Immunologic factors. Medical search. Frequent questions

BAFF is the natural ligand of three nonconventional tumor necrosis factor receptors named BAFF-R (BR3), TACI (transmembrane activator and calcium modulator and cyclophilin ligand interactor), and BCMA (B-cell maturation antigen), all of which have differing binding affinities for it. (wikipedia.org)
[4] BAFF is the natural ligand of three unusual tumor necrosis factor receptors named BAFF-R (BR3), TACI (transmembrane activator and calcium modulator and cyclophilin ligand interactor), and BCMA (B-cell maturation antigen), all of which have differing binding affinities for it. (wikidoc.org)
Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP. LP is a T-cell mediated immunologic disease but the responsible antigen remains unidentified. (hindawi.com)
The detection of anti-HBs is indicative of a prior immunologic exposure to the antigen or vaccine. (cdc.gov)
Anaphylaxis is a systemic, immediate hypersensitivity reaction mediated by factors released from interactions between immunoglobulin E (IgE) and mast cells that produce an antigen-antibody reaction. (cancernetwork.com)
Factor XIIIa and factor XIIIb antigen levels can be quantified by means of enzyme-linked immunosorbent assay (ELISA). (medscape.com)

B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B and CD257 among other names, is a protein that in humans is encoded by the TNFSF13B gene. (wikipedia.org)
Detection in the 1970s of a related orthopoxvirus that causes monkeypox, a similar but milder illness in humans that can be fatal in up to 10 percent of patients, raised concerns that this virus may replace the ecologic and immunologic niche created by the eradication of smallpox. (cdc.gov)

BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. (wikipedia.org)
This study aimed to elucidate the relationship between local and systemic inflammation in smoking-induced COPD by assessing levels of soluble (s) tumor necrosis factor (TNF) receptors, TNF-alpha, and interleukin-8 (IL-8) in induced sputum and in plasma. (nih.gov)
Nerve cells do so by releasing neuromediators such as substance P (SP), which acts on both the vascular bed to cause vasodilation and increase permeability, and on skin cells to promote the release of pro-inflammatory cytokines including some interleukins (IL-1 and IL-8) and tumor necrosis factor-alpha (TNF-α). (cosmeticsandtoiletries.com)

The pathophysiology of atopic dermatitis is complex and involves genetic factors, epidermal barrier dysfunction, immunologic mechanisms, and environmental triggers. (medpagetoday.com)
Etiologies include immunologic and genetic factors. (definitions.net)

The underlying mechanisms do not appear to be primary immunologic or allergic in nature. (cosmeticsandtoiletries.com)

Borrelia peptidoglycan interacting Protein (BpiP) contributes to the fitness of Borrelia burgdorferi against host-derived factors and influences virulence in mouse models of Lyme disease. (ouhsc.edu)

epidemiology and phenotypic, immunologic and molecular diagnostic methods. (elsevier.es)

The subset of patients with anti-Ro/La antibodies had the highest prevalence of most systemic, hematologic, and immunologic alterations (higher frequency of Raynaud phenomenon, altered parotid scintigraphy, positive salivary gland biopsy, peripheral neuropathy, thrombocytopenia, and rheumatoid factor). (nih.gov)
Specific antibodies to the low ionic strength components inhibited factor VIII activity in normal plasma, but the residual factor VIII was higher than that after inhibition with antibodies against intact factor VIII. (ashpublications.org)
Both antibodies interfered with von Willebrand factor activity. (ashpublications.org)
These findings will make it possible to more accurately select candidates for the different clinical trials in progress to assess the utility of treatment with interferon or blockers of these antibodies, aimed at counteracting the consequences of these genetic and immunologic factors involved in some severe forms of COVID-19", said Dr. Aguilera. (navarrabiomed.es)
One category of immunologic problems that can cause miscarriages are the antiphospholipid antibodies . (resolve.org)

Factors like brain-gut axis interactions, immunologic disturbances, oxidative stress, and vagus nerve dysfunction can cause inflammatory bowel disease and mental disorders. (psychiatrist.com)

