Chemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and Processes
Heterocyclic CompoundsHeterocyclic Compounds, Bridged-RingNitrogen CompoundsCyclizationHeterocyclic Compounds, 2-RingPalladiumHeterocyclic Compounds with 4 or More RingsHeterocyclic Compounds, 3-RingMolecular StructureHeterocyclic Compounds, 1-RingMagnetic Resonance Spectroscopy
DerivativesFive-memberedAtomsContaining an unfusedBiologically activeSulfur CompoundsClass of organic compoundsSynthesisTriazinesChemistryBenzeneSubstituentsOxidesOrganic chemical compound with thSeries of novelMoietyPotentPurineBicyclicBenzoUreidoSubclassAcidsCarcinogenicMethylStructuresSubstancesCarboxyl groupTherapeuticSolubilityAntibacterialFunctional groupCarbonAtomBiotinAminesOxygenMeSHCarboxylic
Derivatives11
  • Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. (umassmed.edu)
  • The hydrogen on the 1-bit nitrogen atom can be transferred to the 3-atom, therefore, imidazole derivatives with same substituent respectively on 4-bit and 5-bit are tautomers. (lookchem.com)
  • For example, pyrimidine ring turns into purine derivatives after condensation. (lookchem.com)
  • The compounds, 5-Nitrosalicylaldehyde and 5-Bromosalicylaldehyde are halogenated derivatives of an aldehyde-phenol (Salicylaldehyde) indicated for use as pharmaceutical intermediates. (faqs.org)
  • Reaction of tetrafluoropyridazine with catechol gives a tricyclic 9,10-dioxa-1,2-diaza-anthracene system by a sequential nucleophilic aromatic substitution ring annelation process, further extending the use of perfluoroheteroaromatic derivatives for the synthesis of unusual polyfunctional heterocyclic architectures. (beilstein-journals.org)
  • Isatin (1-H-indole-2,3- dione) and its derivatives possess diverse biological and pharmacological activities and are widely used as a starting material for the synthesis of a broad range of heterocyclic compound substrates for drug synthesis [ 1 ]. (ijpsonline.com)
  • By observing the importance of the above said problem, the isatin-based Schiff base and spiro isatin derivatives of spirothiozolidin- 4-ones and 5'-methyl-spiro-4-thiazolidiones from 5-substituted isatin and 2-benzoyl-4-chloroaniline were synthesized following the steps given in Figures 1 and 2 . (ijpsonline.com)
  • Seven compounds inhibited the growth of some cancer cell lines, whereas one of the 2-quinoline derivatives displayed favorable activity against all tested cancer cells with GI 50 values of 0.92-13 μM. (springer.com)
  • These findings prompted us to extend our search for biologically active compounds among nitrogen heterocyclic derivatives. (springer.com)
  • Pyridine derivatives with one or more keto groups on the ring. (jefferson.edu)
  • Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential. (rtrn.net)
Five-membered2
Atoms9
  • B. Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring. (uncommondescent.com)
  • Thiophene is 5-membered ring consisting of four carbon atoms and one sulfur atom. (drugbank.com)
  • Imidazolidine is 5-membered saturated ring of three carbon atoms, and two nitrogen centers at the 1- and 3-positions. (drugbank.com)
  • A valeric acid substituent is attached to one of the 2 carbon atoms of the tetrahydrothiophene ring. (medscape.com)
  • One of the three diazines (six-membered heterocyclics with two nitrogen atoms in the ring), it has the nitrogen atoms at positions 1 and 3 in the ring. (gda.pl)
  • the flexibility of the Cu(110)-O structure … [117] The numbering of the ring atoms in pyridine starts at the nitrogen (see infobox). (gda.pl)
  • 6-membered aromatic rings with one carbon replaced by another group: 6-membered rings with two nitrogen atoms: 6-membered rings with three nitrogen atoms: 6-membered rings with four nitrogen atoms: 6-membered rings with five nitrogen atoms: 6-membered rings with six nitrogen atoms: This page was last edited on 29 November 2020, at 18:47. (gda.pl)
