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InteractionsDosageIncreasesMedicationExacerbateOral AdministrationAvoidAbsorptionTypeListEffectsPrescriptionSpecificTreatmentRiskPatients
Interactions1
Dosage1
  • Therapy with carbidopa, given with or without levodopa or carbidopa-levodopa combination products, is started, dosage adjustment of the antihypertensive drug may be required. (medscape.com)
Increases2
  • aldesleukin increases effects of minoxidil by pharmacodynamic synergism. (medscape.com)
  • Observational studies have demonstrated that concomitant use of opioid analgesics and benzodiazepines increases the risk of drug-related mortality compared to the use of opioids alone. (pdr.net)
Medication1
  • Duration of separation may depend on the absorption of the medication concomitantly administered (eg, time to peak concentration, whether the drug is an immediate or extended release product). (medscape.com)
Exacerbate2
  • Use triazolam with caution in individuals with significant pulmonary disease or respiratory insufficiency, such as chronic obstructive pulmonary disease (COPD) or sleep apnea because the drug can exacerbate respiratory depression. (pdr.net)
  • Mefenamic acid, like all nonsteroidal anti-inflammatory drugs (NSAIDs), may exacerbate hypertension and congestive heart failure and may cause an increased risk of serious cardiovascular thromboembolism, myocardial infarction, and stroke, which can be fatal. (pdr.net)
Oral Administration1
Avoid3
  • Avoid or Use Alternate Drug. (medscape.com)
  • Avoid use when taking any oral drug that is dependent on threshold concentrations for efficacy. (medscape.com)
  • Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension. (medscape.com)
Absorption1
  • Following epidural administration, systemic absorption and absorption into the intrathecal space via the meninges occurs. (unboundmedicine.com)
Type2
  • Aldesleukin treats kidney cancer and a certain type of skin cancer. (rxwiki.com)
  • Aldesleukin is a type of drug known as biosynthetic interleukin-2. (rxwiki.com)
List1
  • This is not a complete list of aldesleukin side effects. (rxwiki.com)
Effects3
  • For oral drugs where reductions in bioavailability may cause clinically significant effects on its safety or efficacy, separate administration of ferric maltol from these drugs. (medscape.com)
  • Did you experience many side effects while taking this drug? (rxwiki.com)
  • Aldesleukin can cause serious side effects. (rxwiki.com)
Prescription1
  • Aldesleukin is a prescription medicine used to treat kidney cancer that has spread, known as metastatic renal cell carcinoma (metastatic RCC). (rxwiki.com)
Specific1
  • In the case of aldesleukin there are no specific foods that you must exclude from your diet when receiving aldesleukin. (rxwiki.com)
Treatment2
  • Aldesleukin is used for the treatment of adults with metastatic renal cell carcinoma (metastatic RCC). (rxwiki.com)
  • Reserve concomitant prescribing of these drugs for when alternative treatment options are inadequate. (pdr.net)
Risk1
  • Methods Survival of 810 mRCC patients treated from 2006 to 2017 with high dose IL-2 (aldesleukin) and enrolled in the PROCLAIM SM registry data base was assessed utilizing the International Metastatic RCC Database Consortium (IMDC) risk criteria. (bmj.com)
Patients2
  • Assess patients for risks of addiction, abuse, or misuse before drug initiation, and monitor patients who receive benzodiazepines routinely for development of these behaviors or conditions. (pdr.net)
  • To discourage abuse, the smallest appropriate quantity of the benzodiazepine should be prescribed, and proper disposal instructions for unused drug should be given to patients. (pdr.net)