• symptoms
  • These results emphasize the importance of dealing effectively with patients at risk of dropping out of therapy.Patients who dropped out also reported improvement of depressive symptoms without therapy, but took much longer to improve than did patients who completed therapy. (scielo.br)
  • Furthermore, some research shows that improvements in symptoms and self-esteem are associated with dropping out of psychotherapy, 9 , 10 which may suggest that some patients terminate because they feel better. (scielo.br)
  • Methods and Results In the Department of Veterans Affairs cooperative study of amiodarone in congestive heart failure, 674 patients with New York Heart Association class II through IV symptoms and ejection fractions of ≤40% were treated with amiodarone or placebo for a median of 45 months in a randomized, double-blind, placebo-controlled protocol. (ahajournals.org)
  • Patients had, on average, struggled with symptoms for 17 years. (nytimes.com)
  • After three doses of MDMA administered under a psychiatrist's guidance, the patients reported a 56 percent decrease of severity of symptoms on average, one study found . (nytimes.com)
  • METHODS: The 'Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image: (UMPIRE)' trial is a multicenter, prospective, randomized, placebo controlled trial, designed to evaluate the effect of udenafil on myocardial ischemia and symptoms in female patients with MVA. (biomedsearch.com)
  • To meet criteria for a major depressive episode, a patient must have 5 of these 9 symptoms nearly every day for at least 2 weeks. (wikipedia.org)
  • CBT based on this model attempts to reverse patients' symptoms by altering their interpretation of their symptoms and/or the behaviours they engage in as a result. (wikipedia.org)
  • Under intense stress patients with BPD may exhibit transient dissociative or paranoid symptoms. (wikipedia.org)
  • clinicians
  • Equipping clinicians with a validated tool that allows for earlier identification of at-risk patients and an evidence-based method for motivating them will improve engagement. (onlineprnews.com)
  • Clinicians experience losses in the form of time spent on patient intakes, missed appointments prior to termination, and other diagnostic work performed. (wikipedia.org)
  • fail
  • Under conditions of high stress, borderline patients may fail to appreciate the "whole" of the situation and interpret events in catastrophic and intensely personal ways. (wikipedia.org)
  • medication
  • Around 30 to 40 per cent of patients who begin TB medication experience severe side effects, including hyperacidity, jaundice, loss of vision, vertigo and numbness in the limbs. (hindustantimes.com)
  • Patients, especially those from economically disadvantaged families, do not eat a balanced diet while on medication. (hindustantimes.com)
  • At the Ameritox lab in Greensboro, N.C., samples are used to determine if patients are taking the proper medication. (nytimes.com)
  • Both patient and health-care provider affect compliance, and a positive physician-patient relationship is the most important factor in improving compliance, The cost of prescription medication also plays a major role. (wikipedia.org)
  • Efforts to improve compliance have been aimed at simplifying medication packaging, providing effective medication reminders, improving patient education, and limiting the number of medications prescribed simultaneously. (wikipedia.org)
  • not in citation given] perhaps because people do not feel immediately threatened or, in the case of symptomless conditions such as raised cholesterol levels (hypercholesterolaemia) and raised blood pressure (systemic hypertension), feel no obvious benefits at the time of taking the medicines As patients are asymptomatic, they may not see a need to take medication. (wikipedia.org)
  • Basic demographics data like address and phone number are also recorded into the system along with the schedule of the patient for coming into Operation ASHA's centers to take their medication. (wikipedia.org)
  • When the patients come to the center to take their medication, their fingerprint is scanned along with the fingerprint of the health worker present. (wikipedia.org)
  • She then goes to the patients house to give her the medication and scan her fingerprint alongside. (wikipedia.org)
  • For example, when a patient anticipates a side effect of a medication, he/she can suffer that effect even if the "medication" is actually an inert substance. (wikipedia.org)
  • Only 10 to 40 percent of depressed elderly patients are given medication. (wikipedia.org)
  • rates
  • Response rates were lower in pelvic radiation and diabetic patients. (wiley.com)