  • In organic chemistry, Pyridazines are a subclass of organic compounds in the diazines class in the organoheterocyclic compound superclass , containing a pyridazine ring, (a six-member aromatic ring containing two nitrogen atoms at positions 1 and 2, and four carbon atoms). (wellnessadvantage.com)
  • Biotin is a bicyclic (more precisely, heterocyclic) compound composed of an ureido ring (A) fused with a tetrahydrothiophene ring (B). A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. (medscape.com)
Containing an unfused1
  • The applicable subheading for Trichloromelamine will be 2933.69.6021 , Harmonized Tariff Schedule of the United States (HTSUS), which provides for Heterocyclic compounds with nitrogen hetero-atom(s) only: Compounds containing an unfused triazine ring (whether or not hydrogenated) in the structure: Other: Other: Pesticides: Other. (faqs.org)
Biologically active1
  • The Hamme research group is interested in the synthesis of biologically active heterocyclic containing natural products and their synthetic analogues. (jsums.edu)
Sulfur Compounds4
  • Liquid density of different kinds of organic sulfur compounds with varying carbon number (20°C/68°F). Comparison of thiols, sulfides, disulfides and thiophenes. (engineeringtoolbox.com)
  • Tables and figures below show the liquid density at 20°C for different groups of organic sulfur compounds , compared to other kinds of organic classes as alkanes, alcohols, acids and amines . (engineeringtoolbox.com)
  • Also, examples of the structures of the sulfur compounds thiols, dialkyl sulfides, methylalkyl sulfides, ethyl alkyl sulfides, isopropyl alkyl sulfides, diisoalkyl sulfides, dialkyl disulfides and alkylthiophenes are shown in the table below. (engineeringtoolbox.com)
  • See also density for n-alkanes, alcohols and acids and density, boiling and melting points of nitrogen and sulfur compounds. (engineeringtoolbox.com)
Class of organic compounds2
  • A class of organic compounds containing three ring structures, one of which is made up of more than one kind of atom, usually carbon plus another atom. (harvard.edu)
  • This compound belongs to the class of organic compounds known as thienoimidazolidines. (drugbank.com)
Synthesis7
  • Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;Biochemistry;Reagents for Oligosaccharide Synthesis;Highly Purified Reagents;Other Categories;Zone Refined Products;Buffer;ACS Grade Buffers;ACS Grade;Biological Buffers;Buffers A to Z;Building Blocks;C3 to C8;Chemical Synthesis;Essential Chemicals;Heterocyclic Building Blocks;Imidazoles;Inorganic Salts;Research Essentials;Solutions and Reagents;Intermediate for Propafenone hydrochloride. (lookchem.com)
  • The compound, Di-tert-butyl dicarbonate, also known as Dicarbonic acid, bis(1,1-dimethylethyl) ester, is an ester of an inorganic acid indicated for use as a reagent in organic synthesis. (faqs.org)
  • Drug discovery programmes are continually searching for viable synthetic routes to highly novel classes of heterocyclic compounds with the aim of exploring chemical 'drug-like' space [1] and uncovering valuable biological activity for hit-to-lead generation of new chemical entities by parallel synthesis techniques. (beilstein-journals.org)
  • Methodology for the ready synthesis of new organic frameworks is still required and, in this context, heterocyclic scaffolds based on novel molecular architecture that bear multiple functionality and can be rapidly processed into many analogues by parallel synthesis are particularly valuable [5,6] . (beilstein-journals.org)
  • Isatin is synthetically a versatile substrate that can be used for the synthesis of large variety of heterocyclic compounds. (ijpsonline.com)
  • We undertook the synthesis of structures that were condensates of heterocyclic methyl carbimidates with 2-chlorobenzenesulfonamide and 4-chloropyridine-3-sulfonamide. (springer.com)
  • 2-Bromopyridine is an organic compound with the formula BrC 5 H 4 N. It is a colorless liquid that is used as an intermediate in organic synthesis.It can be prepared from 2-aminopyridine via diazotization followed by bromination. (gda.pl)
