• Obesity is considered a clinical state of impaired general heath in which the excessive increase in adipose tissue mass may be associated with metabolic disorders such as type 2 diabetes mellitus, hyperlipidemia, hypertension and cardiovascular diseases. (uzh.ch)
  • The comprehensive list comprised an array of well-known threats including non-communicable diseases such as cancer, type-2-diabetes, cardiovascular disease, and stroke, as well as emerging threats such as antimicrobial resistance. (news-medical.net)
  • Raman spectroscopy has slipped into biomedical science proving its utility in medical diagnostics for diseases as diverse as cancer, cardiovascular disease and bacterial infections. (news-medical.net)
  • Numerous scientific studies have also shown that chronic exposure to these particles increases the risk of developing cardiovascular and respiratory diseases. (occe.eu)
  • Mitochondrial dysfunction has been proven to play a critical role in the pathogenesis of cardiovascular diseases. (frontiersin.org)
  • We hope this review will provide perspectives on mitochondrial-targeted therapeutics in cardiovascular diseases. (frontiersin.org)
  • The abnormal morphology and dysfunction of mitochondria have been proven as the principal mechanisms in the pathogenesis of cardiovascular diseases, such as heart failure, myocardial infarction, atherosclerosis, and hypertension ( 4 - 6 ). (frontiersin.org)
  • So mitochondria-targeted therapy is suggested to be a potential treatment strategy for cardiovascular diseases. (frontiersin.org)
  • However, clinical trials of these agents for cardiovascular diseases were hardly approved to carry out, even less to evaluate their clinical effectiveness and safety. (frontiersin.org)
  • Therefore, patients with cardiovascular diseases would fail to achieve the desired outcomes by using these mitochondrial-targeted drugs ( 5 ). (frontiersin.org)
  • The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. (oatext.com)
  • 2. One of the reasons for increased cardiovascular diseases (CVDs) worldwide is the increase in aged populations. (who.int)
  • The most important cardiovascular diseases (CVDs) in the African Region are those related to atherosclerosis, cardiomyopathies and rheumatic heart disease. (who.int)
  • 5. The WHO STEPwise approach to surveillance of noncommunicable diseases in general and cardiovascular disease in particular (otherwise known as STEPS) is based on community evaluation of eight risk factors (see Figure 1). (who.int)
  • Blood pressure circadian rhythms in weightlessness (BMI) Blood pressure Measurement Instrument (BMI) CARDIOCOG-2 Cardiovascular adaptation to weightlessness (RHYTHM) Effects of microgravity on the peripheral subcutaneous veno-arteriolar reflex in humans. (wikipedia.org)
  • Under these conditions, physiological adaptation becomes more and more complex. (occe.eu)
  • Studies have shown that cell-to-cell mitochondrial transfer plays an essential role in regulating cardiovascular system development and maintaining normal tissue homeostasis under physiological conditions. (frontiersin.org)
  • In fact, the last decade has been rich in illustrating the possible roles played by apelin in human physiology, namely as a regulating peptide of cardiovascular, hypothalamus-hypophysis, gastrointestinal, and immune systems. (nih.gov)
  • It will also address the physiology of the time period immediately after exercise as an important biological phenomenon that acupuncturists can use to the advantage of their clients. (valleyhealthclinic.com)
  • Prior to my appointment as PVC in February 2020 I have previously been Associate Dean for Scholarship, Research and Knowledge Transfer in the Faculty of Science, Head of the Research Institute for Sport and Exercise Sciences, interim Director of School of Sport and Exercise Sciences as well as Professor of Exercise and Cardiovascular Physiology. (ljmu.ac.uk)
  • This course provides an opportunity to learn key concepts in the areas of cell biology, genetics, ecology, and basic human physiology and to develop student capacity to effectively communicate their understanding. (aps1.net)
  • We also work on algorithms for simulations of various phenomena in physics and physiology. (lu.se)
  • Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2alpha gain-of-function mutation. (ox.ac.uk)
  • Preventing disease in the 21st century: early breast milk exposure and later cardiovascular health in premature infants. (ox.ac.uk)
  • In this review article, we discuss the role of breast milk in preventing early adulthood cardiovascular disease in infants born premature. (ox.ac.uk)
  • Furthermore, we aim to demonstrate the vital role of early breast milk exposure in preventing cardiovascular disease in preterm infants. (ox.ac.uk)
  • It is well-documented that abnormally high levels of IGF-1, seen in acromegaly, are associated with higher mortality and a higher prevalence of cancer and cardiovascular disease. (brinkzone.com)