Is there an immunologic reaction? (harvard.edu)
What initiates the autoimmune reaction in Crohn's disease is unclear, but genetic and environmental factors play roles. (hdkino.org)
The explant-mixed epidermal lymphocyte reaction system gave consistent, reproducible results and may prove useful for the allocation of an immune protection factor to all sunscreens. (bentham.co.uk)
The 2 methods used to measure the enzymatic activity of factor XIII include measurement of synthetic amine incorporation into a fibrin clot, and measurement of ammonium ion release during the transglutaminase reaction. (medscape.com)

Objective: To investigate the effects of TH9507, a novel growth hormone releasing factor, on abdominal fat accumulation, metabolic and safety parameters in HIV-infected patients with central fat accumulation. (natap.org)
Secondary endpoints included change in insulin-like growth factor-I (IGF-I), metabolic, quality of life, and safety parameters. (natap.org)
Data collected during the pandemic suggest that COVID-19 may determine acute detrimental immunologic, metabolic, and thromboembolic abnormalities. (springer.com)

Hypocomplementemia was associated with a higher frequency of vasculitis and lymphoma, and cryoglobulins with a higher frequency of parotid enlargement, vasculitis, and leukopenia.Epidemiologic, clinical, and analytical features have a significant impact on the clinical presentation of primary SS, influencing the results of the main diagnostic tests, the prevalence and diversity of extraglandular involvement, and the frequency of the main immunologic markers. (nih.gov)
Better demand for diagnostic procedures, policy coverage, high-level of awareness, and others are some of the significant factors that can inspire the market growth. (medgadget.com)

Exposure of skin to sunlight also depends on multiple lifestyle factors (eg, clothing, occupation, recreational activities). (msdmanuals.com)

The international collaborative study COVID Human Genetic Effort (COVIDHGE), in which the Hospital Complex of Navarre (CHN) and the Navarrabiomed Clinical Trials Platform took part, has shown that genetic and immunologic factors that affect the severity of the disease are found in approximately 15% of severe cases of COVID-19. (navarrabiomed.es)
Abnormality in this molecule is due to genetic or immunologic factors that prevent the body's cells from defending themselves against the coronavirus, which may leave the patient in a severe clinical condition. (navarrabiomed.es)
Methods In this study we describe treatment interruption patterns over time among clients who interrupt and subsequently resume HAART, and those who are continuously engaged in treatment, and determine clinical factors associated with loss to engagement.An observational, longitudinal, retrospective cohort design was engaged, using secondary treatment program data. (researchgate.net)
Delayed umbilical bleeding--a presenting feature for factor XIII deficiency: clinical features, genetics, and management. (medscape.com)

Furthermore, long-term persistence of neurologic and neuropsychiatric manifestations was also described in COVID-19 survivors [ 5 ] and was associated with pro-inflammatory unbalance [ 6 ], suggesting that such immunologic changes may persist long after the resolution of the infection. (springer.com)

Rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) antibody are usually negative. (unboundmedicine.com)

Demographic, ecological, and politico-economic factors together with comorbidities have influenced the severity of Coronavirus disease 2019 (COVID-19) worldwide [ 1 ]. (springer.com)

The results recently published in two articles in the journal Science partially solve the mystery of why some young, healthy people suffer severe COVID-19 by linking incidence to genetic and immunologic factors. (navarrabiomed.es)

We conducted a population-based, frequency-matched case-control study in Sicily to further investigate the reported inverse relationship between smoking and classical Kaposi sarcoma and to identify other factors associated with altered risk. (aacrjournals.org)
Identify key concepts of the immunologic and neuropathologic disease processes associated with multiple sclerosis. (hcplive.com)

Dialysis of factor VIII against buffers of low ionic strength led, however, to a decrease in factor VIII procoagulant activity and the reduction of the correcting activities, which suggested that the intact aggregate was required for procoagulant activity and for von Willebrand factor activity. (ashpublications.org)

Since dialysis of human factor VIII against buffers of low ionic strength yielded two distinct components, and since the factor VIII fraction isolated from normal plasma showed von Willebrand factor activity as defined by the corrective effect on abnormal platelet retention and ristocetin aggregation in von Willebrand's disease, the present studies were performed to determine if the correcting activities could be attributed to one or both of the components. (ashpublications.org)
The exact cause of pediatric Crohn's disease is not fully understood, but this is thought to develop because of multiple different factors occurring together including genetic, immunologic and environmental triggers. (rarediseases.org)
Immunologic and inflammatory diseases contribute to the progression of the disease. (emedicinehealth.com)

