• Jennes W, Sawadogo S, Koblavi-Deme S, Vuylsteke B, Maurice C, Cellular Human immunodeficiency virus (HIV)- protective factors: a comparison of HIV- exposed seronegative female sex wprkers and female blood donors in Abidjan, Cote d' lvoire. (ijmedicine.com)
  • Human immunodeficiency virus (HIV-1) can cause infection in the central nervous system (CNS) of an infected individual and is responsible for HIV-associated neurocognitive disorder (HAND). (biomedcentral.com)
  • TBE virus infection is a risk for certain travelers and for laboratory workers who work with the virus. (cdc.gov)
  • This report summarizes the epidemiology of and risks for infection with TBE virus, provides information on the immunogenicity and safety of TBE vaccine, and summarizes the recommendations of the Advisory Committee on Immunization Practices (ACIP) for use of TBE vaccine among U.S. travelers and laboratory workers. (cdc.gov)
  • The most recognized clinical manifestation of TBE virus infection is acute neurologic disease, which usually results in hospitalization, often permanent neurologic or cognitive sequelae, and sometimes death. (cdc.gov)
  • A major finding from human NV volunteer studies is that persons with strains containing 2 mutated alleles of the α(1,2) fucosyltransferase ( FUT2 ) gene were resistant to NV infection ( 16 - 20 ). (cdc.gov)
  • The disease can also be spread from animals to humans, with ruminants and dogs providing the principal source of infection for humans. (wikipedia.org)
  • Blockade of Attachment and Fusion Receptors Inhibits HIV-1 Infection of Human Cervical Tissue. (ijmedicine.com)
  • Hladik F. Initial Events in Establishing Vaginal Entry and Infection by Human Immunodefiicnecy Virus Type-1. (ijmedicine.com)
  • Kalter DC, Gendelman HE, Meltzer MS. Infection of human epidermal Langerhans's cells by HIV. (ijmedicine.com)
  • On the other hand, most isolates from dogs and cats have been from genotypes C and D, and therefore, do not pose a significant risk for human infection. (antimicrobe.org)
  • The immune system could play a crucial role in virus infection. (medsci.org)
  • The successful development and implementation to intervene prevention and treatment of virus infection over the past hundred years have had great advances on human and animal health. (medsci.org)
  • However, to this day, in the fight against virus infection, there is no real winner. (medsci.org)
  • The critical role of the immune system has been found in the discovery that there are reported high morbidity and mortality rates of human CoV infection in immunocompromised host as well as patients with comorbidities [ 3 - 6 ]. (medsci.org)
  • They are also key players in spread of infection via trans-CD4 T cell infection (or in cis), and stimulation of adaptive immune responses in attempt to eliminate virus. (jscimedcentral.com)
  • Infection in humans is almost exclusively due to zoonosis, either through direct contact with infected animals or from contaminated dairy products [ 4 ]. (biomedcentral.com)
  • Although human listeriosis occurs anytime during pregnancy, it is frequently detected during the third trimester, resulting in intrauterine fetal death, abortion, preterm birth, or neonatal infection with a severe septic syndrome known as granulomatosis infantiseptica. (biomedcentral.com)
  • Human CMV infection is controlled by T cell-mediated immunity and in immunosuppressed transplant patients it is associated with acute allograft rejection as well as chronic allograft vasculopathy. (aai.org)
  • Although the engineers instantly not listed, Lennox imposed a not human film from Stewart in 1990. (impeckoble.com)
  • Human-to-human transmission of NoV occurs primarily through the fecal-oral route, with the small intestine being the initial site of viral replication ( 1 , 4 ). (cdc.gov)
  • Bronchial epithelial cells (BEAS-2B cells and primary bronchial epithelial cells) were exposed to heat-inactivated Haemophilus influenzae , Pseudomonas aeruginosa or Streptococcus pneumoniae and subsequently infected with respiratory syncytial virus (RSV), type 2 human adenovirus or influenza B. Levels of pro-inflammatory cytokines, viral replication and expression of pattern recognition receptors were determined in culture supernatants and/or cell lysates. (biomedcentral.com)
