Positive signals for TUNEL were detected in epithelioid histiocytes and lymphocytes within granulomas and in bronchoalveolar lavage (BAL) lymphocytes from patients with sarcoidosis. (ersjournals.com)
Apoptosis in epithelioid histiocytes and inflammatory cells seems to participate in the course of granulomatous inflammation. (ersjournals.com)
Moreover, cutaneous biopsy, which was performed on the right forearm, revealed granulomas with epithelioid histiocytes and Langerhans-type giant cells. (who.int)
Macrophages3
Macrophages and dendritic cells are derived from common bone marrow precursor cells that have undergone different differentiation (as histiocytes) under the influence of various environmental (tissue location) and growth factors such as GM-CSF, TNF and IL-4. (wikipedia.org)
These features may be responsible for the recruitment and activation of T cells, macrophages and dendritic cells, characterizing the stromal component of this lymphoma, and may point towards innate immunity and a tumor tolerogenic immune response in T-cell/histiocyte-rich large B-cell lymphoma. (haematologica.org)
SIV antigen has been demonstrated by immunohistochemical methods in lymph node sinus histiocytes, macrophages, and giant cells (14) as well as in macrophage-derived cells in brain tissue from diseased monkeys (8). (cdc.gov)
Mononuclear phagoc1
They circulate through the body and enter various organs, where they undergo differentiation into histiocytes, which are part of the mononuclear phagocytic system (MPS). (wikipedia.org)
Langerhans4
Some sources consider Langerhans cell derivatives to be histiocytes. (wikipedia.org)
The most common histiocyte disorders are Langerhans' cell histiocytosis and haemophagocytic lymphohistiocytosis. (wikipedia.org)
The rare histiocytic disorders (RHD), or non-Langerhans cell disorders, are a diverse group of disorders defined by the accumulation of histiocytes that do not meet the criteria for Langerhans cell histiocytosis (LCH) or hemophagocytic lymphohistiocytosis (HLH). (histiocytesociety.org)
It is found on Langerhans cells, follicular dendritic cells and histiocytes. (beckman.com)
Granulomas1
When lung tissue becomes inflamed from an infection or other cause, cells called histiocytes cluster to form nodules called granulomas. (healthline.com)
Lymphocytes3
In 1994, after three years of progressive neurological dysfunction, diagnosis of Erdheim-Chester disease was made by analysis of biopsies of the femur bones, showing infiltration with foamy histiocytes lacking Birbeck granules and S-100 protein, and with few lymphocytes. (bmj.com)
Infiltrate composed of lymphocytes and histiocytes. (cdlib.org)
2002). The most common manifestation is chronic interstitial pneumonitis with infiltration of lymphocytes, histiocytes, and plasma cells (Saltini and Amicosante 2001). (cdc.gov)
The histiocyte is a tissue macrophage or a dendritic cell (histio, diminutive of histo, meaning tissue, and cyte, meaning cell). (wikipedia.org)
However, the term histiocyte has been used for multiple purposes in the past, and some cells called "histocytes" do not appear to derive from monocytic-macrophage lines. (wikipedia.org)
Cells10
Histiocytosis is a group of conditions that involve too many white blood cells (histiocytes) in your child's blood. (childrensnational.org)
There was also a lesion with foamy histiocyte-like cells corresponding to the white lesion in the face of the cut tumor. (karger.com)
Sea-blue histiocytes and Gaucher cells in bone marrow of patients with chronic myeloid leukaemia. (bmj.com)
The aggressive T-cell/histiocyte-rich large B-cell lymphoma and the indolent nodular lymphocyte-predominant Hodgkin's lymphoma are both characterized by a paucity of tumor cells embedded in an overwhelming background. (haematologica.org)
4 In the World Health Organization (WHO) classification of 2001, T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) is defined by the presence of a limited number of scattered large B cells in a background rich in T cells, with or without histiocytes. (haematologica.org)
Histiocytoses are rare diseases caused by an excess of cells called histiocytes, which can infiltrate the skin, bones, lungs, liver, spleen and the central nervous system. (histiocytesociety.org)
Other patterns include arrangement of the histiocytes in cords or single cells that percolate between benign prostatic glands. (medscape.com)
Histiocytosis is an umbrella term that refers to a relatively uncommon group of syndromes associated with the overproduction of certain infection-fighting white blood cells known as histiocytes. (tgh.org)
Normal histiocytes originate from pluripotent stem cells, which can be found in bone marrow. (medscape.com)
Disorders6
Children's National offers the highest level of experience with histiocyte disorders in the entire Washington, D.C. area. (childrensnational.org)
We also collaborate with care providers from all over the world who are also involved in the field of histiocyte disorders, allowing us access to national and international approaches to treatment. (childrensnational.org)
We participate in research treatment protocols with select institutions around the country who are investigating the newest approaches using the latest scientific advances for histiocyte disorders. (childrensnational.org)
Physicians, patients and parents of children with rare histiocytoses frequently consult members of the Histiocyte Society on the management of these disorders. (histiocytesociety.org)
