• Buchman al, awal m, jenden d, roch m, kang s-h: The effect of lecithin supplementation on plasma choline concentrations during a marathon. (foodpharmacy.blog)
  • Although a great deal more work is required examining how pc ingestion relates to hcy concentrations, the limited data available indicates that pc supplementation, in high enough doses, may lower hcy concentrations. (foodpharmacy.blog)
  • Randomized controlled trials have demonstrated that supplementation with B vitamins, including vitamin B 6 , could effectively reduce homocysteine levels. (oregonstate.edu)
  • We investigated the ergogenic effects of betaine (B) supplementation on strength and power performance. (biomedcentral.com)
  • In the only study published to date on the effects of prolonged (14-15 days) betaine supplementation (1.25 g twice per day) on power performance, Hoffman and coworkers [ 6 ] reported no significant differences between betaine and placebo groups in the total repetitions performed to exhaustion at 75% 1RM, or in the number of repetitions performed at 90% of both peak and mean power, in the bench press exercise. (biomedcentral.com)
  • Considering the known importance of dietary betaine, the safety of betaine supplementation [ 2 ], and prevalence of betaine in foods typical of affluent American diets [ 9 ], this study aimed to further investigate the yet undefined ergogenic effects of betaine on resistance exercise, particularly on strength and power performance. (biomedcentral.com)
  • We hypothesized that betaine supplementation would be associated with improved strength and power in these individuals, thus demonstrating the potential efficacy of betaine in improving performance and recovery in strength and power exercise. (biomedcentral.com)
  • 0.05) on days 7-8 of betaine ingestion, and showed a similar trend (p = 0.06) on day 14-15, compared to the placebo group. (biomedcentral.com)
  • To begin identifying additional drivers of cognitive variability, the present study investigated choline, which affects the brain through several pathways. (biomedcentral.com)
  • CDP-Choline or its labelled metabolites are widely distributed, the cerebral radioactivity evolving in a different way from the blood which would confirm the inclusion of the product in the pool of phospholipids. (europa.eu)
  • Moreover, it seems taht there is a fixation of CDP- Choline or its metabolites in the structure components of the blood such as a red blood corpuscles and leukocytes, because these products are problably included in the metabolic processes of inclusion in cellular structures. (europa.eu)
  • The levels of methyl donors and related metabolites in plasma were quantitatively analyzed by high-performance liquid chromatography combined with mass spectrometry. (bvsalud.org)
  • The generalized estimation equation was used to analyze the relationship between maternal plasma methyl donors and related metabolites levels and neonatal outcomes of twins, and the generalized additive mixed model was used to analyze the relationship between maternal plasma methyl donors and related metabolites levels and fetal growth ultrasound indicators. (bvsalud.org)
  • Physical exercise significantly increased the plasma lactate concentration both after placebo and phosphatidylserine. (foodpharmacy.blog)
  • We previously demonstrated that intake of three eggs/d for 4 weeks increased plasma choline and decreased inflammation in subjects with metabolic syndrome (MetS). (mdpi.com)
  • The objective of this study was to determine if choline intake is correlated with working memory performance, and if this relationship is modified by diagnosis and metabolic control. (biomedcentral.com)
  • Recent and historical blood Phe concentrations were collected as measures of metabolic control. (biomedcentral.com)
  • Clinical monitoring of choline intake is essential for all individuals with PKU but may have important implications for working memory functioning among patients with good metabolic control. (biomedcentral.com)
  • Homocysteine is actually a by product of certain normal metabolic amino acid breakdown and processing. (ecopolitan.com)
  • There also is evidence of cross-talk between choline and energy metabolism [ 19 ], which may subsequently affect neurocognition by modulating fat deposition and insulin sensitivity [ 20 ]. (biomedcentral.com)
  • Suboptimal choline intake may contribute to these impairments, but this relationship has not been previously investigated in PKU. (biomedcentral.com)
  • Working memory performance was 0.32 z-scores (95% CI 0.06, 0.58) lower, on average, in participants with PKU compared to participants without PKU, and this difference was not modified by total choline intake (F[1,75] = 0.85, p = 0.36). (biomedcentral.com)
  • However, homocysteine lowering by B vitamins has failed to lower the risk of adverse cardiovascular outcomes in high-risk individuals. (oregonstate.edu)
