Von Hippel-Lindau Tumor Suppressor Proteinvon Hippel-Lindau DiseasePancreatic CystHypoxia-Inducible Factor 1, alpha SubunitKidney NeoplasmsCarcinoma, Renal CellProcollagen-Proline DioxygenaseTumor Suppressor Protein p53Nobel PrizeUbiquitin-Protein LigasesTumor Suppressor ProteinsGenes, Tumor SuppressorHemangioblastomaCell HypoxiaRho FactorTumor Suppressor Protein p14ARFRetinoblastoma ProteinCell Line, TumorProto-Oncogene Proteins c-mdm2von Willebrand FactorMutationGenes, p53Nuclear ProteinsMolecular Sequence DataAnoxiaApoptosisGene Expression Regulation, NeoplasticProtein BindingNeurofibromin 2DNA-Binding ProteinsTranscription FactorsTransfectionAdenomatous Polyposis Coli ProteinCell LineCell CycleTumor Cells, CulturedCyclin-Dependent Kinase Inhibitor p16Genes, SuppressorProto-Oncogene ProteinsSignal TransductionPTEN PhosphohydrolasePromoter Regions, GeneticCyclin-Dependent Kinase Inhibitor p21Base SequenceCell Cycle ProteinsAmino Acid SequenceCell ProliferationCell Transformation, NeoplasticLigasesPhosphorylationNeoplasmsRNA, MessengerDNA DamageTranscription, GeneticCell DivisionNeoplasm ProteinsCyclinsBlotting, WesternDown-RegulationE2F Transcription Factorsvon Willebrand DiseasesTranscriptional ActivationRepressor ProteinsProteinsProtein Structure, TertiaryTumor Markers, BiologicalCells, CulturedGene SilencingBinding SitesGene Expression RegulationReverse Transcriptase Polymerase Chain ReactionE2F1 Transcription FactorProtein-Serine-Threonine KinasesRNA InterferenceCarrier ProteinsSuppressor of Cytokine Signaling ProteinsRNA, Small InterferingFibroblastsHeLa CellsDNA MethylationLoss of HeterozygosityTranscription Factor DP1Recombinant Fusion ProteinsSuppression, GeneticHypoxia-Inducible Factor 1Oncogene Proteins, ViralPapillomavirus E7 ProteinsGene DeletionWT1 ProteinsTumor BurdenCell NucleusRetinoblastoma-Binding Protein 1ImmunohistochemistryTrans-ActivatorsTumor Necrosis Factor-alphaDNA PrimersRetinoblastoma-Like Protein p107