  • Phase IIb data presented at the 20th Conference on Retroviruses and Opportunistic Infections (CROI) in March 2013 showed similar viral suppression rates of 76% for patients taking 100 mg cenicriviroc, 73% with 200 mg cenicriviroc, and 71% with efavirenz. (wikipedia.org)
  • Non-response rates were higher with cenicriviroc, however, largely due to greater drop-out of patients. (wikipedia.org)
  • Suicide rates are nearly twice as high in depressed patients as in the general population. (wikipedia.org)
  • clinical trials
  • If udenafil demonstrates cardioprotective effects, it may provide a novel therapeutic option to reduce myocardial ischemia and improve cardiac function in female MVA patients.Trial registration: Clinical Trials.gov: NCT01769482 (registered on 20 November 2012). (biomedsearch.com)
  • describe
  • Pharmacometrics can be defined as that branch of science concerned with mathematical models of biology, pharmacology, disease, and physiology used to describe and quantify interactions between xenobiotics and patients (human and non-human), including beneficial effects and adverse effects. (wikipedia.org)
  • To receive the corresponding point, an article should describe the number of withdrawals and dropouts, in each of the study groups, and the underlying reasons. (wikipedia.org)
  • baseline
  • 112 patients with OAG (21 with DM, 91 without DM) were assessed for retinal capillary blood flow as measured by Heidelberg retinal flowmetry (HRF) at baseline. (arvojournals.org)
  • therapist
  • Moreover, it has not been evaluated if a low-intensity version of ICBT without therapist contact could be an alternative for patients who do not need or are able to manage the full ICBT-program. (diva-portal.org)
  • Patients receive cues on therapist expertise through their interactions, and may feel the therapist is inadequate. (wikipedia.org)
  • therapy
  • The virologic and immunologic effects of cyclosporine as an adjunct to antiretroviral therapy in patients treated during acute and early HIV-1 infection. (actgnetwork.org)
  • In addition, patients receiving radiation therapy were then allowed to use smoked marijuana. (druglibrary.org)
  • Cognitive behaviour therapy (CBT) can reduce tinnitus distress but is not available for most patients. (diva-portal.org)
  • Background Although trials of amiodarone therapy in patients with congestive heart failure have produced discordant results with regard to effects on survival, most studies have reported a significant rise in left ventricular ejection fraction during long-term therapy. (ahajournals.org)
  • Conclusions Although amiodarone therapy resulted in a substantial increase in left ventricular ejection fraction in patients with congestive heart failure, this was not associated with clinical benefit in the population as a whole. (ahajournals.org)
  • Patient dropout is associated with numerous problems, such as: loss of potential patient improvement, poorer outcomes, increased likelihood of over-utilizing resources, and disruption in group therapy settings. (wikipedia.org)
  • eligible
  • Patients were considered eligible if they were aged between 15-70 yr, ASA physical status I-III, and were scheduled for lower limb surgery under spinal anesthesia. (clinicaltrials.gov)
  • Any adult patient with active systemic cancer diagnosed with acute ischemic stroke at the main MSKCC campus or at any of MSKCC's New York City outpatient center WCMC, NYPH/CUMC within the prior four weeks would be eligible. (clinicaltrials.gov)
  • often
  • There is no current research as to how often this occurs in patient dropout cases. (wikipedia.org)
  • It is often beneficial to both the client and the patient to have a balance in which the clinician asks questions and the patient also volunteers certain information. (wikipedia.org)
  • The Patient Protection and Affordable Care Act, often shortened to the Affordable Care Act (ACA) or nicknamed Obamacare, is a United States federal statute enacted by the 111th United States Congress and signed into law by President Barack Obama on March 23, 2010. (wikipedia.org)
  • Concurrent medical problems and lower functional expectations of elderly patients often obscure the degree of impairment. (wikipedia.org)
  • Patients with BPD are often characterized by intense affects, stormy relationships, and impulsive behaviors. (wikipedia.org)
  • Patients with BPD often experience intolerable feelings of emptiness that they attempt to fill with impulsive and self-damaging behaviors, such as substance abuse, risky sexual behavior, uncontrolled spending, or binge eating. (wikipedia.org)
  • effects
  • In addition, the study aims to compare the effects, good and/or bad, of enoxaparin with those of aspirin on patients with cancer and recent stroke. (clinicaltrials.gov)
  • Cyclically, long waiting lists have shown some increased dropout effects, further exacerbating the problem. (wikipedia.org)