  • We collaborate with Drs. Greiner, Brehm and Luban here at UMMS and Dr. Leonard Schultz at Jackson Laboratories on humanized mouse models for the generation of human monoclonal antibodies and as models for passive immunotherapy for bacterial or viral infections. (umassmed.edu)
  • The laboratory has also been involved in pharmacokinetic and pharmacodynamic studies of IgG and IgA human monoclonal antibodies, in several bacterial and viral infections. (umassmed.edu)
  • Sections on the prevention of bacterial pneumonia in mechanically ventilated and/or critically ill patients, care of respiratory-therapy devices, prevention of cross-contamination, and prevention of viral lower respiratory tract infections (e.g., respiratory syncytial virus {RSV} and influenza infections) have been expanded and updated. (cdc.gov)
  • As with other herpes viruses, CMV has struck a balance with the human immune system, allowing enough viral replication for CMV to persist and to spread easily from person to person while avoiding serious illness or injury caused by uncontrolled replication ( 1 ). (aai.org)
  • Recently, we developed the first tractable genetic system for Parvimonas micra, which is a ubiquitous Gram-positive pathobiont of the human microbiome involved in numerous types of inflammatory infections as well as a variety of malignant tumors. (bvsalud.org)
  • A plethora of new evidence suggests that these microbes play outsized roles in establishing synergistic polymicrobial infections at many different sites in the human body. (bvsalud.org)
  • Infections with respiratory viruses are known triggers of exacerbations of these diseases. (biomedcentral.com)
  • Streptococcus pyogenes is a major human-specific bacterial pathogen that causes a wide array of manifestations ranging from mild localized infections to life-threatening invasive infections. (nih.gov)
  • In contrast, there is reasonably good epidemiologic evidence to suggest that beavers can be a source for human infections ( 53 , 136 , 155 ). (antimicrobe.org)
  • The attempts to treat virus infections occur even earlier than there was an understanding of the concept of a virus as an independent entity. (medsci.org)
  • Les anticorps du jaune d'œuf de poule (IgY), production et utilisation en immunisation passive contre les infections entériques bactériennes : une revue. (ac.be)
  • Unfortunately poultry meat is one of the major sources of food borne bacterial infections in humans such as Salmonellosis (Mayrhofer et al. (ac.be)
  • As a facultative intracellular food-borne pathogen, it is responsible for both severe central nervous system and fetal infections in humans and in a large variety of animals [ 5 ]. (biomedcentral.com)
  • Mycoplasmas are common inhabitants of the human respiratory and genitourinary tracts where they produce chronic infections, they also are able to invade other tissues and in some cases induce an autoimmune response [ 5 ]. (biomedcentral.com)
  • Felix d'Herelle first coined the term "bacteriophage" ( 4 ), literally meaning "bacterium eater," and began using phages to treat bacterial infections in human patients ( Fig. 1 ). (asm.org)
  • Activated form of natural antimicrobial improves safety of beef and poultry by preventing attachment and growth of bacteria. (ift.org)
  • The interaction of LF with microbial surfaces-OMPs of Gram-negative bacteria in particular-has led to other antimicrobial mechanisms, such as the inhibition of microbial attachment to sub-epithelial matrix proteins and detachment of bacteria from mucosal surfaces. (ift.org)
  • Etiologic factors such as bacteria, fungi, and viruses as well as various contributing factors such as trauma, root resorptions, perforations, and dental malformations play an important role in the development and progression of such lesions. (docshare.tips)
  • Lactobacillus acidophilus (L. acidophilus) is a type of probiotic ("good" bacteria) found in the human gut, mouth, and vagina, and also in certain foods. (medlineplus.gov)
  • This chronic inflammatory disease results from the response to bacteria in dental biofilm and may remain confined to the gingival tissues with minimal tissue alterations or this disease may progress to extreme periodontal destruction with the loss of attachment and alveolar bone. (bvsalud.org)
  • The therapeutic use of bacteriophages, viruses that infect and kill bacteria, is well suited to be part of the multidimensional strategies to combat antibiotic resistance. (asm.org)
  • The diplomonads include free-living and parasitic organisms, but Giardia is the only one recognized as a human pathogen. (antimicrobe.org)
