• A karyotype is the general appearance of the complete set of chromosomes in the cells of a species or in an individual organism, mainly including their sizes, numbers, and shapes. (wikipedia.org)
  • Karyotyping is the process by which a karyotype is discerned by determining the chromosome complement of an individual, including the number of chromosomes and any abnormalities. (wikipedia.org)
  • A karyogram or idiogram is a graphical depiction of a karyotype, wherein chromosomes are generally organized in pairs, ordered by size and position of centromere for chromosomes of the same size. (wikipedia.org)
  • Karyotypes describe the chromosome count of an organism and what these chromosomes look like under a light microscope. (wikipedia.org)
  • Six different characteristics of karyotypes are usually observed and compared: Differences in absolute sizes of chromosomes. (wikipedia.org)
  • A full account of a karyotype may therefore include the number, type, shape and banding of the chromosomes, as well as other cytogenetic information. (wikipedia.org)
  • Karyotyping is a test to examine chromosomes in a sample of cells. (medlineplus.gov)
  • Analysis of the morphometric features of B. pinnatum chromosomes was performed to establish their total length, the position of centromeres, and the position of BAC-based landmarks in relation to the centromere, thereby enabling their effective karyotyping, which is a prerequisite for more complex study of the grass genome structure and evolution at the cytomolecular level. (nih.gov)
  • Electrophoretic karyotyping is a relatively new experimental technique whereby the chromosomes of lower eukaryotes are physically separated in an agarose gel matrix by pulsed field gel electrophoresis (PFGE), stained with ethidium bromide, and visualized when irradiated with ultraviolet light. (taylorfrancis.com)
  • The key to obtaining high-resolution karyotypes resides in the identification of a successful method of preparing chromosomes for PFGE. (taylorfrancis.com)
  • That the number of chromosomes among field isolates of other fungal pathogens is variable is suggestive that aneuploidy may also play a significant role in karyotype variability. (taylorfrancis.com)
  • A karyotype test is a type of test usually done to determine changes in the chromosomes that may be related to certain blood disorders, genetic diseases, or cancer. (howmuchisit.org)
  • Chromosome18.org explained a karyotype test like this: "A karyotype is simply a picture of a person's chromosomes. (howmuchisit.org)
  • Together with the ribosomal DNA (rDNA), although without distinguishable chromosomes, a detailed karyotype was constructed for the six species. (au.dk)
  • G-banding is a technique used in cytogenetics to produce a visible karyotype by staining condensed chromosomes. (creative-bioarray.com)
  • Apart from conventional karyotyping, we can also provide Karyotyping of human chromosomes, mouse chromosomes by multicolor FISH probes . (creative-bioarray.com)
  • G-banding, G banding or Giemsa banding is a technique used in cytogenetics to produce a visible karyotype by staining condensed chromosomes. (blallab.com)
  • Karyotyping G-Banding and FISH for chromosomes 13,18, 21, X and Y. Detailed clinical history including anomaly scan report must be submitted with sample. (blallab.com)
  • If I calculate the N50 for measured chromosome lengths in a 1970s karyotype paper, it looks like N50 would be reached with the 7 largest chromosomes. (blogspot.com)
  • When an effective method of efficiently producing protoplasts is identified, the karyotypes may sometimes be characterized by diffuse bands with evidence of chromosomal fragments. (taylorfrancis.com)
  • We argue that the observed process of chromosome sorting would, if continued, result in a new homozygous chromosomal race, i.e., in a new karyotype with intermediate chromosome number and, possibly, in a new incipient homoploid hybrid species. (frontiersin.org)
  • We also discuss the segregational model of karyotype evolution and the chromosomal model of homoploid hybrid speciation. (frontiersin.org)
  • Students then diagnose the chromosomal aneuploidy based on the karyotype, list the symptoms associated with the disorder, and discuss the implications of the diagnosis. (ed.gov)
  • The blood cell karyotyping method was developed to provide information about chromosomal abnormalities. (genbiotech.net)
  • Karyotyping also may be done to find out whether chromosomal problems may have caused a fetus to be stillborn. (howmuchisit.org)
  • 1988. Modes of spontaneous chromosomal mutation and karyotype evolu-tion in ant wit reference to the minimum interaction hypotesis. (ptti.or.id)
  • 2, 44 had del17p, 36 had complex karyotype defined as the presence of ≥ 5 clonal chromosomal aberrations, and 67 out of 74 patients (90%) had unmutated VH -genes. (targetedonc.com)