  • A reduction in PLP availability appears to primarily affect kynureninase activity, limiting NAD production and leading to higher concentrations of kynurenine, 3-hydroxykynurenine, and xanthurenic acid in blood and urine ( Figure 2 ) (9) . (oregonstate.edu)
  • Later, on the blood concentration shows a trend to come back slowly to the initial values. (europa.eu)
  • Disruption of this pathway results in elevated blood Phe and reduced tyrosine (Tyr) concentrations, which lead to profound chemical and morphological changes in the brain [ 1 ]. (biomedcentral.com)
  • The purpose of the current study was to further explore the effects of phosphatidylcholine (PC) provided by eggs versus a choline bitartrate (CB) supplement on the gut microbiota, trimethylamine N-oxide (TMAO) formation, and plasma carotenoids lutein and zeaxanthin in MetS. (mdpi.com)
  • This was a cross-sectional study that included 40 adults with PKU and 40 demographically matched healthy adults. (biomedcentral.com)
  • As there's such a high concentration of ingredients in this formula we were really happy with how the flavor systems turned out. (moreplatesmoredates.com)
  • There also was a trend, albeit nonsignificant ( p = 0.10), for this association to be attenuated with increased Phe concentrations. (biomedcentral.com)
  • In Japan this probiotic is used in humans and more recently as an additive to animal feed, to produce healthier, bigger, chickens and pigs. (epiphanyasd.com)
  • 7. Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine. (nih.gov)
  • 8. Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism. (nih.gov)
  • 14. Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations. (nih.gov)
  • 15. Evidence of choline depletion and reduced betaine and dimethylglycine with increased homocysteine in plasma of children with cystic fibrosis. (nih.gov)
  • 18. Quantification of acetylcholine, choline, betaine, and dimethylglycine in human plasma and urine using stable-isotope dilution ultra performance liquid chromatography-tandem mass spectrometry. (nih.gov)
  • 19. Measurement of concentrations of whole blood levels of choline, betaine, and dimethylglycine and their relations to plasma levels. (nih.gov)
  • The quaternary ammonium compounds, choline and betaine, and dimethylglycine (DMG) reside along a metabolic pathway linked to the synthesis of neurotransmitters and membrane phospholipids and to homocysteine remethylation and, therefore, folate status. (nih.gov)
  • Our Products with Betaine anhydrous in them. (eupepwell.com)
  • Betaine anhydrous is a chemical that occurs naturally in the body. (eupepwell.com)
  • Betaine anhydrous is approved by the U.S. Food and Drug Administration (FDA) for treatment of high urine levels of a chemical called homocysteine ( homocystinuria ) in people with certain inherited disorders. (eupepwell.com)
  • Betaine anhydrous supplements are most commonly used for reducing blood homocysteine levels and trying to improve athletic performance. (eupepwell.com)
  • Betaine anhydrous helps in the metabolism of a chemical called homocysteine. (eupepwell.com)
  • Betaine anhydrous prevents the buildup of homocysteine in the blood. (eupepwell.com)
  • Taking betaine anhydrous lowers homocysteine levels in the urine. (eupepwell.com)
  • Betaine anhydrous is FDA approved for treating this condition in both children and adults. (eupepwell.com)
  • Using betaine anhydrous in a toothpaste seems to reduce symptoms of dry mouth. (eupepwell.com)
  • Also, using mouthwash containing betaine anhydrous, xylitol, and sodium fluoride seems to improve dry mouth symptoms. (eupepwell.com)
  • Research shows that taking betaine anhydrous can decrease homocysteine levels in the blood of some people. (eupepwell.com)
  • Taking betaine anhydrous does not seem to prevent seizures or improve mental function in children with Angelman syndrome. (eupepwell.com)
  • Early research has found that higher dietary intake of betaine anhydrous is not linked with a reduced risk of colon and rectum tumors. (eupepwell.com)
  • Early research shows that taking betaine anhydrous along with s-adenosyl-L-methionine (SAMe) improves symptoms of depression in more people than does taking the antidepressantamitriptyline. (eupepwell.com)
  • Some research suggests that betaine anhydrous can improve certain aspects of exercise performance, including body composition and strength, in men who participate in strength training. (eupepwell.com)
  • However, betaine anhydrous does not seem to improve strength in untrained men or women. (eupepwell.com)
  • Early research suggests that taking betaine anhydrous, along with melatonin, L-tryptophan, vitamin B6, folic acid, vitamin B12, and methionine daily can reduce symptoms of acid reflux. (eupepwell.com)
  • Hepatitis C. Early research shows that taking betaine anhydrous (Cystadane) plus S-adenosyl-L-methionine along with hepatitis C medications can reduce the amount of active virus in people with hepatitis C who did not respond to treatment with hepatitis C medications alone. (eupepwell.com)