Triazines2
  • It is a six-membered heterocyclic aromatic ring, one of several isomeric triazines. (wikipedia.org)
  • Symmetrical 1,3,5-triazines are prepared by trimerization of certain nitriles such as cyanogen chloride or cyanimide. (wikipedia.org)
Chemistry4
  • Chemistry of Heterocyclic Compounds. (wikipedia.org)
  • Heterocyclic chemistry is of great importance to the medicinal chemists because of their utility in medicine. (ijpsonline.com)
  • In organic chemistry, Phthalazines are a subclass of aromatic heterocyclic organic compounds in the benzodiazines subclass in the diazanaphthalenes class in the organoheterocyclic compound superclass , containing a phthalazine moiety, consisting of a benzene ring fused to a pyridazine, forming a 2,3-benzodiazine skeleton. (wellnessadvantage.com)
  • In organic chemistry, Pyridazinones are organic compounds in the pyridazines subclass in the diazines class in the organoheterocyclic compound superclass , containing a pyridazine ring which bears a ketone. (wellnessadvantage.com)
Benzene1
  • It may be formally derived from the structure of benzene through the exchange of one ring carbon for a nitrogen. (gda.pl)
Substituents1
  • The compounds with aromatic N-heterocyclic substituents at the 4-position of pyrazolyl ring showed better antibacterial activity against the tested bacteria than other compounds with different patterns of substitution. (figshare.com)
Oxides1
  • N-oxides are stable dipolar species with the electrons on oxygen delocalised round the pyridine ring, raising the HOMO of the molecule. (gda.pl)
Organic chemical compound with th1
  • 1,3,5-Triazine, also called s-triazine, is an organic chemical compound with the formula (HCN)3. (wikipedia.org)
Series of novel2
  • A series of novel teraryl oxazolidinone compounds was designed, synthesized, and evaluated for their antimicrobial activity and toxicities. (figshare.com)
  • A series of novel heterocyclic sulfonyl-carboximidamides were synthesized in satisfactory yields via condensation of heterocyclic methyl carbimidates with 2-chlorobenzenesulfonamide and 4-chloropyridine-3-sulfonamide. (springer.com)
Moiety1
  • This compound has a chlorine atom in its structure linked to the quinoxaline ring (C-5) substituted at the C-2 position with a sulfanilamide moiety. (springer.com)
Potent2
  • Among all potent compounds, 10f exhibited promising safety profile in MTT assays and in hERG K + channel inhibition test. (figshare.com)
  • Compound A02 found to possess potent antioxidant activity compared to the standards ascorbic acid and butylated hydroxytoluene. (ijpsonline.com)
Purine1
  • A purine is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. (uncommondescent.com)
Bicyclic1
  • Biotin is a bicyclic molecule composed of a ureido ring fused with a tetrahydrothiophene ring. (medscape.com)
Benzo1
  • These are aromatic heterocyclic compound containing the Benzo[b]thiophene ring system. (drugbank.com)
Ureido1
  • The ureido ring is involved in the high affinity binding of biotin to avidin, a glycoprotein found in egg-white. (medscape.com)
Subclass1
  • Justia Patents Organic Compounds -- Part Of The Class 532-570 Series Patents Organic Compounds (class 532, Subclass 1) Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e. (justia.com)
Acids1
  • Almost all organisms are protected to some extent against free radicals such as peroxide, hydroperoxide and lipid peroxyl damage by enzymes such as superoxide dismutase and catalase or compounds such as ascorbic acid (AA), tocopherols, phenolic acids, polyphenols, flavonoids and glutathione [ 16 ]. (ijpsonline.com)
Carcinogenic1
  • These compounds are toxic, potentially carcinogenic and mutagenic properties even at low concentration of NHCs in the aqueous stream [ 2 ]. (eeer.org)
Methyl2
  • Spirothiozolidin-4-ones and 5'-methyl-spiro-4-thiazolidiones were synthesized Schiff's bases of isatins by treating with thioglycolic acid and thiolactic acid, respectively in the presence of 1,4-dioxane and anhydrous zinc chloride. (ijpsonline.com)
