• obesity
  • According to guidelines from the World Health Organization (WHO), overweight in adults is defined by body mass index (BMI) of 25.0 to 29.9, and obesity is defined by a BMI of 30.0 or higher [ 7 ]. (hindawi.com)
  • hypertension
  • Thiazide (/ˈθaɪəzaɪd/) is a type of molecule and a class of diuretics often used to treat hypertension (high blood pressure) and edema (such as that caused by heart failure, liver failure, or kidney failure). (wikipedia.org)
  • However, the recent 2011 UK National Institute for Health and Clinical Excellence (NICE) guideline on the management of primary hypertension in adults (CG127) recommend calcium channel blockers (CCBs) as first line agents in hypertension and advise that thiazide-like diuretics should only be used first line if CCBs are not suitable or if the patient has oedema or has a high risk of developing heart failure. (wikipedia.org)
  • mice
  • C57BL/6 male mice were divided in two groups according to their diet for 8 weeks: standard diet (ST) and high-fat diet (HF). (hindawi.com)
  • Its role in liver steatosis is well established, since mice with liver-specific deletion of PGC-1α exhibit lipid accumulation and high-fat diet reduces hepatic PGC-1α expression in mice. (springer.com)
  • C57black/6 mice were fed a high-fat diet containing 30% fat for 10 weeks. (springer.com)
  • Glucose elimination after an intravenous glucose challenge (1 g/kg) was significantly delayed after 1, 4, and 8 weeks on the high-fat diet compared with normal-diet-fed mice. (diabetesjournals.org)
  • In contrast, the early islet changes after feeding these mice a high-fat diet are less well studied. (diabetesjournals.org)
  • Finally, we also examined the expression of the functional full-length leptin receptor (ObRb) because β-cells express this receptor ( 15 ), and circulating leptin is increased in high-fat-fed mice ( 4 , 16 , 17 ). (diabetesjournals.org)
  • PPARG knockout mice fail to generate adipose tissue when fed a high-fat diet. (wikipedia.org)
  • mild
  • In patients with glycogen-storage disease type 0, hyperlipidemia is absent or mild and proportional to the degree of fasting. (wikipedia.org)
  • The following characteristics suggest the possibility of a diagnosis of MODY in hyperglycemic and diabetic patients: Mild to moderate hyperglycemia (typically 130-250 mg/dl, or 7-14 mmol/l) discovered before 30 years of age. (wikipedia.org)
  • abnormalities
  • Some forms of primary hypertriglyceridemia can lead to specific symptoms: both familial chylomicronemia and primary mixed hyperlipidemia include skin symptoms (eruptive xanthoma), eye abnormalities (lipemia retinalis), hepatosplenomegaly (enlargement of the liver and spleen), and neurological symptoms. (wikipedia.org)
  • nuclear translocation
  • However, the nuclear translocation of the homeobox transcription factor, pdx-1, and the plasma membrane translocation of GLUT2 were both impaired in high-fat-fed animals after 1 week. (diabetesjournals.org)
  • inflammation
  • High-fat diet induces liver inflammation by inhibiting PGC-1α expression and its suppressive effect in NFκB pathway. (springer.com)
  • diseases
  • Changes in lifestyle such as increase in high-fat food consumption are an important cause for vascular diseases. (hindawi.com)
  • diet
  • Recent evidences suggest that high fat diet, which is also characteristic of cafeteria type diet, as well as sedentary life style are two contributory factors for increased trends of obese people among the nations [ 5 ]. (hindawi.com)
  • The present study aimed to investigate the involvement of ACE and TGF- β in the aorta stiffness induced by high-fat diet. (hindawi.com)
  • The high-fat diet led to a state of nonalcoholic steatohepatitis, associated with increased deposits of intra-abdominal fat, hyperglycemia and hyperlipidemia. (springer.com)
  • Animals were divided into two groups, receiving either standard rodent food or a high-fat diet (diet nos. (diabetesjournals.org)
  • On a caloric base, the high-fat diet consisted of 16.4% protein, 25.6% carbohydrates, and 58.0% fat, which corresponds to an energy content of 23.6 kJ/g. (diabetesjournals.org)
  • Patients
  • Patients with glycogen-storage disease type 0 have normal-to-increased response to glucagon in the fed state, with hyperglycemia and lactic acidemia. (wikipedia.org)
  • effects
  • Since CCK inhibits food intake and reduces appetite, this provides another mechanistic explanation for the satiety promoting effects of high protein intakes. (blogspot.com)
  • Values
  • And the corrected energy content per 100g of almonds is 456kcal/100g not 575kcal/100g (nutritiondata.com), or even higher values you will find when you google "almonds kcal" - I am curious if at least the nutrition labes will ever be updated. (blogspot.com)