  • Developing research has found that betaine anhydrous might improve liver disease in people with NASH. (eupepwell.com)
  • Early research has found that applying a specific betaine anhydrous-containing cream for one month before exposure to sunlight reduces sunburn. (eupepwell.com)
  • Early research shows that taking a combination of folate and betaine anhydrous daily for 12 months does not improve growth, development, or function in girls with Rett syndrome. (eupepwell.com)
  • In one small study, adding betaine anhydrous to a low-calorie diet did not produce extra weight loss in obese adults. (eupepwell.com)
  • More evidence is needed to rate the effectiveness of betaine anhydrous for these uses. (eupepwell.com)
  • Betaine anhydrous is LIKELY SAFE for most children and adults when taken by mouth appropriately. (eupepwell.com)
  • Betaine anhydrous can cause some minor side effects. (eupepwell.com)
  • Betaine anhydrous (trimethylglycine) is a naturally occurring byproduct of sugar beet refinement that may improve changes in body composition and muscular performance during a resistance training protocol [ 1 ]. (springer.com)
  • 11. The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway. (nih.gov)
  • Folate and choline are methyl-donor nutrients and are important for closure of the neural tube during fetal development. (bvsalud.org)
  • High homocysteine levels in the urine (homocystinuria). (eupepwell.com)
  • A reduction in PLP availability appears to primarily affect kynureninase activity, limiting NAD production and leading to higher concentrations of kynurenine, 3-hydroxykynurenine, and xanthurenic acid in blood and urine ( Figure 2 ) (9) . (oregonstate.edu)
  • 2. DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. (nih.gov)
  • but, whether betaine enhances body composition or performance in female subjects is currently unknown. (springer.com)
  • 6. Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery. (nih.gov)
  • Although some human studies have reported associations between maternal folate and choline levels and child cognitive outcomes, results are not consistent, and no human studies have investigated the potential interactive effects of folate and choline. (bvsalud.org)
  • This narrative review discusses and critically reviews current research examining the associations between maternal levels of folate and choline during pregnancy and brain and cognitive development in children. (bvsalud.org)
  • Change in mean metabolite concentration across pregnancy (M1 to M3) was significantly different for S-adenosylhomocysteine (SAH), S-adenosylmethionine (SAM), betaine, and choline. (bvsalud.org)
  • 5. Homocysteine-lowering vitamins do not lower plasma S-adenosylhomocysteine in older people with elevated homocysteine concentrations. (nih.gov)
  • 1 LOCUS for Homocysteine and Related Vitamins, University of Bergen, N-5021 Bergen, Norway. (nih.gov)
  • However, homocysteine lowering by B vitamins has failed to lower the risk of adverse cardiovascular outcomes in high-risk individuals. (oregonstate.edu)
  • A trend ( p = .056) was found for greater weekly training volumes for betaine versus placebo. (springer.com)
  • High homocysteine levels are associated with heart disease , weak bones ( osteoporosis ), skeletal problems, and eye lens problems. (eupepwell.com)
  • High homocysteine levels in the blood (hyperhomocysteinemia). (eupepwell.com)
  • Taking betaine along with folic acid doesn't reduce blood homocysteine levels better than taking folic acid alone. (eupepwell.com)
  • High levels of circulating homocysteine are associated with an increased risk of cardiovascular disease . (oregonstate.edu)
  • These elements, in combination with the high levels of pure protein it provides to your body with practically zero fats and lactose, make it ideal for those who want to nourish their body and promote a healthy lifestyle. (savagesupps.com)
  • We thus investigated the associations of plasma levels of trimethylamine N-oxide (TMAO), choline, and betaine with anthropometric measurements, including modulatory effects of genetics and diet. (bvsalud.org)
  • This lack of consistency could be due to differences in the methods used to assess folate and choline levels, the gestational trimester at which they were measured, and lack of consideration of potential confounding variables. (bvsalud.org)
  • It generally has a higher concentration of protein than other forms of whey, such as concentrated whey protein. (savagesupps.com)
  • Plasma concentrations of choline, betaine, and TMAO were determined using reverse-phase ultra-high-performance liquid chromatography electrospray ionisation mass spectrometry. (bvsalud.org)
  • Betaine in dosages of 2.5 g/day for 14 days to 6 weeks has shown potential to enhance strength-based performance [ 1 ]. (springer.com)