  • We conclude that ongoing CIN is common in colorectal cancer organoids, and propose that CIN levels and the tolerance for mitotic errors shape aneuploidy landscapes and karyotype heterogeneity. (nature.com)
  • Karyotyping of cells obtained by either amniocentesis or CVS is the standard and definitive means of diagnosing aneuploidy in fetuses. (cdc.gov)
  • Karyotype tests should be repeated to confirm that an abnormal chromosome problem is actually in the body of the person. (medlineplus.gov)
  • Regardless of whether the karyotype test is normal or abnormal, you will usually need a follow-up appointment to discuss the results with your doctor. (howmuchisit.org)
  • If the results were abnormal, the doctor may also order other examinations that go together with the karyotype test, or the patient may need to start treatment for a certain condition. (howmuchisit.org)
  • Therapy-related myeloid neoplasms with normal karyotype show distinct genomic and clinical characteristics compared to their counterparts with abnormal karyotype. (uchicago.edu)
  • A sample of amniotic fluid was taken for karyotype analysis in 323 women and blood samples during pregnancy (209), at birth (105) and from the umbilical cord (97) and breast milk (47) were also collected. (cdc.gov)
  • Based on synteny analysis and high resolution DNA data from all known modern primates, scientists have proposed a karyotype for the common ancestor of all of these species. (jove.com)
  • The system enables users to locate images of interest by taxa, and to display the document with detailed information on species names, authors, year of the species publication, and karyotypes pictures in different colorations. (altmetric.com)
  • CIPEMAB has a wide range of applications, such as comparing various karyotypes of Brazilian species and identifying manuscripts of interest. (altmetric.com)
  • In this study, we aimed to construct a detailed karyotype of six Ipomoea species (hexaploid Ipomoea batatas and five related species, namely, one tetraploid, I. tabascana and four diploids, I. splendor-sylvae, I. trifida, I. tenuissima, and I. × leucantha) and understand the relationship among these species. (au.dk)
  • This study was conducted to obtain information about somatic chromosome numbers, karyotypes, and genome size of these five species. (ashs.org)
  • The results show significant differences in nuclear DNA content, chromosome number, and karyotype among three native and two introduced lantana species and will help to identify, preserve, protect, and use native lantana species. (ashs.org)
  • GenASIs Bandview is a software module for karyotyping diagnostics, offering cytogenetic labs with accurate, repeatable and standardized analysis. (dssimage.com)
  • GenASIs HiSKY performs Hyperspectral Karyotyping analysis, leveraging the benefits of multiplexed spectral imaging to obtain a karyotype which uniquely colors each chromosome and provides a level of detailed analysis not available with any other karyotyping technique. (dssimage.com)
  • Confirmation of a suspected 16q deletion in a dysmorphic child by flow karyotype analysis. (bmj.com)
  • Conclusive proof of the deletion was obtained by flow karyotype analysis of the patient and both parents, which showed that the deleted segment was approximately 7000 kb in size. (bmj.com)
  • Clinicopathologic and Molecular Analysis of Normal Karyotype Therapy-Related and De Novo Acute Myeloid Leukemia: A Multi-Institutional Study by the Bone Marrow Pathology Group. (stembook.org)
  • The output of enhancement method will be compared with result of Professional software for karyotyping analysis named Ikaros MetasystemT M . Based on experimental results, HE+BM3D method gets a stable result on both scenario noised and blur image. (neliti.com)
  • Creative Bioarray has performed many karyotyping (banded chromosome analysis) services for cell line authentication and some specific research. (creative-bioarray.com)
  • The peripheral blood lymphocyte culture is one of the most routinely used and traditional methods for karyotyping analysis. (geneticeducation.co.in)
  • Karyotype Analysis in Rice I. A New Method For Identifying All Chromosome Pairs. (ptti.or.id)
  • All patients with relapsed/refractory CLL should be evaluated for both complex karyotypes and del17p prior to initiating treatment, and all patients with complex karyotypes should be considered candidates for alternative combination therapy, according to the results of this analysis. (targetedonc.com)
  • The existence of both complex karyotypes and del17p had the worst impact on progression of disease in this analysis. (targetedonc.com)
  • The purpose of this analysis was to evaluate the impact of complex karyotype on short-term outcomes in patients with relapsed/refractory disease who were treated with single-agent ibrutinib in a single center. (targetedonc.com)
