AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyInformation Science
Cyproterone AcetateCyproteroneAndrogen AntagonistsEthinyl EstradiolHirsutismEstradiol CongenersChlormadinone AcetateTestosteroneTranssexualismAcne VulgarisDihydrotestosteroneOcimumAndrogensAcetatesPuberty, PrecociousPregnanesProgesterone CongenersFlutamidePolycystic Ovary SyndromeCastrationProstateMetriboloneReceptors, AndrogenImidazolidinesBuserelinSeminal VesiclesGoserelinPregnadienesGenitalia, MaleTosyl CompoundsEncyclopedias as Topic
High dose cyproteroneSynthetic progestogenEthinylestradiolAbiraterone acetateAntiandrogensDiane 35 TabletEthinylTabletsMeningioma associatedAcneCapsulesAntiandrogenCumulative doseLevonorgestrelContraceptivesHyperandrogenismMedicationsClinicalTreatmentActiveWomenYearsEffectiveWorkAdditionalGroupMedicineRiskPack
High dose cyproterone3
  • Objective To assess the risk of meningioma associated with use of high dose cyproterone acetate, a progestogen indicated for clinical hyperandrogenism. (bmj.com)
  • Participants had at least one reimbursement for high dose cyproterone acetate and no history of meningioma or benign brain tumour, or long term disease status. (bmj.com)
  • sometimes fatal, developing usually after several months of high-dose cyproterone therapy, but an association with liver cancer is uncertain. (pocketdrugguide.com)
Synthetic progestogen2
  • Cyproterone acetate is a synthetic progestogen with a potent antiandrogen action. (bmj.com)
  • The aim of this work was to assess whether cyproterone acetate, a synthetic progestogen, can prevent this flare-up effect. (frontiersin.org)
Ethinylestradiol5
  • Cyproterone acetate + Ethinylestradiol (Althea ® ) is indicated for contraception in women, and control of acne and hirsutism (unwanted hair growth). (easyreach.ph)
  • When low-dose cyproterone is given with ethinylestradiol to women, adverse effects associated with combined oral contraceptives may occur. (pocketdrugguide.com)
  • In 2002, the UK CSM warned that preparations containing cyproterone and ethinylestradiol should not be used solely for contraception, but for treatment of severe acne that had not responded to oral antibac-terials, or for moderately severe hirsutism, and that they should be withdrawn 3 or 4 cycles after the treated condition has completely resolved. (pocketdrugguide.com)
  • In 2008, the CHM (formerly the CSM) reconfirmed its 2002 advice on the use of cyproterone with ethinylestradiol. (pocketdrugguide.com)
  • The study of any association may be confounded by the adverse cardiovascular risk associated with polycystic ovary disease, an underlying condition in many women given cyproterone with ethinylestradiol to manage acne and hirsutism. (pocketdrugguide.com)
Abiraterone acetate3
  • The most common methods of androgen deprivation therapy currently employed to treat prostate cancer are castration (with a GnRH modulator or orchiectomy), nonsteroidal antiandrogens, and the androgen synthesis inhibitor abiraterone acetate. (wikipedia.org)
  • Enzalutamide, apalutamide, and abiraterone acetate are specifically approved for use in combination with castration to treat castration-resistant prostate cancer. (wikipedia.org)
  • In addition, newer and more effective antiandrogens like abiraterone acetate (Zytiga) in 2011 and enzalutamide (Xtandi) in 2012 were introduced and superseded bicalutamide as the standard-of-care antiandrogen for the treatment of prostate cancer. (transfemscience.org)
Antiandrogens3
  • Bicalutamide could eventually come to be regarded as acceptably safe for use in transfeminine hormone therapy, similarly to other antiandrogens with rare risks like spironolactone and cyproterone acetate. (transfemscience.org)
  • Bicalutamide has major advantages over other antiandrogens such as spironolactone (Aldactone) and cyproterone acetate (Androcur) in terms of antiandrogenic potency , clinical effectiveness , pharmacological selectivity , and tolerability . (transfemscience.org)
  • Cyproterone belongs to a group of medications known as antiandrogens. (alldaygeneric.com)
Diane 35 Tablet1
Ethinyl5
Tablets2
Meningioma associated1
Acne2
  • Some have also called for the removal of the CSM recommendation to limit the duration of therapy, particularly as acne and hirsutism frequently recur after stopping cyproterone therapy. (pocketdrugguide.com)
  • Cyproterone works by blocking the Extra production of androgens (male hormones) in the ovaries, thereby decreasing hated hair growth and acne. (alldaygeneric.com)
Capsules1
  • All subjects received a 4.7 mg deslorelin implant by SC route and 1-3 capsules containing either cyproterone acetate 2 mg/kg ( N = 9) or a placebo ( N = 9), by oral route BID for 14 days, depending on the dog's weight. (frontiersin.org)
Antiandrogen1