  • When trials throw up results that companies don't like, they are perfectly entitled to hide them from doctors and patients, so we only ever see a distorted picture of any drug's true effects. (wikipedia.org)
  • It has been shown that, due to the nocebo effect, warning patients about side effects of drugs can contribute to the causation of such effects, whether the drug is real or not. (wikipedia.org)
  • make
  • Studies have found that almost all patients make a decision about whether to return or not after the intake interview. (wikipedia.org)
  • chronic
  • citation needed] This may affect patient health, and affect the wider society when it causes complications from chronic diseases, formation of resistant infections, or untreated psychiatric illness. (wikipedia.org)
  • Intervention
  • Protocol violations" may occur, such as when the patients do not receive the full intervention or the correct intervention or a few ineligible patients are randomly allocated in error. (wikipedia.org)
  • dose
  • Patients will be receive 6 months of subcutaneous enoxaparin (1 mg/kg BID with a maximum starting dose of 100 mg BID. (clinicaltrials.gov)
  • Patients will receive 6 months of oral aspirin (81 mg per day unless a higher dose is preferred by study physicians although the maximum acceptable dose will be 325 mg per day). (clinicaltrials.gov)
  • negatively
  • For example, a recently published study of 800 pain patients treated at a Veterans Affairs facility in North Carolina found that one-quarter of them tested negatively in a urine-screen test for a drug they had been prescribed, while 20 percent of patients tested positively for an illicit drug or a narcotic painkiller that was not prescribed. (nytimes.com)
  • enrollment
  • As each protocol was changed data forms were also revised in an effort to increase enrollment by reducing any burden of paperwork for investigators and patients. (druglibrary.org)
  • Clinical Trial Portals can include patient recruitment management applications that track actual vs projected enrollment, site recruitment plans, IRB/EC submission/approval dates, recruitment material management, outreach tactics and ROI. (wikipedia.org)
  • better
  • 12 When dropouts were included in the analysis, CBT outcomes were significantly better, which led to the question of whether there was significant variance in the performance of the dropout sample. (scielo.br)
  • Urine tests are by no means the first technique that doctors have used to try to better monitor how patients are using prescription narcotics. (nytimes.com)
  • For example, it may be used help the patient cope with their disability by better management of rest and activity within the boundaries of the energy constraints of the disorder, and does not actively attempt to improve the patient's physical or psychological capacity. (wikipedia.org)
  • time
  • As most of the trials suffer by time delays by both patient recruitment issues and patient drop-outs, Trial Portals having the ability to interact with Patients can enhance the patient motivation to stay in a trial. (wikipedia.org)
  • After a defined time period, the patients in the test group are assessed for health improvements in comparison with the control group. (wikipedia.org)
  • studies
  • In contrast to these favorable results with amiodarone, in the recently completed randomized, double-blind, placebo-controlled trial of amiodarone in patients with CHF conducted by the Department of Veterans Affairs Cooperative Studies Program, no improvement was observed in all-cause or sudden death mortality. (ahajournals.org)
  • The Multidisciplinary Association for Psychedelic Studies , a small nonprofit created in 1985 to advocate the legal medical use of MDMA, LSD, marijuana and other banned drugs, sponsored six Phase 2 studies treating a total of 130 PTSD patients with the stimulant. (nytimes.com)
  • In smoking cessation studies, for example, it is routine to consider all dropouts as failures. (wikipedia.org)
  • Questionnaires
  • The agreements, however, proved to be of limited value, so pain specialists turned to diagnostic questionnaires that were supposedly able to predict whether a patient was likely to abuse a narcotic because of factors like a family history of substance abuse. (nytimes.com)
  • data
  • This data suggests that OAG patients with DM may have more retinal capillary dropout associated with their disease compared to OAG patients without DM. (arvojournals.org)
  • In all, 1412 patients had complete data and constituted the study population. (wiley.com)
  • If a patient drops out of the study after the third week, then this value is "carried forward" and assumed to be his or her score for the 5 missing data points. (wikipedia.org)