B-lymphocytes may propagate demyelination and neurodegeneration, most likely by producing soluble neurotoxic factors. (frontiersin.org)

Cartilage destruction is a result of several mechanical and biological factors rather than a single entity. (emedicinehealth.com)

Young-onset patients had a low degree of sicca involvement (xerostomia and parotid enlargement) and a high frequency of immunologic markers (anti-Ro/SS-A and low C4 levels). (nih.gov)
Clarify the appropriate use of immunologic (CD4 count) monitoring in the care of patients with HIV. (hivguidelines.org)

The identified transcription factors influence both the global and specific gene expression of the BCLs and have possible implications for diagnosis and treat- ment. (lu.se)

A quantitative assay is required to confirm the diagnosis of factor XIII deficiency. (medscape.com)
Problems relating to the laboratory diagnosis of factor XIII deficiency: a UK NEQAS study. (medscape.com)

Immunologic Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)

Precipitating factors include herpes simplex virus (HSV), Epstein-Barr virus (EBV), and histoplasmosis. (medscape.com)

Ichinose A. Physiopathology and regulation of factor XIII. (medscape.com)

These factors can result in admission to the ICU and even death. (navarrabiomed.es)
however, it is thought to be the result of a combination of genetic and immunologic factors. (psychiatrist.com)

In contrast, higher number of cohabitants (OR 1.26, p = 0.02) and works requiring direct external contact (OR 2.61, p = 0.0002) or in the healthcare sector (OR 3.73, p = 0.0019) resulted risk factors for COVID-19. (springer.com)
At the end of follow-up, the hazard of unfavorable treatment outcome (dead, lost, stopped HAART) for clients who restarted treatment at months 6, 12, 18 and 24 was higher by a factor of 1.9, 2.4, 2.6 and 2.4, as compared to those who never discontinued treatment at those times. (researchgate.net)

However, risk factors for post-vaccination fatal COVID-19 are largely unknown. (nature.com)
As this frightening pandemic has spread rapidly throughout the world, the sometimes contradictory reports of its manifestations should be understood in the context of the heterogeneous populations that have been infected, and the immense spectrum of genetic predispositions, coexisting risk factors and pre-existing medications that can hinder cohesive understanding. (nature.com)
We assessed modifiable risk factors associated with COVID-19 in PwMS. (springer.com)
In fact, recent or recurrent herpes has been reported as the principle risk factor for erythema multiforme. (medscape.com)
And those in purple are recommended for adults with additional risk factors or another indication. (cdc.gov)

Ichinose A, Asahina T, Kobayashi T. Congenital blood coagulation factor XIII deficiency and perinatal management. (medscape.com)

Testing for anti-HBs can be useful for: a) evaluating the recovery and prognosis of patents infected with HBV, b) screening for potential vaccine recipients, and c) epidemiologic factors associated with transmission of HBV. (cdc.gov)

The two low ionic strength components were identified by the use of a rabbit antiserum against factor VIII, and could be distinguished on the basis of specific antigenic structures. (ashpublications.org)

Another category of immunologic causes of miscarriage are those that prevent the woman's normal protective response to the embryo. (resolve.org)
Results from standard hemostatic screening tests such as activated partial thromboplastin time (aPTT) and international normalized ratio (INR) assessments are normal in factor XIII (FXIII) deficiency. (medscape.com)

0.0001) emerged as protective factors against COVID-19. (springer.com)
Several studies have suggested a lack of correlation between sunscreen sun protection factor and protection of skin immune system, potentially allowing greater damage to the skin by removing the natural protective erythemal response to sun exposure. (bentham.co.uk)

Additional studies have revealed a broad anti-inflammatory effect of α-MSH apparently mediated by a modulation of nuclear factor κ-β activity (NF-κβ). (cosmeticsandtoiletries.com)

This graph shows the total number of publications written about "Immunologic Factors" by people in this website by year, and whether "Immunologic Factors" was a major or minor topic of these publications. (ouhsc.edu)

Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms. (medscape.com)

B-cell activating factor has been shown to interact with TNFRSF13B, TNFSF13, TNFRSF13C, and TNFRSF17. (wikipedia.org)

however, factor XIII levels as low as 1-3% may be sufficient to crosslink the fibrin, stabilizing the clot. (medscape.com)

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