• Cai J, Donaldson A, Yang M, German MS, Enikolopov G, Iacovitti L. The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson's disease model. (jefferson.edu)
  • After transplantation of differentiated hESCs to a rodent model of PD, some grafts contained human midbrain-like DA neurons. (elsevierpure.com)
  • Sozzi E, Nilsson F, Kajtez J, Parmar M, Fiorenzano A. Generation of Human Ventral Midbrain Organoids Derived from Pluripotent Stem Cells . (lu.se)
  • Electrical stimulation of the midbrain increases heart rate and arterial blood pressure in awake humans. (ox.ac.uk)
  • Electrical stimulation of the midbrain in awake humans can cause a modest increase in cardiovascular variables that is not dependent on movement feedback from exercising muscles. (ox.ac.uk)
  • The 3 brain vesicles (prosencephalon or forebrain, mesencephalon or midbrain, and rhombencephalon or hindbrain) form around the end of the first gestational month. (medscape.com)
  • One of the most vital parts of the brain is the midbrain, also known as the mesencephalon. (nhnscr.org)
  • Truncus encephali (Hirnstamm) Gliederung Mesencephalon Pons Medulla oblongata Grundbauplan Basis lange absteigende (motorische) Bahnen - Mesencephalon: Basis pedunculi cerebri - Pons: Pars basilaris - Medulla oblongata: Pyramis Tegmentum aufsteigende Bahnen z.B. Lemniscus medialis (Haube) Kerngebiete - Formatio reticularis In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. (web.app)
  • part of the brain consisting of the medulla oblongata, the pons Varoli and the mesencephalon. (infovisual.info)
  • WNV-specific qRT-PCR detected WNV RNA in brain tissue (mesencephalon, cerebral cortex, and medulla oblongata) and in the spinal cord. (cdc.gov)
  • The tegmentum of the pedunculus cerebri may be regarded as the continuation upwards of the formatio reticularis of the medulla oblongata and the dorsal or tegmental portion of the pons into the mesencephalon. (co.ma)
  • The tegmenta of opposite sides are, to some extent, marked off from each other in the median plane by a prolongation upwards of the median raphe of the pons and medulla oblongata, although, in the inferior part of the mesencephalon, this is much obscured by the decussation of the brachia conjunctiva. (co.ma)
  • Some taxonomies describe the brain stem as the medulla and mesencephalon, whereas others include diencephalic regions. (wikidoc.org)
  • Hjärnstammen (truncus encephali på latin) består av medulla oblongata, pons och mesencephalon och är ett av kroppens absolut mest hjärnstammen (truncus encephali) som består av mitthjärnan. (web.app)
  • MEDULLA OBLONGATA Truncus encephali (Hirnstamm) Gliederung Mesencephalon Pons Medulla oblongata Grundbauplan Basis lange absteigende (motorische) Bahnen - Mesencephalon: Basis pedunculi cerebri - Pons: Pars basilaris - Medulla oblongata: Pyramis Tegmentum aufsteigende Bahnen z.B. Lemniscus medialis (Haube) Kerngebiete - Formatio reticularis The brain stem known as truncus encephalon has three parts, namely mesencephalon, pons, and medulla oblongata. (web.app)
  • This analysis confirmed clear regional differences between patients and controls: patients had increased nAChR density in the epithalamus, ventral mesencephalon and cerebellum, but decreased nAChR density in the right dorsolateral prefrontal region. (unige.ch)
  • Dr. Jenny Nelander Wahlestedt has a MSc in Biomedicine from Lund University and did her PhD education at Lund University with Prof. Malin Parmar, where she studied the human ventral mesencephalon with focus on mesencephalic dopaminergic neurons. (lu.se)
  • The olfactory lobes of brain of human beings are a pair of poorly developed, club shaped, widely separated bodies, which are visible from the ventral surface only. (topclassnotes.in)
  • Petersén Å, Hansson O, Emgård M and Brundin P.Cell Transplantation 9: 577-584 (2000)AbstractTransplantation of embryonic ventral mesencephalon is a potential therapy for patients with Parkinson's disease. (lu.se)
  • Dr. Wahlestedt defended her PhD thesis (Characterization of human dopaminergic neurons in the developing mesencephalon and upon differentiation of stem cells - for cell replacement therapy in Parkinson's disease) in 2013. (lu.se)
  • After her PhD studies she was employed at Skåne University Hospital in Lund, being responsible for tissue and cell preparation for the clinical trial TransEuro ( https://transeuro.org.uk/pages/partners.html ), in which patients with Parkinson´s disease was transplanted with dopaminergic neurons derived from human fetal tissue. (lu.se)
  • Australian Animal Health Laboratory, https://www.csiro.au/en/about/facilities-collections/acdp ) detected small amounts of virus antigen in association with inflammatory foci in the spinal cord only. (cdc.gov)
  • The brain and spinal cord are two essential components of the human nervous system. (nhnscr.org)
  • or spinal cord of humans or other animals by imaging the change in blood flow ( hemodynamic response ) related to energy use by brain cells. (theinfolist.com)
  • The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the MEDIODORSAL NUCLEUS OF THE THALAMUS. (edu.au)
  • We studied the effects on heart rate (HR) and mean arterial blood pressure (MAP) of electrically stimulating the thalamus and basal ganglia in awake humans undergoing neurosurgery for movement disorders (n = 13 Parkinson's disease, n = 1 myoclonic dystonia, n = 1 spasmodic torticollis). (ox.ac.uk)