  • Regulators see most of the trial data, but only from early on in a drug's life, and even then they don't give this data to doctors or patients, or even to other parts of government. (wikipedia.org)
  • research
  • A quasi-experimental research was carried out comparing 87 patients treated till 2000 ('old' strategy) with 87 patients treated from 2001 on ('new' strategy). (kuleuven.be)
  • It will also fund the Phase 3 research, which will include at least 230 patients. (nytimes.com)
  • Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by the British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. (wikipedia.org)
  • lower
  • This study evaluated two parallel interventions delivered in regular care: ICBT for tinnitus distress (n=293) and a low-intensity version of ICBT (n=81) for patients with lower levels of tinnitus distress. (diva-portal.org)
  • For help-seeking patients with lower distress, a low-intensity version of ICBT can be used. (diva-portal.org)
  • Additional
  • Additional enhancements include a motivational, personalized patient feedback report and a clinical report that provides guidance for Motivational Interviewing, a method known to be effective for improving engagement. (onlineprnews.com)
  • Doctors
  • As doctors try to ensure their patients do not abuse prescription drugs, they are relying more and more on sophisticated urine-screening tests to learn which drugs patients are taking and - just as important - which ones they're not. (nytimes.com)
  • Still, doctors say they now face tough choices about what to do with patients when tests show they are not taking prescribed drugs or are mixing them with unapproved drugs or illegal ones. (nytimes.com)
  • I think that it is problematic from an ethical perspective," for doctors to fire patients, said Dr. Chou, a professor at Oregon Health & Science University in Portland. (nytimes.com)
  • Medical cannabis, or medical marijuana, is cannabis and cannabinoids that are recommended by doctors for their patients. (wikipedia.org)
  • population
  • Based on the lowest estimated prevalence of pre-eclampsia of 3% and a test sensitivity of 93% and a test specificity of 97%, then to be 90% certain that the true specificity of the patient population is no less than 95%, a sample size of 4,800 participants is required. (clinicaltrials.gov)
  • However, by restricting the analysis to a selected patient population, it does not show the practical value of the new drug. (wikipedia.org)
  • whereas
  • Some patients prefer to be asked specific questions by the interviewer, whereas some patients prefer to open-endedly talk about their feelings. (wikipedia.org)
  • For instance, cancer patients will generally tolerate an immense amount of pain or discomfort during a chemotherapeutic study with the hope of prolonging survival or finding a cure, whereas patients experiencing a benign condition, such as a headache, will not. (wikipedia.org)
  • risk
  • And those who dropout are at greater risk of relapsing caught in a cycle with steep human and monetary costs. (onlineprnews.com)
  • Of note is the trend toward a reduction in the combined end point of hospitalizations and cardiac deaths (relative risk, 0.82 [CI, 0.65 to 1. P =.08), which was significant in patients with nonischemic etiology (relative risk, 0.56 [CI, 0.36 to 0. P =.01) and absent in the ischemic group (relative risk, 0.95). (ahajournals.org)
  • Patients with cancer who develop stroke are at high risk for future strokes or other clotting events. (clinicaltrials.gov)
  • A prediction of the caries risk showed that 16 of the evaluated 52 patients were considered as high risk patients. (diva-portal.org)
  • results
  • Results: Two patient drop outs with 4 restorations (2TEC, 2TC) were registered during the follow-up. (diva-portal.org)
  • However, it is also important that none of those involved in a clinical trial, whether the researcher, the subject patient or any other involved parties, should allow their own prior expectations to affect reporting of results. (wikipedia.org)
  • change
  • In patients without DM, the change in the number of superior zero blood flow pixels was not statistically significant (p=0.13), leading to a statistically significant difference between the two groups (p=0.0164). (arvojournals.org)
  • likely
  • For example, if an illicit drug is found, he will tell patients that the use of such a drug also means they are more likely to abuse the narcotic painkiller that he is prescribing them. (nytimes.com)
  • less
  • The marijuana cigarette protocol attracted only 119 patients, less than five percent of the total number enrolled in the Cannabis Therapeutic Program. (druglibrary.org)
  • suggests
  • The substantial reduction in the combined end point of cardiac death plus hospitalizations for heart failure in the nonischemic group suggests possible benefit in these patients. (ahajournals.org)