• Intramolecular lyases, oxidoreductases and transferases catalyze the interconversion of structural isomers. (wikipedia.org)
  • Although racemases and epimerases (EC 5.1) and cis-trans isomerases (EC 5.2) are sensibly grouped according to changes of stereochemistry, the overall chemistry of intramolecular oxidoreductases (EC 5.3), intramolecular transferases (EC 5.4) and intramolecular lyases (EC 5.5) is challenging. (researchgate.net)
  • Intramolecular Lyases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
  • This graph shows the total number of publications written about "Intramolecular Lyases" by people in this website by year, and whether "Intramolecular Lyases" was a major or minor topic of these publications. (ucdenver.edu)
  • Below are the most recent publications written about "Intramolecular Lyases" by people in Profiles. (ucdenver.edu)
  • Isomerases facilitate intramolecular rearrangements in which bonds are broken and formed. (wikipedia.org)
  • In addition, the separation of groups of isomerases sharing similar chemistry such as oxidosqualene cyclases and pseudouridine synthases from chemically complex sub-subclasses like intramolecular transferases acting on \other groups' (EC 5.4.99) might also improve the classification. (researchgate.net)
  • Isomerases, Intramolecular transferases (mutases), Transferring other groups. (uma.es)
  • A group of enzymes that catalyze an intramolecular transfer of a phosphate group. (lookformedical.com)
  • Transferases: catalyze the specific grouping transferring e.g. (researchwap.com)
  • Hepatic excretory capacity is low both because of low concentrations of the binding protein ligandin in the hepatocytes and because of low activity of glucuronyl transferase, the enzyme responsible for binding bilirubin to glucuronic acid, thus making bilirubin water soluble (conjugation). (medscape.com)
  • Conformationally Constrained Peptidomimetics as Inhibitors of the Protein Arginine Methyl Transferases. (gevers.eu)
  • Additionally, we highlight the development of new small molecule inhibitors to target parasite acyl transferases. (imperial.ac.uk)
  • Fecal specimens collected at baseline and at week 72 after treatment completion (FUw72) were analyzed for 16S rRNA sequencing and the butyryl-CoA:acetateCoA transferase (BCoAT) gene expression using real-time PCR. (bvsalud.org)
  • This mechanism is unprecedented in ADP-ribosyl transferase enzymology. (elsevierpure.com)
  • Spinelli, Domenico , Computational QM/MM Study of the Reaction Mechanism of Human Glutathione S-Transferase A3-3 , in: COMPUTATIONAL METHODS IN SCIENCE AND ENGINEERING: Theory and Computation: Old Problems and New Challenges. (unibo.it)
  • In this abortive ternary complex, CoA adopts a helical conformation with two intramolecular hydrogen bonds and the reactive sulfur of the pantetheine arm positioned 12 A away from the active site residues involved in the transferase reaction. (rcsb.org)
  • Next, water-soluble biliverdin is reduced to bilirubin, which, because of the intramolecular hydrogen bonds, is almost insoluble in water in its most common isomeric form (bilirubin IXα Z,Z). Because of its hydrophobic nature, unconjugated bilirubin is transported in the plasma tightly bound to albumin. (medscape.com)
  • HDM21-109 was made by PCR amplification of parental HDM2-pet22 plasmid using primers 28C29 followed by phosphorylation using T4 polynucleotide kinase and intramolecular ligation. (icem2012.org)
  • Lytic transglycosylases (LTs) catalyze the non-hydrolytic cleavage of the bacterial cell wall by an intramolecular transacetalization reaction. (nature.com)
  • Mct is a family III/Frc family CoA transferase that catalyzes an unprecedented intra-molecular CoA transfer from the C1-carboxyl group to the C4-carboxyl group of mesaconate at catalytic efficiencies >106 M-1 s-1. (bvsalud.org)
  • similar effects on phosphoribosyl-pyrophosphate amido transferase, orotidine-monophosphate decarboxylase, and both nucleoside and nucleotide kinases were observed. (nih.gov)
  • This fact supports the indication, derived from the similarity with chloramphenicol acetyl transferase, that the histidine side chain acts as general-base catalyst in the deprotonation of the reactive thiol of CoA. (rcsb.org)
  • The deprotonated glutamate/aspartate then acts as a general base to activate the C6-OH for intramolecular attack at the anomeric carbon. (nature.com)