  • If low IGF-1 levels are associated with an increased risk of developing cardiovascular disease and high IGF-1 levels are associated with an increased risk of developing cancer, there might be an optimal set point for the GH/IGF-1 axis associated with increased longevity. (brinkzone.com)
  • A notable study investigated the relationship between IGF-1 levels and all-cause/cause-specific mortality, cardiovascular disease and cancer, in a national representative sample of community-dwelling older persons over 65 years of age. (brinkzone.com)
  • This study found no significant associations were found between IGF-1 levels and nonfatal cardiovascular disease and fatal and nonfatal cancer. (brinkzone.com)
  • High exposure to environmental noise can play a role in cardiovascular disease . (wikipedia.org)
  • The focus of my research has been on hypertension and cardiovascular disease, where there have been documented associations between occupational stress and cardiovascular disease. (cdc.gov)
  • Furthermore, severe PE is a major cause of maternal morbidity (i.e., stroke and liver rupture) and negative long-term outcomes (i.e., cardiovascular disease and diabetes mellitus) as well as adverse perinatal effects, such as prematurity and intrauterine growth restriction [ 5 , 10 ]. (hindawi.com)
  • Hypertension (HTN) and smoking are established risk factors for cardiovascular disease ( U.S. Department of Health and Human Services 2000 ), the leading cause of death worldwide ( World Health Organization 2009 ). (nih.gov)
  • Breast-feeding influences on later life - cardiovascular disease / D.A. Leon, G. Ronalds -- 14. (who.int)
  • 1. The burden of cardiovascular disease is increasing rapidly in Africa, and it is now a public health problem throughout the African Region. (who.int)
  • Cardiovascular disease has a major socioeconomic impact on individuals, families and societies in terms of health-care costs, absenteeism and national productivity. (who.int)
  • it also allowed the development of complex physiological responses. (nobelprize.org)
  • There is evidence that besides the two cannabinoid receptor subtypes cloned so far additional cannabinoid receptor subtypes and vanilloid receptors are involved in the complex physiological functions of the cannabinoid system that include motor coordination, memory procession, control of appetite, pain modulation and neuroprotection. (nel.edu)
  • Astronauts experience changes in their cardiovascular, respiratory, and musculoskeletal systems during spaceflight, which can affect their capacity to exercise and to maintain blood pressure when standing after return to Earth. (nasa.gov)
  • Despite recent progress in our understanding of the physiological mechanisms regulating body weight and energy expenditure, obesity remains a major worldwide health crisis with an array of vascular, metabolic, and psychosocial consequences [ 1 , 2 ]. (hindawi.com)
  • Thermoregulation and metabolic heat exchange in humans. (irunfar.com)
  • Scientists are interested in placebo responses because the effects of belief on human experience and behavior provide an entry point for studying internal control of affective, sensory, and peripheral processes. (jneurosci.org)
  • The study of the placebo effect reflects a current neuroscientific thought that has as its central tenet the idea that "subjective" constructs such as expectation and value have identifiable physiological bases, and that these bases are powerful modulators of basic perceptual, motor, and internal homeostatic processes. (jneurosci.org)
  • Recovery" can also refer to a certain set of physiological processes or states which are distinct from resting physiological states and from the physiological state of exercise.This view of exercise recovery is usually localized: it assesses whether the muscles are ready to perform on the day of an event, or if they are weakened or injured. (valleyhealthclinic.com)
  • Results could provide a better understanding of the mechanisms of these adaptations on long-duration missions and support development of methods for assessing cardiovascular and respiratory effects on blood pressure before and after spaceflight. (nasa.gov)
  • With the ability to scan the brain using magnetic resonance imaging (MRI), researchers have been able to note the physiological changes that occur in the brains of those who pray regularly. (breakingchristiannews.com)
  • For almost one hundred years, the exact role of human brain structures controlling the cardiorespiratory response to exercise ('central command') has been sought. (ox.ac.uk)
  • In this article, we will summarise our current understanding of the physiological interactions between the gut and brain, termed the "gut-brain axis," focussing particularly on the interactions of gut hormones with the CNS and vagus nerve [ 6 ]. (hindawi.com)
  • Microglia cells play important roles not only in the survey of the brain parenchyma for danger-associated patterns and the neuroimmune system's response to these patterns, but also in physiological conditions related to cognition such as shaping neural circuit activity [ 12 ]. (springer.com)