  • Karyotyping generally combines light microscopy and photography in the metaphase of the cell cycle, and results in a photomicrographic (or simply micrographic) karyogram. (wikipedia.org)
  • In metaphase where the karyotype is typically studied, all DNA is condensed, but most of the time, DNA with a high GC content is usually less condensed, that is, it tends to appear as euchromatin rather than heterochromatin. (wikipedia.org)
  • The chromosome in the pro-metaphase was analyzed for its karyotype morphology. (ptti.or.id)
  • The detection of a complex karyotype in addition to 17p deletion (del17p) appeared to be a strong predictor of early progression in patients with chronic lymphocytic leukemia (CLL) who received the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib (Imbruvica) as a single agent, according to a poster presented during the Virtual 25th Congress of the European Hematology Association. (targetedonc.com)
  • McConnell and coworkers assembled a brain copy number variation (CNV) atlas to reveal the frequency of neocortical neurons with complex karyotypes and the associated variability among individuals. (cellmicrosystems.com)
  • And please note that for cancer cells and in any cases where very complex, unstable karyotypes are observed. (creative-bioarray.com)
  • Entospletinib with decitabine in acute myeloid leukemia with mutant TP53 or complex karyotype: A phase 2 substudy of the Beat AML Master Trial. (uchicago.edu)
  • TP53 mutation defines a unique subgroup within complex karyotype de novo and therapy-related MDS/AML. (uchicago.edu)
  • Prognostic Significance of Complex Karyotypes in Acute Myeloid Leukemia. (uchicago.edu)
  • All patients with relapsed/refractory chronic lymphocytic leukemia should be evaluated for both complex karyotypes and del17p prior to initiating treatment, and all patients with complex karyotypes should be considered candidates for alternative combination therapy. (targetedonc.com)
  • Thirty-eight patients were detected with complex karyotypes, and 24 patients were associated with del17p. (targetedonc.com)
  • A strong association was observed between complex karyotypes and unmutated VH -genes ( P =.049), but no other associations observed in the study were significant. (targetedonc.com)
  • The median PFS was shorter at 34 months with the karyotype versus 40 months without complex karyotypes ( P =.0028), which the authors concluded was significantly shorter. (targetedonc.com)
  • The median PFS in patients with both complex karyotypes and del17p was 27 months versus 39 months in the rest of the patients ( P =.011). (targetedonc.com)
  • The proven and suspected cases of Richter syndrome and RUV were clustered among those with complex karyotypes in 6 (15%) and 2 (3%) of patients, respectively ( P =.06). (targetedonc.com)
  • Complex karyotype is a strong predictor of short-term progression in chronic lymphocytic leukemia patients treated with ibrutinib. (targetedonc.com)
  • We evaluated the characteristics of CCAAT/enhancer-binding protein α ( CEBPA ) mutations and the significance of a basic leucine zipper in-frame mutation (bZIP in-f ) of CEBPA in patients with acute myeloid leukemia with a normal karyotype. (e-crt.org)
  • CEBPA mutations occur in 7.5%-11% of cases of de novo acute myeloid leukemia (AML) and predominantly in patients with a normal karyotype (NK-AML) with 15%-18% [ 4 - 6 ]. (e-crt.org)
  • Fig. 4: Single-cell genome sequencing reveals karyotype heterogeneity in tumor PDOs. (nature.com)
  • The chromosome morphological structure was analyzed with karyotype maps using Image Raster, Corel Draw, and Microsoft Excel. (ptti.or.id)
  • Twenty-nine consecutive cases with a t(8;21)(q22;q22) in the bone marrow (BM) karyotype were retrospectively studied concerning clinical, morphological and cytogenetic data. (lu.se)
  • Chemotherapy may cause chromosome breaks that affect normal karyotyping results. (medlineplus.gov)
  • The purpose of this activity is to analyze a simulated karyotype, called an ideogram, in order to identify the genetic composition of both a normal cell and a cancerous cell. (flinnsci.com)
  • Karyotype testing is typically covered by most insurance companies as long as it was ordered by a licensed physician and is medically necessary. (howmuchisit.org)
  • A major step in harvesting cells for chromosome karyotyping is treatment with a hypotonic saline solution to increase cell volume. (genbiotech.net)
  • Our results showed a similar karyotype between I. tenuissima and I. × leucantha, indicating their close relationship. (au.dk)
  • The study of karyotypes is made possible by staining. (wikipedia.org)
  • This graph shows the total number of publications written about "Karyotype" by people in this website by year, and whether "Karyotype" was a major or minor topic of these publications. (uchicago.edu)
  • This classroom activity is based on a constructivist learning design and engages students in physically constructing a karyotype of three mock patients. (ed.gov)