  • However, viruses including alphaherpesvirinae have developed strategies to interfere with the function or maturation of DCs, causing immune dysfunction and avoidance of pathogen elimination. (biomedcentral.com)
  • Pseudomonas aeruginosa is well known as an opportunistic human pathogen characterized by a high intrinsic antibiotic tolerance [ 1 , 2 ]. (biomedcentral.com)
  • Trade names are Encepur N and FSME-Immun CC. There is no specific antiviral treatment for TBE. (wikipedia.org)
  • Conversely, interlekin-8 (IL-8) is a known proinflammatory chemokine and is known to be over-expressed in human brain microvascular endothelial cells in response to gp120. (biomedcentral.com)
  • Furthermore, IL-8 has also been reported to be involved in a STAT1-dependent mechanism for gp120-mediated increased IL-8 production in human brain microvascular endothelial cells [ 21 ]. (biomedcentral.com)
  • Human vascular endothelial cells (EC) 3 display both class I and class II MHC molecules and are directly recognized by CD8 + and CD4 + alloreactive T cells, respectively ( 12 , 13 , 14 , 15 ). (aai.org)
  • Kirkham (13), studying 1000 human teeth with extensive periodontal disease, found only 2% of lateral canals associated with the involved periodontal pocket. (docshare.tips)
  • In the arena of periodontal medicines, the studies of past decades suggest a link between human periodontal afflictions and certain systemic disorders such as cardiovascular diseases, diabetes mellitus, respiratory disorders, preterm birth, autoimmune disorders, and cancer. (encyclopedia.pub)
  • Furthermore, the concept of periodontal medicine as a new discipline concentrating on validating this association and its biological mechanism through animal and humans has also been studied [ 5 ] . (encyclopedia.pub)
  • and influenza virus are often caused by inhalation of contaminated aerosols. (cdc.gov)
  • Fanibunda S, Velhal E. CD4 independent binding of HIV gp120 to Mannose Receptor on Human Spermatozoa. (ijmedicine.com)
  • Furthermore gp120 has also been shown to increase IL-6 production in mixed human brain cell culture [ 15 ]. (biomedcentral.com)
  • In this study, we sought to address the question as to whether gp120 would affect IL-8 expression in a human astrocytic cell line, SVGA. (biomedcentral.com)
  • An in vitro model for NoV replication remains elusive, making study of the virus difficult. (cdc.gov)
  • Rubella Virus Replication and Links to TeratogenicityJIA-YEE LEE* ANDD. (vdocuments.net)
  • To prevent infected cell lysis, recombinant replication deficiency virus has been developed as a gene delivery tool to replace wild-type adenovirus (recombinant AdV in "application" part). (genemedi.com)
  • Brucellosis is a widespread and economically important infectious disease of humans and animals caused by members of the genus Brucella . (biomedcentral.com)
  • TBE virus can cause acute neurologic disease, which usually results in hospitalization, often permanent neurologic or cognitive sequelae, and sometimes death. (cdc.gov)
  • In the past dozen years, the outbreak of the novel coronavirus is the third on record spillover of an animal coronavirus to humans after occurring of severe acute respiratory syndrome (SARS) started in 2002 and Middle East respiratory syndrome coronavirus (MERS-CoV) in 2014, which is resulting in a pandemic in global. (medsci.org)
  • Salmonella can cause a spectrum of pathological conditions such as acute gastroenteritis and bacteraemia in humans by the mechanisms of colonization, invasion and penetration of the intestinal epithelium (Roberts et al. (ac.be)
  • It is clear that human milk can affect the immune system of the breasfed infant. (unu.edu)
  • The former Soviet Union conducted research on tick-borne diseases, including the TBE viruses. (wikipedia.org)
  • Tick checks, while useful for preventing some other tick-borne diseases such as Lyme borreliosis, would not be expected to be effective in the prevention of tick-borne encephalitis as the virus is transmitted within minutes of attachment by the tick. (wikipedia.org)
  • Not only do we generate new human monoclonal antibodies for our studies, but also for a large number of laboratories throughout the world for research on infectious diseases, cancer and autoimmune disease. (umassmed.edu)