  • The concept of subcortical dementia is reinforced by our data, which show disrupted functional connections between mesencephalon and cerebellar cortex, inferior and medial temporal regions, and pallidum. (nih.gov)
  • When nonhuman mammalian development is compared with human development, the study subjects must be compared at the same developmental stage (fetal, perinatal, postnatal) When collected appropriately, data from experimental studies of nonhuman mammalian embryos elucidate important aspects of human facial development. (medscape.com)
  • Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo. (rush.edu)
  • Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease? (rush.edu)
  • DBS is a widely used FDA-approved treatment and stem cell-derived dopamine neuron replacement has now evolved to the first in-human clinical trials. (lu.se)
  • The human red nucleus is not a uniform structure. (ajnr.org)
  • In fact, the latter forms the bulk of the human red nucleus and can be subdivided histologically by two medullary lamellae into three parts. (ajnr.org)
  • Because iron is deposited in the human red nucleus and gradient-echo sequences are more sensitive than spin-echo sequences in the detection of iron, a high-resolution gradient-echo MR sequence was used in this study to determine whether the medullary lamellae of the normal human red nucleus could be detected in vivo. (ajnr.org)
  • With the lamellae, the parvicellular subnucleus of the human red nucleus can be divided into its subdivisions. (ajnr.org)
  • High-resolution gradient-echo MR imaging is capable of depicting the medullary lamellae of the normal human red nucleus in vivo. (ajnr.org)
  • Histologically, the parvicellular subnucleus of the human red nucleus can be divided into three parts by medullary lamellae: the pars oralis, the pars dorsomedialis, and the pars caudalis (1) ( Figs 1 and 2 ). (ajnr.org)
  • Anatomic sections of the human brain have also shown the presence of lamellae in the red nucleus (2) . (ajnr.org)
  • In addition, previous studies, using histochemical methods, have shown inhomogeneous deposition of iron in high concentration in the human red nucleus (5) . (ajnr.org)
  • However, previous MR studies, using conventional spin-echo sequences, have shown the human red nucleus as a uniformly hypointense area on both T1- and T2-weighted images (6, 7) . (ajnr.org)
  • We analyzed the morphological features of dying cells in the developing axial structures of 5 human embryos between 5 and 8 weeks of postovulatory age. (karger.com)
  • According to our findings, apoptosis seems to be the most frequently observed type of PCD, but it is not the exclusive type of morphological cell death during the development of axial structures in human embryos. (karger.com)
  • However, the degree to which subcortical structures play a role in cardiovascular activation in awake humans has not been established. (ox.ac.uk)
  • RNA-seq reads were mapped to the human genome assembly hg38 using STAR aligner v4.1. (nih.gov)
  • ChIP-seq reads were mapped to the human genome assembly hg38 using Bowtie2 with --very-sensitive. (nih.gov)
  • The length of the human genome is about 3 billion base pairs. (lecturio.com)
  • Embryo 8943 was one of the embryos used by Bartelmez and Dekaban in their study of human brain development. (ehd.org)
  • The adult human brain has three sub-divisions. (topclassnotes.in)
  • The adult human brain weighs on average about 3 lb (1.5 kg) with a size (volume) of around 1130 cubic centimeters (cm3) in women and 1260 cm3 in men, although there is substantial individual variation. (studymode.com)
  • We also propose that the nAChR density increase in mesencephalon is involved in the pathophysiology of ADNFLE through the role of brainstem ascending cholinergic systems in arousal. (unige.ch)
  • The brainstem is an essential part of the human brain that controls vital functions like breathing and heart rate, among others. (nhnscr.org)
  • The tegmentum of the mesencephalon may be considered as presenting two parts: viz. (co.ma)
  • The sounds produced by humans by the passage of air through the LARYNX and over the VOCAL CORDS, and then modified by the resonance organs, the NASOPHARYNX, and the MOUTH. (lookformedical.com)
  • The human brain is one of the most complex and intricate organs in the human body. (nhnscr.org)
  • brain mapping Brain mapping is a set of neuroscience techniques predicated on the mapping of (biological) quantities or properties onto spatial representations of the (human or non-human) brain resulting in maps. (theinfolist.com)
  • The brain is the most complex organ in the human body, and it's responsible for regulating and controlling nearly every function in our body. (nhnscr.org)
  • The human brain is soft, whitish highly developed organ situated in the cranium or cranial cavity of the skull. (topclassnotes.in)
  • Human eyes are highly sensitive in discerning minimal differences in the structure of human faces and in distinguishing persons. (medscape.com)
  • Tissue samples were taken from the cervicothoracic region of normal human conceptuses. (karger.com)
  • Deep brain stimulation of the pedunculopontine region in the normal non-human primate. (ox.ac.uk)
  • This graph shows the total number of publications written about "Mesencephalon" by people in this website by year, and whether "Mesencephalon" was a major or minor topic of these publications. (rush.edu)