Purpose: While the elastin-specific crosslinks, desmosine and isodesmosine (DID), are increased in blood, urine, and sputum of patients with clinically documented pulmonary emphysema, the usefulness of DID in detecting early lung injury remains untested. (mssm.edu)
BiovaPlex is a natural joint health ingredient that contains collagens, elastin, hyaluronic acid, glucosamine, chon-droitin, and other glycosaminoglycans as well as growth factors and elastic peptides desmosine and isodesmosine. (agelesszenfab.com)
Collagen2
The development of atherosclerotic lesions and abdominal aortic aneurysms involves degradation and loss of extracellular matrix components, such as collagen and elastin. (harvard.edu)
PAIN FREE IN 5 DAYS: Thanks to a high concentration of water-soluble bioactive peptides such as collagen, elastin, desmosine, isodesmosine, glycosaminoglycans, and transforming growth factor, BiovaFlex® relieves pain faster than other eggshell membranes. (lawsons.ca)
Biomarkers2
These results support the exploration of free DES and IDE as biomarkers of elastin degradation. (harvard.edu)
These represent ideal biomarkers for monitoring elastin turnover because these special cross-links are only found in mature elastin in mammals. (wikipedia.org)
Amino2
Recombinant MMP-12 and neutrophil elastase liberated DES and IDE as amino acids from insoluble elastin. (harvard.edu)
Isodesmosine is an isomeric pyridinium-based amino acid resulting from the condensation of four lysine residues between elastin proteins by lysyl-oxidase. (wikipedia.org)