  • This research often requires the tissue-specific expression of transgenes to better mirror human diseases, to visualize pathways being studied or to modulate the expression of a disease-related gene. (nature.com)
  • 1996). In Europe, although Salmonellosis records a fall in the number of cases since 2005, it remains second in the list of human zoonotic diseases across the EU with 160,649 people infected in 2006 (35 cases per 100,000). (ac.be)
  • However, in most cases, it is not clear whether there has been transmission between humans and cats or dogs, and if so, whether it was from zoonotic or anthropozoonotic (from human to animal). (antimicrobe.org)
  • In vitro experiments using NV virus-like particles (VLPs) directly showed NV VLP attachment to HBGA, resulting in VLP internalization into the cell ( 19 ). (cdc.gov)
  • It is more than two decades the presence of HIV virus has created a pandemic in human community. (ijmedicine.com)
  • Three virus sub-types also exist: European or Western tick-borne encephalitis virus (transmitted by Ixodes ricinus) Siberian tick-borne encephalitis virus (transmitted by I. persulcatus) Far-Eastern tick-borne encephalitis virus, formerly known as Russian spring summer encephalitis virus (transmitted by I. persulcatus). (wikipedia.org)
  • The gene product is synthesized as a propeptide and is referred to as human cationic antimicrobial peptide-18 (hCAP-18/LL-37). (biomedcentral.com)
  • Such influences are related to the fact that human milk is rich in various immunologically active factors, in particular the stable antibodies. (unu.edu)
  • We favour the hypothesis that at least some of the enhancing effect could be due to the anti-idiotypic antibodies (anti-antibodies) in human milk. (unu.edu)
  • We have shown the presence of such anti-antibodies against poliovirus in human milk [4]. (unu.edu)
  • Human monoclonal antibodies are characterized to study the humoral immune response in these disorders. (umassmed.edu)
  • Enterotoxigenic Escherichia coli,, Bordetella pertussis, Klebsiella pneumonia), she is also inventor of two human monoclonal antibodies against Staphylococcus aureus and Pseudomonas aeruginosa. (umassmed.edu)
  • The expertise at MassBiologics, particularly in the areas of Discovery and Process Development, has allowed rapid production of SARS CoV-2 proteins (including several spike proteins and N protein) and human antibodies and nanobodies , contributing to the evaluation and development of therapeutics and diagnostics. (umassmed.edu)
  • Cardona-maya W, The Role of mannose Receptor on HIV-1 Entry into Human Spermatozoa. (ijmedicine.com)
  • TBE is caused by tick-borne encephalitis virus, a member of the genus Flavivirus in the family Flaviviridae. (wikipedia.org)
  • Lambl, in 1859, described the genus Giardia more extensively and the human variant has been named after him, although not without controversy, in that Giardia duodenalis and Giardia intestinalis are also used frequently. (antimicrobe.org)
  • In the human gastroduodenal junction where NV has been shown to bind HBGA type 1 (Lewis b [Le b ]), is found exclusively on epithelial surfaces, whereas HBGA type 2 is primarily found at the glandular level ( 19 , 24 - 26 ). (cdc.gov)
  • It is primarily given as a 3-dose series, with the first dose given ideally within 24 hours of birth to prevent perinatal or early postnatal transmission of the virus. (medscape.com)
  • Lymphoid lineage DCs primarily differentiate into plasmacytoid DCs and occupy approximately 0.5% of peripheral blood mononuclear cells (PBMCs) in humans [ 2 ], but the cell population percentage is unclear in horses. (biomedcentral.com)
  • Human milk is a very complex fluid with a multitude of proteins, cells, and other components. (unu.edu)
  • Using the same 3-D model, but with highly purified Norwalk virus (NV), we attempted to replicate this study. (cdc.gov)
  • By going through up-to-date reports and, whenever possible, human clinical trials, we examine the versatility of phage therapy. (asm.org)
  • Tick-borne encephalitis (TBE) virus is a tickborne flavivirus that is focally endemic in a geographic region extending from western and northern Europe through to northern and eastern Asia ( 1 ). (cdc.gov)
  • The goal of the present study was to isolate and characterize equine lung-derived DCs (L-DCs) for use in studies of respiratory viruses and compare their features with equine blood-derived DCs (B-DCs), which are currently used for these types of studies. (biomedcentral.com)