  • What is the science behind the neurological and biological phenomena you describe in this interaction between humans and animals? (nausa.co)
  • There is some irony that nature where generations of humans experienced "fight or flight" is now our respite from stress. (naturecanada.ca)
  • The adverse effects of noise exposure (i.e. noise pollution ) could include: interference with speech or other 'desired' sounds, annoyance, sleep disturbance, anxiety, hearing damage and stress-related cardiovascular health problems. (wikipedia.org)
  • His major areas of research are the cardiovascular effects of occupational stress and the social and organizational factors that play a role in indoor air quality problems. (cdc.gov)
  • Today, I am going to be talking about stress as a phenomenon that includes both physical and psychological outcomes. (cdc.gov)
  • Psychosocial factors, such as stress and threat, can cause both psychological and physiological outcomes. (cdc.gov)
  • For example, just being with a dog for five to 10 minutes can decrease blood pressure and stress hormones, and provide a long-term boost to cardiovascular health. (nausa.co)
  • The human body is intelligently balanced with a complex, built-in network for adapting to stress. (valleyhealthclinic.com)
  • Stress is a powerful physiological and psychological state. (livescience.com)
  • Its other very distinct mechanisms that relates to stress therapy, Cellulite treatment, cardiovascular disorders and toning of the skin and reducing scar marks are discussed in the following segment. (o3medoz.co.za)
  • Stress coping models or process models have shown that the strain associated with caregiving can result in psychological distress and interference with the immune system (8) and cardiovascular functions (6,7). (cdc.gov)
  • Hence, even though physiological and pathophysiological phenomena are well described in dogs and cats, the underlying mechanisms are often not known and studies investigating causality specifically are scarce. (uzh.ch)
  • The placebo effect is a psychobiological phenomenon that can be attributable to different mechanisms, including expectation of clinical improvement and pavlovian conditioning. (jneurosci.org)
  • So far, most of the neurobiological mechanisms underlying this complex phenomenon have been studied in the field of pain and analgesia, although recent investigations have successfully been performed in the immune system, motor disorders, and depression. (jneurosci.org)
  • DATA EXTRACTION: Outcomes were measures of physical activity (self-reported and objectively measured) and cardiovascular fitness. (ox.ac.uk)
  • We also discussed the advantage and challenges of mitochondrial transfer strategies, including cell-based mitochondrial transplantation, extracellular vesicle-based mitochondrial transplantation, and naked mitochondrial transplantation, for the treatment of cardiovascular disorders. (frontiersin.org)
  • Further studies are necessary to add new elements in the literature to improve new therapies to treat cardiovascular disorders. (bvsalud.org)
  • Animal experiments and functional imaging studies have provided clues, but the underlying electrophysiological activity of proposed relevant neural sites in humans has never been measured. (ox.ac.uk)
  • We provide direct electrophysiological evidence highlighting the PAG as an important subcortical area in the neural circuitry of the cardiorespiratory response to exercise, since stimulation of this structure is known to alter blood pressure in awake humans. (ox.ac.uk)
  • The experiment tests two hypotheses that are based on a more than two decades long research in understanding the reaction of the cardiovascular system to exposure to microgravity. (wikipedia.org)
  • Recent evidence suggests that early exposure to breast milk slows down or even arrests those pathophysiological changes, thereby mitigating the long-term adverse effects of premature birth on cardiovascular health. (ox.ac.uk)
  • The effects in humans of exposure to environmental noise may vary from emotional to physiological and psychological. (wikipedia.org)
  • Another reason is exposure to behavioural and physiological risk factors (Figure 1) which are responsible for 75% of CVDs.1 These risk factors have been prioritized according to their impact on mortality and morbidity, possibility of modification through primary prevention, and quantification by available easy standardized methods. (who.int)
  • 2023. Housing conditions affect adult zebrafish (Danio rerio) behavior but not their physiological status. (awionline.org)
  • It has also been used to evaluate the impact of manipulative therapeutics and body position on autonomic regulation of the cardiovascular system. (biomedcentral.com)
  • It should be remembered that these pollutants (ozone, VOCs, particles, SO2, NO2) attack and contribute to the deterioration of the human respiratory system. (occe.eu)