  • Cyproterone acetate acts as an antiandrogen by blocking androgen receptors. (rxreasoner.com)
Cumulative dose3
  • The adjusted hazard ratio for a cumulative dose of cyproterone acetate of more than 60 g was 21.7 (10.8 to 43.5). (bmj.com)
  • In a complementary analysis, 463 women with meningioma were observed among 123 997 already using cyproterone acetate in 2006 (risk of 383 per 100 000 person years in the group with the highest exposure in terms of cumulative dose). (bmj.com)
  • The higher the cumulative dose and the longer the treatment duration, the bigger the risk of meningioma (12-fold after 5 years of treatment for nomegestrol acetate, and 7-fold after 3.5 years of treatment for chlormadinone acetate). (bvsalud.org)
Levonorgestrel2
  • A case-control study suggested that the risk of venous thrombo embolism may be further increased for women taking combined contraceptives containing cyproterone compared with levonorgestrel. (pocketdrugguide.com)
  • However, others' have questioned some study results, concluding that preparations containing cyproterone are not associated with a risk in excess of that associated with conventional combined oral contraceptives including those containing levonorgestrel. (pocketdrugguide.com)
Contraceptives1
  • Un échantillon de 150 agents de soins de santé dans des maisons de santé et de 150 pharmaciens en milieu hospitalier ou communautaire ont répondu au questionnaire évaluant leurs connaissances sur l'utilisation correcte des pilules contraceptives, les effets secondaires, les contre-indications, les signes de danger/symptômes et les avantages non-contraceptifs, mais aussi sur l'offre ou non de conseils aux patientes en la matière. (who.int)
Hyperandrogenism1
  • Any neoplasm origin can be thought in case of current start of hyperandrogenism, that is swiftly accelerating sufficient reason for indications of virilization. (cxcr-signal.com)
Medications2
  • The absence of an indication or treatment should not roule out the existence of other appropriate medications. (rxreasoner.com)
  • Nevertheless, these medications have many indications that demonstrate their importance in the daily practice of the general practitioner, of the gynecologist and of the reproductive endocrinologist. (bvsalud.org)
Clinical1
  • Clinical Examples for Various Clinical Indications and Pathologies 3D CE MRA is capable optioj displaying the main vis- ceral vessels with excellent diagnostic accuracy. (forextrading-madeeasy.com)
Treatment4
  • There may be azoospermia after 8 weeks and slight atrophy of the seminiferous tubules, but these changes are slowly reversible and spermatogenesis usually recovers to pre-treatment levels about 3 to 5 months after stopping cyproterone. (pocketdrugguide.com)
  • The duration of cyproterone acetate treatment should be defined on an individual basis. (rxreasoner.com)
  • A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. (rxreasoner.com)
  • Cyproterone acetate could be the best-known and a lot efficient antiandrogenic treatment. (cxcr-signal.com)
Active1
  • Cervical vertebrae 1,2, …?Ca: Calcium?Ca: Cancer?Ca: Carcinoma?Ca: Cardiac arrest?Ca: Coronary artery?CA-125: A tumor marker for ovarian cancer?CAB: Cellulose acetate butyrate?CABG: Coronary artery bypass graft?CACI: Computer-Assisted Continuous Infusion?CAD: Coronary artery disease?CAG: ?CAH: Chronic active hepatitis?CAH: Congenital adrenal hyperplasia?calid. (kuwaitpharmacy.com)
Women1
  • Participants 253 777 girls and women aged 7-70 years living in France who started cyproterone acetate between 2007 and 2014. (bmj.com)
Years1
Effective1
Work1
  • Continuous work is underway to provide more substance documents with this type of environmental information and also present comparisons of environmental risk between substances intended for the same indication. (janusinfo.se)
Additional1
Group1
  • After discontinuation of cyproterone acetate for one year, the risk of meningioma in the exposed group was 1.8-fold higher (1.0 to 3.2) than in the control group. (bmj.com)
Medicine1
  • Diane 35(Cyproterone acetate) is a medicine which falls into the category of anti-androgen, which necessarily means it reduces the action of male sex hormones known as androgen and hence reduces the production of the same. (alldaygeneric.com)
Risk1
  • Conclusions A strong dose-effect relation was observed between use of cyproterone acetate and risk of intracranial meningiomas. (bmj.com)
Pack1
  • 99.75 % ) 13 2 propanol ip: 45 g / isopropanol, 1 propanol: 30 g / n propanol ethyl hexadecyl dimethyl ammonium ethylsulphate: 0.2 g emollient and moisturiser with skin protecting substances 500 ml bott with dispenser passes en 13727, en13624, en14476, en1500, en12791 standards, pack size: 500 ml bottle 14 4 methylumbelliferone ( 100gm ) ( purity ( hplc ) =98 %, mol. (jharkhandtenders.net)