  • TBE is posing a concerning health challenge to Europe, as the number of reported human cases of TBE in all endemic regions of Europe have increased by almost 400% within the last three decades. (wikipedia.org)
  • Upon attachment, interaction between the penton-base Arg-Gly-Asp (RGD) and cellular αv integrins, which can stimulate actin polymerization, leads to internalisation of the virus into the endosome. (genemedi.com)
  • This study was done to investigate the plasma and urine levels of human LL-37 in patients with UTI. (biomedcentral.com)
  • 111) infected African green monkey kidneycells with throat washings from patients with rubella and indi-rectly demonstrated the presence of RV by resistance to chal-lenge with an echovirus, while Weller and Neva (154) detectedcytopathic effects in human amnion cells infected with RVfrom blood and urine specimens. (vdocuments.net)
  • There have been strenuous efforts to reveal the mechanisms that the host defends itself against invasion by this virus. (medsci.org)
  • Tick-borne encephalitis (TBE) virus is focally endemic in parts of Europe and Asia. (cdc.gov)
  • The risk for exposure to infected ticks is highest for persons who are in areas where TBE is endemic during the main TBE virus transmission season of April-November and who are planning to engage in recreational activities in woodland habitats or who might be occupationally exposed. (cdc.gov)
  • All persons who travel to areas where TBE is endemic should be advised to take precautions to avoid tick bites and to avoid the consumption of unpasteurized dairy products because alimentary transmission of TBE virus can occur. (cdc.gov)
  • As a result, human outbreaks and volunteer studies have been the primary source for existing knowledge of NV epidemiology and pathogenesis, respectively ( 1 , 14 , 15 ). (cdc.gov)
  • shop introduction to basic milling basic information is an smoothing browser of application efficiency that does with the explanation and attachment of strong pharmacists infected on infected students of people. (impeckoble.com)
  • that viruses could be teratogenic agents was introduced.Greggs report initially drew little attention. (vdocuments.net)
  • Only two of these genotypes, A and B (Nash Groups 1/2 and 3 ( 150 , 151 ) are found in humans. (antimicrobe.org)
  • however, no small animal model for NoV mimics the disease manifestations observed in humans ( 7 , 11 - 13 ). (cdc.gov)
  • Their incidence and location have been well documented in both animal and human teeth (9-15). (docshare.tips)
  • The primary habitats of human and animal mycoplasmas are the mucous surface of the respiratory and urogenital tracts, the eyes, mammary glands and joints [ 5 ]. (biomedcentral.com)
  • Intracellular events, such as blocking of microbial attachment factors such as fimbriae (hairlike structures) and other adhesins (putative receptors), have been observed (Naidu and Bidlack, 1998). (ift.org)
  • The MMWR series of publications is published by the Epidemiology Program Office, Centers for Disease Control and Prevention (CDC), Public Health Service, U.S. Depart- ment of Health and Human Services, Atlanta, GA 30333. (cdc.gov)
  • Bacteriophages (phages) are viruses capable of infecting and replicating within bacterial cells. (asm.org)
  • Here we describe a model system, SELective Expression and Controlled Transduction In Vivo (SELECTIV), that enables efficient and specific expression of transgenes by coupling adeno-associated virus (AAV) vectors with Cre-inducible overexpression of the multi-serotype AAV receptor, AAVR. (nature.com)
  • Extracellular vesicle DNA from human melanoma tissues contains cancer-specific mutations. (gu.se)
  • Use of trade names and commercial sources is for identification only and does not imply endorsement by the Public Health Service or the U.S. Department of Health and Human Services. (cdc.gov)
  • Periodontitis, a major oral disease, affects a vast majority of the population but has been often ignored without realizing its long-fetched effects on overall human health. (encyclopedia.pub)
  • Additionally, the hexon component of AdV capsid can bind to coagulation factor X (FX) to activate TLR4 on the surface of splenic macrophages and thereby stimulate NF-κB dependent activation of IL-1β, which may help recruit polymorphonuclear leukocytes to the marginal zone of the spleen and clear virus from the spleen rapidly [49, 50]. (genemedi.com)