected by polygenic hypercholesterolemia. (researchgate.net)
- Each entry includes the title of the article, author(s), Journal title, year (date of publication), volume number, issue number, number of pages, number of references, subject descriptors, geographic descriptors and abstract has been added and is searchable on the database on the Internet. (who.int)
Prevalence2
- Data from the Orbital Study combined with the treated prevalence of hypercholesterolemia and the aging population in Germany project an estimated peak of costs for 2027, with a 15% increase up to that year, reaching a maximum of 15.5 billion Euros. (escardio.org)
- In the present analysis, we combine individual patient data from the ORBITAL study with the prevalence of treated hypercholesterolemia in Germany and demographic changes up to year 2050 in order to project future costs arising for this disease. (escardio.org)
Coronary artery1
- People with hypercholesterolemia have a high risk of developing a form of heart disease called coronary artery disease. (news-medical.net)
Hypothyroidism1
- Hypothyroidism and hypercholesterolemia were detected. (tubitak.gov.tr)
Tendon2
- Familial Hypercholesterolemia (FH) is an autosomal dominant disorder caused by mutation in the LDL receptor gene and characterized by raised LDL-C, tendon xanthomata and premature atherosclerosis. (ijpsr.com)
- In this study, we analyzed the consequences of hypercholesterolemia on the integrity of the collagen-based architecture of the Achilles tendon. (biomedcentral.com)
Diagnosis1
- A recent study published in the journal Scientific Reports assessed the associations between the change in total cholesterol (TC) levels after type 2 diabetes (T2D) diagnosis (relative to pre-diagnosis levels) and the risk of cardiovascular disease (CVD). (news-medical.net)
20212
- According to 2021 research , familial hypercholesterolemia is an inherited form of hypercholesterolemia where most individuals have high levels of cholesterol at birth. (healthline.com)
- As a result, all submissions received from December 07, 2021 are subject to an Article Publication Charge if accepted and published in the journal (unless a waiver is applied). (wiley.com)
Statins1
- also, had been diagnosed more often of hypercholesterolemia and had higher LDLc and statins treatments before admission. (fortunejournals.com)
Hereditary1
- Therefore, most people with hereditary hypercholesterolemia may have to use medications in addition to lifestyle changes to manage the condition. (healthline.com)
Mutations1
- Familial Hypercholesterolemia results from mutations in the LDL receptor, ApoB, PCSK9, and ApoE genes. (hindawi.com)
Severe1
- Severe primary hypercholesterolemia (LDL-C ≥190 mg/dL), often called FH. (medscape.com)
Research5
- Prior to assuming role of an Editor in Chief of Skin Research and Technology , Dr. Zemtsov was an Associate Editor and North American coeditor of this Journal. (wiley.com)
- Hungarian Educational Research Journal. (ntu.edu.sg)
- Editors select a small number of articles recently published in the journal that they believe will be particularly interesting to readers, or important in the respective research area. (mdpi.com)
- The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal. (mdpi.com)
- Familial hypercholesterolemia (FH) is an ideal candidate disease application for T4 translation research in genomic medicine. (cdc.gov)
Study2
- A total of 7640 patients with an indication for treatment of hypercholesterolemia according the European Guidelines on cardiovascular disease prevention in clinical practice were included in the ORBITAL study [2]. (escardio.org)
- Methods In this cross-over study, we evaluated a population of 108 ambulatory patients affected by polygenic hypercholesterolemia of both gender, who were allocated to a tomato sauce (namely OsteoCol) 150 ml/day or a sterol-enriched yogurt (containing sterols 1.6 g/die) treatment, for 6 weeks. (researchgate.net)
Medication1
- In patients with hypercholesterolemia, current guidelines recommend lifestyle interventions and, if necessary, medication to reduce high plasma cholesterol [2,3]. (escardio.org)
Peer-review2
- Fortune Journals follows a rigorous peer-review together with strict ethical policies and standards to ensure high quality scientific works to the field of scholarly publication. (fortunejournals.com)
- Fortune Journals follows single blind peer-review process, manuscript submitted by an Author is assigned to a particular Editor. (fortunejournals.com)
Treatment2
- Second, a rigorous, long-term monitoring and treatment of hypercholesterolemia and other risk factors, would also help to reduce the number of cardiovascular events. (escardio.org)
- carotenoid content may support treatment of patients affected by common hypercholesterolemia. (researchgate.net)
European Journal2
- European Journal of Training and Development. (ntu.edu.sg)
- Chemical characteristics of oils from naked and husk seeds of Cucurbita pepo L. European Journal of Lipid Science and Technology, 108(11), 936-943. (scielo.br)
Biochemistry1
- Journal of Nutritional Biochemistry, 13, 603-610. (scirp.org)
High2
- How is familial hypercholesterolemia different than nonheriditary high cholesterol? (healthline.com)
- Hypercholesterolemia is a condition characterized by very high levels of cholesterol in the blood. (news-medical.net)
Findings2
- The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
- Our findings support the hypothesis that hypercholesterolemia coincides with the weakening of the tendons. (biomedcentral.com)
20021
- RÉSUMÉ Cette étude, réalisée en mai 2002 dans le cadre de l'enquête nationale transversale à plusieurs degrés sur l'emploi et le chômage menée par le Département des Statistiques jordanien, a mesuré la prévalence de l'infarctus du myocarde (IDM) autodéclaré et son association à des facteurs de risque modifiables chez des sujets jordaniens âgés de 40 ans et plus. (who.int)
Management1
- Paez, KA & Allen, JK 2006, ' Cost-effectiveness of nurse practitioner management of hypercholesterolemia following coronary revascularization ', Journal of the American Academy of Nurse Practitioners , vol. 18, no. 9, pp. 436-444. (johnshopkins.edu)
International Journal3
- International Journal of Epidemiology. (monash.edu)
- International Journal of Obesity, 37, 576-583. (scirp.org)
- International Journal of Molecular Sciences. (helsinki.fi)