  • Workers at coal-tar produc- pyrene, is classified as carcino- sene, 3-methylchrysene, 4-methyl- tion plants, coking plants, bitumen genic to humans (Group 1). (who.int)
Structures2
  • The structures of the synthesized compounds were characterized by elemental and spectral analysis. (ijpsonline.com)
  • The purity of the compounds was monitored by thin layer chromatography (TLC) and the structures of the products were confirmed by elemental and spectral analysis. (ijpsonline.com)
Substances1
  • Spirocyclic systems containing one common carbon atom to two rings are structurally interesting [ 10 ] and naturally occurring substances being known for their wide range of biological activities [ 11 , 12 ]. (ijpsonline.com)
Carboxyl group1
Therapeutic1
Solubility2
  • Because of nitrogen-atom included in the ring system, these compounds have high water solubility. (eeer.org)
  • more rings have low solubility in wa- phases of tissues. (who.int)
Antibacterial3
  • All the compounds were screened for their tuberculostatic, antibacterial, and anticancer activities. (springer.com)
  • Preliminary results indicated that target compounds exhibited weak tuberculostatic and antibacterial activities. (springer.com)
  • The synthesized compounds were evaluated for their biological activity in vitro: tuberculostatic, antibacterial, cytotoxic, and anticancer. (springer.com)
Functional group2
  • The amidine functional group is an important structural element of compounds with established pharmacological activity. (springer.com)
  • A compound or functional group that contain a basic nitrogen atom with a lone pair. (engineeringtoolbox.com)
Carbon5
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Chalcogen (i.e. (justia.com)
  • The present study investigates the feasibility of nitrogenous heterocyclic compounds (NHCs) (Pyridine-Quinoline) degradation by catalytic wet peroxidation (CWPO) in the presence of nanoscale zerovalent iron supported on granular activated carbon (nFe 0 /GAC) using statistical optimization technique. (eeer.org)
  • The density is shown as function of carbon number in the organic compounds. (engineeringtoolbox.com)
  • An organic compound consisting entirely of hydrogen and carbon. (engineeringtoolbox.com)
  • An organosulfur compound that contains a carbon-bonded sulfhydryl group (-SH), with the general formula R-SH (where R represents an alkyl or other organic substituent). (engineeringtoolbox.com)
Atom3
  • The unshared electron pair of 1-bit nitrogen atom in imidazole ring participates in the cyclic conjugation, reduces the electron density of the nitrogen atom, and makes hydrogen of the nitrogen atom easily leave in the form of hydrogen. (lookchem.com)
  • The unshared electron pair of 3-bit nitrogen atom in imidazole ring doesn't participates in the cyclic conjugation, while it occupies the sp2 hybridized orbital, can accept protons, and form salt with strong acid. (lookchem.com)
  • The subject of this work was to study the reactions of heterocyclic carbimidates with sulfonamides that have a chlorine atom as a substituent in the ortho position to the sulfonamide group. (springer.com)
Biotin1
  • Later, the protective compound in the foodstuffs was identified as biotin. (medscape.com)
Amines2
  • The tricyclic scaffold reacts with amines and sodium ethoxide providing a short series of functional 9,10-dioxa-1,2-diaza-anthracene systems. (beilstein-journals.org)
  • For 1-amines in this document the R represents an alkyl group, in which the NH2-group is placed at the end of the the alkane chain. (engineeringtoolbox.com)
Oxygen1
  • Oxygen containing hetero ring (e.g., dioxirane, etc. (justia.com)
MeSH1
  • Heterocyclic Compounds, 3-Ring" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
Carboxylic1
  • The structure of niacin contains a pyridine ring with a carboxylic acid at the meta position. (gda.pl)