  • The phenomenon of intercellular mitochondrial transfer has been discovered in the cardiovascular system. (frontiersin.org)
  • In this review, we summarized the mechanism of mitochondrial transfer in the cardiovascular system and outlined the fate and functional role of donor mitochondria. (frontiersin.org)
  • Nowadays, more and more studies have revealed that cells in the cardiovascular system (such as cardiomyocytes, vascular smooth muscle cells, endothelial cells, et al. (frontiersin.org)
  • The literature has already demonstrated that auditory stimulation with music influences the cardiovascular system. (bvsalud.org)
  • The use of back belts may produce temporary strain on the cardiovascular system. (cdc.gov)
  • The consequences are then numerous such as the increase of respiratory affections, the deterioration of the ventilatory function, the resurgence of the cardiovascular morbidity or even, the damage of the defenses of the organism. (occe.eu)
  • A major goal of this compendium is to inform the reader of procedures for assessing irrita tion in humans and to provide information of value in the continued interpretation and development of empirical databases upon which future reasoned regulatory health decisions can be made. (cdc.gov)
  • Cardiovascular health of premature infants reaching early adulthood is an area of ongoing research. (ox.ac.uk)
  • humor , "body fluid"), controlled human health and emotion. (wikipedia.org)
  • She found there were more stories like hers that explain how the health and happiness of humans an animals are interlaced. (nausa.co)
  • For example, Järup and Akesson (2009) recently reviewed the literature on cadmium and health effects and identified single-study-reported associations between cadmium and cardiovascular effects other than HTN. (nih.gov)
  • Microorganisms play a crucial role in the field of biology, particularly when it comes to understanding their impact on human health. (filosofia-internet.net)
  • More research is needed to determine the long-term effects of silence on cardiovascular health, but these results are promising. (healthline.com)
  • In fact, it can alter our metabolism, increase our susceptibility to infections, worsen our cardiovascular health and, unsurprisingly, take a huge toll on our mental wellbeing. (livescience.com)
  • The World Health Organization (WHO) published a report on the "Ten Threats to Global Health in 2019", which highlighted the main threats to human health across the globe. (news-medical.net)
  • The effects of climate change on human health are often invisible in the short term. (occe.eu)
  • However, they can have serious consequences for human health over the long term, hence the importance of observing their correlation. (occe.eu)
  • Increasing temperature increases the frequency of phenomena such as heatwaves and droughts that have direct effects on human health. (occe.eu)
  • Exploring the Biological Contributions to Human Health: Does Sex Matter? (nationalacademies.org)
  • My background is as a cardiovascular physiologist interested in the health and well being of different human populations from elite athletes to clinical groups. (ljmu.ac.uk)
  • Therefore, it is paramount to understand the principles of biological activity, bioavailability and metabolism of grape flavonoids in relation to human health. (oatext.com)
  • Aging is a physiological process that involves all living things and is connected to the loss of skills, the way of life in the past, genetics, and emotional and psychological changes. (bvsalud.org)
  • Human Molecular Genetics, vol. (private-art.com)
  • Human Molecular Genetics, Several candidates of the National Academy of Sciences of the United States of America, vol. (private-art.com)
  • Measuring trace immune factors in human milk: workshop summary / S. Filteau -- 25. (who.int)
  • Identification of neurocircuitry controlling cardiovascular function in humans using functional neurosurgery: implications for exercise control. (ox.ac.uk)
  • The neurocircuitry underlying human cardiovascular control during exercise has yet to be fully elucidated. (ox.ac.uk)
  • Identifying cardiorespiratory neurocircuitry involved in central command during exercise in humans. (ox.ac.uk)
  • Assessment of upper respiratory tract and ocular irrita tive effects of volatile chemicals in humans. (cdc.gov)
  • Time in nature can directly counteract some of the physiological and psychological effects of anxiety. (naturecanada.ca)
  • These are physiological effects from psychosocial factors. (cdc.gov)
  • Cardiobreath studies the combined effects of cardiovascular and respiratory adaptations on blood pressure regulation during spaceflight. (nasa.gov)
  • the existence of placebo effects suggests that we must broaden our conception of the limits of endogenous human capability. (jneurosci.org)
  • While this doesn't necessarily mean humans will experience the same effects, it's an intriguing invitation for further research. (healthline.com)