The Histiocyte Society is a nonprofit organization of more than 200 physicians and scientists from around the world committed to improving the lives of patients with histiocytic disorders by conducting clinical and laboratory research into the causes and treatment of this disease. (histiocytesociety.org)
He has a special interest in neuroblastoma and histiocyte disorders. (chop.edu)
Histiocytoses1
Histiocytoses describe neoplasias wherein the proliferative cell is the histiocyte. (wikipedia.org)
Foamy2
This report describes the case of a patient with a morphologically distinctive pattern of HCC with prominent cell cytoplasm that had a foamy histiocyte-like appearance. (karger.com)
1 It is associated with tissue infiltration by foamy histiocytes. (bmj.com)
Accumulation3
Rosai-Dorfman disease is a rare disorder characterized by overproduction (proliferation) and accumulation of a specific type of white blood cell (histiocyte) in the lymph nodes of the body (lymphadenopathy), most often those of the neck (cervical lymphadenopathy). (rarediseases.org)
In some cases, abnormal accumulation of histiocytes may occur in other areas of the body besides the lymph nodes (extranodal). (rarediseases.org)
In some cases of Rosai-Dorfman disease, the accumulation of histiocytes into masses may cause compression of vital organs potentially resulting in serious complications. (rarediseases.org)
Inflammatory1
The histiocytes do not incite an inflammatory reaction. (medscape.com)
Bone marrow1
Histiocytes are derived from the bone marrow by multiplication from a stem cell. (wikipedia.org)
Immune3
These histiocytes are part of the immune system by way of two distinct functions: phagocytosis and antigen presentation. (wikipedia.org)
Conclusions The gene expression profile of T-cell/histiocyte-rich large B-cell lymphoma, in comparison with that of nodular lymphocyte-predominant Hodgkin's lymphoma, shows features suggestive of a distinct tolerogenic host immune response that may play a key role in the aggressive behavior of this lymphoma, and that may serve as a potential target for future therapy. (haematologica.org)
The goal is to inhibit the overproduction of histiocytes by suppressing the immune system. (tgh.org)
Lymph1
Results We observed that the microenvironment in nodular lymphocyte-predominant Hodgkin's lymphoma is molecularly very similar to a lymph node characterized by follicular hyperplasia, while the microenvironment in T-cell/histiocyte-rich large B-cell lymphoma is clearly different. (haematologica.org)
Proliferation2
Malignant histiocytosis is a rare invasive proliferation of neoplastic histiocytes. (bmj.com)
A zone of fibroblastic proliferation with palisading histiocytes may surround the area. (merckmanuals.com)
Monocyte1
The term Histiocyte can also simply refer to a cell from monocyte origin outside the blood system, such as in a tissue (as in rheumatoid arthritis as palisading histiocytes surrounding fibrinoid necrosis of rheumatoid nodules). (wikipedia.org)
Biopsies1
Biopsies demonstrated aggregates of histiocytes with granular eosinophilic material in the lamina propria. (asn-online.org)
Cytoplasm1
Prostatic xanthoma comprises collections of histiocytes with finely vacuolated, lipid-laden cytoplasm. (medscape.com)
Society3
Abstracts that include data from ongoing Histiocyte Society studies will not be considered for presentation. (histiocytesociety.org)
This involves leadership roles within the Children's Oncology Group (COG), the International Neuroblastoma Risk Group (INRG), and the International Histiocyte Society. (chop.edu)
The information on this page has been written and reviewed by the Histiocytosis Association Board of Trustees Scientific Committee and a member of the Histiocyte Society , and subsequently audited by patients and families to ensure enough information was captured. (histio.org)
Kikuchi-Fujimoto Disease: An Exuberant Localized T Cell Activation Arrested By Histiocytes? (medscape.com)
Cite this: Kikuchi-Fujimoto Disease: An Exuberant Localized T Cell Activation Arrested By Histiocytes? (medscape.com)
Correa H. Kikuchi-Fujimoto Disease: An Exuberant Localized T Cell Activation Arrested By Histiocytes? (medscape.com)
Form1
We are one of only 10 programs in the world using an aggressive new form of chemotherapy to treat histiocytes. (childrensnational.org)
Reaction1
By quantitative reverse transcriptase polymerase chain reaction we verified that these 20 selected cases were representative of the entire population of T-cell/histiocyte-rich large B-cell and nodular lymphocyte-predominant Hodgkin's lymphomas. (haematologica.org)
Cases1
Design and Methods We collected 33 cases of T-cell/histiocyte-rich large B-cell lymphoma and 56 cases of nodular lymphocyte-predominant Hodgkin's lymphoma and performed microarray gene expression profiling on ten cases of each lymphoma, to obtain a better understanding of the lymphoma host response. (haematologica.org)
Presence1
One immunoglobulin was presented in the histiocytes, suggesting the antecedent presence of antigen-antibody complexes. (cdc.gov)
Categories1
The various categories of histiocytes are distinguishable by their morphology, phenotype, and size. (wikipedia.org)
Field1
We are one of only 10 programs in North America advancing the field of histiocyte disorder care. (childrensnational.org)
Shows1
This graph shows the total number of publications written about "Histiocytes" by people in this website by year, and whether "Histiocytes" was a major or minor topic of these publications. (ouhsc.edu)