  • Obese dogs and cats show many features of human obesity. (uzh.ch)
  • Humans also experience this biological phenomenon when we are stressed. (naturecanada.ca)
  • Aging is a biological and psychological phenomenon that affects the family and social level. (bvsalud.org)
  • Increasing student capacity to critically analyze and relate phenomena of the physical world in terms of the fundamental laws of physics is the underlying objective of this course. (aps1.net)
  • These three phenomena indicate that receptors are highly dynamic molecules and sample several active and inactive states stochastically (for review, see refs. (nature.com)
  • Body position significantly influences cardiac autonomic drive in humans. (biomedcentral.com)
  • Background: The aim of the study was to investigate the effect of a simulated heat-wave on the labour productivity and physiological strain experienced by workers. (mdpi.com)
  • These differences should be considered when autonomic regulation of cardiovascular function is studied in different postures. (biomedcentral.com)
  • From military activity to mountaineering, physiological feats up high have inspired generations of scientists. (irunfar.com)
  • HRF-1 provides an on-orbit laboratory that enables scientists conducting human life science research to evaluate the physiological, behavioral, and chemical changes induced by space flight. (nasa.gov)
  • Research performed using HRF-1 provides data to help scientists understand how the human body adapts to long-duration spaceflight. (nasa.gov)
  • Scientists point out that animals (and potentially humans as well) can develop so-called 'ghrelin resistance', depending on the type of stressors. (livescience.com)
  • Left ventricular wall segment motion after ultra-endurance exercise in humans assessed by myocardial speckle tracking. (ljmu.ac.uk)
  • Engineered Heart Tissues-2 continues work with 3D cultured cardiac muscle tissue to assess human cardiac function in microgravity. (nasa.gov)
  • Moreover, microgravity conditions are essential to study rearrangement phenomena, such as coarsening and coalescence, disentangled from drainage. (nasa.gov)
  • Instead, methods are needed which non-invasively can localize, quantify and characterize fat in the human body. (lu.se)
  • We believe that MRI can provide the solution and we work on the development and improvement of methods for measuring the amount and chemical composition of fat in various parts of the human body. (lu.se)
  • This has more a research of the volume of these phenomena than easy e-versions of future has. (private-art.com)
  • Cardiovascular Research, vol. (private-art.com)
  • International Society for Research in Human Milk and Lactation. (who.int)
  • Proceedings of the 12th Symposium of the International Society for Research in Human Milk and Lactation 2004 held at Queens College, Cambridge. (who.int)
  • Within this context, environmental noise is generally present in some form in all areas of human, animal, or environmental activity. (wikipedia.org)
  • This project-based course offers students an opportunity to investigate and explore the fundamental principles of environmental science and the numerous related issues caused by human activity. (aps1.net)
  • It is a process in which there is gradual and unavoidable loss of organ function, generating changes in various human systems. (bvsalud.org)
  • Carbonic Acid is naturally present in the human body and without it our bodies will not be able to function in a normal way. (o3medoz.co.za)
  • Evolution of human lactation and complementary feeding: Implications for understanding contemporary cross-cultural variation / D.W. Sellen -- 19. (who.int)
  • This may clinically manifest by an increased risk of cardiovascular incidents, hypertension, and reduced exercise tolerance. (ox.ac.uk)
  • Actually there have been dozens and dozens of human disasters and hazardous waste sites that have been studied. (cdc.gov)
  • Our studies have shown that changes occur in this region during anticipation of exercise, indicating a possible role in the central command of cardiovascular variables before and during exercise. (ox.ac.uk)
  • This physiological response enables the "fight"- the buffalo charges the wolf, the blue jay attacks the owl, the mother bear protects her cubs. (naturecanada.ca)
  • permanent dead link] "ESA Human Spaceflight Science Newsletter" (PDF). (wikipedia.org)
  • A more than 2-fold increased risk of cardiovascular mortality was found for both low-normal (239% increased risk) and high-normal (203 % increased risk) IGF-1 levels. (brinkzone.com)
  • It is interesting that having low-normal IGF-1 levels impose a greater risk of all-cause mortality and cardiovascular mortality than having high-normal IGF-1 levels. (brinkzone.com)
  • feline and human diabetes are similar in respect to their pathophysiology, underlying risk factors and treatment strategies. (uzh.ch)